Page last updated: 2024-08-05 12:29:34
6beta-hydroxy steroid
Any 6-hydroxy steroid in which the 6-hydroxy substituent has beta-configuration.
ChEBI ID: 36851
Members (4)
Member | Definition | Role |
---|---|---|
6 beta-hydroxycortisol | A C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. | 6beta-hydroxycortisol |
cerevisterol | An ergostanoid that is (22E)-ergosta-7,22-diene substituted by hydroxy groups at positions 3, 5 and 6 (the 3beta,5alpha,6beta stereoisomer). It has been isolated from the fungus, Xylaria species. | cerevisterol |
cholestane-3,5,6-triol, (3beta, 5alpha, 6beta)-isomer | 5alpha-cholestane-3beta,5,6beta-triol | |
physalin d | A physalin with antimalarial and antimycobacterial activities isolated from Physalis angulata. | physalin D |
Research
Studies (327)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 81 (24.77) | 18.7374 |
1990's | 64 (19.57) | 18.2507 |
2000's | 86 (26.30) | 29.6817 |
2010's | 81 (24.77) | 24.3611 |
2020's | 15 (4.59) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 65 (19.40%) | 5.53% |
Reviews | 14 (4.18%) | 6.00% |
Case Studies | 2 (0.60%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 254 (75.82%) | 84.16% |