Arachnoid Membrane Inflammation

Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)

Synonym
Arachnoiditis
Arachnoid Membrane Inflammation
Inflammation, Arachnoid Membrane

Excerpt	Reference
"The risk of arachnoiditis is probably minimized by the use of reduced volumes and concentrations of water-soluble media."	( Correa-Paz, F; Haughton, VM; Ho, KC; Larson, SJ; Unger, GF, 1977)
"Arachnoiditis is suspected when the earliest images show a sharp decrease of tracer concentration."	( Delcourt, E; Ermans, AM; Jeghers, O, 1980)
"Spinal arachnoiditis is a disease characterized by inflammation and scarring of the arachnoid membrane of the spinal cord."	( Bai, Y; Dong, A; Lu, J; Zhang, P; Zuo, C, 2014)
"Spinal arachnoiditis is under-recognized, since diagnosis is difficult with concomitant central nervous system (CNS) pathology."	( Bennett, JE; Bielekova, B; Browne, SK; Fries, BC; Hammoud, DA; Khan, O; Komori, M; Kosa, P; Lin, YC; Panackal, AA; Ramaprasad, C; Romm, E; Rosen, LB; Williamson, PR, 2017)

Excerpt	Reference
"Adhesive arachnoiditis has not yet been reported after the use of the nonionic water-soluble contrast medium metrizamide (Amipaque)."	( Skalpe, IO, 1978)
"Arachnoiditis has been reported in patients who had received previous epidural injections of anesthetic agents."	( Haughton, VM; Ho, KC; Nguyen, C, 1991)
"Post laminectomy arachnoiditis has been shown by experiments with rats and post operative radiological imaging in humans."	( Akyurek, N; Aydın, C; Cemil, B; Ceviker, N; Erdogan, B; Kurt, G, 2011)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	199 (68.62)	23.3326
1990's	41 (14.14)	12.5806
2000's	20 (6.90)	18.1394
2010's	25 (8.62)	28.8240
2020's	5 (1.72)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	medium	4	1
lactic acid	low	1	0
dimethyl sulfoxide	low	1	0
glycerol	low	1	0
iodine	low	7	0
melatonin	low	2	0
nitrous oxide	low	1	0
sulfites	low	1	0
hydroxyindoleacetic acid	low	2	0
acetazolamide	low	1	0
baclofen	low	2	0
bupivacaine	low	6	0
caffeine	low	1	0
carbamazepine	low	2	0
chloroquine	low	1	0
clonidine	low	1	0
diazepam	low	1	0
dibucaine	low	1	0
pentetic acid	low	8	0
erythrosine	low	1	0
fentanyl	low	1	0
fluconazole	low	3	0
flucytosine	low	3	0
gabapentin	medium	3	1
gentamicin	low	1	0
lidocaine	low	5	0
indomethacin	low	1	0
iothalamic acid	low	20	0
isoniazid	low	3	0
ketoconazole	low	1	0
metyrapone	low	1	0
miconazole	low	1	0
nitroglycerin	low	1	0
aminosalicylic acid	low	2	0
praziquantel	low	4	0
procaine	low	1	0
thalidomide	low	1	0
prednisolone	medium	8	2
sorbitol	low	6	0
penicillamine	medium	1	1
norethandrolone	low	1	0
prednisone	low	9	0
paramethasone	low	1	0
methylprednisolone acetate	low	7	0
glutamine	low	1	0
kanamycin a	low	1	0
edetic acid	low	1	0
methicillin	low	1	0
desoxycorticosterone	low	1	0
barbituric acid	low	1	0
triamcinolone diacetate	low	1	0
ampicillin	low	1	0
cytarabine	medium	3	1
medroxyprogesterone acetate	low	1	0
triamcinolone acetonide	low	1	0
methylprednisolone	low	24	0
diatrizoate meglumine	low	2	0
meglumine	low	6	0
chloroprocaine	low	1	0
1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt	low	7	0
thiamine pyrophosphate	low	1	0
evans blue	low	3	0
betamethasone	low	1	0
gentian violet	low	1	0
diphenylamine	low	1	0
ethambutol	low	1	0
thorium dioxide	low	6	0
methylprednisolone hemisuccinate	low	1	0
fluorescein-5-isothiocyanate	low	1	0
streptomycin	low	6	0
triamcinolone hexacetonide	low	1	0
lanthanum	low	1	0
technetium	low	7	0
chromium	low	1	0
gadolinium	low	4	0
xenon	low	2	0
ytterbium	low	2	0
ozone	low	1	0
trolamine salicylate	low	1	0
iocarmic acid	low	1	0
iodine	low	1	0
phenyl acetate	medium	2	1
triamcinolone	low	4	0
transferrin	low	1	0
substance p	low	1	0
quisqualic acid	low	2	0
enkephalin, methionine	low	1	0
propiconazole	low	1	0
fomesafen	low	1	0
itraconazole	low	2	0
chloroquine diphosphate	low	1	0
iopamidol	low	2	0
fluorodeoxyglucose f18	low	1	0
levobupivacaine	low	1	0
methotrexate	medium	10	1
metabisulfite	low	1	0
technetium tc 99m pentetate	low	1	0
cortisone	low	6	0
fibrin	low	2	0
glucosamine	low	1	0
fructans	low	1	0
cefoxitin	low	1	0
metrizamide	medium	34	2
tacrolimus	low	1	0
bromochloroacetic acid	low	1	0
iothalamate meglumine	low	18	0
quinine	low	1	0
alprostadil	medium	1	1
amphotericin b	low	11	0
iodopyracet	low	1	0
oxymorphone	low	1	0
morphine	low	10	0
indium	low	1	0
phosphorus	low	1	0
gadolinium dtpa	medium	8	1
chlorhexidine	low	2	0
mocetinostat	low	1	0
nystatin a1	low	1	0
pituitrin	low	1	0
beta-endorphin	low	2	0
ziconotide	low	2	0
iocarmate meglumine	low	3	0
sodium pertechnetate tc 99m	low	3	0
interleukin-8	low	1	0
minocycline	low	1	0
piroxicam	low	1	0
mobiflex	low	1	0
tigecycline	low	1	0
kaolinite	low	9	0
hyaluronoglucosaminidase	medium	10	1
vitamin b 12	low	1	0
chondroitin sulfates	low	1	0
eye	low	6	0

Protein Targets (1,051)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	12	0	0	12
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	10	0	0	10
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
thioredoxin reductase	21	0	0	21
GALC protein	6	0	0	6
GLI family zinc finger 3	34	0	0	34
nuclear receptor subfamily 1, group I, member 3	25	0	0	25
cytochrome P450 family 3 subfamily A polypeptide 4	29	0	0	29
glucocorticoid receptor [Homo sapiens]	36	0	0	36
retinoic acid nuclear receptor alpha variant 1	34	0	0	34
retinoid X nuclear receptor alpha	26	0	0	26
estrogen-related nuclear receptor alpha	31	0	0	31
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	13	0	0	13
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	44	0	0	44
Bloom syndrome protein isoform 1	16	0	0	16
thyroid hormone receptor beta isoform a	14	0	0	14
nuclear factor erythroid 2-related factor 2 isoform 1	32	0	0	32
geminin	35	0	0	35
peripheral myelin protein 22	15	0	0	15
survival motor neuron protein isoform d	9	0	0	9
muscleblind-like protein 1 isoform 1	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	18	5	1	24
ATP-binding cassette sub-family C member 3	0	35	0	35
Multidrug resistance-associated protein 4	0	35	0	37
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	2	1	6
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	49	0	49
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	3	0	3
Carbonic anhydrase 1	0	7	1	14
Carbonic anhydrase 2	0	7	2	14
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	6	0	6
Carbonic anhydrase 3	0	2	1	6
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	16	1	18
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	3	0	4
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	4	0	4
Cytochrome P450 2D6	0	12	0	12
Cytochrome P450 2A6	0	2	0	2
Cytochrome P450 2C9	0	10	1	11
5-hydroxytryptamine receptor 2A	0	4	0	4
Androgen receptor	0	10	0	10
Gamma-aminobutyric acid receptor subunit beta-1	18	5	1	24
Translocator protein	0	3	2	6
Gamma-aminobutyric acid receptor subunit delta	18	5	1	24
Gamma-aminobutyric acid receptor subunit gamma-2	18	5	3	26
Gamma-aminobutyric acid receptor subunit alpha-5	18	5	1	24
Gamma-aminobutyric acid receptor subunit alpha-3	18	5	1	24
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	1	2	3
Carbonic anhydrase 4	0	3	1	6
Carbonic anhydrase 6	0	2	1	5
Gamma-aminobutyric acid receptor subunit gamma-1	18	5	1	24
Gamma-aminobutyric acid receptor subunit alpha-2	18	5	1	24
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	4	0	5
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	18	5	1	24
Gamma-aminobutyric acid receptor subunit gamma-3	18	5	1	24
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	18	5	1	24
Adenosine receptor A2a	0	4	1	7
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Delta-type opioid receptor	0	6	0	7
Cytochrome P450 2C19	0	6	0	6
Delta-type opioid receptor	0	7	2	10
Mu-type opioid receptor	0	8	3	14
Carbonic anhydrase 5A, mitochondrial	0	2	1	6
Carbonic anhydrase	0	2	0	3
Kappa-type opioid receptor	0	6	0	6
Carbonic anhydrase 7	0	2	1	5
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	1	1	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	2
D(2) dopamine receptor	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-1	18	5	3	26
Gamma-aminobutyric acid receptor subunit beta-3	18	5	1	24
Gamma-aminobutyric acid receptor subunit beta-2	18	5	3	26
Cholinesterase	0	3	0	3
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	7	0	7
Fatty-acid amide hydrolase 1	1	1	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	4	0	5
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase 9	0	2	1	6
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	2
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	4
GABA theta subunit	18	5	1	24
Canalicular multispecific organic anion transporter 1	0	34	0	34
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase 15	0	2	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	2	0	4
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	18	5	1	24
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	2	1	6
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	1	6
TDP1 protein	32	0	0	32
AR protein	50	0	0	50
estrogen nuclear receptor alpha	52	0	0	52
peroxisome proliferator activated receptor gamma	19	0	0	19
Cellular tumor antigen p53	27	0	0	27
Thromboxane-A synthase	0	4	0	4
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
Microtubule-associated protein tau	11	0	0	12
thioredoxin glutathione reductase	7	0	0	7
Smad3	5	0	0	5
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	1	2
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
Chain A, Cruzipain	9	0	0	9
interleukin 8	6	0	0	6
phosphopantetheinyl transferase	19	0	0	19
GLS protein	13	0	0	13
farnesoid X nuclear receptor	16	0	0	16
peroxisome proliferator-activated receptor delta	16	0	0	16
vitamin D (1,25- dihydroxyvitamin D3) receptor	27	0	0	27
tumor necrosis factor	2	0	0	2
vitamin D3 receptor isoform VDRA	12	0	0	12
lamin isoform A-delta10	32	0	0	32
Nuclear receptor ROR-gamma	9	0	0	9
Potassium voltage-gated channel subfamily H member 2	0	11	0	11
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	5
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	20	0	0	20
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Beta-lactamase	0	1	0	2
acid sphingomyelinase	3	0	0	3
apical membrane antigen 1, AMA1	2	0	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
chromobox protein homolog 1	20	0	0	20
thyroid hormone receptor beta isoform 2	29	0	0	29
DNA polymerase beta	3	0	0	3
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	11	0	0	11
DNA polymerase kappa isoform 1	11	0	0	11
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	16	1	1	18
10 kDa heat shock protein, mitochondrial	0	4	0	4
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	1	0	1
Thiosulfate sulfurtransferase	0	4	0	4
Metallo-beta-lactamase VIM-13	0	1	0	2
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	4	0	4
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	4	0	4
Metallo-b-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	1	0	2
ATP-dependent phosphofructokinase	17	0	0	17
ATAD5 protein, partial	15	0	0	15
NFKB1 protein, partial	6	0	0	6
regulator of G-protein signaling 4	12	0	0	12
67.9K protein	7	0	0	7
activating transcription factor 6	10	0	0	10
D(1A) dopamine receptor	3	0	0	3
cytochrome P450 3A4 isoform 1	18	0	0	18
histone acetyltransferase KAT2A isoform 1	9	0	0	9
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Polyphenol oxidase 2	0	2	0	2
glp-1 receptor, partial	8	0	0	8
RAR-related orphan receptor gamma	34	0	0	34
USP1 protein, partial	18	0	0	18
G	16	0	0	16
aryl hydrocarbon receptor	18	0	0	18
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	26	0	0	26
thyroid stimulating hormone receptor	13	0	0	13
nuclear receptor ROR-gamma isoform 1	14	0	0	14
Voltage-dependent calcium channel gamma-2 subunit	20	0	0	20
Interferon beta	21	0	0	21
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
Glutamate receptor 2	20	1	0	21
TAR DNA-binding protein 43	11	0	0	11
Inositol hexakisphosphate kinase 1	16	0	0	16
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	16	0	0	16
cytochrome P450 2C9, partial	16	0	0	16
pregnane X receptor	7	0	0	7
progesterone receptor	22	0	0	22
pregnane X nuclear receptor	29	0	0	29
IDH1	14	0	0	14
nuclear receptor subfamily 1, group I, member 2	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 2	14	0	0	14
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	16	3	24
Glycine receptor subunit alpha-1	0	16	0	16
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
ORF73	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	21	0	0	21
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Inositol monophosphatase 1	4	0	0	4
Solute carrier organic anion transporter family member 1B3	0	6	0	9
Solute carrier organic anion transporter family member 1B1	0	7	0	9
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	2	4
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Ferritin light chain	7	0	0	7
Luciferase	13	0	0	13
Fumarate hydratase	6	0	0	6
thyroid stimulating hormone receptor	14	0	0	14
estrogen receptor 2 (ER beta)	14	0	0	14
cytochrome P450 2D6	16	0	0	16
polyprotein	6	0	0	6
cytochrome P450 2C19 precursor	6	0	0	6
cytochrome P450 2C9 precursor	8	0	0	8
transcriptional regulator ERG isoform 3	6	0	0	6
Histamine H2 receptor	14	0	0	14
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
muscarinic acetylcholine receptor M1	12	0	0	12
lethal factor (plasmid)	3	0	0	3
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Adenosine receptor A3	0	5	0	5
Replicase polyprotein 1ab	0	2	1	3
Amine oxidase [flavin-containing] A	0	3	0	3
Acetylcholinesterase	0	5	0	5
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	6	1	8
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	1	4
Adenosine receptor A1	0	3	1	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	3	0	3
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	1	0	1
acetylcholinesterase	11	0	0	11
mitogen-activated protein kinase 1	7	0	0	7
Vpr	2	0	0	2
Bile salt export pump	0	9	0	9
Albumin	0	0	3	3
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	0	0	2
Sodium channel protein type 4 subunit alpha	0	3	0	4
Cytochrome P450 2J2	0	6	0	6
Sodium channel protein type 9 subunit alpha	0	3	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
PAX8	0	0	0	1
15-lipoxygenase, partial	6	0	0	6
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
SMAD family member 2	11	0	0	11
SMAD family member 3	11	0	0	11
caspase 7, apoptosis-related cysteine protease	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
PINK1	2	0	0	2
glucocerebrosidase	3	0	0	3
Parkin	4	0	0	4
heat shock protein 90	0	0	2	2
caspase-3	3	0	0	3
calcineurin A1, putative	0	0	2	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
Histone H2A.x	9	0	0	9
cytochrome P450 2D6 isoform 1	11	0	0	11
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
cellular tumor antigen p53 isoform a	5	0	0	5
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	10	0	0	10
heat shock protein beta-1	9	0	0	9
huntingtin isoform 2	2	0	0	2
importin subunit beta-1 isoform 1	4	0	0	4
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
flap endonuclease 1	9	0	0	9
protein AF-9 isoform a	0	0	0	1
snurportin-1	4	0	0	4
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	1
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
bcl-2-related protein A1	0	1	0	1
urokinase plasminogen activator surface receptor precursor	6	0	0	6
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	2	2
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 1	0	10	0	12
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	0	0	8
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	3	0	3
Glutathione reductase, mitochondrial	0	1	0	2
Integrin beta-3	4	0	0	4
72 kDa type IV collagenase	0	1	0	1
Integrin alpha-IIb	4	0	0	4
Matrix metalloproteinase-9	0	2	0	2
Trypanothione reductase	0	1	0	1
Alpha-synuclein	3	1	0	4
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Multidrug and toxin extrusion protein 1	0	5	0	5
Spermine oxidase	0	1	0	1
PPM1D protein	5	0	0	5
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	1	2
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Amyloid-beta precursor protein	0	2	0	2
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	2	1	3
Muscarinic acetylcholine receptor M2	0	7	0	7
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M5	0	3	0	3
Alpha-2A adrenergic receptor	0	11	2	13
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	5	0	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	0	3
Alpha-2B adrenergic receptor	0	9	1	10
Alpha-2C adrenergic receptor	0	5	1	6
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	5	0	5
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
Angiotensin-converting enzyme 2	0	1	1	2
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
endonuclease IV	6	0	0	6
Beta-1 adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Alpha-1B adrenergic receptor	0	6	0	6
Alpha-1A adrenergic receptor	0	0	1	1
D	0	2	0	2
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	7	1	8
Alpha-2B adrenergic receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	3	0	3
Alpha-2A adrenergic receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	6	1	7
D(1B) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	6	0	6
Alpha-2B adrenergic receptor	0	0	0	1
D(4) dopamine receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	7	1	8
5-hydroxytryptamine receptor 7	0	4	0	4
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	3	0	4
Nischarin	0	1	0	1
dopamine D1 receptor	3	0	0	3
peripheral myelin protein 22 isoform 1	8	0	0	8
M-phase phosphoprotein 8	10	0	0	10
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	3	0	3
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
EWS/FLI fusion protein	15	0	0	15
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 2	0	3	0	3
Hsf1 protein	0	0	2	2
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	1	6	8
ATP-dependent translocase ABCB1	0	10	0	12
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	2	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	3	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	2	5
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	3	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Cereblon isoform 4	0	4	0	4
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	4	1	6
ClpP	4	0	0	4
Glycoprotein hormones alpha chain	1	0	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	2
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
hypothetical protein, conserved	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
thyrotropin-releasing hormone receptor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
eyes absent homolog 2 isoform a	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Pantothenate synthetase	0	2	0	2
Luciferin 4-monooxygenase	0	1	0	1
60 kDa chaperonin	0	2	0	2
Nuclear factor NF-kappa-B p105 subunit	0	0	0	1
Tyrosine-protein phosphatase 1	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Vesicular glutamate transporter 3	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
D(2) dopamine receptor	0	7	0	7
D(4) dopamine receptor	0	3	0	3
Kappa-type opioid receptor	0	5	2	8
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	9	3	13
D(3) dopamine receptor	0	7	0	7
Delta-type opioid receptor	0	9	1	11
Kappa-type opioid receptor	0	9	1	11
Mu-type opioid receptor	0	4	1	7
Sigma non-opioid intracellular receptor 1	0	1	0	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	3
Histone deacetylase 3	0	4	0	4
Rap guanine nucleotide exchange factor 3	3	0	0	3
Chymotrypsinogen A	0	3	0	3
Beta-lactamase	0	3	0	3
Steroid 17-alpha-hydroxylase/17,20 lyase	0	5	0	5
Heme oxygenase 1	0	2	0	2
ATP-dependent translocase ABCB1	0	6	0	6
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	6	0	6
Cytochrome P450 11B1, mitochondrial	0	3	0	3
Cytochrome P450 11B2, mitochondrial	0	3	0	3
ATP-dependent translocase ABCB1	0	6	0	6
Heme oxygenase 2	0	2	0	2
Malate dehydrogenase, cytoplasmic	0	3	0	3
Histone deacetylase 4	0	3	0	3
Cytochrome P450 144	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Mycocyclosin synthase	0	0	2	2
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	2	2
Histone deacetylase 1	0	4	0	4
Lanosterol 14-alpha demethylase	0	5	2	7
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	3	0	3
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	3	0	3
heat shock protein 90, putative	0	0	0	3
likely tRNA 2'-phosphotransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	7	0	0	7
serine/threonine-protein kinase PLK1	2	0	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
neuropeptide S receptor isoform A	5	0	0	5
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
alpha synuclein, partial	1	0	0	1
luciferase	1	0	0	1
Caspase-7	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	2	0	0	2
Epidermal growth factor receptor	0	3	0	3
Tyrosine-protein kinase Fyn	0	2	0	2
Substance-K receptor	0	8	0	8
D(1A) dopamine receptor	0	4	0	4
Glutamate receptor ionotropic, kainate 1	1	2	0	3
Histamine H2 receptor	0	8	0	8
5-hydroxytryptamine receptor 2A	0	6	0	6
Glutamate receptor ionotropic, kainate 2	1	2	0	3
Glutamate receptor ionotropic, kainate 3	1	2	0	3
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Glutamate receptor ionotropic, kainate 4	1	1	0	2
Sodium-dependent dopamine transporter	0	6	0	6
Leukotriene B4 receptor 1	1	0	0	1
Glutamate receptor ionotropic, kainate 5	1	1	0	2
Leukotriene B4 receptor 2	1	0	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Solute carrier family 22 member 8	0	0	0	1
alpha-galactosidase	2	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	3	0	3
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
ras-related protein Rab-9A	2	0	0	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	5
Interleukin-8	0	1	0	1
Androgen receptor	0	4	3	7
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Sodium-dependent dopamine transporter	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	1	0	2
Nitric oxide synthase, inducible	0	1	0	1
Substance-P receptor	0	3	0	3
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	5	1	6
Prostaglandin G/H synthase 2	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	3	0	3
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Guanine nucleotide-binding protein G	3	0	0	3
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
Solute carrier family 22 member 6	0	3	0	4
Solute carrier family 22 member 7	0	0	0	1
Rho-associated protein kinase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	4	0	4
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Acetylcholinesterase	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	3	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	4
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	3	0	4
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	4
Glutamate receptor ionotropic, NMDA 3A	0	3	0	4
Estrogen receptor beta	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Epoxide hydrolase 1	0	0	0	2
Aldo-keto reductase family 1 member B1	0	4	0	4
Cytochrome P450 2C11	0	2	0	2
Steroid 21-hydroxylase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	4
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	3	0	3
Cytochrome P450 7A1	0	1	0	1
Estrogen receptor	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	4	0	4
Gonadotropin-releasing hormone receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	4	0	4
Type-1 angiotensin II receptor	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Estrogen receptor	0	3	1	4
Progesterone receptor	0	4	1	6
Mineralocorticoid receptor	0	3	1	4
Androgen receptor	0	0	1	1
Estrogen receptor beta	0	3	1	4
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 1A2	0	2	0	2
Metabotropic glutamate receptor 1	0	2	1	3
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Cytochrome P450 1B1	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	2	3
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	1	0	2
Protein-arginine deiminase type-4	0	5	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
5-hydroxytryptamine receptor 3E	0	0	1	1
5-hydroxytryptamine receptor 4	0	4	0	4
5-hydroxytryptamine receptor 3B	0	0	1	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 2C	0	4	0	4
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	4	0	4
5-hydroxytryptamine receptor 3A	0	0	1	1
Lactoperoxidase	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	2
5-hydroxytryptamine receptor 3D	0	0	1	1
5-hydroxytryptamine receptor 3C	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Metabotropic glutamate receptor 6	0	2	0	2
Cytochrome P450 1A2	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Beta-1 adrenergic receptor	0	2	0	2
Beta-3 adrenergic receptor	0	2	0	2
Cannabinoid receptor 1	0	2	0	2
Aromatase	0	0	1	1
Substance-P receptor	0	4	1	5
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
methionyl-tRNA synthetase, putative	0	1	0	1
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Mu-type opioid receptor	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
luciferase	0	0	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Solute carrier family 22 member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Cytochrome P450 2D4	0	1	0	1
Chain A, Glutamate Receptor 2	0	1	0	1
Chain A, Glutamate Receptor 2	0	1	0	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	0	1	1
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Metabotropic glutamate receptor 5	0	1	1	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate carboxypeptidase 2	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	1	1	2
Metabotropic glutamate receptor 7	0	0	1	1
Metabotropic glutamate receptor 3	0	1	0	1
Metabotropic glutamate receptor 4	0	1	1	2
Cystine/glutamate transporter	0	1	0	1
Glutamate receptor 4	0	1	0	1
Glutamate receptor 3	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Cytochrome P450 3A5	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Arachnoid Membrane Inflammation

Synonyms(3)

Research Excerpts

Overview

Context

Research

Studies (290)

Protein Targets (1,051)

Arachnoid Membrane Inflammation

Synonyms(3)

Research Excerpts

Overview

Context

Research

Studies (290)

Drugs Studied (150)

Protein Targets (1,051)