Page last updated: 2024-08-05 12:29:34

6beta-hydroxy steroid

Any 6-hydroxy steroid in which the 6-hydroxy substituent has beta-configuration.

ChEBI ID: 36851

Members (4)

MemberDefinitionRole
6 beta-hydroxycortisolA C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo.6beta-hydroxycortisol
cerevisterolAn ergostanoid that is (22E)-ergosta-7,22-diene substituted by hydroxy groups at positions 3, 5 and 6 (the 3beta,5alpha,6beta stereoisomer). It has been isolated from the fungus, Xylaria species.cerevisterol
cholestane-3,5,6-triol, (3beta, 5alpha, 6beta)-isomer5alpha-cholestane-3beta,5,6beta-triol
physalin dA physalin with antimalarial and antimycobacterial activities isolated from Physalis angulata.physalin D

Research

Studies (327)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199081 (24.77)18.7374
1990's64 (19.57)18.2507
2000's86 (26.30)29.6817
2010's81 (24.77)24.3611
2020's15 (4.59)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials65 (19.40%)5.53%
Reviews14 (4.18%)6.00%
Case Studies2 (0.60%)4.05%
Observational0 (0.00%)0.25%
Other254 (75.82%)84.16%