Dandy-Walker Complex

A congenital abnormality of the central nervous system marked by failure of the midline structures of the cerebellum to develop, dilation of the fourth ventricle, and upward displacement of the transverse sinuses, tentorium, and torcula. Clinical features include occipital bossing, progressive head enlargement, bulging of anterior fontanelle, papilledema, ataxia, gait disturbances, nystagmus, and intellectual compromise. (From Menkes, Textbook of Child Neurology, 5th ed, pp294-5)

Synonyms(9)

Synonym
Dandy-Walker Cyst
Hydrocephalus, Internal, Dandy-Walker Type
Dandy-Walker Deformity
Dandy-Walker Syndrome
Luschka-Magendie Foramina Atresia
Dandy-Walker Malformation
Dandy-Walker Syndrome, Familial
Hydrocephalus, Noncommunicating, Dandy-Walker Type
Dandy-Walker Complex

Research

Studies (63)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	18 (28.57)	23.3326
1990's	16 (25.40)	12.5806
2000's	17 (26.98)	18.1394
2010's	9 (14.29)	28.8240
2020's	3 (4.76)	9.53

Drug	Relationship Strength	Studies
gamma-aminobutyric acid	low	1
salicylic acid	low	4
niacinamide	low	1
pteridines	low	3
uric acid	low	1
phenytoin	low	1
citalopram	low	1
valproic acid	low	1
gentamicin	low	1
iohexol	low	1
apnea	low	3
nevirapine	low	1
sevoflurane	low	1
thyroxine	low	2
penicillin g	low	1
triiodothyronine	low	1
glutamine	low	1
cephalothin	low	1
levodopa	low	1
methicillin	low	1
ampicillin	low	1
triamcinolone acetonide	low	1
6-aminonicotinamide	low	2
vancomycin	low	2
stavudine	low	1
molybdenum	low	1
technetium	low	7
ytterbium	low	1
etoposide	low	1
fomesafen	low	1
lamivudine	low	1
efavirenz	low	2
trimethoprim, sulfamethoxazole drug combination	low	1
inositol 3-phosphate	low	1
enclomiphene	low	1
cholecalciferol	low	1
phenylephrine hydrochloride	low	2
deamino arginine vasopressin	low	1
sulfur	low	1
paliperidone palmitate	low	1
pituitrin	low	1
calpain	low	1
quetiapine fumarate	low	1
trelstar	low	1
warfarin	low	3
thromboplastin	low	1
molybdenum cofactor	low	3
eye	low	3

Protein Targets (709)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
glp-1 receptor, partial	5	0	0	5
RAR-related orphan receptor gamma	9	0	0	9
TDP1 protein	13	0	0	13
AR protein	14	0	0	14
estrogen receptor 2 (ER beta)	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	9	0	0	9
retinoic acid nuclear receptor alpha variant 1	11	0	0	11
retinoid X nuclear receptor alpha	10	0	0	10
estrogen-related nuclear receptor alpha	16	0	0	16
estrogen nuclear receptor alpha	22	0	0	22
IDH1	7	0	0	7
chromobox protein homolog 1	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 2	5	0	0	5
geminin	21	0	0	21
survival motor neuron protein isoform d	4	0	0	4
Voltage-dependent calcium channel gamma-2 subunit	3	0	0	3
Glutamate receptor 2	3	0	0	3
Nicotinamide N-methyltransferase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	5	0	0	5
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	7	0	0	7
Chain A, 2-oxoglutarate Oxygenase	6	0	0	6
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Cruzipain	2	0	0	2
Beta-lactamase	0	0	0	3
acid sphingomyelinase	1	0	0	1
GLS protein	9	0	0	9
GLI family zinc finger 3	11	0	0	11
apical membrane antigen 1, AMA1	4	0	0	4
farnesoid X nuclear receptor	7	0	0	7
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	0	3
Metallo-beta-lactamase VIM-11	0	0	0	3
euchromatic histone-lysine N-methyltransferase 2	18	0	0	18
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
thyroid hormone receptor beta isoform 2	10	0	0	10
DNA polymerase beta	4	0	0	4
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	4	0	0	4
DNA polymerase kappa isoform 1	6	0	0	6
Carbonic anhydrase 1	0	3	0	5
Carbonic anhydrase 2	0	3	0	5
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	5	0	5
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	11	0	0	11
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	3	0	3
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	0	0	3
Efflux transporter	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	3
Beta-lactamase	0	0	0	3
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	3	0	3
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	3	0	3
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	3
Histamine H3 receptor	0	0	0	3
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	0	0	3
ATP-dependent phosphofructokinase	7	0	0	7
thioredoxin reductase	12	0	0	12
ATAD5 protein, partial	7	0	0	7
Microtubule-associated protein tau	5	0	0	5
arylsulfatase A	7	0	0	7
Bloom syndrome protein isoform 1	9	0	0	9
D(1A) dopamine receptor	4	0	0	4
lamin isoform A-delta10	15	0	0	15
neuropeptide S receptor isoform A	4	0	0	4
glucocorticoid receptor [Homo sapiens]	15	0	0	15
pregnane X nuclear receptor	13	0	0	13
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	2	0	2
ATP-binding cassette sub-family C member 3	0	16	0	16
Multidrug resistance-associated protein 4	0	16	0	16
5-hydroxytryptamine receptor 4	0	10	0	10
Bile salt export pump	0	24	0	24
Muscarinic acetylcholine receptor M2	0	7	1	11
Muscarinic acetylcholine receptor M4	0	8	1	11
Muscarinic acetylcholine receptor M1	0	3	1	6
Muscarinic acetylcholine receptor M3	0	3	1	6
Muscarinic acetylcholine receptor M4	0	3	1	6
Muscarinic acetylcholine receptor M5	0	3	1	6
Muscarinic acetylcholine receptor M5	0	8	1	11
Muscarinic acetylcholine receptor M2	0	3	1	7
Muscarinic acetylcholine receptor M1	0	7	2	12
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	8	1	11
Alpha-1D adrenergic receptor	0	6	0	6
5-hydroxytryptamine receptor 2C	0	10	0	10
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	1	0	0	3
5-hydroxytryptamine receptor 7	0	2	0	2
Reverse transcriptase/RNaseH	0	5	4	20
Muscarinic acetylcholine receptor	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	17	0	18
phosphopantetheinyl transferase	5	0	0	5
NFKB1 protein, partial	2	0	0	2
regulator of G-protein signaling 4	4	0	0	4
67.9K protein	3	0	0	3
activating transcription factor 6	3	0	0	3
cytochrome P450 3A4 isoform 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	2	3	1	7
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	2	3	1	7
Gamma-aminobutyric acid receptor subunit delta	2	3	1	7
Gamma-aminobutyric acid receptor subunit gamma-2	2	3	3	9
Gamma-aminobutyric acid receptor subunit alpha-5	2	3	1	7
Gamma-aminobutyric acid receptor subunit alpha-3	2	3	1	7
Gamma-aminobutyric acid receptor subunit gamma-1	2	3	1	7
Gamma-aminobutyric acid receptor subunit alpha-2	2	3	1	7
Gamma-aminobutyric acid receptor subunit alpha-4	2	3	1	7
Gamma-aminobutyric acid receptor subunit gamma-3	2	3	1	7
Gamma-aminobutyric acid receptor subunit alpha-6	2	3	1	7
Gamma-aminobutyric acid receptor subunit alpha-1	2	3	3	9
Gamma-aminobutyric acid receptor subunit beta-3	2	3	1	7
Gamma-aminobutyric acid receptor subunit beta-2	2	3	3	9
GABA theta subunit	2	3	1	7
Gamma-aminobutyric acid receptor subunit epsilon	2	3	1	7
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
acetylcholinesterase	1	0	0	1
USP1 protein, partial	7	0	0	7
thyroid stimulating hormone receptor	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	7	0	0	7
thyroid hormone receptor beta isoform a	9	0	0	9
mitogen-activated protein kinase 1	4	0	0	4
Vpr	2	0	0	2
Bile salt export pump	0	4	0	4
Albumin	0	0	3	3
Major prion protein	0	0	1	1
Cellular tumor antigen p53	14	0	0	14
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	9	0	9
UDP-glucuronosyltransferase 2B7	0	1	0	4
Cytochrome P450 2B6	0	0	1	2
Sodium channel protein type 4 subunit alpha	0	2	0	4
Cytochrome P450 2J2	0	4	0	4
Potassium voltage-gated channel subfamily H member 2	0	8	0	8
Sodium channel protein type 9 subunit alpha	0	3	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
endonuclease IV	3	0	0	3
WRN	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
vitamin D3 receptor isoform VDRA	4	0	0	4
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
heat shock protein beta-1	4	0	0	4
importin subunit beta-1 isoform 1	5	0	0	5
flap endonuclease 1	6	0	0	6
serine/threonine-protein kinase PLK1	2	0	0	2
snurportin-1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	12	0	0	12
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Solute carrier family 22 member 6	0	4	0	4
Solute carrier family 22 member 8	0	3	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase OXA-1	0	0	0	1
Beta-lactamase	0	0	0	2
Kappa-type opioid receptor	0	4	1	7
Beta-lactamase TEM	0	1	0	3
B2 metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 6	0	3	0	4
Solute carrier family 22 member 7	0	1	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 8	0	5	0	5
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Solute carrier family 22 member 7	0	1	0	1
phosphoglycerate kinase	2	0	0	2
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
Chain A, Ferritin light chain	3	0	0	3
Luciferase	6	0	0	6
interleukin 8	2	0	0	2
15-lipoxygenase, partial	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
peroxisome proliferator-activated receptor delta	5	0	0	5
peroxisome proliferator activated receptor gamma	12	0	0	12
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
nuclear receptor ROR-gamma isoform 1	5	0	0	5
60 kDa chaperonin	0	1	0	1
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Nuclear receptor ROR-gamma	3	0	0	3
EWS/FLI fusion protein	7	0	0	7
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Aldo-keto reductase family 1 member B1	0	7	0	7
Tryptophan 5-hydroxylase 1	0	1	0	1
Angiotensin-converting enzyme	0	5	0	5
Aldo-keto reductase family 1 member B1	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	0	5
Acetylcholinesterase	0	3	0	3
Aromatase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	7	0	7
Sodium-dependent dopamine transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	6	1	7
Sodium-dependent serotonin transporter	0	2	0	2
Histamine H1 receptor	0	6	1	7
5-hydroxytryptamine receptor 2B	0	8	0	8
Sodium-dependent dopamine transporter	0	3	0	3
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	5	0	5
Ataxin-2	7	0	0	7
Sigma non-opioid intracellular receptor 1	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	2	0	2
Transporter	0	4	0	4
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Thrombopoietin	1	0	0	1
cytochrome P450 2D6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
cytochrome P450 2D6 isoform 1	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
huntingtin isoform 2	1	0	0	1
muscarinic acetylcholine receptor M1	4	0	0	4
5-hydroxytryptamine receptor 2A	0	6	0	6
Histamine H1 receptor	0	1	0	2
Histamine N-methyltransferase	0	0	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Solute carrier family 22 member 1	0	1	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Histamine H4 receptor	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain B, Pol Polyprotein	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
SMAD family member 2	3	0	0	3
PPM1D protein	2	0	0	2
SMAD family member 3	3	0	0	3
caspase 7, apoptosis-related cysteine protease	2	0	0	2
progesterone receptor	6	0	0	6
G	3	0	0	3
caspase-3	2	0	0	2
thyroid stimulating hormone receptor	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Prothrombin	0	2	0	2
Interferon beta	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	3	0	0	3
Gag-Pol polyprotein	0	4	0	4
Gag-Pol polyprotein	0	2	0	2
Acetylcholinesterase	0	0	0	2
Cannabinoid receptor 1	0	2	0	2
Microsomal triglyceride transfer protein large subunit	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	1	2	0	3
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120	0	1	0	1
Protease	0	2	0	3
Inositol hexakisphosphate kinase 1	3	0	0	3
ATPase family AAA domain-containing protein 5	5	0	0	5
Fructose-1,6-bisphosphatase 1	0	0	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Reverse transcriptase	0	2	2	4
Cholesterol 24-hydroxylase	0	0	1	1
cytochrome P450 2C9, partial	3	0	0	3
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
Smad3	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Epidermal growth factor receptor	0	3	0	3
Estrogen receptor	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Tyrosine-protein kinase Fyn	0	2	0	2
Alpha-2A adrenergic receptor	0	5	0	5
Adenosine receptor A3	0	2	0	2
Cytochrome P450 2D6	0	2	0	2
Beta-3 adrenergic receptor	0	2	0	2
Alpha-1B adrenergic receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	4	0	4
Substance-K receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
C-8 sterol isomerase	0	1	0	1
D(3) dopamine receptor	0	4	0	4
Alpha-synuclein	1	0	0	1
Alpha-1A adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 6	0	4	0	4
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
Histone H2A.x	3	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Prothrombin	0	0	1	2
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	4
Cytochrome P450 3A4	0	3	0	3
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	1	1	7
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	0	0	2
Caspase-3	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	0	0	2
Glutamate receptor ionotropic, NMDA 2B	0	0	0	2
Glutamate receptor ionotropic, NMDA 2C	0	0	0	2
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	8
Glutamate receptor ionotropic, NMDA 2D	0	0	0	2
Tubulin beta-2B chain	0	1	0	1
Integrase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	2
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Glutamate receptor ionotropic, NMDA 3A	0	0	0	2
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	3	4
transcriptional regulator ERG isoform 3	3	0	0	3
peripheral myelin protein 22	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Histone deacetylase 3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	1	4
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Histone deacetylase 4	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
TAR DNA-binding protein 43	3	0	0	3
Histone deacetylase 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Histone deacetylase 8	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Histone deacetylase 5	0	3	0	3
Chain A, Glutamine Binding Protein	0	0	1	1
peripheral myelin protein 22 isoform 1	2	0	0	2
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	1	0	1
nonstructural protein 1	1	0	0	1
aryl hydrocarbon receptor	6	0	0	6
muscleblind-like protein 1 isoform 1	2	0	0	2
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Albumin	0	2	5	7
Albumin	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cholinesterase	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Adenosine receptor A1	0	2	0	3
Caspase-1	0	1	0	1
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Caspase-4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Mu-type opioid receptor	0	3	1	4
Fatty-acid amide hydrolase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Capsid protein	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Synaptic vesicle glycoprotein 2A	0	2	0	2
dopamine D1 receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
glucokinase regulatory protein	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
M-phase phosphoprotein 8	2	0	0	2
Polyphenol oxidase 2	0	1	0	3
Carbonic anhydrase 12	0	1	0	2
Plasma kallikrein	0	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Carbonic anhydrase 3	0	1	0	2
Tyrosinase	0	1	0	1
Carbonic anhydrase 4	0	1	0	2
Carbonic anhydrase 6	0	1	0	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase 7	0	1	0	2
Carbonic anhydrase	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase 9	0	1	0	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Carbonic anhydrase 15	0	1	0	2
Carbonic anhydrase 13	0	1	0	2
Carbonic anhydrase 14	0	1	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Histidine decarboxylase	0	0	1	1
D(3) dopamine receptor	0	2	0	2
Adenosine receptor A1	0	3	0	3
Delta-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	2	4
Kappa-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	2	2	4
Kappa-type opioid receptor	0	1	2	3
Mu-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	2	5
Mu-type opioid receptor	0	1	0	2
Sigma non-opioid intracellular receptor 1	0	3	1	4
Beta-2 adrenergic receptor	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain B, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain B, Hiv-1 Reverse Transcriptase	0	1	0	1
Chain A, Reverse transcriptase/ribonuclease H	0	1	0	1
Renin	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Imidazoleglycerol-phosphate dehydratase	0	1	0	1
Ryanodine receptor 1	0	1	0	1
Exoribonuclease H	0	1	0	1
Cardiac ryanodine receptor 2	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	2	0	2
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
NAD-dependent protein deacetylase	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	1	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
D(2) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
D	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
D(2) dopamine receptor	0	2	0	2
Inositol monophosphatase 1	2	0	0	2
Transporter	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
streptokinase A precursor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
GALC protein	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Thymidine kinase 2	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
Thymidine kinase, cytosolic	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	2
Glucocorticoid receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
glucocerebrosidase	1	0	0	1
Androgen receptor	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
pregnane X receptor	1	0	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Cytochrome P450 2A6	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Dandy-Walker Complex

Synonyms(9)

Research

Studies (63)

Drugs Studied (55)

Protein Targets (709)