pirbenicillin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

pirbenicillin: RN given refers to (2S-(2 alpha,5 alpha,6 beta))-isomer; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	9871712
CHEMBL ID	2110979
SCHEMBL ID	305647
MeSH ID	M0059563

Synonyms (11)

Synonym
pirbenicillin
8ary01xryu ,
55975-92-3
unii-8ary01xryu
pirbenicillin [inn]
SCHEMBL305647
CHEMBL2110979
DTXSID70204553
(2s,5r,6r)-6-[[(2r)-2-[[2-[[amino(pyridin-4-yl)methylidene]amino]acetyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
gtpl10845
Q27270119

Research Excerpts

Pharmacokinetics

Excerpt	Reference	Relevance
" The pharmacokinetic behavior of pirbenicillin and the other penicillins was analyzed by the two-compartment open model."	( Pirbenicillin: pharmacokinetic parameters in mice. English, AR; Girard, D; Retsema, JA, 1976)	0.26

Dosage Studied

Excerpt	Relevance	Reference
" A minor adjustment in dosage schedule is necessary in reduced renal function."	( Pharmacokinetics of the new broad spectrum penicillin CP-33994-2. Bergan, T; Brodwall, EK; Orjavik, O, 1980)	0.26

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
ampicillin Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.. ampicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.	1.95	1	beta-lactam antibiotic; penicillin allergen; penicillin	antibacterial drug
penicillanic acid Penicillanic Acid: A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed). penicillanic acid : A penam that consists of 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane bearing a carboxy group at position 2 and having (2S,5R)-configuration.	1.95	1	penicillanic acids
carbenicillin Carbenicillin: Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.. carbenicillin : A penicillin antibiotic having a 6beta-2-carboxy-2-phenylacetamido side-chain.	2.35	2	penicillin allergen; penicillin	antibacterial drug
ticarcillin Ticarcillin: An antibiotic derived from penicillin similar to CARBENICILLIN in action.. ticarcillin : A penicillin compound having a 6beta-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group.	1.95	1	penicillin allergen; penicillin	antibacterial drug
blp 1654 BLP 1654: RN given refers to (2S-(2alpha,5alpha,6beta(S*))-isomer; structure	1.95	1

Condition	Relationship Strength	Studies
Kidney Diseases Pathological processes of the KIDNEY or its component tissues.	1.95	1
Bacterial Disease [description not available]	1.95	1
Bacterial Infections Infections by bacteria, general or unspecified.	1.95	1

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