Calculosis

A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.

Synonym
Calculosis
Lithiasis

Excerpt	Reference
"Intrascrotal lithiasis is rare."	( García Alonso, J; Gómez Cisneros, SC; Grases Freixedas, F; Lancina Martín, A; Parra Muntaner, L; Sánchez Merino, JM, 2002)
"Rhinolithiasis is the presence of mineralized and calcareous formations located in the nasal cavity."	( Bayram, I; Caksen, H; Dülger, H; Etlik, O; Kiriş, M; Sakin, YF; Yuca, K, 2006)
"Rhinolithiasis is a rare condition but must always be suspected in patients with long standing nasal obstruction, nasal and oral malodor, purulent rhinorrhea and chronic headache."	( Bayram, I; Caksen, H; Dülger, H; Etlik, O; Kiriş, M; Sakin, YF; Yuca, K, 2006)
"Hepatolithiasis is prevalent in East Asia, including Japan, but occurs much less frequently in Western countries."	( Inada, Y; Osuga, T; Shoda, J, 2006)
"Urolithiasis is a disease of a complex, often systemic and not fully unequivocal, etiopathological mechanism, resulting in concrement crystallization The aim of study was the evaluation of frequency of occurrences of crystallization risk states and urolithiasis in children with IBD."	( Czkwianianc, E; Makosiej, R; Małecka-Panas, E; Niedworok, M, 2007)
"Epididymal lithiasis is a dysfunction characterized by formation of calcium-rich stones in the epididymal region of roosters, associated with decreased serum testosterone and loss of fertility."	( Dornas, RA; Hess, RA; Kalapothakis, E; Mahecha, GA; Oliveira, AG; Oliveira, CA, 2008)
"Testicular microlithiasis is a rare cause of testicular enlargement and pediatricians should take this disease into account in the differential diagnosis of suspected precocious puberty."	( Abaci, A; Bober, E; Buyukgebiz, A; Cakmakçi, H; Demir, K; Dundar, B, 2007)
"Enterolithiasis is an uncommon finding of intraluminal calcified meconium."	( Bergholz, R; Wenke, K, 2009)
"Most cases of enterolithiasis are associated with major urogenital and intestinal malformations--especially VACTERL association."	( Bergholz, R; Wenke, K, 2009)
"Epididymal lithiasis is a reproductive dysfunction of roosters that is associated with loss of fertility and is characterized by the formation of calcium stones in the lumen of the efferent ductules of the epididymal region."	( Dornas, RA; Hess, RA; Mahecha, GA; Oliveira, AG; Oliveira, CA; Praes, LC, 2011)
"Nephrolithiasis is a complex disease that results from a combination of factors related to both urine composition and kidney morphoanatomy."	( Costa-Bauzá, A; Fernandez-Cabot, RA; Grases, F; Prieto, RM; Torres, JJ; Tur, F, 2015)
"Urolithiasis is well described in hens, but surgical treatment is uncommon."	( Guillier, D; Modesto, F; van Bruggen, LWL, 2022)
"Hepatolithiasis is prevalent in Southeast Asian regions, and the role of endogenous β-glucuronidase (β-GD) in the formation of hepatolithiasis is being gradually recognised."	( Wang, C; Wang, Y; Wu, S; Yang, Y; Yao, D, 2023)
"Hepatolithiasis is prevalent in Southeast Asian regions, and the role of endogenous β-glucuronidase (β-GD) in the formation of hepatolithiasis is being gradually recognised."	( Wang, C; Wang, Y; Wu, S; Yang, Y; Yao, D, 2023)
"Urolithiasis is a major public health issue due to its increasing prevalence."	( Dominique, D; Lamine, N; Modou, N; Mohamed, D; Mohamed, SS; Motoula Latou, L; Racine, K, 2023)

Excerpt	Reference
"Biliary pseudolithiasis has been reported in patients who received ceftriaxone therapy."	( de Moor, RA; Egberts, AC; Schröder, CH, 1999)
"Microlithiasis has been identified as a cause of idiopathic acute pancreatitis in patients with an intact gallbladder."	( Cai, Q; Goldstein, M; Narahari, N; Okoro, N; Patel, A, 2008)

Excerpt	Reference
"Biliary pseudolithiasis has been reported in patients who received ceftriaxone therapy."	( de Moor, RA; Egberts, AC; Schröder, CH, 1999)
"In calcium and phosphate urolithiasis, dietary therapy is a very useful adjunct."	( FLOCKS, RH, 1950)
"In this study, seven cases of rhinolithiasis, who were diagnosed and treated by rigid nasal endoscopy were presented."	( Bayram, I; Caksen, H; Dülger, H; Etlik, O; Kiriş, M; Sakin, YF; Yuca, K, 2006)
"To appraise the evolution of lithiasis throughout the treatment a noninvasive indirect method of calculi quantification was developed: calculi mass was quantified by densitometry of X-ray images from cystinuric mice before and after treatment."	( Aranda, J; Clèries, R; Colell, G; Espino, M; Feliubadaló, L; Font-Llitjós, M; Frey, IM; Mañas, S; Nunes, V; Palacín, M; Palomo, S; Puertas, S; Visa, J, 2007)
"The rest 45 hepatolithiasis patients without gefitinib treatment served as controls."	( Cheng, NS; Li, FY; Ma, WJ; Mao, H; Shrestha, A; Yang, Q; Zhang, W; Zhou, Y, 2015)
"Biliary lithiasis, or sludge, and nephrolithiasis have been reported as a possible complication of ceftriaxone therapy."	( Agengin, K; Bala, KA; Bora, A; Bulut, MD; Demiroren, K; Dogan, M; Ustyol, L; Yavuz, A, 2017)
"We present two cases of lithiasis in patients treated with mesalazine at high dosage, an adverse effect to betaken into account as a drug lithiasis and which is not even mentioned in the patient information leaflet."	( Benavent, G; Frédérique Scheirs, S; Orts, JA; Vílchez, A, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	109 (40.22)	23.3326
1990's	9 (3.32)	12.5806
2000's	77 (28.41)	18.1394
2010's	53 (19.56)	28.8240
2020's	23 (8.49)	9.53

Drug	Relationship Strength	Studies	Trials
ethylene glycol	low	6	0
ammonium hydroxide	low	1	0
benzene	low	1	0
bromide	low	1	0
carbamates	low	1	0
choline	low	2	0
citric acid, anhydrous	low	3	0
phloroglucinol	low	1	0
hippuric acid	low	1	0
glycine	low	1	0
hydrogen carbonate	low	1	0
inositol	low	1	0
nitrous oxide	medium	1	1
oxalic acid	low	4	0
phenol	low	1	0
phosphoric acid	low	1	0
pyrazinamide	low	1	0
pyridoxine	low	1	0
uric acid	low	28	0
urea	low	2	0
anastrozole	low	1	0
aspirin	low	2	0
ether	low	1	0
etidronate	low	3	0
fentanyl	medium	1	1
fluorouracil	low	1	0
guaifenesin	low	2	0
ibuprofen	low	1	0
lidocaine	low	1	0
iodipamide	low	1	0
isoniazid	low	1	0
ketoprofen	medium	2	1
khellin	low	3	0
mesalamine	low	1	0
metronidazole	low	2	0
midazolam	medium	1	1
ofloxacin	low	1	0
pamidronate	low	1	0
phenacetin	low	2	0
phenolsulfonphthalein	low	2	0
procaine	low	1	0
salicylamide	low	1	0
sulfathiazole	low	1	0
gatifloxacin	low	1	0
theobromine	low	1	0
tiopronin	low	1	0
urethane	low	1	0
penicillamine	low	2	0
prednisone	low	1	0
serine	low	1	0
chloramphenicol	low	1	0
glutamine	low	1	0
lysine	low	1	0
aminopyrine	low	1	0
bromodeoxyuridine	low	1	0
edetic acid	low	2	0
ampicillin	low	2	0
cytarabine	low	1	0
valine	low	1	0
ethylene oxide	low	1	0
tromethamine	medium	1	1
isoprene	low	1	0
dehydrocholic acid	low	1	0
penicillanic acid	low	1	0
framycetin	low	1	0
diatrizoate meglumine	low	1	0
catechin	low	1	0
quinazolines	low	2	0
isoxazoles	medium	1	1
aminophylline	low	1	0
fluorometholone	low	1	0
limestone	low	4	0
dihydrotestosterone	low	1	0
acetylcysteine	low	1	0
calcium citrate	medium	1	1
durapatite	low	1	0
vancomycin	low	1	0
carbonates	low	1	0
technetium	low	1	0
thulium	low	1	0
holmium	low	3	0
barium sulfate	low	3	0
calcium phosphate, dibasic, anhydrous	low	1	0
calcium phosphate, monobasic, anhydrous	low	1	0
tricalcium phosphate	low	4	0
ammonium chloride	low	4	0
ursodeoxycholic acid	medium	3	1
calcium oxalate	low	12	0
amoxicillin	low	1	0
ribavirin	low	1	0
piperacillin	low	1	0
itraconazole	low	1	0
lamivudine	low	1	0
barium oxide	low	1	0
anisodamine	low	1	0
pyrrolidine dithiocarbamate	low	2	0
cephalosporin c	low	2	0
3-methylchromone	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	2	0
fibrinogen	low	2	0
lopinavir	low	1	0
glucuronic acid	low	1	0
vitamin b 6	low	1	0
imipenem, anhydrous	low	1	0
bosentan anhydrous	low	1	0
meglumine iotroxinate	low	1	0
parecoxib	medium	1	1
gefitinib	low	1	0
octacalcium phosphate	low	1	0
sulbactam	low	2	0
naproxen	low	1	0
cinacalcet	low	1	0
atazanavir sulfate	low	3	0
calcium pyrophosphate	low	1	0
atropine	low	1	0
dexketoprofen trometamol	medium	1	1
hydroxydione	low	1	0
ritonavir	low	2	0
fluorocholine	low	1	0
povidone-iodine	low	1	0
sultamicillin	low	2	0
retinol	low	1	0
tacrolimus	low	1	0
cocaine	low	1	0
bromochloroacetic acid	low	2	0
isomethyleugenol	low	1	0
nsc 4347	low	1	0
thiouracil	low	1	0
capsaicin	low	1	0
enclomiphene	low	1	0
thioguanine anhydrous	low	1	0
succimer	low	1	0
lithium	low	2	0
rtki cpd	low	1	0
cystine	low	16	0
cytellin	low	1	0
osteoprotegerin	low	1	0
abacavir, lamivudine drug combination	low	1	0
bilirubin	low	8	0
vitamin k semiquinone radical	low	1	0
cholecalciferol	low	2	0
pulmicort	low	1	0
humulene	low	1	0
tranilast	low	1	0
phenylephrine hydrochloride	low	3	0
sirolimus	low	1	0
morphine	medium	4	1
ergothioneine	low	1	0
barium	low	1	0
indinavir sulfate	low	1	0
nitrofurazone	low	1	0
cysteine	low	1	0
phosphorus	low	5	0
cefotaxime	low	1	0
ammonium sulfate	low	1	0
oxalates	low	21	0
cholestanol	low	1	0
nitrofurantoin	low	1	0
peplomycin	low	1	0
gadolinium dtpa	low	1	0
chlorhexidine	low	1	0
apixaban	low	1	0
struvite	low	1	0
indocyanine green	medium	2	1
dihydrotachysterol	low	1	0
phosphatidylcholines	low	1	0
ro13-9904	low	9	0
piperacillin, tazobactam drug combination	low	1	0
quetiapine fumarate	low	1	0
bms-790052	low	1	0
sofosbuvir	low	1	0
salicylates	low	1	0
whitlockite	low	1	0
technetium tc 99m sulfur colloid	low	1	0
hyaluronoglucosaminidase	low	10	0
diospyros	low	1	0
transforming growth factor alpha	low	1	0
cyclosporine	low	1	0
lactoferrin	low	1	0
technetium tc 99m medronate	low	2	0
rifampin	low	2	0
allopurinol	low	1	0
rifapentine	low	1	0
pyrimidinones	low	1	0

Protein Targets (1,761)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
RAR-related orphan receptor gamma	41	0	0	41
GLI family zinc finger 3	42	0	0	42
AR protein	55	0	0	55
aldehyde dehydrogenase 1 family, member A1	37	0	0	37
retinoic acid nuclear receptor alpha variant 1	43	0	0	43
retinoid X nuclear receptor alpha	35	0	0	35
estrogen nuclear receptor alpha	68	0	0	68
peroxisome proliferator-activated receptor delta	27	0	0	27
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	26	0	0	26
activating transcription factor 6	15	0	0	15
v-jun sarcoma virus 17 oncogene homolog (avian)	18	0	0	18
Histone H2A.x	18	0	0	18
thyroid hormone receptor beta isoform a	16	0	0	16
heat shock protein beta-1	12	0	0	12
nuclear factor erythroid 2-related factor 2 isoform 1	40	0	0	40
lamin isoform A-delta10	34	0	0	34
Voltage-dependent calcium channel gamma-2 subunit	24	0	0	24
Glutamate receptor 2	24	0	0	24
nuclear receptor subfamily 1, group I, member 3	36	0	0	36
cytochrome P450 family 3 subfamily A polypeptide 4	29	0	0	29
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	23	0	0	23
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
acetylcholinesterase	11	0	0	11
dopamine D1 receptor	3	0	0	3
15-lipoxygenase, partial	11	0	0	11
pregnane X receptor	9	0	0	9
phosphopantetheinyl transferase	20	0	0	20
USP1 protein, partial	25	0	0	25
NFKB1 protein, partial	5	0	0	5
Microtubule-associated protein tau	21	0	0	21
Thrombopoietin	7	0	0	7
regulator of G-protein signaling 4	6	0	0	6
glucocorticoid receptor [Homo sapiens]	38	0	0	38
farnesoid X nuclear receptor	25	0	0	25
vitamin D (1,25- dihydroxyvitamin D3) receptor	28	0	0	28
arylsulfatase A	14	0	0	14
euchromatic histone-lysine N-methyltransferase 2	44	0	0	44
Bloom syndrome protein isoform 1	7	0	0	7
D(1A) dopamine receptor	3	0	0	3
thyroid hormone receptor beta isoform 2	34	0	0	34
flap endonuclease 1	13	0	0	13
geminin	46	0	0	46
peripheral myelin protein 22	26	0	0	26
survival motor neuron protein isoform d	19	0	0	19
muscarinic acetylcholine receptor M1	12	0	0	12
Histone deacetylase 3	0	1	0	1
Solute carrier family 22 member 6	0	8	0	9
Histone deacetylase 4	0	1	0	1
Guanine nucleotide-binding protein G	4	0	0	4
Histone deacetylase 1	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Ataxin-2	15	0	0	15
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
ATP-dependent phosphofructokinase	19	0	0	19
interleukin 8	15	0	0	15
TDP1 protein	40	0	0	40
thyroid stimulating hormone receptor	20	0	0	20
estrogen receptor 2 (ER beta)	25	0	0	25
progesterone receptor	24	0	0	24
estrogen-related nuclear receptor alpha	42	0	0	42
IDH1	15	0	0	15
transcriptional regulator ERG isoform 3	8	0	0	8
ras-related protein Rab-9A	4	0	0	4
ATP-binding cassette sub-family C member 3	0	36	0	36
Multidrug resistance-associated protein 4	0	36	0	36
Polyphenol oxidase 2	0	2	0	3
Bile salt export pump	0	56	0	56
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Cellular tumor antigen p53	37	0	0	37
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	3	3	7
Xanthine dehydrogenase/oxidase	0	4	0	4
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	9	0	0	9
Canalicular multispecific organic anion transporter 1	0	34	0	34
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	5
thioredoxin reductase	22	0	0	22
Chain A, Ferritin light chain	7	0	0	7
Luciferase	20	0	0	20
GLS protein	20	0	0	20
pregnane X nuclear receptor	37	0	0	37
G	25	0	0	25
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
chromobox protein homolog 1	27	0	0	27
histone deacetylase 9 isoform 3	1	0	0	1
Interferon beta	28	0	0	28
HLA class I histocompatibility antigen, B alpha chain	25	0	0	25
Nicotinate phosphoribosyltransferase	0	3	0	3
Inositol hexakisphosphate kinase 1	25	0	0	25
cytochrome P450 2C9, partial	25	0	0	25
ORF73	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	14	0	0	14
SMAD family member 2	12	0	0	12
ATAD5 protein, partial	8	0	0	8
Fumarate hydratase	8	0	0	8
PPM1D protein	5	0	0	5
SMAD family member 3	12	0	0	12
caspase 7, apoptosis-related cysteine protease	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
EWS/FLI fusion protein	22	0	0	22
cytochrome P450 2D6	17	0	0	17
polyprotein	8	0	0	8
peroxisome proliferator activated receptor gamma	29	0	0	29
caspase-3	5	0	0	5
thyroid stimulating hormone receptor	7	0	0	7
cytochrome P450 2D6 isoform 1	6	0	0	6
cellular tumor antigen p53 isoform a	10	0	0	10
cytochrome P450 2C9 precursor	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	12	0	0	12
huntingtin isoform 2	6	0	0	6
mitogen-activated protein kinase 1	15	0	0	15
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
urokinase-type plasminogen activator precursor	10	0	0	10
plasminogen precursor	10	0	0	10
urokinase plasminogen activator surface receptor precursor	10	0	0	10
nuclear receptor ROR-gamma isoform 1	20	0	0	20
cytochrome P450 3A4 isoform 1	21	0	0	21
lethal factor (plasmid)	10	0	0	10
Gamma-aminobutyric acid receptor subunit pi	21	2	0	23
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
5-hydroxytryptamine receptor 4	0	8	0	8
Lysine-specific demethylase PHF2	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	3	1	4
Integrin beta-3	7	1	0	8
Tyrosine-protein kinase Fyn	0	3	2	5
ATP-dependent translocase ABCB1	0	6	0	6
Aldo-keto reductase family 1 member B1	0	6	0	6
Muscarinic acetylcholine receptor M2	0	7	2	12
Muscarinic acetylcholine receptor M4	0	6	1	9
ATP-dependent translocase ABCB1	0	13	2	16
Integrin alpha-IIb	7	1	0	8
Beta-1 adrenergic receptor	0	4	0	4
Muscarinic acetylcholine receptor M5	0	7	1	10
Alpha-2A adrenergic receptor	0	7	1	8
Adenosine receptor A3	0	8	0	8
Cytochrome P450 2C8	0	3	0	3
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M1	0	7	3	13
Beta-3 adrenergic receptor	0	4	0	4
D(2) dopamine receptor	0	5	0	5
Androgen receptor	0	8	1	9
Gamma-aminobutyric acid receptor subunit beta-1	21	2	0	23
Alpha-1B adrenergic receptor	0	10	0	10
Lethal factor	0	2	0	2
Alpha-2B adrenergic receptor	0	6	0	6
Thyroid hormone receptor beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-2	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-5	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-3	21	2	0	23
Muscarinic acetylcholine receptor M3	0	6	1	9
ATP-dependent translocase ABCB1	0	6	0	6
Substance-K receptor	0	8	0	8
D(1A) dopamine receptor	0	4	0	4
D(4) dopamine receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-2	21	2	0	23
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	6	1	7
Histamine H2 receptor	0	2	0	2
Endothelin-1 receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	6	0	6
5-hydroxytryptamine receptor 2C	0	8	0	8
Gamma-aminobutyric acid receptor subunit alpha-4	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-3	21	2	0	23
Lysine-specific demethylase 5A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	21	2	0	23
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	6	1	7
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	8	2	12
D(3) dopamine receptor	0	7	0	7
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	6	1	9
Kappa-type opioid receptor	0	8	1	11
5-hydroxytryptamine receptor 2B	0	6	0	6
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	10	0	10
Histamine H2 receptor	12	0	0	13
D(1A) dopamine receptor	2	0	0	2
5-hydroxytryptamine receptor 6	0	6	0	6
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	22	0	2	24
Gamma-aminobutyric acid receptor subunit alpha-1	21	3	0	24
Gamma-aminobutyric acid receptor subunit beta-3	21	2	0	23
Gamma-aminobutyric acid receptor subunit beta-2	21	2	0	23
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Sodium-dependent dopamine transporter	0	6	0	6
Potassium voltage-gated channel subfamily H member 2	0	10	0	10
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	2	0	2
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Lysine-specific demethylase 7A	0	1	0	1
GABA theta subunit	21	2	0	23
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	10	2	12
Gamma-aminobutyric acid receptor subunit epsilon	21	2	0	23
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	1	0	1
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	24	0	0	24
Chain A, Beta-lactamase	11	0	0	11
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Beta-lactamase	0	1	0	5
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	3
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	16	0	0	16
DNA polymerase kappa isoform 1	16	0	0	16
Bile salt export pump	0	10	0	10
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase SHV-1	0	1	0	5
Cytochrome P450 2C9	0	17	1	19
Beta-lactamase	0	1	0	5
Kappa-type opioid receptor	0	4	0	8
Solute carrier family 15 member 1	0	5	0	5
Solute carrier family 15 member 1	0	2	0	2
Cytochrome P450 2J2	0	6	0	6
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	4
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Cruzipain	8	0	0	8
Beta-lactamase	0	2	0	4
acid sphingomyelinase	3	0	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	4
Metallo-beta-lactamase type 2	0	0	0	4
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	1	0	5
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	14	0	0	14
DNA polymerase beta	3	0	0	3
Carbonic anhydrase 1	0	10	0	11
Carbonic anhydrase 2	0	11	0	12
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	2
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	0	2	2
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Thiosulfate sulfurtransferase	0	5	0	5
Metallo-beta-lactamase VIM-13	0	1	0	5
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	4
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	1	0	3
60 kDa chaperonin	0	6	0	6
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	5
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	6	0	6
Metallo-b-lactamase	0	0	0	5
Carbapenem-hydrolyzing beta-lactamase KPC	0	1	0	5
Beta-lactamase class B VIM-2	0	0	0	5
Beta-lactamase VIM-1	0	1	0	5
Aromatase	0	4	0	5
Amine oxidase [flavin-containing] A	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	4	0	5
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)	0	1	0	1
Coagulation factor X	0	1	0	1
Prothrombin	0	2	1	3
Coagulation factor X	0	2	0	2
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Trypsin-3	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	17	0	0	17
Chain B, HADH2 protein	17	0	0	17
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
hypothetical protein, conserved	2	0	0	2
glucocerebrosidase	6	0	0	6
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	9	3	12
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	7	1	8
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	9	0	9
Adenosine receptor A1	0	8	0	9
Adenosine receptor A2a	0	7	0	9
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	9	1	10
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Nuclear receptor ROR-gamma	15	0	0	15
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	6	0	6
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	2	3
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	7	0	8
Muscarinic acetylcholine receptor M1	0	6	1	10
Muscarinic acetylcholine receptor M3	0	5	1	9
Muscarinic acetylcholine receptor M4	0	5	1	9
Muscarinic acetylcholine receptor M5	0	5	1	9
Muscarinic acetylcholine receptor M2	0	5	1	10
Muscarinic acetylcholine receptor M1	0	0	1	2
Alpha-1D adrenergic receptor	0	4	0	4
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Reverse transcriptase/RNaseH	0	0	1	2
Muscarinic acetylcholine receptor	0	3	1	4
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
Endolysin	0	0	2	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	8	0	0	8
vitamin D3 receptor isoform VDRA	16	0	0	16
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	3	0	0	3
Inositol monophosphatase 1	3	0	0	3
Solute carrier organic anion transporter family member 1B3	0	6	0	9
Solute carrier organic anion transporter family member 1B1	0	8	0	11
Cytochrome P450 1A2	0	9	0	11
Cytochrome P450 3A4	0	19	1	23
Cytochrome P450 2D6	0	6	0	7
5-hydroxytryptamine receptor 1A	0	5	0	5
Nonstructural protein 5A	0	1	1	2
Nuclear receptor subfamily 1 group I member 2	0	0	7	7
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	0	3	1	4
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
Endothelin-1 receptor	0	1	0	1
Carbonic anhydrase 4	0	6	0	6
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase 15	0	4	0	4
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
Nuclear hormone receptor family member daf-12	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	2	0	2
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
ATPase family AAA domain-containing protein 5	11	0	0	11
67.9K protein	11	0	0	11
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Acetylcholinesterase	0	3	0	3
Cannabinoid receptor 2	0	1	0	1
D(2) dopamine receptor	0	1	1	2
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
peripheral myelin protein 22 isoform 1	7	0	0	7
neuropeptide S receptor isoform A	5	0	0	5
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Carbonic anhydrase 6	0	3	0	3
Sucrase-isomaltase, intestinal	0	1	0	1
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	1	1	2
Beta-secretase 1	0	3	0	3
Carbonic anhydrase 3	0	3	0	3
Dihydroorotate dehydrogenase	0	1	0	1
Beta-lactamase	0	1	0	3
Beta-lactamase	0	2	0	3
Metallo-beta-lactamase VIM-19	0	0	0	3
Beta-lactamase	0	1	0	3
Albumin	0	2	7	15
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Solute carrier family 22 member 6	0	7	0	9
Solute carrier family 22 member 7	0	2	0	2
BlaVIM-1	0	0	0	3
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	6	0	6
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Solute carrier family 22 member 7	0	1	0	1
aryl hydrocarbon receptor	21	0	0	21
streptokinase A precursor	0	0	4	4
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
PAX8	0	0	0	3
glp-1 receptor, partial	8	0	0	8
PINK1	2	0	0	2
Parkin	4	0	0	4
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	2	0	2
cytochrome P450 2C19 precursor	6	0	0	6
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
importin subunit beta-1 isoform 1	4	0	0	4
ubiquitin-conjugating enzyme E2 N	0	2	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
protein AF-9 isoform a	0	0	0	2
snurportin-1	4	0	0	4
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	2
bcl-2-related protein A1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	3	0	4
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	4	0	4
Glutathione reductase, mitochondrial	0	3	0	4
72 kDa type IV collagenase	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Trypanothione reductase	0	1	0	1
Alpha-synuclein	4	2	0	6
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Rap guanine nucleotide exchange factor 4	1	0	0	1
Multidrug and toxin extrusion protein 1	0	5	0	5
Spermine oxidase	0	1	0	1
60 kDa chaperonin	0	2	0	2
Vitamin D3 receptor	0	2	2	6
Glycine receptor subunit alpha-1	0	0	3	3
Vitamin D3 receptor	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Smad3	10	0	0	10
Extracellular calcium-sensing receptor	0	0	1	1
Angiotensin-converting enzyme 2	0	1	2	3
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	4	2	6
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Amyloid-beta precursor protein	1	4	0	5
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
D	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent dopamine transporter	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Sodium-dependent serotonin transporter	0	5	0	6
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	1	4
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	4
Glutamate receptor ionotropic, NMDA 2B	0	3	1	4
Glutamate receptor ionotropic, NMDA 2C	0	3	1	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	3	1	4
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	1	4
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	3	0	3
endonuclease IV	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	7	0	0	7
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	1	0	2
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	2	3
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	1	0	2
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	2	3
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Hsf1 protein	0	0	2	2
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
thyrotropin-releasing hormone receptor	1	0	0	1
Glucocorticoid receptor	0	7	3	11
Sex hormone-binding globulin	0	1	1	2
Progesterone receptor	0	1	0	1
Progesterone receptor	0	2	1	3
Glucocorticoid receptor	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Sex hormone-binding globulin	0	1	0	1
Androgen receptor	0	3	2	7
Androgen receptor	0	1	1	2
Mineralocorticoid receptor	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Angiotensin-converting enzyme	0	1	1	2
Cannabinoid receptor 2	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	2	2
Neuropeptide FF receptor 2	0	0	0	1
ALK tyrosine kinase receptor	0	1	1	2
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Estrogen receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	4	0	4
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	1	2	3
Beta-2 adrenergic receptor	0	2	0	2
Thromboxane-A synthase	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
histone acetyltransferase KAT2A isoform 1	12	0	0	12
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Delta-type opioid receptor	0	3	0	4
Delta-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	4	2	9
Kappa-type opioid receptor	0	3	1	5
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	3	1	6
Mu-type opioid receptor	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	3	0	3
lysosomal alpha-glucosidase preproprotein	2	0	0	2
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	4	0	0	4
hemoglobin subunit beta	2	0	0	2
Vpr	2	0	0	2
Solute carrier family 22 member 8	0	0	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
DNA gyrase subunit B	0	0	0	1
DNA gyrase subunit A	0	3	0	4
DNA gyrase subunit B	0	3	0	4
DNA topoisomerase 4 subunit B	0	0	0	1
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	0	2	3
DNA gyrase subunit A	0	0	0	1
DNA gyrase subunit A	0	4	0	5
Leukotriene C4 synthase	0	0	1	1
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
epidermal growth factor receptor isoform a precursor	1	1	0	2
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Serine/threonine-protein kinase PLK4	0	0	2	2
Serine/threonine-protein kinase 25	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Pyridoxal kinase	0	0	2	3
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	1	2	3
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
NUAK family SNF1-like kinase 1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	1	1
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	0	2	2
Cyclin-dependent kinase 14	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase OSR1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Serine/threonine-protein kinase Chk2	0	0	1	1
Tyrosine-protein kinase ABL1	0	1	2	3
RAF proto-oncogene serine/threonine-protein kinase	0	0	1	1
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Cytochrome P450 2E1	0	1	0	1
Protein kinase C beta type	0	0	2	2
Insulin receptor	0	1	2	3
Cyclin-dependent kinase 1	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	0	1	1
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	2	3
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	1	2	3
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	2	2
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	2	2
Mast/stem cell growth factor receptor Kit	0	0	1	1
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	2	2
Fibroblast growth factor receptor 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Insulin receptor-related protein	0	0	1	1
Serine/threonine-protein kinase B-raf	0	1	2	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	2	2
Platelet-derived growth factor receptor alpha	0	0	1	1
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	0	2	2
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
Vascular endothelial growth factor receptor 1	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Ephrin type-A receptor 1	0	0	2	2
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	1	2
Multifunctional protein ADE2	0	0	2	2
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Protein kinase C eta type	0	0	1	1
Cyclin-dependent kinase 2	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Cruzipain	0	1	0	1
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Activin receptor type-2A	0	0	1	1
Mitogen-activated protein kinase 3	0	1	2	3
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Mitogen-activated protein kinase 1	0	0	2	2
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Ephrin type-B receptor 2	0	0	2	2
Leukocyte tyrosine kinase receptor	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
G protein-coupled receptor kinase 4	0	0	1	1
Cytochrome P450 2C19	0	7	0	8
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Type-1 angiotensin II receptor	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
Serine/threonine-protein kinase receptor R3	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Serine/threonine-protein kinase mTOR	0	3	2	5
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase ZAP-70	0	0	1	1
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	1	2	3
Casein kinase I isoform delta	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	1	3
MAP kinase-activated protein kinase 2	0	0	2	2
Cyclin-dependent kinase 8	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Tyrosine-protein kinase Blk	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 12	0	0	1	1
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	1	2	3
Ephrin type-B receptor 1	0	0	1	1
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Ras-related protein Rab-10	0	0	2	2
Cell division control protein 2 homolog	0	0	1	1
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
Calcium-dependent protein kinase 1	0	0	1	1
GTP-binding nuclear protein Ran	0	0	2	2
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-2	0	0	2	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Synaptic vesicular amine transporter	0	2	0	2
Protein kinase C epsilon type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
DNA topoisomerase 2-beta	0	0	2	2
Transcription factor p65	0	2	0	2
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C zeta type	0	0	2	2
Protein kinase C delta type	0	0	2	2
Tyrosine-protein kinase BTK	0	0	2	2
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Serine/threonine-protein kinase PAK 1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
cGMP-dependent protein kinase 2	0	0	1	1
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Mitogen-activated protein kinase 11	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Mitogen-activated protein kinase 14	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Cyclin-dependent kinase-like 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	2	2
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Aurora kinase B	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
SRSF protein kinase 1	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
Serine/threonine-protein kinase DCLK3	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Casein kinase I isoform gamma-1	0	0	2	2
Serine/threonine-protein kinase PAK 6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Serine/threonine-protein kinase 32B	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
Serine/threonine-protein kinase PLK2	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
eIF-2-alpha kinase GCN2	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Death-associated protein kinase 2	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	1	8
SRSF protein kinase 3	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	2	2
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	3	0	3
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	1
Amino acid transporter	0	3	0	3
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Proton-coupled amino acid transporter 1	0	3	0	3
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Rap guanine nucleotide exchange factor 3	4	0	0	4
Dihydrofolate reductase	0	3	0	3
Acid-sensing ion channel 3	0	1	0	1
Albumin	0	1	0	1
Albumin	0	0	2	2
Cholinesterase	0	1	0	1
Fatty acid-binding protein, intestinal	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	5
UDP-glucuronosyltransferase 2B7	0	3	0	6
Prostaglandin G/H synthase 1	0	1	0	1
Caspase-1	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	5
UDP-glucuronosyltransferase 1A3	0	0	0	3
Aldo-keto reductase family 1 member C3	0	2	0	2
Caspase-3	0	3	0	3
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Caspase-4	0	3	0	3
Caspase-5	0	3	0	3
Caspase-9	0	3	0	3
Acid-sensing ion channel 1	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	5
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase TEM	0	2	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Gag-Pol polyprotein	0	4	0	4
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	3	0	3
Replicase polyprotein 1ab	0	4	2	6
Replicase polyprotein 1ab	0	8	2	10
Gag-Pol polyprotein	0	4	0	4
Alpha-1D adrenergic receptor	0	4	0	4
Gag-Pol polyprotein	0	3	0	3
Thromboxane-A synthase	0	0	0	2
Genome polyprotein	0	1	0	1
Protease	0	6	3	13
Protease	0	6	4	10
Protease	0	1	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
Sodium/myo-inositol cotransporter 2	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2A6	0	2	1	3
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	3	0	4
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	4
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
GALC protein	4	0	0	4
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Capsid protein	0	1	1	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, PROTEASE RETROPEPSIN	0	1	0	1
Chain B, PROTEASE RETROPEPSIN	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	1	2	3
Transmembrane protease serine 2	0	0	2	2
Gag-Pol polyprotein	0	2	0	2
Procathepsin L	0	0	2	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
CAAX prenyl protease 1 homolog	0	1	0	1
Plasmepsin V	0	2	0	2
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Cationic amino acid transporter 3	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	5
Tumor necrosis factor	0	1	0	1
Neuraminidase	0	1	0	1
Platelet-activating factor receptor	1	0	0	1
Cystathionine gamma-lyase	0	2	0	2
Protein-arginine deiminase type-4	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Hydroxyacid oxidase 1	0	1	0	1
large T antigen	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Translocator protein	0	1	1	2
UDP-glucuronosyltransferase 1-6	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	3	0	3
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	0	2
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
thioredoxin glutathione reductase	5	0	0	5
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Metabotropic glutamate receptor 5	0	1	0	1
Snake venom metalloproteinase BaP1	0	1	0	1
NAD(+) hydrolase SARM1	0	2	0	2
STE24	0	0	0	1
Trypsin	0	0	0	1
ClpP	1	0	0	1
Mcl-1	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
Fatty acid synthase	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Chain A, Pyruvate kinase, M2 isozyme	0	1	0	1
Chain A, Phosphonopyruvate hydrolase	0	1	0	1
Chain A, Phosphoenolpyruvate-protein phosphotransferase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
alpha-galactosidase	3	0	0	3
Carbonic anhydrase 12	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Sulfotransferase 1A1	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 9	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
M-phase phosphoprotein 8	2	0	0	2
Cyclooxygenase-2	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Ornithine transcarbamylase, mitochondrial	0	1	0	1
2-dehydropantoate 2-reductase	0	1	0	1
Nociceptin receptor	0	1	0	1
Fe(3+)-Zn(2+) purple acid phosphatase	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
Beta-lactamase	0	1	0	2
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
Estrogen receptor beta	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
NS5	0	0	2	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	3	1	6
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Cytochrome P450 2B6	0	1	1	2
Solute carrier organic anion transporter family member 1A2	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
Vasopressin V1a receptor	0	2	0	2
Stromelysin-1	0	0	1	1
Integrase	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Cholinesterase	0	1	0	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Myosin-10	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Cereblon isoform 4	0	1	0	1
RNA-directed RNA polymerase	0	0	1	2
Protein cereblon	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Transcriptional activator protein LasR	0	1	0	1
Protein arginine N-methyltransferase 6	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Adenosine receptor A2b	0	2	0	3
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Renin	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Bcl-2-like protein 1	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Angiotensin-converting enzyme	0	1	0	1
MSH	0	0	0	1
pyruvate kinase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
Ornithine decarboxylase	1	0	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Ileal sodium/bile acid cotransporter	0	1	0	1
Bile acid receptor	0	0	1	1
M1-family alanyl aminopeptidase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (271)

Protein Targets (1,761)

Calculosis

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (271)

Drugs Studied (212)

Protein Targets (1,761)