Page last updated: 2024-09-28

Pasteurellosis, Pneumonic

Bovine respiratory disease found in animals that have been shipped or exposed to CATTLE recently transported. The major agent responsible for the disease is MANNHEIMIA HAEMOLYTICA and less commonly, PASTEURELLA MULTOCIDA or HAEMOPHILUS SOMNUS. All three agents are normal inhabitants of the bovine nasal pharyngeal mucosa but not the LUNG. They are considered opportunistic pathogens following STRESS, PHYSIOLOGICAL and/or a viral infection. The resulting bacterial fibrinous BRONCHOPNEUMONIA is often fatal.

Synonyms(2)

Synonym
Pasteurellosis, Pneumonic
Shipping Fever

Research Excerpts

Overview

ExcerptReference
"Pneumonic pasteurellosis is an economically important infectious disease in the small ruminant industry which causes sudden death and loss for farmers."( Abba, Y; Bitrus, AA; Chung, ELT; Jesse, FFA; Lila, MAM; Maslamany, D; Muniandy, KV; Norsidin, MJ; Tan, AHAR, 2019)

Treatment

ExcerptReference
"During the outbreak of shipping fever metrenperone showed effective antipyretic properties, and all the calves treated with it made a complete recovery."( Close, R; Genicot, B; Lekeux, P; Lindsey, JK; Mouligneau, F; Rollin, F, 1993)
"When used to treat pneumonic pasteurellosis in calves, danofloxacin and enrofloxacin can be expected to deliver concentration-dependent bactericidal activity against M."( Shostrom, VK; Skogerboe, TL; TerHune, TN; Weigel, DJ, 2005)

Research

Studies (142)

TimeframeStudies, This Condition (%)All Conditions %
pre-199017 (11.97)23.3326
1990's45 (31.69)12.5806
2000's59 (41.55)18.1394
2010's20 (14.08)28.8240
2020's1 (0.70)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lactic acid0low10
formaldehyde0low10
histamine0low10
nitrites0low10
palmitic acid0low10
5,8,11,14-eicosatetraynoic acid0low10
aztreonam0low10
verapamil0low10
ciprofloxacin0medium31
clenbuterol0low10
hydroxyurea0low10
iodoacetamide0low10
nifedipine0low10
propranolol0low10
sulfadimethoxine0low10
sulfamethazine0low10
sulfanilamide0low10
fluprednisolone0low10
penicillin g0low10
chloramphenicol0low10
carbostyril0medium52
ampicillin0low10
congo red0low10
erythromycin0low20
spectinomycin0low20
flumethasone0low10
mannose0low20
streptomycin0low30
acetylglucosamine0low10
thiamphenicol0medium87
tetradecanoylphorbol acetate0low10
clonixin0low10
amoxicillin0low10
substance p0low10
flunixin meglumine0low10
difloxacin0medium21
marbofloxacin0medium11
cephalosporin c0medium52
web 20860low10
triazoles0low10
enrofloxacin0medium41
danofloxacin0low30
metrenperone0low10
fibrinogen0low20
u 731220low10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine0low10
florfenicol0medium87
omega-n-methylarginine0low20
depsidomycin0low10
isoflupredone acetate0low10
fibrin0low30
epiglucan0low10
laminaran0low10
acriflavine0low10
tiamulin0medium11
alpha-chymotrypsin0low10
dinoprostone0medium11
leukotriene b40low10
morantel0low10
cysteine0low10
tulathromycin0medium1511
mocetinostat0low20
g(m1) ganglioside0low10
bimosiamose disodium0low20
calcimycin0low10
cecropin b protein, insecta0medium11
ceftiofur0medium52
tildipirosin0medium11
piperidines0low10
interleukin-80medium71
tilmicosin0medium1811
tylosin0medium1912
leukotoxin0medium382
chlortetracycline0low20
oxytetracycline, anhydrous0low70
piroxicam0low10
lactoferrin0low30
thromboplastin0low10
muramidase0low10
exudates0low10

Protein Targets (746)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE140014
Chain A, Cruzipain7007
regulator of G-protein signaling 49009
Platelet-activating factor receptor0304
Inositol monophosphatase 13003
Chain A, TYROSYL-DNA PHOSPHODIESTERASE8008
Chain A, 2-oxoglutarate Oxygenase100010
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
Chain A, Ferritin light chain3003
Luciferase8008
Mcl-10101
phosphopantetheinyl transferase5005
Myeloid cell leukemia sequence 1 (BCL2-related)0101
Microtubule-associated protein tau7007
thioredoxin glutathione reductase3003
aldehyde dehydrogenase 1 family, member A1130013
envelope glycoprotein0101
core protein, partial0101
bromodomain adjacent to zinc finger domain 2B6006
euchromatic histone-lysine N-methyltransferase 2160016
Bloom syndrome protein isoform 16006
polyunsaturated fatty acid lipoxygenase ALOX122002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 19009
glyceraldehyde-3-phosphate dehydrogenase isoform 10101
DNA polymerase beta4004
ubiquitin carboxyl-terminal hydrolase 2 isoform a5005
eukaryotic translation initiation factor 4 gamma 1 isoform 40202
eukaryotic translation initiation factor 4E isoform 10202
geminin160016
DNA polymerase kappa isoform 19009
Vif0101
Tat0101
survival motor neuron protein isoform d5005
histone acetyltransferase KAT2A isoform 19009
DNA dC->dU-editing enzyme APOBEC-3G isoform 11102
dual specificity protein phosphatase 60101
POsterior Segregation0001
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
bcl-2-like protein 1 isoform Bcl-X(L)0101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M20101
Caspase-10101
Zinc finger protein mex-50001
ATP-dependent phosphofructokinase7007
Putative glycosyltransferase WbgO0001
Cytochrome P450 3A4010111
Cannabinoid receptor 10101
Killer cell lectin-like receptor subfamily B member 1A0101
Early activation antigen CD690101
acetylcholinesterase7007
hypoxia-inducible factor 1 alpha subunit3003
RAR-related orphan receptor gamma130013
SMAD family member 24004
Fumarate hydratase5005
SMAD family member 34004
TDP1 protein190019
GLI family zinc finger 3120012
AR protein180018
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)3003
nuclear receptor subfamily 1, group I, member 39009
progesterone receptor7007
cytochrome P450 family 3 subfamily A polypeptide 4100010
glucocorticoid receptor [Homo sapiens]9009
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha7007
estrogen-related nuclear receptor alpha170017
farnesoid X nuclear receptor7007
pregnane X nuclear receptor120012
estrogen nuclear receptor alpha270027
cytochrome P450 2D68008
polyprotein5005
67.9K protein3003
peroxisome proliferator-activated receptor delta4004
peroxisome proliferator activated receptor gamma6006
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
caspase-31001
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
thyroid stimulating hormone receptor8008
activating transcription factor 65005
thyrotropin-releasing hormone receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x4004
potassium voltage-gated channel subfamily H member 2 isoform d6006
thyroid hormone receptor beta isoform 2150015
nuclear factor erythroid 2-related factor 2 isoform 19009
Voltage-dependent calcium channel gamma-2 subunit5005
Interferon beta7007
Cellular tumor antigen p53150015
Glutamate receptor 25005
Spike glycoprotein5005
ATPase family AAA domain-containing protein 54004
Ataxin-27007
Chain A, Beta-lactamase6006
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
apical membrane antigen 1, AMA15005
Beta-lactamase 0002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)9009
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010011
Bile salt export pump0505
Bile salt export pump018018
Beta-lactamase SHV-10002
Beta-lactamase SHV-10002
Cytochrome P450 2C9 0707
Beta-lactamase0002
Kappa-type opioid receptor0103
Solute carrier family 15 member 10404
Solute carrier family 15 member 10202
Cytochrome P450 2J20606
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20303
Beta-lactamase 0002
Beta-lactamase 0002
Solute carrier family 15 member 20303
Beta-lactamase 0002
Beta-lactamase 0002
Canalicular multispecific organic anion transporter 10909
Chain A, Mutant Al2 6e7p9g0011
Beta-lactamase 0002
acid sphingomyelinase3003
GLS protein8008
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Metallo-beta-lactamase0002
Beta-lactamase 0002
chromobox protein homolog 1100010
Carbonic anhydrase 10507
Carbonic anhydrase 206111
60 kDa heat shock protein, mitochondrial0202
Beta-lactamase OXA-70001
10 kDa heat shock protein, mitochondrial0202
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Thiosulfate sulfurtransferase0202
Metallo-beta-lactamase VIM-130002
Efflux transporter 0002
Beta-lactamase 0001
Beta-lactamase Toho-10002
Beta-lactamase 0002
Class D beta-lactamase0002
60 kDa chaperonin 0202
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0002
10 kDa chaperonin 0202
Metallo-b-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0002
Histamine H3 receptor0102
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0002
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
Chain A, JmjC domain-containing histone demethylation protein 3A4004
endonuclease IV1001
glp-1 receptor, partial3003
thioredoxin reductase110011
ClpP1001
electroneutral potassium-chloride cotransporter KCC20011
ATAD5 protein, partial4004
USP1 protein, partial7007
TSHR protein1001
Smad32002
thyroid stimulating hormone receptor6006
nonstructural protein 14004
glucocerebrosidase3003
Parkin3003
arylsulfatase A4004
LacZ protein (plasmid)0011
XBP10101
IDH14004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
serine-protein kinase ATM isoform a1001
lysosomal alpha-glucosidase preproprotein3003
hexokinase-4 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
peripheral myelin protein 22 isoform 14004
type-1 angiotensin II receptor0101
D(1A) dopamine receptor3003
vitamin D3 receptor isoform VDRA100010
nuclear factor erythroid 2-related factor 2 isoform 22002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
glucokinase regulatory protein1001
huntingtin isoform 22002
mitogen-activated protein kinase 13003
flap endonuclease 12002
ras-related protein Rab-9A2002
serine/threonine-protein kinase mTOR isoform 12002
serine/threonine-protein kinase PLK15005
apelin receptor0101
heat shock protein HSP 90-alpha isoform 20001
DNA damage-inducible transcript 3 protein0101
nuclear receptor ROR-gamma isoform 16006
Vpr1001
streptokinase A precursor0066
lamin isoform A-delta10100010
neuropeptide S receptor isoform A1001
Rap guanine nucleotide exchange factor 34004
Amyloid-beta precursor protein1203
Alpha-synuclein2002
D(1A) dopamine receptor1001
Guanine nucleotide-binding protein G2002
TAR DNA-binding protein 434004
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
heat shock protein 90, putative0001
Chain A, serum paraoxonase0101
Carbonic anhydrase 120203
Carbonic anhydrase 30203
Neutrophil cytosol factor 10101
Carbonic anhydrase 40405
Carbonic anhydrase 60304
Carbonic anhydrase 5A, mitochondrial0406
Carbonic anhydrase 70203
Carbonic anhydrase 90406
Carbonic anhydrase 130203
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140203
Carbonic anhydrase 5B, mitochondrial0204
interleukin 82002
EWS/FLI fusion protein9009
G5005
heat shock protein beta-12002
lethal factor (plasmid)2002
Dihydroxyacetone phosphate acyltransferase0001
HLA class I histocompatibility antigen, B alpha chain 5005
30S ribosomal protein S60325
30S ribosomal protein S70325
50S ribosomal protein L150325
50S ribosomal protein L100325
50S ribosomal protein L110325
50S ribosomal protein L7/L120325
50S ribosomal protein L190325
50S ribosomal protein L10325
50S ribosomal protein L200325
50S ribosomal protein L270325
50S ribosomal protein L280325
50S ribosomal protein L290325
50S ribosomal protein L310325
50S ribosomal protein L31 type B0325
50S ribosomal protein L320325
50S ribosomal protein L330325
50S ribosomal protein L340325
50S ribosomal protein L350325
50S ribosomal protein L360325
30S ribosomal protein S100325
30S ribosomal protein S110325
30S ribosomal protein S120325
30S ribosomal protein S130325
30S ribosomal protein S160325
30S ribosomal protein S180325
30S ribosomal protein S190325
30S ribosomal protein S200325
30S ribosomal protein S20325
30S ribosomal protein S30325
30S ribosomal protein S40325
30S ribosomal protein S50325
30S ribosomal protein S80325
30S ribosomal protein S90325
50S ribosomal protein L130325
50S ribosomal protein L140325
50S ribosomal protein L160325
50S ribosomal protein L230325
30S ribosomal protein S150325
50S ribosomal protein L170325
50S ribosomal protein L210325
50S ribosomal protein L300325
50S ribosomal protein L60325
30S ribosomal protein S140325
30S ribosomal protein S170325
30S ribosomal protein S10325
50S ribosomal protein L180325
50S ribosomal protein L20325
50S ribosomal protein L30325
50S ribosomal protein L240325
50S ribosomal protein L40325
50S ribosomal protein L220325
50S ribosomal protein L50325
30S ribosomal protein S210325
50S ribosomal protein L250325
50S ribosomal protein L36 20325
Inositol hexakisphosphate kinase 15005
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial5005
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120101
Protein-arginine deiminase type-40404
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
cytochrome P450 2C9 precursor4004
Gamma-aminobutyric acid receptor subunit pi72110
Cytochrome P450 1A20303
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
Cytochrome P450 2D60303
DNA topoisomerase 2-alpha0104
Gamma-aminobutyric acid receptor subunit beta-172110
Gamma-aminobutyric acid receptor subunit delta72110
Gamma-aminobutyric acid receptor subunit gamma-272110
Gamma-aminobutyric acid receptor subunit alpha-572110
Gamma-aminobutyric acid receptor subunit alpha-372110
DNA gyrase subunit A0102
Gamma-aminobutyric acid receptor subunit gamma-172110
Gamma-aminobutyric acid receptor subunit alpha-272110
Gamma-aminobutyric acid receptor subunit alpha-472110
Gamma-aminobutyric acid receptor subunit gamma-372110
Gamma-aminobutyric acid receptor subunit alpha-672110
Cytochrome P450 2C190303
Multidrug resistance protein MdtK0011
Histamine H2 receptor5016
Gamma-aminobutyric acid receptor subunit alpha-172110
Gamma-aminobutyric acid receptor subunit beta-372110
Gamma-aminobutyric acid receptor subunit beta-272110
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0002
Potassium voltage-gated channel subfamily H member 20708
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0101
GABA theta subunit72110
Gamma-aminobutyric acid receptor subunit epsilon72110
peripheral myelin protein 225005
Beta-2 adrenergic receptor0426
Beta-1 adrenergic receptor0415
5-hydroxytryptamine receptor 1A0719
5-hydroxytryptamine receptor 1B0606
Delta-type opioid receptor0112
Beta-2 adrenergic receptor 0013
Beta-2 adrenergic receptor0125
UDP-glucuronosyltransferase 2B70001
UDP-glucuronosyltransferase 1A30001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
B2 bradykinin receptor0101
Dihydrofolate reductase0001
Dihydrofolate reductase0101
Chymotrypsinogen A0001
Beta-lactamase0101
Beta-lactamase0002
5-hydroxytryptamine receptor 2A0304
Beta-galactosidase0102
Choline O-acetyltransferase0101
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20202
PH domain leucine-rich repeat-containing protein phosphatase 20101
Chymotrypsin-C0101
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
prostaglandin E2 receptor EP2 subtype1001
Solute carrier family 22 member 20002
Solute carrier family 22 member 1 0305
Solute carrier organic anion transporter family member 1A50001
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 60203
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200101
Solute carrier family 22 member 80203
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110102
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
Albumin0033
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB107115
60 kDa chaperonin0101
Chitinase B0101
ATP-dependent translocase ABCB10304
Low molecular weight phosphotyrosine protein phosphatase0101
Cytochrome P450 1B10101
Lanosterol 14-alpha demethylase0101
Multidrug and toxin extrusion protein 10101
transcriptional regulator ERG isoform 34004
twin arginine protein translocation system - TatA protein0001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
nuclear receptor subfamily 1, group I, member 25005
glycogen synthase kinase-3 alpha0001
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
GALC protein1001
transforming acidic coiled-coil-containing protein 30001
Solute carrier family 22 member 30102
Plasma kallikrein0001
Macrophage migration inhibitory factor0202
Histamine H2 receptor0325
Adenosine receptor A10001
5-hydroxytryptamine receptor 1D0001
Adenosine receptor A2a0102
Histamine H1 receptor0123
Histamine H1 receptor0213
Metabotropic glutamate receptor 50112
Histamine H1 receptor0224
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0203
Carbonic anhydrase0103
Histamine H3 receptor0101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 0103
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0103
Carbonic anhydrase0103
Glutamate receptor ionotropic, NMDA 2D0001
Solute carrier family 22 member 10102
Carbonic anhydrase 0103
Equilibrative nucleoside transporter 40001
Glutamate receptor ionotropic, NMDA 3B0001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40102
Carbonic anhydrase 150203
Carbonic anhydrase 130102
Histamine H4 receptor0123
Carboxylic ester hydrolase 0001
Solute carrier family 22 member 20102
Glutamate receptor ionotropic, NMDA 3A0001
Histamine H3 receptor0123
NFKB1 protein, partial3003
cytochrome P450 3A4 isoform 17007
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Stromelysin-10011
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
15-lipoxygenase, partial3003
Thrombopoietin2002
hypothetical protein, conserved2002
alpha-galactosidase1001
cellular tumor antigen p53 isoform a3003
cytochrome P450 2C19 precursor4004
histone deacetylase 9 isoform 31001
M-phase phosphoprotein 82002
muscarinic acetylcholine receptor M13003
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Transient receptor potential cation channel subfamily A member 10011
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
Integrin beta-33003
Integrin alpha-IIb3003
Disintegrin and metalloproteinase domain-containing protein 173003
Leukotriene B4 receptor 10203
Leukotriene B4 receptor 20102
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
PPM1D protein1001
Histone deacetylase 30202
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Histone deacetylase 40101
Histone deacetylase 10202
Histone deacetylase 70101
Histone deacetylase 20202
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
pregnane X receptor1001
beta-2 adrenergic receptor1001
cytochrome P450 2D6 isoform 12002
tumor necrosis factor1001
perilipin-50101
perilipin-10101
atrial natriuretic peptide receptor 2 precursor1001
eyes absent homolog 2 isoform a1001
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
muscleblind-like protein 1 isoform 13003
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 40606
Potassium channel subfamily K member 20011
Glutathione reductase, mitochondrial0202
Muscarinic acetylcholine receptor M20113
Muscarinic acetylcholine receptor M40001
Muscarinic acetylcholine receptor M50001
Adenosine receptor A30314
Muscarinic acetylcholine receptor M10113
Polyunsaturated fatty acid lipoxygenase ALOX150101
Phospholipase A2, membrane associated0001
Alpha-1B adrenergic receptor0314
Muscarinic acetylcholine receptor M30113
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Potassium voltage-gated channel subfamily A member 50101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Thromboxane-A synthase 0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
5-hydroxytryptamine receptor 2C0617
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A2a0213
Adenosine receptor A10202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
C-C chemokine receptor type 20202
Alpha-1A adrenergic receptor0314
Nuclear receptor ROR-gamma1001
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
C-terminal-binding protein 11001
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0405
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Sodium channel protein type 5 subunit alpha0303
Myosin light chain kinase, smooth muscle0101
Sodium channel protein type 9 subunit alpha0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Sodium channel protein type 2 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Broad substrate specificity ATP-binding cassette transporter ABCG20213
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10102
Neutrophil elastase0101
Proteinase-activated receptor 10101
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, endothelial0202
Nitric oxide synthase, brain0202
Nitric oxide synthase, brain 0202
Nitric oxide synthase, inducible0101
Nitric oxide synthase, inducible0202
Collagenase 30101
Nitric oxide synthase, brain0101
WRN1001
Valosin-containing protein0101
thyroid hormone receptor beta isoform a1001
microphthalmia-associated transcription factor isoform 90101
importin subunit beta-1 isoform 11001
snurportin-11001
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Serum paraoxonase/arylesterase 10101
phosphoglycerate kinase1001
Chain A, Fatty acid-binding protein, adipocyte0101
Acetylcholinesterase0101
Toll-like receptor 20101
Prostaglandin G/H synthase 1 0202
Fatty acid-binding protein, intestinal0101
Fatty acid-binding protein, adipocyte0213
Tyrosine-protein phosphatase non-receptor type 10101
Prostaglandin G/H synthase 20101
Fatty acid-binding protein 50213
Peroxisome proliferator-activated receptor alpha1012
Olfactory receptor 51E20011
Transient receptor potential cation channel subfamily V member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Solute carrier family 22 member 60202
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase TEM0102
Beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 10101
Polyunsaturated fatty acid 5-lipoxygenase0101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
Beta-1 adrenergic receptor 0113
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0326
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80202
Beta-3 adrenergic receptor0213
D(2) dopamine receptor0112
Alpha-2B adrenergic receptor0012
Beta-1 adrenergic receptor0315
Alpha-2C adrenergic receptor0124
D(3) dopamine receptor0101
Alpha-2B adrenergic receptor0011
D(1A) dopamine receptor0112
Alpha-2C adrenergic receptor0011
Alpha-2A adrenergic receptor0011
Alpha-1D adrenergic receptor0112
Alpha-1D adrenergic receptor0012
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2A0415
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Sodium-dependent serotonin transporter0404
Cholecystokinin receptor type A0112
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0124
Alpha-1B adrenergic receptor0012
Mu-type opioid receptor0112
Vasopressin V1a receptor0112
Delta-type opioid receptor0112
Kappa-type opioid receptor0112
5-hydroxytryptamine receptor 2B0415
5-hydroxytryptamine receptor 60415
5-hydroxytryptamine receptor 70202
Beta-2 adrenergic receptor0101
Sodium/bile acid cotransporter0101
Sigma non-opioid intracellular receptor 10202
Nuclear receptor subfamily 2 group E member 10022
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0112
Substance-K receptor0202
Substance-P receptor0213
Neuromedin-K receptor0112
Substance-P receptor0101
Substance-K receptor0101
D(2) dopamine receptor0112
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Mas-related G-protein coupled receptor member X20011
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 20112
Cholinesterase0101
5-hydroxytryptamine receptor 2C0101
Acetylcholinesterase0101
Carbonic anhydrase 5A, mitochondrial0101
5-hydroxytryptamine receptor 2B0101
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Protein argonaute-20011
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Luciferin 4-monooxygenase0011
Protein kinase C alpha type0112
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Estrogen receptor0011
Estrogen receptor beta0011
Telomerase reverse transcriptase0101
Glycoprotein0101
Muscarinic acetylcholine receptor M20011
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Multidrug resistance-associated protein 1 0214
D(3) dopamine receptor0202
Chloroquine resistance transporter0101
Solute carrier organic anion transporter family member 1B10202
Platelet-activating factor receptor0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]