1,3,6-trihydroxy-2-methyl-9,10-anthraquinone

Description

1,3,6-trihydroxy-2-methyl-9,10-anthraquinone is a complex organic molecule with the following chemical properties:

* **Name:** 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone
* **Molecular Formula:** C₁₅H₁₀O₅
* **Molecular Weight:** 270.24 g/mol
* **Structure:** It consists of an anthraquinone core (a two-fused benzene ring system with a quinone functional group) with three hydroxyl (-OH) groups at positions 1, 3, and 6, and a methyl group (-CH₃) at position 2.

This specific anthraquinone derivative has been the focus of research for its potential applications in various fields, including:

**1. Anti-Cancer Activity:**

* Studies have shown that 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone exhibits significant cytotoxic activity against various cancer cell lines, including leukemia, colon cancer, and breast cancer.
* The mechanism of action is thought to involve the induction of apoptosis (programmed cell death) and inhibition of cancer cell proliferation.

**2. Anti-Inflammatory Activity:**

* This anthraquinone derivative has been found to possess anti-inflammatory properties, potentially acting by inhibiting the production of pro-inflammatory mediators like cytokines.
* This could make it a potential therapeutic agent for treating inflammatory diseases like arthritis and inflammatory bowel disease.

**3. Antioxidant Activity:**

* Anthraquinone derivatives are known for their antioxidant properties, and this specific compound is no exception.
* Its antioxidant activity could be beneficial in protecting cells from damage caused by free radicals, potentially reducing the risk of certain diseases.

**4. Dyeing Applications:**

* Anthraquinones are widely used as dyes in various industries. This specific compound could be investigated for its dyeing properties and potential applications in textiles and other materials.

**5. Pharmaceutical Applications:**

* The diverse biological activities of this anthraquinone derivative make it a promising candidate for further research and development of new pharmaceuticals.

**Research Importance:**

The diverse biological activities of 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone make it a valuable target for research in various fields.

* **Drug discovery:** Investigating its mechanism of action and optimizing its structure could lead to the development of new drugs for cancer treatment, inflammation, and other diseases.
* **Materials science:** Its properties could be utilized in developing novel materials with specific applications, such as dyes, pigments, and antioxidants.
* **Understanding biological processes:** Studying this compound's interactions with biological systems can provide insights into cellular processes and contribute to a better understanding of disease development.

While promising, further research is necessary to fully understand the safety, efficacy, and optimal applications of this anthraquinone derivative.

2-methyl-1,3,6-trihydroxy-9,10-anthraquinone: anthraquinone derivative [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

1,3,6-trihydroxy-2-methyl-9,10-anthraquinone : A trihydroxyanthraquinone that is 9,10-anthraquinone substituted by hydroxy groups at positions 1, 3 and 6 and a methyl group at position 2. It has been isolated from the roots of Rubia yunnanensis. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

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