Noonan Syndrome

A genetically heterogeneous, multifaceted disorder characterized by short stature, webbed neck, ptosis, skeletal malformations, hypertelorism, hormonal imbalance, CRYPTORCHIDISM, multiple cardiac abnormalities (most commonly including PULMONARY VALVE STENOSIS), and some degree of INTELLECTUAL DISABILITY. The phenotype bears similarities to that of TURNER SYNDROME that occurs only in females and has its basis in a 45, X karyotype abnormality. Noonan syndrome occurs in both males and females with a normal karyotype (46,XX and 46,XY). Mutations in a several genes (PTPN11, KRAS, SOS1, NF1 and RAF1) have been associated the NS phenotype. Mutations in PTPN11 are the most common. LEOPARD SYNDROME, a disorder that has clinical features overlapping those of Noonan Syndrome, is also due to mutations in PTPN11. In addition, there is overlap with the syndrome called neurofibromatosis-Noonan syndrome due to mutations in NF1.

Synonym
Noonan Syndrome

Excerpt	Reference
"Noonan syndrome is characterised by a Turner-like phenotype and a normal karyotype."	( Cantez, S; Cefle, K; Erten, NB; Falay, O; Güler, K; Karan, MA; Oztürk, S; Palanduz, S; Tasçioglu, C; Umman, S; Vatansever, S, 2000)
"Noonan syndrome is a developmental disorder with dysmorphic facies, short stature, cardiac defects, and skeletal anomalies, which can be caused by missense PTPN11 mutations."	( Fragale, A; Gelb, BD; Tartaglia, M; Wu, J, 2004)
"Although Noonan syndrome is quite prevalent, there is a general paucity in the description of psychological and psychiatric aspects."	( Egger, JI; Hendrikx, JL; MDoorakkers, MC; Tuinier, S; Van der Burgt, I; Verhoeven, WM, 2004)
"Noonan syndrome is a well-known clinical entity comprising multiple congenital anomalies characterized by typical facial features, short stature and congenital heart defect."	( Jongmans, M; Noordam, K; Otten, B; van der Burgt, I, 2004)
"Noonan syndrome is a relatively uncommon genetic disorder with implications for anesthesia due to multiple organ system involvement."	( Campbell, DC; Lemire, EG; McBain, J, 2006)
"Turner syndrome and Noonan syndrome are clinically defined conditions associated with short stature."	( Chacko, EM; Rapaport, R, 2012)
"Noonan syndrome is an autosomal dominant developmental disorder."	( Akagi, E; Hamada, A; Koizumi, K; Nakanishi, M; Nishimura, K; Obayashi, F; Ohtaka, M; Okamoto, T; Toratani, S; Yamasaki, S, 2020)
"Noonan syndrome is a multiorgan system disorder mediated by genetic defects along the RASknown as RASopathies."	( Belasco, J; Dori, Y; Hakonarson, H; March, ME; Pinto, E; Smith, C; Snyder, K, 2020)

Excerpt	Reference
"Noonan syndrome has been diagnosed by the characteristic physical stigmata for more than two decades."	( Itabashi, H; Kuramochi, K; Naito, T; Sato, A; Takemura, Y; Tanaka, K, 1992)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	19 (13.57)	23.3326
1990's	15 (10.71)	12.5806
2000's	40 (28.57)	18.1394
2010's	38 (27.14)	28.8240
2020's	28 (20.00)	9.53

Drug	Relationship Strength	Studies	Trials
phosphoserine	low	1	0
adenine	low	1	0
carnitine	low	1	0
salicylic acid	low	3	0
cytosine	low	1	0
nitrous oxide	low	1	0
thymine	low	1	0
vanilmandelic acid	low	1	0
homovanillic acid	low	1	0
acetazolamide	low	1	0
amiodarone	low	2	0
amitriptyline	low	1	0
aspirin	low	1	0
atenolol	low	1	0
verapamil	medium	1	1
cifenline	low	1	0
citalopram	low	1	0
dapi	low	1	0
dipyridamole	low	1	0
domperidone	low	1	0
berotek	low	1	0
fentanyl	low	2	0
flecainide	low	1	0
furosemide	low	1	0
gabapentin	low	1	0
lidocaine	low	1	0
ifosfamide	low	1	0
iohexol	low	1	0
iopromide	low	1	0
isoflurane	low	1	0
2-propanol	low	6	0
khellin	low	2	0
phenindione	low	1	0
prilocaine	low	1	0
primidone	low	1	0
propofol	low	1	0
propranolol	medium	6	1
sevoflurane	low	1	0
sulfamethoxazole	low	1	0
terbutaline	low	1	0
trimethoprim	low	1	0
thyroxine	low	2	0
spironolactone	low	1	0
prednisone	low	1	0
oxandrolone	low	2	0
androsterone	low	1	0
etiocholanolone	low	1	0
triiodothyronine	low	1	0
serine	low	2	0
glutamine	low	1	0
adenosine diphosphate	low	1	0
tyrosine	low	1	0
ampicillin	low	1	0
mestranol	low	1	0
isoleucine	low	1	0
arginine	low	1	0
fluoxymesterone	low	1	0
methylprednisolone	low	1	0
quinazolines	low	1	0
ephedrine	low	1	0
azacitidine	low	1	0
myristic acid	low	1	0
enbucrilate	low	1	0
technetium	low	1	0
argon	low	1	0
barium sulfate	low	1	0
trolamine salicylate	low	1	0
triamcinolone	low	1	0
glutamic acid	low	1	0
etoposide	low	1	0
lovastatin	low	2	0
remifentanil	low	1	0
zoledronic acid	low	1	0
fluindione	low	1	0
pyridinoline	low	2	0
deoxypyridinoline	low	2	0
imatinib mesylate	low	1	0
galactosylhydroxylysine	low	1	0
technetium tc 99m pentetate	low	1	0
ropivacaine	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
fibrin	low	1	0
dactinomycin	low	1	0
isomethyleugenol	low	1	0
enclomiphene	low	1	0
digoxin	low	1	0
u 0126	low	2	0
hydroxylysine	low	1	0
17-ketosteroids	low	1	0
calcitriol	low	1	0
acitretin	low	1	0
sirolimus	low	2	0
deamino arginine vasopressin	low	2	0
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid	low	1	0
antimony	low	1	0
phosphorus	low	1	0
pd 184352	low	1	0
cediranib	low	1	0
azd 6244	low	1	0
trametinib	low	6	0
felypressin	low	1	0
jaw	low	4	0
cytochrome c-t	low	1	0
glucagon	low	1	0
cardiovascular agents	low	2	0
piperidines	low	1	0
natriuretic peptide, brain	low	2	0
warfarin	low	2	0
epidermal growth factor	low	2	0
cyclin d1	low	1	0
technetium tc 99m sulfur colloid	low	2	0
vitamin b 12	low	1	0
cyclosporine	low	1	0
technetium tc 99m medronate	low	1	0
thromboplastin	low	1	0
guanosine triphosphate	low	5	0
guanine	low	1	0
eye	low	2	0
leptin	low	1	0
pyrimidinones	low	6	0

Protein Targets (1,561)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
RAR-related orphan receptor gamma	27	0	0	27
GLI family zinc finger 3	30	0	0	30
AR protein	37	0	0	37
aldehyde dehydrogenase 1 family, member A1	20	0	0	20
retinoic acid nuclear receptor alpha variant 1	25	0	0	25
retinoid X nuclear receptor alpha	23	0	0	23
estrogen nuclear receptor alpha	41	0	0	41
peroxisome proliferator-activated receptor delta	17	0	0	17
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
activating transcription factor 6	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	14	0	0	14
Histone H2A.x	11	0	0	11
thyroid hormone receptor beta isoform a	11	0	0	11
heat shock protein beta-1	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 1	21	0	0	21
lamin isoform A-delta10	24	0	0	24
Voltage-dependent calcium channel gamma-2 subunit	13	0	0	13
Glutamate receptor 2	13	2	1	16
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	13	0	0	13
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
thioredoxin reductase	19	0	0	19
GALC protein	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	22	0	0	22
cytochrome P450 family 3 subfamily A polypeptide 4	23	0	0	23
glucocorticoid receptor [Homo sapiens]	28	0	0	28
estrogen-related nuclear receptor alpha	31	0	0	31
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	12	0	0	12
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	32	0	0	32
Bloom syndrome protein isoform 1	11	0	0	11
geminin	33	0	0	33
peripheral myelin protein 22	12	0	0	12
survival motor neuron protein isoform d	11	0	0	11
muscleblind-like protein 1 isoform 1	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	11	4	4	19
ATP-binding cassette sub-family C member 3	0	26	0	26
Multidrug resistance-associated protein 4	0	26	0	26
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	5	1	10
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	37	0	37
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	10	1	19
Carbonic anhydrase 2	0	10	1	18
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	4	0	5
Carbonic anhydrase 3	0	4	1	8
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	9	0	12
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	4	0	5
Cytochrome P450 2D6	0	5	0	5
Cytochrome P450 2A6	0	1	0	1
Cytochrome P450 2C9	0	12	0	13
5-hydroxytryptamine receptor 2A	0	4	0	4
Androgen receptor	0	12	0	13
Gamma-aminobutyric acid receptor subunit beta-1	11	4	4	19
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	11	4	4	19
Gamma-aminobutyric acid receptor subunit gamma-2	11	4	4	19
Gamma-aminobutyric acid receptor subunit alpha-5	11	4	4	19
Gamma-aminobutyric acid receptor subunit alpha-3	11	4	4	19
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Carbonic anhydrase 4	0	4	1	8
Carbonic anhydrase 6	0	4	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	11	4	4	19
Gamma-aminobutyric acid receptor subunit alpha-2	11	4	4	19
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	2	0	3
Serum paraoxonase/arylesterase 1	0	4	0	4
Dipeptidyl peptidase 4	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	11	4	4	19
Gamma-aminobutyric acid receptor subunit gamma-3	11	4	4	19
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	11	4	4	19
Adenosine receptor A2a	0	2	0	3
5-hydroxytryptamine receptor 2B	0	3	0	3
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	4	0	4
Cytochrome P450 2C19	0	6	0	6
Delta-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	5	1	6
Carbonic anhydrase 5A, mitochondrial	0	4	1	9
Carbonic anhydrase	0	1	0	2
Kappa-type opioid receptor	0	4	1	6
Carbonic anhydrase 7	0	4	1	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	3	1	0	4
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	1	0	2
D(2) dopamine receptor	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	11	5	4	20
Gamma-aminobutyric acid receptor subunit beta-3	11	4	4	19
Gamma-aminobutyric acid receptor subunit beta-2	11	4	4	19
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Fatty-acid amide hydrolase 1	0	3	0	3
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	1	6
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	5	1	10
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	2	6
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	2
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	4
GABA theta subunit	11	4	4	19
Canalicular multispecific organic anion transporter 1	0	26	0	27
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase 15	0	2	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	4	0	6
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	11	4	4	19
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	5	1	10
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	1	9
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Luciferase	5	0	0	5
USP1 protein, partial	17	0	0	17
TDP1 protein	34	0	0	34
Microtubule-associated protein tau	9	0	0	9
peroxisome proliferator activated receptor gamma	17	0	0	17
vitamin D3 receptor isoform VDRA	6	0	0	6
thyroid hormone receptor beta isoform 2	27	0	0	27
flap endonuclease 1	8	0	0	8
serine/threonine-protein kinase PLK1	4	0	0	4
eyes absent homolog 2 isoform a	2	0	0	2
DNA polymerase eta isoform 1	3	0	0	3
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Bile salt export pump	0	5	0	5
Rap guanine nucleotide exchange factor 3	5	0	0	5
Cellular tumor antigen p53	23	0	0	23
Rap guanine nucleotide exchange factor 4	3	0	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	16	0	0	16
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
pregnane X nuclear receptor	29	0	0	29
nuclear factor erythroid 2-related factor 2 isoform 2	10	0	0	11
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
Cyclin-dependent kinase 1	0	1	4	5
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	7	0	0	7
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	3	5
ATPase family AAA domain-containing protein 5	12	0	0	12
Ataxin-2	18	0	0	18
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	11	0	0	11
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
2-dehydropantoate 2-reductase	0	1	2	3
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	7	3	10
Delta-type opioid receptor	0	5	2	7
Kappa-type opioid receptor	0	7	2	9
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	4	0	0	4
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	3	5
P2X purinoceptor 2	0	0	1	1
acetylcholinesterase	9	0	0	9
phosphopantetheinyl transferase	8	0	0	8
SMAD family member 2	8	0	0	8
ATAD5 protein, partial	10	0	0	10
Fumarate hydratase	9	0	0	9
NFKB1 protein, partial	9	0	0	9
PPM1D protein	7	0	0	7
SMAD family member 3	8	0	0	8
Thrombopoietin	3	0	0	3
caspase 7, apoptosis-related cysteine protease	7	0	0	7
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
thyroid stimulating hormone receptor	11	0	0	11
estrogen receptor 2 (ER beta)	16	0	0	16
progesterone receptor	23	0	0	23
EWS/FLI fusion protein	21	0	0	21
farnesoid X nuclear receptor	17	0	0	17
G	11	0	0	11
cytochrome P450 2D6	12	0	0	12
polyprotein	9	0	0	9
caspase-3	7	0	0	7
thyroid stimulating hormone receptor	10	0	0	10
cytochrome P450 2D6 isoform 1	5	0	0	5
cellular tumor antigen p53 isoform a	4	0	0	4
cytochrome P450 2C9 precursor	2	0	0	2
D(1A) dopamine receptor	8	0	0	8
chromobox protein homolog 1	18	0	0	18
potassium voltage-gated channel subfamily H member 2 isoform d	7	0	0	7
huntingtin isoform 2	4	0	0	4
mitogen-activated protein kinase 1	7	0	0	7
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
nuclear receptor ROR-gamma isoform 1	10	0	0	10
cytochrome P450 3A4 isoform 1	11	0	0	11
muscarinic acetylcholine receptor M1	13	0	0	13
lethal factor (plasmid)	8	0	0	8
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Solute carrier organic anion transporter family member 1A4	0	3	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
5-hydroxytryptamine receptor 4	0	16	0	16
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	17	0	0	17
HLA class I histocompatibility antigen, B alpha chain	11	0	0	11
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	3	5
Integrin beta-3	4	1	1	6
Tyrosine-protein kinase Fyn	0	2	5	7
ATP-dependent translocase ABCB1	0	4	0	4
Aldo-keto reductase family 1 member B1	0	16	0	16
Muscarinic acetylcholine receptor M2	0	7	1	8
Muscarinic acetylcholine receptor M4	0	6	0	6
ATP-dependent translocase ABCB1	0	14	3	27
Integrin alpha-IIb	4	1	1	6
Beta-1 adrenergic receptor	0	6	3	9
Muscarinic acetylcholine receptor M5	0	6	0	6
Alpha-2A adrenergic receptor	0	11	2	14
Adenosine receptor A3	0	6	1	7
Thyroid hormone receptor alpha	0	3	3	6
Thyroid hormone receptor beta	0	3	3	6
Muscarinic acetylcholine receptor M1	0	7	1	8
Beta-3 adrenergic receptor	0	6	3	9
D(2) dopamine receptor	0	8	1	9
Alpha-1B adrenergic receptor	0	5	1	6
Lethal factor	0	1	0	1
Alpha-2B adrenergic receptor	0	8	1	10
Thyroid hormone receptor beta	0	2	0	2
Muscarinic acetylcholine receptor M3	0	7	1	8
ATP-dependent translocase ABCB1	0	4	0	5
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	5	1	6
D(4) dopamine receptor	0	3	0	3
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	16	0	16
Histamine H2 receptor	0	6	0	6
Endothelin-1 receptor	0	3	1	4
5-hydroxytryptamine receptor 2A	0	12	1	13
5-hydroxytryptamine receptor 2C	0	16	1	17
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	16	1	17
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	2	0	2
Melanocortin receptor 5	0	2	0	2
D(3) dopamine receptor	0	11	0	11
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	4	0	4
Squalene synthase	0	1	0	1
5-hydroxytryptamine receptor 2B	0	16	1	17
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	6	1	7
Histamine H2 receptor	5	1	0	7
5-hydroxytryptamine receptor 6	0	8	1	9
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	18	0	0	18
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Sodium-dependent dopamine transporter	0	9	0	9
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	8
Sodium channel protein type 5 subunit alpha	0	7	0	7
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	4	0	4
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	11	0	0	11
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	12	1	13
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	3	0	3
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	3	0	3
cytochrome P450 2C9, partial	11	0	0	11
ATP-dependent phosphofructokinase	15	0	0	15
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
GLS protein	13	0	0	13
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
Solute carrier family 22 member 1	0	8	0	8
Albumin	0	0	2	2
High affinity nerve growth factor receptor	0	1	7	8
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Angiotensin-converting enzyme	0	4	0	4
Alpha-2C adrenergic receptor	0	7	2	10
5-hydroxytryptamine receptor 1A	0	8	2	11
D(1B) dopamine receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Alpha-1D adrenergic receptor	0	7	1	9
5-hydroxytryptamine receptor 1B	0	6	0	6
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Histamine H1 receptor	0	7	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 7	0	5	0	5
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
5-hydroxytryptamine receptor 3B	0	2	0	2
Histamine H3 receptor	0	1	0	1
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Cruzipain	6	0	0	6
Beta-lactamase	0	0	0	2
acid sphingomyelinase	3	0	0	3
apical membrane antigen 1, AMA1	3	0	0	3
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
DNA polymerase beta	2	0	0	2
DNA polymerase iota isoform a (long)	10	0	0	10
DNA polymerase kappa isoform 1	4	0	0	4
60 kDa heat shock protein, mitochondrial	0	1	0	1
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Angiopoietin-1 receptor	0	0	4	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	2
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	1	0	1
Metallo-b-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	0	0	2
Chain A, retinol dehydratase	0	1	0	1
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	4	0	0	4
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	6	0	0	6
hypothetical protein, conserved	1	0	0	1
glucocerebrosidase	3	0	0	3
Rac1 protein	0	0	1	1
IDH1	11	0	0	11
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	3	5	8
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	5
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	4	3	7
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	7	1	1	9
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	1	3
Beta-1 adrenergic receptor	0	1	2	4
Urease	0	1	0	1
Beta-2 adrenergic receptor	0	5	5	10
Alpha-1A adrenergic receptor	0	2	2	5
Alpha-1B adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	2	3	6
glp-1 receptor, partial	13	0	0	13
pregnane X receptor	6	0	0	6
Smad3	11	0	0	11
67.9K protein	10	0	0	10
Parkin	2	0	0	2
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
aryl hydrocarbon receptor	11	0	0	11
peripheral myelin protein 22 isoform 1	5	0	0	5
hemoglobin subunit beta	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Adenosine receptor A2a	0	2	1	3
Adenosine receptor A1	0	5	0	5
Multidrug and toxin extrusion protein 1	0	6	0	6
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Leukotriene C4 synthase	0	0	3	3
Bone morphogenetic protein receptor type-1B	0	0	5	5
Membrane-associated progesterone receptor component 1	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	3	3
Serine/threonine-protein kinase PLK4	0	0	5	5
Serine/threonine-protein kinase 25	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	3	3
Pyridoxal kinase	0	0	4	4
Citron Rho-interacting kinase	0	0	5	5
Serine/threonine-protein kinase RIO3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 7	0	0	3	3
Serine/threonine-protein kinase Chk1	0	0	5	5
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	3	4
Peripheral plasma membrane protein CASK	0	0	3	3
Aurora kinase A	0	0	5	5
Cyclin-G-associated kinase	0	0	5	5
Serine/threonine-protein kinase DCLK1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	3	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	3	3
Ephrin type-B receptor 6	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 3	0	0	4	4
Mitogen-activated protein kinase 13	0	0	3	3
3-phosphoinositide-dependent protein kinase 1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 13	0	0	3	3
Death-associated protein kinase 3	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 2	0	0	5	5
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	4	4
NUAK family SNF1-like kinase 1	0	0	3	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	3	3
Tyrosine-protein kinase JAK2	0	0	5	5
Eukaryotic translation initiation factor 5B	0	0	4	4
Rho-associated protein kinase 2	0	0	5	5
Serine/threonine-protein kinase ULK1	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	5	5
Ribosomal protein S6 kinase alpha-5	0	0	5	5
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	4	4
Ribosomal protein S6 kinase alpha-4	0	0	5	5
Serine/threonine-protein kinase 16	0	0	5	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	3	3
Serine/threonine-protein kinase PAK 3	0	0	3	3
Cyclin-dependent kinase-like 5	0	0	5	5
Serine/threonine-protein kinase 17B	0	0	3	3
Serine/threonine-protein kinase 10	0	0	5	5
Serine/threonine-protein kinase D3	0	0	5	5
Cyclin-dependent kinase 14	0	0	3	3
Structural maintenance of chromosomes protein 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 6	0	0	5	5
Serine/threonine-protein kinase OSR1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	5	5
Serine/threonine-protein kinase LATS1	0	0	5	5
Serine/threonine-protein kinase PAK 4	0	0	5	5
Serine/threonine-protein kinase Chk2	0	0	3	3
Tyrosine-protein kinase ABL1	0	1	6	7
RAF proto-oncogene serine/threonine-protein kinase	0	2	3	5
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	2	2
ADP/ATP translocase 2	0	0	4	4
Protein kinase C beta type	0	0	4	4
Insulin receptor	0	0	5	5
Tyrosine-protein kinase Lck	0	0	5	5
Glycogen phosphorylase, liver form	0	0	4	4
Tyrosine-protein kinase Fes/Fps	0	0	5	5
Macrophage colony-stimulating factor 1 receptor	0	0	3	3
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	0	5	5
Tyrosine-protein kinase Lyn	0	0	5	5
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	5	5
Insulin-like growth factor 1 receptor	0	0	5	5
Signal recognition particle receptor subunit alpha	0	0	4	4
Cytochrome c1, heme protein, mitochondrial	0	0	4	4
Hepatocyte growth factor receptor	0	0	5	5
Tyrosine-protein kinase HCK	0	0	5	5
Proto-oncogene tyrosine-protein kinase ROS	0	0	3	3
Platelet-derived growth factor receptor beta	0	1	5	6
Tyrosine-protein kinase Fgr	0	0	5	5
Wee1-like protein kinase 2	0	0	3	3
Uncharacterized serine/threonine-protein kinase SBK3	0	0	3	3
Serine/threonine-protein kinase A-Raf	0	0	4	4
Mast/stem cell growth factor receptor Kit	0	1	4	5
Glycogen phosphorylase, brain form	0	0	4	4
Breakpoint cluster region protein	0	0	5	5
Serine/threonine-protein kinase pim-1	0	0	5	5
Fibroblast growth factor receptor 1	0	1	5	6
DNA topoisomerase 2-alpha	0	1	5	11
Cyclin-dependent kinase 4	0	0	5	5
ADP/ATP translocase 3	0	0	4	4
Inosine-5'-monophosphate dehydrogenase 2	0	0	4	4
Proto-oncogene tyrosine-protein kinase Src	0	0	5	5
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	4	4
Insulin receptor-related protein	0	0	3	3
Serine/threonine-protein kinase B-raf	0	1	5	6
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	5	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	4	4
Platelet-derived growth factor receptor alpha	0	2	4	6
Tyrosine-protein kinase Fer	0	0	5	5
Protein kinase C alpha type	0	0	4	4
cAMP-dependent protein kinase catalytic subunit alpha	0	0	5	5
Vascular endothelial growth factor receptor 1	0	1	3	4
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	4	4
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	3	3
Casein kinase II subunit alpha'	0	0	6	6
Ras-related protein Rab-6A	0	0	4	4
Serine/threonine-protein kinase MAK	0	0	3	3
Cyclin-dependent kinase 11B	0	0	3	3
Ephrin type-A receptor 1	0	0	5	5
Fibroblast growth factor receptor 2	0	0	3	3
Receptor tyrosine-protein kinase erbB-3	0	0	3	3
Multifunctional protein ADE2	0	0	4	4
Fibroblast growth factor receptor 4	0	0	3	3
Fibroblast growth factor receptor 3	0	0	3	3
cAMP-dependent protein kinase catalytic subunit beta	0	0	5	5
Ferrochelatase, mitochondrial	0	0	4	4
Ribosomal protein S6 kinase beta-1	0	0	5	5
Tyrosine-protein kinase JAK1	0	0	5	5
Protein kinase C eta type	0	0	3	3
Cyclin-dependent kinase 2	0	0	5	5
Beta-adrenergic receptor kinase 1	0	0	5	5
Probable ATP-dependent RNA helicase DDX6	0	0	4	4
Activin receptor type-2A	0	0	3	3
Mitogen-activated protein kinase 3	0	0	5	5
MAP/microtubule affinity-regulating kinase 3	0	0	5	5
Deoxycytidine kinase	0	0	4	4
Mitogen-activated protein kinase 1	0	0	5	5
Ephrin type-A receptor 2	0	0	5	5
Ephrin type-A receptor 3	0	0	3	3
Ephrin type-A receptor 8	0	0	3	3
Ephrin type-B receptor 2	0	0	5	5
Leukocyte tyrosine kinase receptor	0	0	3	3
Non-receptor tyrosine-protein kinase TYK2	0	0	5	5
UMP-CMP kinase	0	0	4	4
Phosphatidylethanolamine-binding protein 1	0	0	4	4
Wee1-like protein kinase	0	0	5	5
Heme oxygenase 2	0	0	4	4
Tyrosine-protein kinase receptor UFO	0	0	3	3
Mitogen-activated protein kinase 4	0	0	3	3
S-adenosylmethionine synthase isoform type-2	0	0	4	4
DnaJ homolog subfamily A member 1	0	0	4	4
RAC-alpha serine/threonine-protein kinase	0	1	5	6
RAC-beta serine/threonine-protein kinase	0	0	5	5
G protein-coupled receptor kinase 4	0	0	3	3
Dual specificity protein kinase TTK	0	0	5	5
DNA replication licensing factor MCM4	0	0	4	4
Myosin-10	0	0	4	4
Tyrosine-protein kinase receptor Tie-1	0	0	3	3
Vascular endothelial growth factor receptor 3	0	1	3	4
Vascular endothelial growth factor receptor 2	0	1	3	4
Dual specificity mitogen-activated protein kinase kinase 2	0	4	5	9
Receptor-type tyrosine-protein kinase FLT3	0	0	5	5
Bone morphogenetic protein receptor type-1A	0	0	5	5
Activin receptor type-1B	0	0	5	5
TGF-beta receptor type-1	0	0	5	5
Serine/threonine-protein kinase receptor R3	0	0	5	5
TGF-beta receptor type-2	0	0	5	5
Electron transfer flavoprotein subunit beta	0	0	4	4
Tyrosine-protein kinase CSK	0	0	5	5
Glycine--tRNA ligase	0	0	4	4
Protein kinase C iota type	0	0	5	5
Exosome RNA helicase MTR4	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	3	3
Serine/threonine-protein kinase mTOR	0	1	4	5
Megakaryocyte-associated tyrosine-protein kinase	0	0	3	3
Tyrosine-protein kinase Tec	0	0	5	5
Tyrosine-protein kinase TXK	0	0	3	3
Tyrosine-protein kinase ABL2	0	0	5	5
Tyrosine-protein kinase FRK	0	0	5	5
Tyrosine-protein kinase ZAP-70	0	0	3	3
Tyrosine-protein kinase SYK	0	0	5	5
26S proteasome regulatory subunit 6B	0	0	4	4
Mitogen-activated protein kinase 8	0	0	5	5
Mitogen-activated protein kinase 9	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 4	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 3	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	4	4
Casein kinase I isoform alpha	0	0	5	5
Casein kinase I isoform delta	0	0	5	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	0	3	3
MAP kinase-activated protein kinase 2	0	0	5	5
Cyclin-dependent kinase 8	0	0	3	3
Elongation factor Tu, mitochondrial	0	0	4	4
Choline-phosphate cytidylyltransferase A	0	0	4	4
Cysteine--tRNA ligase, cytoplasmic	0	0	4	4
Casein kinase I isoform epsilon	0	0	5	5
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	4	4
Dual specificity protein kinase CLK1	0	0	5	5
Dual specificity protein kinase CLK2	0	0	5	5
Dual specificity protein kinase CLK3	0	0	5	5
Glycogen synthase kinase-3 alpha	0	0	5	5
Glycogen synthase kinase-3 beta	0	0	5	5
Cyclin-dependent kinase 7	0	0	5	5
Cyclin-dependent kinase 9	0	0	5	5
Ras-related protein Rab-27A	0	0	4	4
Tyrosine-protein kinase Blk	0	0	3	3
Interleukin-1 receptor-associated kinase 1	0	0	5	5
Ribosomal protein S6 kinase alpha-3	0	0	5	5
Cytoplasmic tyrosine-protein kinase BMX	0	0	3	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	3	3
Serine/threonine-protein kinase Nek2	0	0	5	5
Serine/threonine-protein kinase Nek3	0	0	5	5
Serine/threonine-protein kinase Nek4	0	0	3	3
Tyrosine-protein kinase JAK3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	5	5
Serine/threonine-protein kinase PLK1	0	0	5	5
Death-associated protein kinase 1	0	0	3	3
LIM domain kinase 1	0	0	5	5
LIM domain kinase 2	0	0	5	5
Mitogen-activated protein kinase 12	0	0	3	3
Mitogen-activated protein kinase 10	0	0	5	5
Tyrosine--tRNA ligase, cytoplasmic	0	0	4	4
5'-AMP-activated protein kinase subunit gamma-1	0	0	4	5
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	3	4
Ephrin type-B receptor 3	0	0	5	5
Ephrin type-A receptor 5	0	0	5	5
Ephrin type-B receptor 4	0	0	5	5
Ephrin type-B receptor 1	0	0	3	3
Ephrin type-A receptor 4	0	0	5	5
Adenylate kinase 2, mitochondrial	0	0	4	4
Adenosine kinase	0	0	4	4
Hormonally up-regulated neu tumor-associated kinase	0	0	3	3
Serine/threonine-protein kinase SIK1	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 4	0	0	3	3
Ras-related protein Rab-10	0	0	4	4
Cell division control protein 2 homolog	0	0	3	3
Actin-related protein 3	0	0	4	4
Actin-related protein 2	0	0	4	4
Calcium-dependent protein kinase 1	0	0	3	3
GTP-binding nuclear protein Ran	0	0	4	4
Casein kinase II subunit alpha	0	1	4	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	3	3
SRSF protein kinase 2	0	0	3	3
Casein kinase I isoform gamma-2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 9	0	0	3	3
Serine/threonine-protein kinase PknB	0	0	3	3
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	3	3
Cyclin-dependent kinase 6	0	0	4	4
Cyclin-dependent-like kinase 5	0	0	5	5
Cyclin-dependent kinase 16	0	0	5	5
Cyclin-dependent kinase 17	0	0	5	5
ATP-dependent 6-phosphofructokinase, platelet type	0	0	4	4
Protein kinase C epsilon type	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 1	0	4	5	9
Mitogen-activated protein kinase kinase kinase 10	0	0	3	3
DNA topoisomerase 2-beta	0	1	5	12
Protein kinase C theta type	0	0	5	5
Activin receptor type-1	0	0	5	5
Macrophage-stimulating protein receptor	0	0	5	5
Focal adhesion kinase 1	0	0	5	5
Protein kinase C zeta type	0	0	4	4
Protein kinase C delta type	0	0	5	5
Tyrosine-protein kinase BTK	0	0	5	5
Tyrosine-protein kinase receptor TYRO3	0	0	3	3
Cyclin-dependent kinase 18	0	0	5	5
Activated CDC42 kinase 1	0	0	5	5
Epithelial discoidin domain-containing receptor 1	0	0	5	5
Tyrosine-protein kinase ITK/TSK	0	0	3	3
Myotonin-protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 12	0	0	3	3
Tyrosine-protein kinase Mer	0	0	4	4
Serine/threonine-protein kinase 4	0	0	5	5
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	5	6
Serine/threonine-protein kinase PAK 1	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	5	5
Mitogen-activated protein kinase 7	0	0	5	5
Serine/threonine-protein kinase PAK 2	0	0	5	5
Serine/threonine-protein kinase 3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 1	0	0	5	5
cGMP-dependent protein kinase 2	0	0	3	3
Integrin-linked protein kinase	0	0	4	4
Rho-associated protein kinase 1	0	0	5	5
Non-receptor tyrosine-protein kinase TNK1	0	0	5	5
Serine/threonine-protein kinase PRP4 homolog	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	5	5
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	5	5
Activin receptor type-2B	0	0	5	5
Bone morphogenetic protein receptor type-2	0	0	5	5
Protein-tyrosine kinase 6	0	0	5	5
cGMP-dependent protein kinase 1	0	0	5	5
Cyclin-dependent kinase 13	0	0	5	5
Calcium/calmodulin-dependent protein kinase type 1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	5	5
Protein-tyrosine kinase 2-beta	0	0	5	5
Maternal embryonic leucine zipper kinase	0	0	5	5
Structural maintenance of chromosomes protein 1A	0	0	4	4
Chromodomain-helicase-DNA-binding protein 4	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 1	0	0	4	4
Serine/threonine-protein kinase D1	0	0	3	3
Serine/threonine-protein kinase 38	0	0	3	3
Receptor tyrosine-protein kinase erbB-4	0	0	3	3
Ribosomal protein S6 kinase alpha-2	0	0	3	3
Ephrin type-A receptor 7	0	0	4	4
Delta(24)-sterol reductase	0	0	4	4
Ribosomal protein S6 kinase alpha-1	0	0	5	5
Dual specificity testis-specific protein kinase 1	0	0	5	5
Myosin light chain kinase, smooth muscle	0	0	5	5
Mitogen-activated protein kinase 11	0	0	5	5
Serine/threonine-protein kinase STK11	0	0	5	5
Rhodopsin kinase GRK1	0	0	3	3
NT-3 growth factor receptor	0	0	3	3
Serine/threonine-protein kinase N1	0	0	5	5
Serine/threonine-protein kinase N2	0	0	5	5
Mitogen-activated protein kinase 14	0	1	5	6
Calcium/calmodulin-dependent protein kinase type IV	0	0	5	5
Mitogen-activated protein kinase kinase kinase 11	0	0	5	5
BDNF/NT-3 growth factors receptor	0	0	3	3
Mitogen-activated protein kinase 6	0	0	3	3
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	3	3
Discoidin domain-containing receptor 2	0	1	5	6
AP2-associated protein kinase 1	0	0	5	5
Myosin light chain kinase 3	0	0	5	5
Serine/threonine-protein kinase SBK1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 19	0	0	3	3
Putative heat shock protein HSP 90-beta 2	0	0	4	4
Serine/threonine-protein kinase TNNI3K	0	0	3	3
Rab-like protein 3	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	5	5
Serine/threonine-protein kinase MRCK gamma	0	0	5	5
Acyl-CoA dehydrogenase family member 10	0	0	4	4
Serine/threonine-protein kinase Nek5	0	0	3	3
Serine/threonine-protein kinase N3	0	0	4	4
Serine/threonine-protein kinase ULK3	0	0	5	5
Dual serine/threonine and tyrosine protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 15	0	0	3	3
Uncharacterized protein FLJ45252	0	0	4	4
Acyl-CoA dehydrogenase family member 11	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	4	4
Serine/threonine-protein kinase MARK2	0	0	5	5
Serine/threonine-protein kinase TAO1	0	0	5	5
STE20-related kinase adapter protein alpha	0	0	4	4
Myosin-14	0	0	4	4
AarF domain-containing protein kinase 1	0	0	4	4
Serine/threonine-protein kinase tousled-like 2	0	0	3	3
Serine/threonine-protein kinase 32C	0	0	3	3
Serine/threonine-protein kinase pim-3	0	0	3	3
ATP-dependent RNA helicase DDX42	0	0	3	3
Serine/threonine-protein kinase VRK2	0	0	3	3
Myosin light chain kinase family member 4	0	0	3	3
Homeodomain-interacting protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1D	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	5	5
Cyclin-dependent kinase-like 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	1	5	6
Serine/threonine-protein kinase BRSK2	0	0	3	3
Serine/threonine-protein kinase NIM1	0	0	3	3
Serine/threonine-protein kinase ULK2	0	0	3	3
Misshapen-like kinase 1	0	0	5	5
Serine/threonine-protein kinase DCLK2	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	3	3
Casein kinase I isoform alpha-like	0	0	3	3
Homeodomain-interacting protein kinase 4	0	0	3	3
Myosin-IIIa	0	0	3	3
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	3	3
Serine/threonine-protein kinase Nek11	0	0	3	3
Atypical kinase COQ8A, mitochondrial	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	5	5
Mitogen-activated protein kinase 15	0	0	5	5
Serine/threonine-protein kinase Nek9	0	0	5	5
Serine/threonine-protein kinase BRSK1	0	0	3	3
Serine/threonine-protein kinase 35	0	0	3	3
Serine/threonine-protein kinase Nek7	0	0	3	3
Rhodopsin kinase GRK7	0	0	3	3
Serine/threonine-protein kinase 32A	0	0	3	3
Myosin-IIIb	0	0	3	3
ATP-dependent RNA helicase DDX1	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	3	3
Cyclin-dependent kinase-like 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	5	5
Serine/threonine-protein kinase Sgk3	0	0	3	3
Atypical kinase COQ8B, mitochondrial	0	0	3	3
Aurora kinase B	0	0	5	5
MAP/microtubule affinity-regulating kinase 4	0	0	5	5
Calcium/calmodulin-dependent protein kinase type 1G	0	0	4	4
Serine/threonine-protein kinase Nek1	0	0	5	5
Cyclin-dependent kinase 15	0	0	3	3
PAS domain-containing serine/threonine-protein kinase	0	0	4	4
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	5	5
EKC/KEOPS complex subunit TP53RK	0	0	4	4
Dual specificity testis-specific protein kinase 2	0	0	4	4
SRSF protein kinase 1	0	0	3	3
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	5	5
Mitogen-activated protein kinase kinase kinase 5	0	0	5	5
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	3	3
Mitogen-activated protein kinase kinase kinase 3	0	0	5	5
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	5	5
Serine/threonine-protein kinase RIO1	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO2	0	0	3	3
Cyclin-dependent kinase 19	0	0	3	3
Transient receptor potential cation channel subfamily M member 6	0	0	3	3
Testis-specific serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase 33	0	0	3	3
Nucleolar GTP-binding protein 1	0	0	4	4
Serine/threonine-protein kinase D2	0	0	5	5
Serine/threonine-protein kinase DCLK3	0	0	3	3
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	4	4
Serine/threonine-protein kinase SIK2	0	0	5	5
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	3	3
STE20-like serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase TAO3	0	0	5	5
Homeodomain-interacting protein kinase 2	0	0	3	3
Tyrosine-protein kinase Srms	0	0	3	3
Homeodomain-interacting protein kinase 3	0	0	3	3
Serine/threonine-protein kinase PLK3	0	0	3	3
dCTP pyrophosphatase 1	0	0	4	4
Dual specificity protein kinase CLK4	0	0	5	5
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	3	3
Serine/threonine-protein kinase Nek6	0	0	3	3
Casein kinase I isoform gamma-1	0	0	5	5
Serine/threonine-protein kinase PAK 6	0	0	4	4
SNF-related serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase LATS2	0	0	3	3
Serine/threonine-protein kinase 36	0	0	3	3
Phenylalanine--tRNA ligase beta subunit	0	0	4	4
Isoleucine--tRNA ligase, mitochondrial	0	0	4	4
BMP-2-inducible protein kinase	0	0	5	5
Obg-like ATPase 1	0	0	4	4
Midasin	0	0	4	4
Interleukin-1 receptor-associated kinase 4	0	0	5	5
Serine/threonine-protein kinase 32B	0	0	3	3
Mitogen-activated protein kinase kinase kinase 20	0	0	5	5
Cyclin-dependent kinase 12	0	0	4	4
Serine/threonine-protein kinase PLK2	0	0	3	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	3	3
Serine/threonine-protein kinase MARK1	0	0	3	3
Serine/threonine-protein kinase pim-2	0	0	4	4
Serine/threonine-protein kinase PAK 5	0	0	3	3
Serine/threonine-protein kinase 26	0	0	5	5
eIF-2-alpha kinase GCN2	0	0	3	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	4	4
Serine/threonine-protein kinase NLK	0	0	5	5
Serine/threonine-protein kinase 17A	0	0	3	3
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	3	3
Ephrin type-A receptor 6	0	0	3	3
5'-AMP-activated protein kinase subunit gamma-2	0	0	4	5
Serine/threonine-protein kinase TBK1	0	0	5	5
Septin-9	0	0	4	4
Death-associated protein kinase 2	0	0	3	3
Ribosomal protein S6 kinase alpha-6	0	0	5	5
TRAF2 and NCK-interacting protein kinase	0	0	5	5
Serine/threonine-protein kinase tousled-like 1	0	0	3	3
Serine/threonine-protein kinase TAO2	0	0	5	5
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
ALK tyrosine kinase receptor	0	0	3	3
SRSF protein kinase 3	0	0	3	3
Serine/threonine-protein kinase ICK	0	0	5	5
Cyclin-dependent kinase 11A	0	0	3	3
Aurora kinase C	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase SIK3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 2	0	0	5	5
Thyroid hormone receptor-associated protein 3	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 3	0	0	4	4
Serine/threonine-protein kinase MRCK beta	0	0	5	5
Interleukin-1 receptor-associated kinase 3	0	0	5	5
Serine/threonine-protein kinase 24	0	0	5	5
Casein kinase I isoform gamma-3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 4	0	0	5	5
beta-2 adrenergic receptor	3	0	0	3
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Ferritin light chain	7	0	0	7
Vitamin D3 receptor	0	0	1	1
thioredoxin glutathione reductase	8	0	0	8
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	8	2	10
Vitamin D3 receptor	0	1	2	4
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	4	4
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
G protein-coupled receptor kinase 6	0	0	3	3
Serine/threonine-protein kinase ATR	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	3	3
ATP-dependent RNA helicase DHX30	0	0	3	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Albumin	0	2	4	6
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	1	0	2
Beta-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 7	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Acetylcholinesterase	0	2	0	2
Aromatase	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	2	0	2
Deoxycytidine kinase	0	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
15-lipoxygenase, partial	3	0	0	3
RAD51	0	1	0	1
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
caspase-1 isoform alpha precursor	2	0	0	2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	2	0	0	2
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Prothrombin	0	1	0	1
Glandular kallikrein	0	1	0	1
Cell division protein FtsZ	0	0	1	2
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
tumor necrosis factor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	3
Solute carrier organic anion transporter family member 4C1	0	0	0	2
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	3	0	4
Solute carrier organic anion transporter family member 1B1	0	5	0	7
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	1	0	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
nonstructural protein 1	3	0	0	3
LANA	0	0	0	1
NPYLR7B	0	0	1	1
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
thyrotropin-releasing hormone receptor	3	0	0	3
serine-protein kinase ATM isoform a	1	0	0	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
kelch-like ECH-associated protein 1	0	0	0	2
neuropeptide S receptor isoform A	3	0	0	3
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Equilibrative nucleoside transporter 1	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
M-phase phosphoprotein 8	2	0	0	2
D	0	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Estrogen receptor	0	6	1	7
Alpha-synuclein	2	0	0	2
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	2	0	0	2
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Prothrombin	0	0	2	3
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2	0	0	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	1	5
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	5
Glutamate receptor ionotropic, NMDA 2C	0	2	1	5
DNA topoisomerase 2-alpha	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	1	5
Tubulin beta-2B chain	0	1	0	1
Integrase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	1	5
Glutamate receptor ionotropic, NMDA 3A	0	2	1	5
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Cytochrome P450 2J2	0	6	0	6
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	2	0	2
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
transcriptional regulator ERG isoform 3	1	0	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	2
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
Glutamine synthetase	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Cytochrome P450 3A5	0	0	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
Proton-coupled amino acid transporter 1	0	3	0	4
Chymotrypsinogen A	0	1	0	1
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
PINK1	1	0	0	1
bcl-2-related protein A1	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Neutrophil elastase	0	1	0	1
Insulin receptor	0	1	0	1
Integrin alpha-L	0	1	1	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Histone deacetylase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Histone deacetylase 2	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Histone deacetylase 6	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Glucocorticoid receptor	0	8	2	10
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Toll-like receptor 2	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	0	0	1
Dynamin-1	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	1	2
G-protein coupled receptor 84	0	1	1	2
Atrial natriuretic peptide receptor 1	0	1	0	1
Casein kinase II subunit beta	0	0	1	1
Casein kinase II subunit alpha 3	0	0	1	1
dopamine D1 receptor	2	0	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	3
Beta-1 adrenergic receptor	0	2	1	4
D(3) dopamine receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	0	1	1
Alpha-1D adrenergic receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Estrogen receptor beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	3
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Programmed cell death protein 4	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Vpr	1	0	0	1
Progesterone receptor	0	2	1	3
Mineralocorticoid receptor	0	2	0	3
Estrogen receptor beta	0	1	1	2
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Endothelin-1 receptor	0	1	0	1
Protease	0	2	1	3
Protein-arginine deiminase type-4	0	2	0	2
Beta-2 adrenergic receptor	0	0	1	3
Thymidine phosphorylase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Transthyretin	0	1	0	3
Proliferating cell nuclear antigen	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
Cyclin-dependent kinase 10	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
endonuclease IV	1	0	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Plasma kallikrein	0	0	0	1
SLC16A10 protein	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Malate dehydrogenase	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Multidrug resistance-associated protein 1	0	2	1	4
Chloroquine resistance transporter	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Butyrophilin subfamily 3 member A1	0	0	1	2
Geranylgeranyl pyrophosphate synthase	0	2	0	3
72 kDa type IV collagenase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (140)

Protein Targets (1,561)

Noonan Syndrome

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (140)

Drugs Studied (139)

Protein Targets (1,561)