A hydroxy monocarboxylic acid that has a hydroxy group beta to the carboxy group.
ChEBI ID: 35969
| Member | Definition | Role |
|---|---|---|
| 3-hydroxy-3-methyl-hexanoic acid | A 3-hydroxy monocarboxylic acid that is hexanoic acid substituted by a hydroxy group and a methyl group at position 3. It is a metabolite found in human sweat. | 3-hydroxy-3-methylhexanoic acid |
| 3-hydroxybutyric acid | A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics. | 3-hydroxybutyric acid |
| 3-hydroxyhexanoic acid | 3-hydroxyhexanoic acid | |
| 3-hydroxyisobutyric acid | A 4-carbon, branched hydroxy fatty acid and intermediate in the metabolism of valine. | 3-hydroxyisobutyric acid |
| 3-hydroxyoctanoic acid | An 8-carbon, beta-hydroxy fatty acid which may be a marker for primary defects of beta-hydroxy fatty acid metabolism. Repeating unit of poly(3-hydroxyoctanoic acid), a biopolymer used by numerous bacterial species as carbon and energy reserves. | 3-hydroxyoctanoic acid |
| 4-amino-3-hydroxybutyric acid | A gamma-amino acid comprising 4-aminobutyric acid having a 2-hydroxy substituent. | gamma-amino-beta-hydroxybutyric acid zwitterion; gamma-amino-beta-hydroxybutyric acid |
| alpha-methyl-beta-hydroxybutyrate | A 3-hydroxy monocarboxylic acid that is butyric acid which is substituted by a methyl group and a hydroxy group at positions 2 and 3, respectively. | 3-hydroxy-2-methylbutanoic acid |
| bcx 1812 | A member of the class of guanidines that is used (as its trihydrate) for the treatment of acute uncomplicated influenza in patients 18 years and older who have been symptomatic for no more than two days. | peramivir |
| beta-hydroxyisovaleric acid | A 3-hydroxy monocarboxylic acid that is isovaleric acid substituted at position 3 by a hydroxy group. Used as indicator of biotin deficiency. | 3-hydroxyisovaleric acid |
| beta-hydroxymyristic acid | A 3-hydroxy fatty acid that is tetradecanoic (myristic) acid substituted at position 3 by a hydroxy group | 3-hydroxytetradecanoic acid |
| hydracrylic acid | A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group. | 3-hydroxypropionic acid |
| hydroxypyruvic acid | A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism. | 3-hydroxypyruvic acid |
| mevaldic acid | mevaldic acid | |
| tropic acid | A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a phenyl group, and one of the methyl hydrogens is substituted by a hydroxy group. | tropic acid |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 922 (16.79) | 18.7374 |
| 1990's | 864 (15.74) | 18.2507 |
| 2000's | 1,003 (18.27) | 29.6817 |
| 2010's | 1,817 (33.10) | 24.3611 |
| 2020's | 884 (16.10) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 562 (9.78%) | 5.53% |
| Reviews | 229 (3.99%) | 6.00% |
| Case Studies | 153 (2.66%) | 4.05% |
| Observational | 23 (0.40%) | 0.25% |
| Other | 4,778 (83.17%) | 84.16% |