Click-Murmur Syndrome

Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.

Synonym
Mitral Click-Murmur Syndrome
Click-Murmur Syndrome
Mitral Valve Prolapse
Mitral Valve Prolapse Syndrome
Floppy Mitral Valve
Prolapsed Mitral Valve
Systolic Click-Murmur Syndrome

Excerpt	Reference
"Mitral valve prolapse is usually a benign condition, however, serious complications have been reported to be associated with it."	( Bergh, PA; Breen, JL; Gregori, CA; Hollander, D, 1988)
"Mitral valve prolapse is a very common condition."	( Gopalaswamy, C; Gould, L, 1984)
"Mitral valve prolapse is a common cardiac anomaly in which diagnosis is generally made by auscultation."	( de Leon, AC, 1980)
"Mitral valve prolapse is the most frequent cardiac valvulopathy."	( Infante, B; Palma, MA; Ruiz-Castro, M; Sanz, M; Vidal, A, 1996)
"Mitral valve prolapse is more frequent in hyperthyroid patients than in normals."	( Weissel, M, 2001)
"Mitral valve prolapse is a common valvular heart disease with significant complications."	( Bzymek, D; Goddu, B; Han, Y; Kissinger, KV; Manning, WJ; Nezafat, R; Peters, DC; Salton, CJ; Yeon, SB; Zimetbaum, PJ, 2008)
"Mitral valve prolapse is a rare condition and represents a challenge for cardiac surgeons."	( Baldinelli, A; Bettuzzi, MG; Colaneri, M; D'alfonso, A; Pozzi, M; Quarti, A; Ricciotti, R, 2009)
"Mitral valve prolapse is not commonly on the list of differential diagnosis when a patient presents in the emergency department (ED) in severe distress, presenting with non-specific features such as abdominal pain, tachycardia and dyspnea."	( Das, B; Kang, J, 2015)

Excerpt	Reference
"Mitral valve prolapse has been associated with septal to aortic root angle abnormalities determined by echocardiography."	( Arora, RR; Goldman, ME; Horowitz, SF; Machac, J, 1986)
"Most patients with mitral valve prolapse have no symptoms."	( Gopalaswamy, C; Gould, L, 1984)

Excerpt	Reference
"A 32-year-old woman with prolapsed mitral valve was treated with flecainide because of an episode of primary ventricular fibrillation."	( Follath, F; Hoffmann, A; Wenk, M, 1986)
"In the majority of cases, mitral valve prolapse is benign and no specific treatment is needed except reassurance and perhaps endocarditis prophylaxis."	( de Leon, AC, 1980)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	240 (51.28)	23.3326
1990's	79 (16.88)	12.5806
2000's	65 (13.89)	18.1394
2010's	52 (11.11)	28.8240
2020's	32 (6.84)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
hydrochloric acid	low	1	0
cytosine	low	2	0
lactic acid	medium	9	3
indoleacetic acid	low	1	0
iodine	low	1	0
phytic acid	low	1	0
orotic acid	medium	3	1
taurine	low	1	0
thiamine	low	1	0
uric acid	low	1	0
phenytoin	low	1	0
hydroxyindoleacetic acid	low	1	0
acebutolol	low	1	0
alprazolam	medium	2	1
alprenolol	low	1	0
theophylline	low	1	0
amiodarone	low	9	0
amlodipine	low	1	0
aprindine	low	1	0
aspirin	medium	15	1
atenolol	medium	2	1
bupivacaine	low	4	0
caffeine	low	3	0
verapamil	low	9	0
candesartan	low	2	0
carteolol	low	2	0
carvedilol	low	1	0
celiprolol	low	1	0
cimetidine	low	1	0
clomipramine	medium	1	1
clonidine	low	2	0
desipramine	low	1	0
diazepam	medium	2	1
dipyridamole	medium	8	1
disopyramide	medium	3	1
domperidone	low	1	0
edrophonium	low	3	0
enflurane	low	1	0
berotek	low	1	0
fentanyl	low	1	0
flecainide	low	3	0
flucytosine	low	1	0
furosemide	medium	7	1
gentamicin	low	4	0
glutaral	low	1	0
halothane	low	2	0
hexobarbital	low	1	0
hydralazine	low	2	0
phenelzine	medium	2	1
lidocaine	low	4	0
imipramine	medium	9	2
iodixanol	low	1	0
2-propanol	low	1	0
isoproterenol	low	10	0
ketamine	low	2	0
labetalol	medium	1	1
lorazepam	low	1	0
losartan	low	1	0
methylphenidate	low	3	0
metoprolol	low	7	0
mexiletine	medium	2	1
apnea	low	1	0
neostigmine	low	2	0
nitroglycerin	low	5	0
phenobarbital	low	1	0
pimobendan	medium	4	3
pindolol	medium	4	1
prazosin	low	2	0
procainamide	low	3	0
procaine	low	1	0
propafenone	low	4	0
propofol	low	2	0
propranolol	medium	40	7
sotalol	low	1	0
sulfinpyrazone	medium	4	1
sulmazole	medium	1	1
tetraethylammonium	low	1	0
theobromine	low	1	0
ticlopidine	low	1	0
trazodone	low	2	0
reserpine	low	3	0
phentolamine	low	1	0
hydroxyproline	low	1	0
thyroxine	low	1	0
aldosterone	low	6	0
prednisone	low	1	0
penicillin g	low	2	0
triiodothyronine	low	2	0
adenosine diphosphate	low	1	0
galactose	low	1	0
phenylephrine	low	3	0
methoxamine	low	4	0
methacholine chloride	low	1	0
methionine	low	1	0
ampicillin	low	3	0
valine	low	1	0
arginine	low	2	0
isoprene	low	1	0
penicillin v	low	1	0
isosorbide dinitrate	low	1	0
2-methylpentane	low	1	0
n-hexane	low	1	0
chloroprocaine	low	1	0
nafcillin	low	1	0
thiamine pyrophosphate	low	1	0
opipramol	low	1	0
triflusal	low	1	0
n-pentyl nitrite	low	7	0
cyanogen bromide	low	1	0
gluconic acid	medium	1	1
copper gluconate	medium	1	1
methoxyhydroxyphenylglycol	low	2	0
malondialdehyde	low	2	0
magnesium carbonate	medium	1	1
erythromycin stearate	low	1	0
erythromycin	low	6	0
vancomycin	low	3	0
s,n,n'-tripropylthiocarbamate	low	1	0
5-hydroxyindole	low	1	0
flupenthixol	low	1	0
floxacillin	low	1	0
iodinated glycerol	low	1	0
mercury	low	1	0
technetium	low	3	0
gadolinium	low	19	0
magnesium sulfate	low	1	0
trolamine salicylate	low	3	0
trausabun	low	1	0
ammonium chloride	low	1	0
carbimazole	low	1	0
phenyl acetate	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
4-methoxyamphetamine	medium	1	1
adenosine diphosphate ribose	low	1	0
amoxicillin	low	4	0
timolol	low	1	0
moricizine	medium	1	1
dobutamine	medium	4	1
penbutolol	medium	1	1
amikacin	low	1	0
tolamolol	medium	1	1
methyldopa	low	1	0
sq-11725	medium	3	1
diltiazem	low	1	0
sufentanil	low	1	0
lorcainide	medium	1	1
encainide	low	2	0
fomesafen	low	3	0
simvastatin	low	1	0
remifentanil	low	1	0
atorvastatin	low	1	0
3-iodobenzylguanidine	low	3	0
adenosine	low	1	0
cephalosporin c	low	1	0
telmisartan	low	1	0
fluorodeoxyglucose f18	low	2	0
c.i. direct red 80	low	1	0
fibrinogen	low	2	0
vitamin b 6	low	1	0
gilutensin hydrochloride	low	1	0
methotrexate	low	1	0
aspartame	low	1	0
symmetric dimethylarginine	low	1	0
angiotensin ii	low	2	0
atropine	medium	9	1
benzofurans	medium	2	1
fibrin	low	3	0
elastin	low	4	0
inositol 3-phosphate	low	1	0
quinidine	low	6	0
digitoxin	low	3	0
ergonovine	low	2	0
erythromycin ethylsuccinate	low	1	0
cocaine	low	1	0
clindamycin	low	1	0
keratan sulfate	low	1	0
zithromax	low	2	0
riboflavin	low	2	0
propylthiouracil	low	1	0
flunarizine	low	1	0
methimazole	low	1	0
digoxin	medium	11	1
17-iodoheptadecanoic acid	low	1	0
fusidic acid	low	1	0
thiopental	low	1	0
magnesium orotate	medium	3	1
prucalopride	medium	1	1
nitinol	low	1	0
osteoprotegerin	low	1	0
alprostadil	low	2	0
amphotericin b	low	1	0
coenzyme q10	medium	6	3
phenylephrine hydrochloride	low	3	0
morphine	low	1	0
thallium	low	11	0
ramipril	medium	2	1
enalapril	medium	4	1
cysteine	low	1	0
phosphorus	low	2	0
heroin	low	1	0
cefotaxime	low	1	0
ajmaline	low	2	0
gadolinium dtpa	low	2	0
dimethylarginine	low	1	0
td-5108	medium	1	1
desmosine	low	1	0
cytochrome c-t	low	1	0
cosyntropin	medium	1	1
atrial natriuretic factor	low	5	0
beta-endorphin	medium	1	1
neuropeptide y	low	1	0
angiotensinogen	low	3	0
ubiquinone	medium	6	3
technetium tc 99m sestamibi	low	1	0
sodium glutamate	low	1	0
ro13-9904	low	2	0
sodium pertechnetate tc 99m	low	2	0
sodium ethylxanthate	low	1	0
cardiovascular agents	medium	2	1
fibrinopeptide a	low	1	0
piperidines	medium	3	1
eliglustat tartrate	low	1	0
natriuretic peptide, brain	low	2	0
heme	low	1	0
ascorbic acid	low	1	0
minocycline	low	1	0
salicylates	low	1	0
dicumarol	medium	1	1
warfarin	low	14	0
transforming growth factor beta	low	12	0
rome	low	2	0
cyclic gmp	low	2	0
sapropterin	low	1	0
rifampin	low	1	0
guanylyl imidodiphosphate	low	1	0
eye	low	4	0
leptin	low	1	0

Protein Targets (1,369)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
retinoic acid nuclear receptor alpha variant 1	40	0	0	40
retinoid X nuclear receptor alpha	31	0	0	31
estrogen-related nuclear receptor alpha	54	0	0	54
pregnane X nuclear receptor	42	0	0	42
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
RAR-related orphan receptor gamma	39	0	0	39
GLI family zinc finger 3	48	0	0	48
AR protein	64	0	0	64
aldehyde dehydrogenase 1 family, member A1	33	0	0	33
estrogen nuclear receptor alpha	72	0	0	72
peroxisome proliferator-activated receptor delta	22	0	0	22
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	24	0	0	24
activating transcription factor 6	24	0	0	24
v-jun sarcoma virus 17 oncogene homolog (avian)	27	0	0	27
Histone H2A.x	20	0	0	20
thyroid hormone receptor beta isoform a	16	0	0	16
heat shock protein beta-1	15	0	0	15
nuclear factor erythroid 2-related factor 2 isoform 1	42	0	0	42
lamin isoform A-delta10	61	0	0	61
Voltage-dependent calcium channel gamma-2 subunit	17	0	0	17
Glutamate receptor 2	17	0	0	17
dopamine D1 receptor	7	0	0	7
thioredoxin reductase	40	0	0	40
GLS protein	28	0	0	28
Thrombopoietin	7	0	0	7
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
cytochrome P450 2D6 isoform 1	15	0	0	15
cytochrome P450 2C19 precursor	12	0	0	12
ras-related protein Rab-9A	8	0	0	8
histone acetyltransferase KAT2A isoform 1	21	0	0	21
lethal factor (plasmid)	15	0	0	15
POU domain, class 2, transcription factor 1	0	0	0	5
Spike glycoprotein	31	0	1	32
ATP-dependent phosphofructokinase	34	0	0	34
5-hydroxytryptamine receptor 2C	0	12	1	14
5-hydroxytryptamine receptor 2A	0	12	1	13
5-hydroxytryptamine receptor 1A	0	41	6	48
5-hydroxytryptamine receptor 1B	0	29	1	30
5-hydroxytryptamine receptor 1D	0	8	1	9
5-hydroxytryptamine receptor 1F	0	8	1	9
5-hydroxytryptamine receptor 2B	0	10	1	11
5-hydroxytryptamine receptor 6	0	4	1	5
Sodium-dependent serotonin transporter	0	26	1	27
Sodium-dependent serotonin transporter	0	10	1	12
5-hydroxytryptamine receptor 7	0	4	1	5
5-hydroxytryptamine receptor 5A	0	4	1	5
5-hydroxytryptamine receptor 5B	0	4	1	5
5-hydroxytryptamine receptor 3A	0	5	1	6
5-hydroxytryptamine receptor 4	0	4	2	6
5-hydroxytryptamine receptor 3B	0	5	1	6
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
15-lipoxygenase, partial	7	0	0	7
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
ATAD5 protein, partial	20	0	0	20
TDP1 protein	56	0	0	56
lysosomal alpha-glucosidase preproprotein	7	0	0	7
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
heat shock protein HSP 90-alpha isoform 2	0	2	0	2
geminin	51	0	0	51
neuropeptide S receptor isoform A	7	0	0	7
DNA repair and recombination protein RadA	0	0	1	1
Leukotriene A-4 hydrolase	0	1	0	1
Tyrosinase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	0	1	1
Sulfotransferase 1E1	0	0	0	1
Sulfotransferase 1A1	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	6	0	0	6
DNA repair protein RAD51 homolog 1	0	0	1	1
large T antigen	0	2	0	2
Solute carrier family 22 member 1	0	28	0	35
Beta-2 adrenergic receptor	0	25	14	40
Beta-1 adrenergic receptor	0	29	12	41
Beta-3 adrenergic receptor	0	17	12	29
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	28	0	0	28
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear receptor subfamily 1, group I, member 3	35	0	0	35
cytochrome P450 family 3 subfamily A polypeptide 4	46	0	0	46
glucocorticoid receptor [Homo sapiens]	47	0	0	47
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	14
importin subunit beta-1 isoform 1	8	0	0	8
snurportin-1	8	0	0	8
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
Bile salt export pump	0	80	0	80
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	9	0	0	9
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	13	0	0	13
Ataxin-2	31	0	0	31
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	26	0	0	26
NPYLR7B	0	0	4	4
arylsulfatase A	25	0	0	25
IDH1	21	0	0	21
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	16	0	0	16
flap endonuclease 1	10	0	0	10
nuclear receptor ROR-gamma isoform 1	19	0	0	19
peripheral myelin protein 22	27	0	0	27
survival motor neuron protein isoform d	11	0	0	11
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	7	0	0	7
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	5	0	5
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	3	0	3
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	2	5
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	11	3	15
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	7	1	10
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	6	6	15
Adenosine receptor A2b	0	2	1	6
Adenosine receptor A2b	0	5	2	9
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	7	4	16
Adenosine receptor A2a	0	7	3	14
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	3	1	4
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	4	0	4
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	13	5	19
Delta-type opioid receptor	0	7	3	11
Kappa-type opioid receptor	0	9	3	13
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	9	0	0	9
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	0	1	1
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	1	2	3
Androgen receptor	0	3	0	3
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	4
Guanine nucleotide-binding protein G	6	0	0	6
peroxisome proliferator activated receptor gamma	39	0	0	39
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	14	0	0	14
thyroid hormone receptor beta isoform 2	45	0	0	45
Gamma-aminobutyric acid receptor subunit pi	26	7	7	40
Bromodomain-containing protein 4	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	7	4	11
Gamma-aminobutyric acid receptor subunit beta-1	26	7	7	40
Gamma-aminobutyric acid receptor subunit delta	26	7	7	40
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	2	9
Gamma-aminobutyric acid receptor subunit gamma-2	26	7	7	40
Gamma-aminobutyric acid receptor subunit alpha-5	26	7	7	40
Gamma-aminobutyric acid receptor subunit alpha-3	26	7	7	40
Gamma-aminobutyric acid receptor subunit gamma-1	26	7	7	40
Gamma-aminobutyric acid receptor subunit alpha-2	26	7	7	40
Gamma-aminobutyric acid receptor subunit alpha-4	26	7	7	40
Gamma-aminobutyric acid receptor subunit gamma-3	26	7	7	40
Gamma-aminobutyric acid receptor subunit alpha-6	26	7	7	40
Cholecystokinin receptor type A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	6	4	10
Gamma-aminobutyric acid receptor subunit alpha-3	0	6	3	9
Gamma-aminobutyric acid receptor subunit alpha-2	0	6	3	9
Gamma-aminobutyric acid receptor subunit beta-2	0	6	2	8
Gamma-aminobutyric acid receptor subunit alpha-1	26	8	7	41
Gamma-aminobutyric acid receptor subunit beta-3	26	7	7	40
Gamma-aminobutyric acid receptor subunit beta-2	26	7	7	40
Cholecystokinin receptor type A	0	1	0	1
GABA theta subunit	26	7	7	40
Gamma-aminobutyric acid receptor subunit epsilon	26	7	7	40
cytochrome P450 2D6	37	0	0	37
euchromatic histone-lysine N-methyltransferase 2	58	0	0	58
D(1A) dopamine receptor	23	0	0	23
DNA polymerase kappa isoform 1	16	0	0	16
ATP-binding cassette sub-family C member 3	0	52	0	52
Multidrug resistance-associated protein 4	0	52	0	55
5-hydroxytryptamine receptor 1A	0	9	3	12
Alpha-2A adrenergic receptor	0	30	6	41
Beta-2 adrenergic receptor	0	4	1	8
Cytochrome P450 2C9	0	27	0	27
Alpha-2B adrenergic receptor	0	28	4	37
Beta-1 adrenergic receptor	0	7	3	14
Alpha-2C adrenergic receptor	0	23	5	33
Alpha-1D adrenergic receptor	0	24	6	36
Alpha-1A adrenergic receptor	0	9	8	25
Alpha-1B adrenergic receptor	0	8	7	21
Cytochrome P450 2J2	0	20	0	20
Squalene synthase	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	49	0	49
Cellular tumor antigen p53	39	0	0	39
Thromboxane-A synthase	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
acetylcholinesterase	18	0	0	18
phosphopantetheinyl transferase	18	0	0	18
SMAD family member 2	11	0	0	11
Fumarate hydratase	12	0	0	12
USP1 protein, partial	26	0	0	26
NFKB1 protein, partial	11	0	0	11
PPM1D protein	6	0	0	6
SMAD family member 3	11	0	0	11
caspase 7, apoptosis-related cysteine protease	7	0	0	7
thyroid stimulating hormone receptor	23	0	0	23
estrogen receptor 2 (ER beta)	25	0	0	25
progesterone receptor	25	0	0	25
EWS/FLI fusion protein	33	0	0	33
farnesoid X nuclear receptor	27	0	0	27
G	24	0	0	24
polyprotein	12	0	0	12
caspase-3	7	0	0	7
thyroid stimulating hormone receptor	19	0	0	19
cellular tumor antigen p53 isoform a	10	0	0	10
cytochrome P450 2C9 precursor	9	0	0	9
chromobox protein homolog 1	36	0	0	36
potassium voltage-gated channel subfamily H member 2 isoform d	25	0	0	25
huntingtin isoform 2	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	14	0	0	14
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
cytochrome P450 3A4 isoform 1	26	0	0	26
muscarinic acetylcholine receptor M1	25	0	0	25
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	0	0	10
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	8
Solute carrier organic anion transporter family member 1A4	0	5	0	8
Voltage-dependent L-type calcium channel subunit alpha-1F	0	12	0	12
5-hydroxytryptamine receptor 4	0	27	1	28
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	31	0	0	31
HLA class I histocompatibility antigen, B alpha chain	24	0	0	24
Thyroid hormone receptor alpha	0	1	0	1
Integrin beta-3	8	1	0	9
Tyrosine-protein kinase Fyn	0	3	0	3
ATP-dependent translocase ABCB1	0	10	0	10
Aldo-keto reductase family 1 member B1	0	20	0	20
Muscarinic acetylcholine receptor M2	0	7	2	12
Muscarinic acetylcholine receptor M4	0	8	1	11
ATP-dependent translocase ABCB1	0	29	3	46
Integrin alpha-IIb	8	1	0	9
Muscarinic acetylcholine receptor M5	0	8	1	11
Cytochrome P450 2C8	0	5	0	5
Thyroid hormone receptor alpha	0	3	3	6
Thyroid hormone receptor beta	0	3	3	6
Muscarinic acetylcholine receptor M1	0	9	2	14
D(2) dopamine receptor	0	18	1	19
Alpha-1B adrenergic receptor	0	21	4	25
Lethal factor	0	1	0	1
Thyroid hormone receptor beta	0	3	0	3
Muscarinic acetylcholine receptor M3	0	9	2	13
ATP-dependent translocase ABCB1	0	10	0	11
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	12	1	13
D(4) dopamine receptor	0	5	0	5
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	28	1	29
Histamine H2 receptor	0	8	0	8
Endothelin-1 receptor	0	3	1	4
5-hydroxytryptamine receptor 2A	0	27	1	28
5-hydroxytryptamine receptor 2C	0	29	1	30
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	2	0	2
Melanocortin receptor 5	0	2	0	2
D(3) dopamine receptor	0	21	0	21
Sodium channel protein type 1 subunit alpha	0	6	0	6
Sodium channel protein type 4 subunit alpha	0	7	0	8
Squalene synthase	0	1	0	1
5-hydroxytryptamine receptor 2B	0	31	1	32
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	22	5	27
Histamine H2 receptor	15	5	2	24
D(1A) dopamine receptor	11	0	0	11
5-hydroxytryptamine receptor 6	0	15	1	16
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	12	0	12
Sodium-dependent dopamine transporter	0	23	0	23
Potassium voltage-gated channel subfamily H member 2	0	30	0	30
Voltage-dependent L-type calcium channel subunit alpha-1S	0	12	0	12
Voltage-dependent L-type calcium channel subunit alpha-1C	0	15	0	15
Sodium channel protein type 5 subunit alpha	0	12	0	12
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	7	0	7
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	24	0	0	24
Sodium channel protein type 2 subunit alpha	0	6	0	6
Sigma non-opioid intracellular receptor 1	0	25	1	26
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	7	0	7
Sodium channel protein type 11 subunit alpha	0	4	0	4
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	4	0	4
Sodium channel protein type 10 subunit alpha	0	4	0	4
cytochrome P450 2C9, partial	24	0	0	24
Chain A, Ferritin light chain	9	0	0	9
acid sphingomyelinase	5	0	0	5
Smad3	9	0	0	9
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
Potassium channel subfamily K member 2	0	5	5	10
Alpha-2B adrenergic receptor	0	14	6	20
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Alpha-2C adrenergic receptor	0	14	6	20
Alpha-2A adrenergic receptor	0	14	6	20
Potassium channel subfamily K member 2	0	2	0	2
Chain A, Beta-lactamase	16	0	0	16
Chain A, 2-oxoglutarate Oxygenase	18	0	0	18
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	3
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	16	0	0	16
Bile salt export pump	0	14	0	14
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase	0	0	0	3
Kappa-type opioid receptor	0	5	0	8
Solute carrier family 15 member 1	0	10	0	10
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Chain A, HADH2 protein	16	0	0	16
Chain B, HADH2 protein	16	0	0	16
Chain A, Cruzipain	10	0	0	10
interleukin 8	11	0	0	11
vitamin D (1,25- dihydroxyvitamin D3) receptor	32	0	0	32
tumor necrosis factor	3	0	0	3
vitamin D3 receptor isoform VDRA	14	0	0	14
Cytochrome P450 1A2	0	3	0	4
Cytochrome P450 3A4	0	14	2	19
Cytochrome P450 2D6	0	14	0	14
Cytochrome P450 2C19	0	5	0	6
Nuclear receptor ROR-gamma	8	1	1	10
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	12	1	15
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	0	3
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
DNA polymerase beta	6	0	0	6
Carbonic anhydrase 1	0	10	0	11
Carbonic anhydrase 2	0	10	1	12
60 kDa heat shock protein, mitochondrial	0	6	0	6
Beta-lactamase OXA-7	0	0	0	2
10 kDa heat shock protein, mitochondrial	0	6	0	6
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Thiosulfate sulfurtransferase	0	6	0	6
Metallo-beta-lactamase VIM-13	0	0	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	3
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	6	0	6
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	6	0	6
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	3
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	0	0	3
glucocerebrosidase	7	0	0	7
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1A angiotensin II receptor	0	4	3	7
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	8	4	16
Type-2 angiotensin II receptor	0	5	0	5
Type-2 angiotensin II receptor	0	5	0	5
Microtubule-associated protein tau	18	0	0	18
Bloom syndrome protein isoform 1	12	0	0	12
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
alpha-galactosidase	8	0	0	8
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	1	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	6	0	0	6
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Polyphenol oxidase 2	0	3	0	4
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	3	0	3
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
aryl hydrocarbon receptor	17	0	0	17
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	3	0	0	3
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	7	0	7
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Fatty acid-binding protein, liver	0	5	0	5
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	1	3
Beta-1 adrenergic receptor	0	1	7	10
Beta-2 adrenergic receptor	0	3	8	12
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
Solute carrier organic anion transporter family member 2B1	0	2	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Histone deacetylase 1	0	1	0	1
Histone deacetylase 2	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	9	0	13
Histone deacetylase 6	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	13	0	17
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	2	2
Muscarinic acetylcholine receptor M1	0	4	1	7
Muscarinic acetylcholine receptor M3	0	3	1	6
Muscarinic acetylcholine receptor M4	0	3	1	6
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M2	0	3	1	7
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 7	0	13	0	14
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
glp-1 receptor, partial	15	0	0	15
beta-2 adrenergic receptor	3	0	0	3
Potassium channel subfamily K member 3	0	4	0	4
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Cholinesterase	0	6	0	6
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Replicase polyprotein 1ab	0	5	1	6
Amine oxidase [flavin-containing] A	0	5	0	5
Acetylcholinesterase	0	6	0	6
Amine oxidase [flavin-containing] B	0	6	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	6	0	6
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	2	0	2
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	2	0	2
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	2	0	2
60 kDa chaperonin	0	3	0	3
Type-1 angiotensin II receptor	0	3	1	4
Leukotriene B4 receptor 2	0	1	1	2
Lactoperoxidase	0	2	0	2
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Toll-like receptor 4	0	2	0	2
Solute carrier family 22 member 2	0	11	0	13
Amyloid-beta precursor protein	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	3	1	0	4
Neuronal acetylcholine receptor subunit beta-2	3	1	0	4
Angiotensin-converting enzyme	0	12	0	12
UDP-glucuronosyltransferase 1A1	0	3	0	3
Potassium channel subfamily K member 10	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	10	0	10
Multidrug and toxin extrusion protein 1	0	15	0	15
Solute carrier family 22 member 6	0	3	0	5
Solute carrier family 22 member 7	0	2	0	2
Solute carrier family 22 member 8	0	6	0	8
Solute carrier family 22 member 11	0	3	0	4
Solute carrier family 22 member 8	0	5	0	6
Solute carrier family 22 member 7	0	2	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	2
Albumin	0	3	11	15
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
67.9K protein	6	0	0	6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
thyrotropin-releasing hormone receptor	5	0	0	5
Caspase-2	0	0	1	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	15	0	0	15
streptokinase A precursor	0	0	6	6
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
50S ribosomal protein L36 2	0	3	1	4
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase 4	0	4	0	5
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 15	0	2	0	2
M-phase phosphoprotein 8	8	0	0	8
Solute carrier family 22 member 1	0	4	0	5
Solute carrier family 22 member 2	0	3	0	4
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Histamine H1 receptor	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	1	0	1
Solute carrier family 22 member 1	0	14	0	16
Multidrug and toxin extrusion protein 2	0	6	0	6
Histamine H4 receptor	0	1	0	1
Solute carrier family 22 member 2	0	11	0	12
Solute carrier family 22 member 4	0	4	0	4
Protein-arginine deiminase type-4	0	5	0	5
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
atrial natriuretic peptide receptor 2 precursor	6	0	0	6
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Alpha-1D adrenergic receptor	0	14	4	19
Trypanothione reductase	0	2	0	2
Histamine H1 receptor	0	3	0	3
Histamine H1 receptor	0	12	0	12
Trypanothione reductase	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	1
D(2) dopamine receptor	0	9	0	10
Voltage-dependent N-type calcium channel subunit alpha-1B	0	5	0	5
Envelope glycoprotein	0	0	2	2
Angiotensin-converting enzyme 2	0	1	1	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	3	0	0	3
Alpha-1B adrenergic receptor	0	0	2	2
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	8	0	8
Alpha-1A adrenergic receptor	0	3	2	5
D	0	4	0	5
D(3) dopamine receptor	0	4	0	4
D(1B) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	3
D(4) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	6	0	7
Mu-type opioid receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	2	0	2
Nischarin	0	2	0	2
Nischarin	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	5	0	5
Gamma-aminobutyric acid receptor subunit delta	0	5	0	5
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	1	2
Tryptophan 5-hydroxylase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	5	1	6
Liver carboxylesterase 1	0	0	0	2
Sodium-dependent dopamine transporter	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	6	2	8
Glutamate receptor ionotropic, NMDA 1	0	4	1	5
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	1	6
Gamma-aminobutyric acid receptor subunit epsilon	0	5	0	5
Glutamate receptor ionotropic, NMDA 2A	0	4	1	5
Glutamate receptor ionotropic, NMDA 2B	0	4	1	5
Glutamate receptor ionotropic, NMDA 2C	0	4	1	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	5	1	6
Sodium-dependent dopamine transporter	0	3	0	3
Glutamate receptor ionotropic, NMDA 2D	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	5	0	5
Glutamate receptor ionotropic, NMDA 3B	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-3	0	5	0	5
Glutamate receptor ionotropic, NMDA 3A	0	4	1	5
Gamma-aminobutyric acid receptor subunit theta	0	5	0	5
Transporter	0	7	0	7
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	2	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	5	0	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	5	0	5
Deoxycytidine kinase	0	0	0	1
Solute carrier family 22 member 3	0	1	0	2
Histamine H3 receptor	0	1	0	1
Histamine H3 receptor	0	1	0	1
Gamma-aminobutyric acid	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	0	3	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	4
Translocator protein	0	1	2	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Translocator protein	0	1	0	1
Translocator protein	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Luciferase	12	0	0	12
NAD	0	1	0	1
NAD	0	1	0	2
Mitogen-activated protein kinase 1	0	1	0	1
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Integrase	0	1	0	1
G-protein coupled receptor 35	0	2	2	4
STAT3, partial	0	2	0	2
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-3	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-3	0	2	0	2
Sodium/potassium-transporting ATPase subunit gamma	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-4	0	2	0	2
Solute carrier organic anion transporter family member 4C1	0	2	0	4
PAX8	0	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	2
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	3	0	3
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
RGS12	1	0	0	1
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	2	0	0	2
nonstructural protein 1	5	0	0	5
LANA	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
peripheral myelin protein 22 isoform 1	8	0	0	8
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
serine/threonine-protein kinase PLK1	5	0	0	5
eyes absent homolog 2 isoform a	2	0	0	2
muscleblind-like protein 1 isoform 1	5	0	0	5
caspase-1 isoform alpha precursor	4	0	0	4
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	7	0	7
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	3	0	3
Caspase-7	4	0	0	4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	4	0	4
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
Exopolyphosphatase PRUNE1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Single-stranded DNA cytosine deaminase	3	0	0	3
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
GALC protein	6	0	0	6
mu-type opioid receptor isoform MOR-1	0	0	2	2
5-hydroxytryptamine receptor 2A	0	0	2	2
Carbonic anhydrase 12	0	2	0	3
Tyrosine-protein kinase Lck	0	1	0	1
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase 6	0	4	0	5
Carbonic anhydrase 5A, mitochondrial	0	3	0	4
Carbonic anhydrase 7	0	3	0	4
Carbonic anhydrase 9	0	3	0	4
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 14	0	2	0	3
Carbonic anhydrase 5B, mitochondrial	0	3	0	4
Retinoic acid receptor RXR-alpha	0	0	3	3
Acetylcholinesterase	0	1	0	1
endonuclease IV	6	0	0	6
Angiotensin-converting enzyme	0	4	0	4
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Lanosterol 14-alpha demethylase	0	5	0	5
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Delta-type opioid receptor	0	7	1	9
Mu-type opioid receptor	0	9	2	14
Kappa-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	3	1	6
Sigma non-opioid intracellular receptor 1	0	6	1	7
Potassium voltage-gated channel subfamily A member 5	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	3	0	3
Skn7p	0	0	0	1
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sodium channel protein type 3 subunit alpha	0	3	0	3
Cannabinoid receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	0	1	1
Prostaglandin D2 receptor 2	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Carbonic anhydrase 13	0	2	0	3
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Chain A, Type Iii Chloramphenicol Acetyltransferase	0	1	0	1
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
Canalicular multispecific organic anion transporter 1	0	2	0	3
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
Parkin	4	0	0	4
pyruvate kinase	2	0	0	2
pyruvate kinase PKM isoform b	1	0	0	1
N-glycosylase/DNA lyase	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Amino acid transporter	0	1	0	1
Snq2p	0	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Major prion protein	0	0	1	1
Sphingomyelin phosphodiesterase	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	2
D(2) dopamine receptor	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Peptide deformylase 1A, chloroplastic/mitochondrial	0	1	0	1
Peptide deformylase	0	1	0	1
histone deacetylase 9 isoform 3	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	3	1	4
Beta-2 adrenergic receptor	0	3	0	3
Taste receptor type 2 member 38	0	0	2	3
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	2	3
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Acetylcholinesterase	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Cholinesterase	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Heparanase	0	0	1	1
Potassium channel subfamily K member 18	0	1	0	1
Neprilysin	0	1	0	1
Thromboxane A2 receptor	0	1	0	3
Platelet glycoprotein VI	0	1	1	3
Type-1 angiotensin II receptor	0	1	1	2
galanin receptor type 3	0	1	0	1
Dopamine beta-hydroxylase	0	2	0	2
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
transcriptional regulator ERG isoform 3	5	0	0	5
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	2	1	5
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Solute carrier organic anion transporter family member 1A3	0	0	0	3
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
estrogen receptor beta isoform 1	0	2	0	2
Cystathionine gamma-lyase	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Stromelysin-1	0	1	0	1
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Solute carrier family 22 member 8	0	3	0	4
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 9	0	2	2	4
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Membrane primary amine oxidase	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Hsf1 protein	0	0	1	1
Alpha-1A adrenergic receptor	0	1	2	3
Alpha-1B adrenergic receptor	0	3	0	3
Vpr	1	0	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
5-hydroxytryptamine receptor 1B	0	4	1	5
interferon gamma precursor	0	0	0	1
Beta-casein	0	1	0	1
Interstitial collagenase	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
5-hydroxytryptamine receptor 1D	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
pregnane X receptor	2	0	0	2
Glucocorticoid receptor	0	2	1	3
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Sterol O-acyltransferase 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
ATP-binding cassette sub-family C member 9	0	1	0	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	3	3
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Fatty-acid amide hydrolase 1	0	2	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	2	4
Histidine-rich protein PFHRP-II	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Multidrug resistance protein 1a	0	0	0	1
hemoglobin subunit beta	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
Riboflavin-binding protein	0	1	1	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Alpha-synuclein	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	3
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Amine oxidase [flavin-containing] A	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Glycine receptor subunit alpha-1	0	0	1	1
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	5	6
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor delta	0	1	1	2
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Solute carrier family 22 member 3	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	1	2
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Transthyretin	0	1	0	3
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Prothrombin	0	0	1	1
Androgen receptor	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Glycoprotein	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (468)

Protein Targets (1,369)

Click-Murmur Syndrome

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (468)

Drugs Studied (265)

Protein Targets (1,369)