Compounds > pirbenicillin
Page last updated: 2024-12-11

pirbenicillin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

pirbenicillin: RN given refers to (2S-(2 alpha,5 alpha,6 beta))-isomer; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9871712
CHEMBL ID2110979
SCHEMBL ID305647
MeSH IDM0059563

Synonyms (11)

Synonym
pirbenicillin
8ary01xryu ,
55975-92-3
unii-8ary01xryu
pirbenicillin [inn]
SCHEMBL305647
CHEMBL2110979
DTXSID70204553
(2s,5r,6r)-6-[[(2r)-2-[[2-[[amino(pyridin-4-yl)methylidene]amino]acetyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
gtpl10845
Q27270119

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The pharmacokinetic behavior of pirbenicillin and the other penicillins was analyzed by the two-compartment open model."( Pirbenicillin: pharmacokinetic parameters in mice.
English, AR; Girard, D; Retsema, JA, 1976)		0.26

Dosage Studied

ExcerptRelevanceReference
" A minor adjustment in dosage schedule is necessary in reduced renal function."( Pharmacokinetics of the new broad spectrum penicillin CP-33994-2.
Bergan, T; Brodwall, EK; Orjavik, O, 1980)		0.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ampicillin
Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.. ampicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.		1.9510beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
penicillanic acid
Penicillanic Acid: A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed). penicillanic acid : A penam that consists of 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane bearing a carboxy group at position 2 and having (2S,5R)-configuration.		1.9510penicillanic acids
carbenicillin
Carbenicillin: Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.. carbenicillin : A penicillin antibiotic having a 6beta-2-carboxy-2-phenylacetamido side-chain.		2.3520penicillin allergen;
penicillin		antibacterial drug
ticarcillin
Ticarcillin: An antibiotic derived from penicillin similar to CARBENICILLIN in action.. ticarcillin : A penicillin compound having a 6beta-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group.		1.9510penicillin allergen;
penicillin		antibacterial drug
blp 1654
BLP 1654: RN given refers to (2S-(2alpha,5alpha,6beta(S*))-isomer; structure		1.9510
ConditionIndicatedRelationship StrengthStudiesTrials
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues.		01.9510
Bacterial Disease
[description not available]		01.9510
Bacterial Infections
Infections by bacteria, general or unspecified.		01.9510