Compartment Syndromes

Conditions in which increased pressure within a limited space compromises the BLOOD CIRCULATION and function of tissue within that space. Some of the causes of increased pressure are TRAUMA, tight dressings, HEMORRHAGE, and exercise. Sequelae include nerve compression (NERVE COMPRESSION SYNDROMES); PARALYSIS; and ISCHEMIC CONTRACTURE. FASCIOTOMY is often used to decompress increased pressure and eliminate pain associated with compartment syndromes.

Synonym
Compartment Syndromes

Excerpt	Reference
"Compartment syndromes are the result of pathologically elevated tissue pressure and as a rule with a rapid clinical course."	( Biberthaler, P; Braun, KF; Gutwerk, A; Kanz, KG; Karlas, A; Müller, M; Pförringer, D, 2020)
"Majority of compartment syndromes are associated with trauma or surgery."	( Akhtar, S; Joseph, VM; Nagy, MT; Ng, CY, 2020)

Excerpt	Reference
"Delays in diagnosis and treatment of compartment syndromes of the lower extremities result in significant morbidity and mortality."	( Hyde, GL; Peck, D; Powell, DC, 1983)
"Failure to adequately diagnose and treat compartment syndromes of the hand can lead to irreparable functional loss."	( Brinci, L; Cerulli, P; Cervelli, V; D'Asero, G; Palla, L; Petrocelli, M; Tati, E, 2010)
"Early diagnosis and treatment of compartment syndromes is associated with better results; however, many patients have chronic symptoms after treatment, even when the diagnosis is made promptly and fasciotomy is performed early."	( Gorczyca, JT; Pugh, KJ; Ring, D; Roberts, CS, 2011)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	153 (14.73)	23.3326
1990's	195 (18.77)	12.5806
2000's	283 (27.24)	18.1394
2010's	285 (27.43)	28.8240
2020's	123 (11.84)	9.53

Drug	Relationship Strength	Studies	Trials
hydrobromic acid	low	1	0
carbamates	low	1	0
carbon monoxide	low	2	0
aminocaproic acid	low	1	0
lactic acid	medium	6	1
hydrogen carbonate	low	1	0
dalteparin	low	10	0
histamine	low	1	0
methanol	low	1	0
melatonin	low	1	0
phenol	low	1	0
taurine	low	1	0
urea	low	2	0
1-anilino-8-naphthalenesulfonate	low	2	0
n-methyl-3,4-methylenedioxyamphetamine	low	2	0
phenytoin	low	1	0
acetaminophen	low	1	0
acetazolamide	low	3	0
theophylline	medium	7	1
amiodarone	low	1	0
amitriptyline	low	2	0
aspirin	low	3	0
bendroflumethiazide	medium	2	1
bisbenzimidazole	low	1	0
bupivacaine	low	6	0
chlorpromazine	low	2	0
dantrolene	low	4	0
deferoxamine	low	1	0
diazepam	low	2	0
diclofenac	low	1	0
diphenhydramine	low	1	0
valproic acid	low	1	0
fentanyl	low	1	0
fenthion	low	1	0
flunitrazepam	low	1	0
furosemide	low	1	0
gemfibrozil	low	1	0
gentamicin	low	1	0
glyphosate	low	1	0
guaifenesin	low	1	0
halothane	low	1	0
ethidium	low	1	0
ibuprofen	low	1	0
lidocaine	low	3	0
indomethacin	low	1	0
iohexol	low	4	0
ioxaglate	low	1	0
isoflurane	low	2	0
ketorolac	low	1	0
meprobamate	low	1	0
metformin	low	2	0
methadone	low	2	0
methylphenidate	low	1	0
methixene	low	1	0
apnea	low	1	0
nifedipine	low	1	0
nitroglycerin	low	1	0
papaverine	low	1	0
pentobarbital	low	1	0
pentoxifylline	low	1	0
procaine	low	1	0
propofol	low	5	0
risperidone	low	2	0
secobarbital	low	2	0
sumatriptan	low	1	0
temazepam	low	2	0
terbutaline	low	2	0
thalidomide	low	1	0
ticlopidine	low	2	0
tolazoline	low	1	0
trazodone	low	1	0
triazolam	low	1	0
prednisolone	low	4	0
thyroxine	low	4	0
aldosterone	low	2	0
prednisone	low	4	0
triiodothyronine	low	1	0
glutamine	low	1	0
phenylephrine	low	2	0
methylene blue	low	1	0
ampicillin	low	1	0
mannitol	medium	18	1
cytarabine	low	1	0
ethylene	low	1	0
propane	low	1	0
isoprene	low	1	0
trichloroethylene	low	1	0
methylprednisolone	low	6	0
butane	low	1	0
nafcillin	low	1	0
triphenyltetrazolium	low	1	0
calcium gluconate	low	2	0
betamethasone	low	1	0
nandrolone	low	1	0
fluorobenzenes	low	1	0
malondialdehyde	low	4	0
acetylcysteine	low	2	0
erythromycin	low	1	0
deoxycytidine	low	1	0
durapatite	medium	1	1
methylprednisolone hemisuccinate	low	1	0
flupenthixol	low	1	0
sulfur hexafluoride	low	1	0
enbucrilate	low	1	0
neodymium	low	1	0
technetium	low	2	0
gadolinium	low	1	0
yttrium	low	1	0
barium sulfate	low	1	0
calcium sulfate	low	1	0
trolamine salicylate	low	4	0
clodronic acid	low	1	0
triamcinolone	low	1	0
4-methoxyamphetamine	low	2	0
dibutylaminosulfenylcarbofuran	low	1	0
desflurane	low	1	0
idarubicin	low	1	0
propiconazole	low	50	0
atracurium	low	1	0
octenidine	low	1	0
fomesafen	low	1	0
simvastatin	low	3	0
clopidogrel	low	2	0
gemcitabine	low	1	0
technetium tc 99m mertiatide	low	1	0
remifentanil	low	1	0
atorvastatin	low	2	0
adenosine	medium	3	1
cathinone	low	3	0
cisatracurium	low	1	0
iobitridol	low	2	0
iridium radioisotopes	low	1	0
fluorodeoxyglucose f18	low	1	0
sertraline	low	1	0
fibrinogen	low	2	0
cadusafos	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
methotrexate	low	1	0
sulbactam	low	1	0
ropivacaine	low	3	0
glycogen	low	1	0
linezolid	low	1	0
n-formylmethionine leucyl-phenylalanine	low	1	0
sultamicillin	low	1	0
cocaine	low	3	0
clindamycin	low	1	0
melphalan	medium	3	1
sodium bicarbonate	low	1	0
buprenorphine	low	3	0
pyrophosphate	low	1	0
chlorprothixene	low	1	0
D-fructopyranose	low	1	0
thiopental	low	1	0
thiamylal	low	1	0
orlistat	low	2	0
alpha-chymotrypsin	low	1	0
bilirubin	low	2	0
vitamin k semiquinone radical	low	3	0
thromboxane a2	low	1	0
alprostadil	low	1	0
cholecalciferol	low	1	0
amphotericin b	low	1	0
fondaparinux	low	1	0
acitretin	low	1	0
hydromorphone	low	2	0
naloxone	low	1	0
oxycodone	low	2	0
morphine	low	4	0
deamino arginine vasopressin	low	2	0
iloprost	low	2	0
thallium	medium	1	1
ramipril	low	2	0
phosphorus	low	1	0
heroin	low	6	0
technetium tc 99m stannous pyrophosphate	low	1	0
technetium tc 99m pyrophosphate	low	2	0
gadolinium dtpa	low	3	0
vildagliptin	low	1	0
phosphocreatine	low	1	0
amoxicillin-potassium clavulanate combination	low	1	0
mocetinostat	low	6	0
rivaroxaban	low	1	0
indocyanine green	low	2	0
endothelin-1	low	1	0
vendex	low	2	0
technetium tc 99m sestamibi	medium	2	1
ro13-9904	low	1	0
quetiapine fumarate	low	1	0
cardiovascular agents	low	1	0
piperidines	low	1	0
interleukin-8	low	4	0
ascorbic acid	low	2	0
warfarin	low	14	0
bromfenacoum	low	1	0
phenprocoumon	low	1	0
calca protein, human	low	1	0
hirudin	low	3	0
oligomycins	low	1	0
hyaluronoglucosaminidase	low	2	0
ginkgolide b	low	1	0
vitamin b 12	low	1	0
refludan	low	1	0
technetium tc 99m medronate	low	3	0
technetium tc-99m tetrofosmin	medium	1	1
clozapine	low	1	0
oxypurinol	low	1	0
allopurinol	low	3	0
eye	low	7	0
phosphorus radioisotopes	low	1	0

Protein Targets (1,407)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	11	0	0	11
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	4	0	0	4
thioredoxin reductase	32	0	0	32
USP1 protein, partial	27	0	0	27
TDP1 protein	38	0	0	38
vitamin D3 receptor isoform VDRA	20	0	0	20
importin subunit beta-1 isoform 1	8	0	0	8
flap endonuclease 1	13	0	0	13
serine/threonine-protein kinase PLK1	6	0	0	6
snurportin-1	8	0	0	8
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	21	0	0	21
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
geminin	46	0	0	46
DNA polymerase kappa isoform 1	18	0	0	18
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	2	0	2
Transthyretin	0	1	3	8
Fatty acid-binding protein, intestinal	0	4	2	6
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	2	1	3
Cyclin-dependent kinase 2	0	1	2	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	10	0	0	10
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	20	0	0	20
Chain A, Cruzipain	9	0	0	9
regulator of G-protein signaling 4	14	0	0	14
Platelet-activating factor receptor	0	2	0	3
Inositol monophosphatase 1	10	0	0	10
5-hydroxytryptamine receptor 2C	0	12	2	15
5-hydroxytryptamine receptor 2A	0	15	2	17
5-hydroxytryptamine receptor 1A	0	19	4	23
5-hydroxytryptamine receptor 1B	0	14	2	16
5-hydroxytryptamine receptor 1D	0	6	3	9
5-hydroxytryptamine receptor 1F	0	5	2	7
5-hydroxytryptamine receptor 2B	0	10	3	13
5-hydroxytryptamine receptor 6	0	2	2	4
Sodium-dependent serotonin transporter	0	21	3	24
Sodium-dependent serotonin transporter	0	8	1	10
5-hydroxytryptamine receptor 7	0	6	2	8
5-hydroxytryptamine receptor 5A	0	2	2	4
5-hydroxytryptamine receptor 5B	0	2	2	4
5-hydroxytryptamine receptor 3A	0	4	2	6
5-hydroxytryptamine receptor 4	0	2	2	4
5-hydroxytryptamine receptor 3B	0	4	2	6
RAR-related orphan receptor gamma	36	0	0	36
ATAD5 protein, partial	16	0	0	16
GLS protein	19	0	0	19
Microtubule-associated protein tau	17	0	0	17
Smad3	12	0	0	12
aldehyde dehydrogenase 1 family, member A1	32	0	0	32
thyroid stimulating hormone receptor	20	0	0	20
nuclear receptor subfamily 1, group I, member 3	29	0	0	29
progesterone receptor	26	0	0	26
EWS/FLI fusion protein	30	0	0	30
retinoic acid nuclear receptor alpha variant 1	38	0	0	38
retinoid X nuclear receptor alpha	28	0	0	28
estrogen-related nuclear receptor alpha	43	0	0	43
estrogen nuclear receptor alpha	64	0	0	64
peroxisome proliferator activated receptor gamma	26	0	0	26
aryl hydrocarbon receptor	20	0	0	20
chromobox protein homolog 1	32	0	0	32
thyroid hormone receptor beta isoform 2	37	0	0	37
peripheral myelin protein 22	24	0	0	24
cytochrome P450 3A4 isoform 1	17	0	0	17
Gamma-aminobutyric acid receptor subunit pi	17	9	3	29
ATP-binding cassette sub-family C member 3	0	43	0	43
Multidrug resistance-associated protein 4	0	43	0	45
Solute carrier family 22 member 6	0	7	0	7
Carbonic anhydrase 12	0	5	1	10
UDP-glucuronosyltransferase 1A9	0	1	0	5
Bile salt export pump	0	11	0	11
Voltage-dependent calcium channel gamma-2 subunit	19	0	0	19
Bile salt export pump	0	62	0	62
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	16	1	24
Carbonic anhydrase 2	0	16	2	25
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	3	1	5
Cytochrome P450 1A2	0	7	1	10
Prostaglandin G/H synthase 1	0	8	0	9
Carbonic anhydrase 3	0	5	1	9
Cytochrome P450 3A4	0	17	1	20
Cytochrome P450 2D6	0	14	1	18
Cytochrome P450 2C9	0	21	0	24
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	17	9	3	29
Sulfotransferase 1A1	0	0	0	2
Gamma-aminobutyric acid receptor subunit delta	17	9	3	29
Gamma-aminobutyric acid receptor subunit gamma-2	17	9	3	29
UDP-glucuronosyltransferase 1-6	0	2	0	4
Glutamate receptor 2	20	0	0	20
Gamma-aminobutyric acid receptor subunit alpha-5	17	9	3	29
Gamma-aminobutyric acid receptor subunit alpha-3	17	9	3	29
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	3	0	4
Carbonic anhydrase 4	0	9	1	13
Prostaglandin G/H synthase 1	0	9	0	9
Carbonic anhydrase 6	0	7	1	11
Gamma-aminobutyric acid receptor subunit gamma-1	17	9	3	29
Gamma-aminobutyric acid receptor subunit alpha-2	17	9	3	29
Gamma-aminobutyric acid receptor subunit alpha-4	17	9	3	29
Gamma-aminobutyric acid receptor subunit gamma-3	17	9	3	29
Gamma-aminobutyric acid receptor subunit alpha-6	17	9	3	29
Carbonic anhydrase 5A, mitochondrial	0	7	1	12
Prostaglandin G/H synthase 2	0	10	1	12
Carbonic anhydrase 7	0	6	1	10
Nuclear receptor ROR-gamma	11	0	0	11
Cytochrome P450 2J2	0	14	0	15
Gamma-aminobutyric acid receptor subunit alpha-1	17	10	3	30
Gamma-aminobutyric acid receptor subunit beta-3	17	9	3	29
Gamma-aminobutyric acid receptor subunit beta-2	17	9	3	29
Carbonic anhydrase 9	0	8	1	13
GABA theta subunit	17	9	3	29
Canalicular multispecific organic anion transporter 1	0	39	0	39
Carbonic anhydrase 15	0	5	0	7
Carbonic anhydrase 13	0	6	0	9
Gamma-aminobutyric acid receptor subunit epsilon	17	9	3	29
Carbonic anhydrase 14	0	5	1	10
Carbonic anhydrase 5B, mitochondrial	0	7	1	12
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	17	0	0	17
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	16	0	0	16
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	2	0	2
GALC protein	4	0	0	4
GLI family zinc finger 3	34	0	0	34
cytochrome P450 family 3 subfamily A polypeptide 4	30	0	0	30
glucocorticoid receptor [Homo sapiens]	46	0	0	46
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	2	0	2
arylsulfatase A	16	0	0	16
Carbonic anhydrase	0	2	0	2
euchromatic histone-lysine N-methyltransferase 2	44	0	0	44
Bloom syndrome protein isoform 1	18	0	0	18
thyroid hormone receptor beta isoform a	23	0	0	23
nuclear factor erythroid 2-related factor 2 isoform 1	43	0	0	43
survival motor neuron protein isoform d	20	0	0	20
muscleblind-like protein 1 isoform 1	10	0	0	10
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	5	0	5
Cytochrome P450 2A6	0	2	0	2
Androgen receptor	0	9	0	9
Translocator protein	0	3	2	6
Cytochrome P450 2B6	0	5	0	5
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	9	1	12
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	3	1	5
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	8	1	12
Delta-type opioid receptor	0	7	1	10
Cytochrome P450 2C19	0	11	0	13
Delta-type opioid receptor	0	9	3	13
Mu-type opioid receptor	0	12	4	19
Carbonic anhydrase	0	5	0	6
Kappa-type opioid receptor	0	10	1	11
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	6	1	0	7
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	1	0	3
D(2) dopamine receptor	0	10	0	11
Cholinesterase	0	4	0	4
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	8	1	9
Fatty-acid amide hydrolase 1	0	5	0	5
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	4
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase 3	0	3	0	3
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	8	2	10
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	3
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	3	1	6
Carbonic anhydrase 4	0	3	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
acetylcholinesterase	14	0	0	14
dopamine D1 receptor	4	0	0	4
15-lipoxygenase, partial	7	0	0	7
pregnane X receptor	7	0	0	7
phosphopantetheinyl transferase	19	0	0	19
NFKB1 protein, partial	11	0	0	11
Thrombopoietin	6	0	0	6
AR protein	55	0	0	55
farnesoid X nuclear receptor	22	0	0	22
vitamin D (1,25- dihydroxyvitamin D3) receptor	26	0	0	26
D(1A) dopamine receptor	13	0	0	13
heat shock protein beta-1	12	0	0	12
muscarinic acetylcholine receptor M1	17	0	0	17
Histone deacetylase 3	0	5	0	5
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	6	0	6
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	6	0	6
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	4	0	4
Ataxin-2	23	0	0	23
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	4	0	4
ATP-dependent phosphofructokinase	15	0	0	15
Luciferase	19	0	0	19
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	25	0	0	25
eyes absent homolog 2 isoform a	3	0	0	3
histone acetyltransferase KAT2A isoform 1	14	0	0	14
Rap guanine nucleotide exchange factor 3	11	0	0	11
Cellular tumor antigen p53	35	0	0	35
Rap guanine nucleotide exchange factor 4	2	0	0	2
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	3	3
IDH1	20	0	0	20
Histone H2A.x	17	0	0	17
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	11	0	0	11
nuclear receptor ROR-gamma isoform 1	14	0	0	14
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	5	0	5
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	3	0	3
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	7	2	10
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	4	5	11
Adenosine receptor A2b	0	2	1	5
Adenosine receptor A2b	0	2	1	4
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	9	3	15
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	2	1	3
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	3	0	3
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	12
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	3	3	6
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	2
interleukin 8	9	0	0	9
estrogen receptor 2 (ER beta)	20	0	0	20
transcriptional regulator ERG isoform 3	6	0	0	6
ras-related protein Rab-9A	9	0	0	9
lamin isoform A-delta10	40	0	0	40
Polyphenol oxidase 2	0	2	0	3
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	2	2
TAR DNA-binding protein 43	11	0	0	11
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	2	0	4
Thromboxane-A synthase	0	3	0	3
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	3	2	5
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, Ferritin light chain	13	0	0	13
Chain A, Apolipoprotein	0	0	1	1
nonstructural protein 1	9	0	0	9
Plasminogen	0	2	1	3
Proton-coupled amino acid transporter 1	0	3	0	3
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
SMAD family member 2	9	0	0	9
Fumarate hydratase	8	0	0	8
PPM1D protein	8	0	0	8
SMAD family member 3	9	0	0	9
caspase 7, apoptosis-related cysteine protease	9	0	0	9
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
pregnane X nuclear receptor	35	0	0	35
G	21	0	0	21
cytochrome P450 2D6	18	0	0	18
polyprotein	8	0	0	8
peroxisome proliferator-activated receptor delta	22	0	0	22
caspase-3	9	0	0	9
thyroid stimulating hormone receptor	10	0	0	10
v-jun sarcoma virus 17 oncogene homolog (avian)	18	0	0	18
cytochrome P450 2D6 isoform 1	15	0	0	15
cellular tumor antigen p53 isoform a	6	0	0	6
cytochrome P450 2C9 precursor	7	0	0	7
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
huntingtin isoform 2	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	8	0	0	8
lethal factor (plasmid)	7	0	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	0	0	7
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Solute carrier organic anion transporter family member 1A4	0	3	0	5
Voltage-dependent L-type calcium channel subunit alpha-1F	0	12	1	13
5-hydroxytryptamine receptor 4	0	20	0	20
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	28	0	0	28
HLA class I histocompatibility antigen, B alpha chain	21	0	0	21
Thyroid hormone receptor alpha	0	1	0	1
Integrin beta-3	6	1	0	7
Tyrosine-protein kinase Fyn	0	2	0	2
ATP-dependent translocase ABCB1	0	4	0	4
Aldo-keto reductase family 1 member B1	0	15	0	15
Muscarinic acetylcholine receptor M2	0	13	1	15
Muscarinic acetylcholine receptor M4	0	13	1	15
ATP-dependent translocase ABCB1	0	13	1	18
Integrin alpha-IIb	6	1	0	7
Beta-1 adrenergic receptor	0	2	2	4
Muscarinic acetylcholine receptor M5	0	13	0	14
Alpha-2A adrenergic receptor	0	17	2	19
Thyroid hormone receptor alpha	0	3	3	6
Thyroid hormone receptor beta	0	3	3	6
Muscarinic acetylcholine receptor M1	0	13	1	15
Beta-3 adrenergic receptor	0	2	2	4
D(2) dopamine receptor	0	15	0	19
Alpha-1B adrenergic receptor	0	14	2	16
Lethal factor	0	1	0	1
Alpha-2B adrenergic receptor	0	17	1	18
Thyroid hormone receptor beta	0	3	0	3
Muscarinic acetylcholine receptor M3	0	12	1	14
ATP-dependent translocase ABCB1	0	4	0	4
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	11	0	13
D(4) dopamine receptor	0	9	0	12
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	20	3	23
Histamine H2 receptor	0	11	2	13
Endothelin-1 receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	18	0	20
5-hydroxytryptamine receptor 2C	0	21	1	22
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	6	0	6
Mu-type opioid receptor	0	14	5	21
D(3) dopamine receptor	0	15	0	18
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 4 subunit alpha	0	6	0	7
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	12	3	17
Kappa-type opioid receptor	0	13	5	20
5-hydroxytryptamine receptor 2B	0	18	1	19
C-C chemokine receptor type 2	0	4	0	4
Melanocortin receptor 3	0	4	0	4
Alpha-1A adrenergic receptor	0	16	2	18
Histamine H2 receptor	11	1	1	15
5-hydroxytryptamine receptor 6	0	10	0	11
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	19	1	2	22
Sodium channel protein type 7 subunit alpha	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	12	1	13
Sodium-dependent dopamine transporter	0	15	2	17
Potassium voltage-gated channel subfamily H member 2	0	27	0	27
Voltage-dependent L-type calcium channel subunit alpha-1S	0	12	1	13
Voltage-dependent L-type calcium channel subunit alpha-1C	0	13	1	15
Sodium channel protein type 5 subunit alpha	0	8	0	8
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	6	0	6
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	21	0	0	21
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	20	1	21
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	6	0	6
Sodium channel protein type 11 subunit alpha	0	4	0	4
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	4	0	4
Sodium channel protein type 10 subunit alpha	0	4	0	4
cytochrome P450 2C9, partial	21	0	0	21
Chain A, HADH2 protein	17	0	0	17
Chain B, HADH2 protein	17	0	0	17
atrial natriuretic peptide receptor 2 precursor	6	0	0	6
Solute carrier family 22 member 1	0	9	0	12
Albumin	0	0	8	8
High affinity nerve growth factor receptor	0	1	2	3
Muscarinic acetylcholine receptor M1	0	8	0	8
Muscarinic acetylcholine receptor M3	0	7	0	7
Muscarinic acetylcholine receptor M4	0	7	0	7
Muscarinic acetylcholine receptor M5	0	7	0	7
Muscarinic acetylcholine receptor M2	0	7	0	7
Angiotensin-converting enzyme	0	13	0	13
Alpha-2C adrenergic receptor	0	15	1	16
D(1B) dopamine receptor	0	4	0	6
UDP-glucuronosyltransferase 1A4	0	1	0	4
Alpha-1D adrenergic receptor	0	10	0	10
Histamine H1 receptor	0	5	1	6
Histamine H1 receptor	0	17	4	23
UDP-glucuronosyltransferase 1A3	0	0	0	4
5-hydroxytryptamine receptor 7	0	5	0	5
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	12	0	12
Histamine H3 receptor	0	7	2	9
tumor necrosis factor	2	0	0	2
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	0	6
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	0	0	1
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	10	0	0	10
DNA polymerase beta	5	0	0	5
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	2
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	0	0	1
Efflux transporter	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	1	0	2
Class D beta-lactamase	0	1	0	2
60 kDa chaperonin	0	3	0	3
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	3	0	3
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	1	0	2
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	0	0	1
neuropeptide S receptor isoform A	4	0	0	4
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	7	0	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	3
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	3	0	0	3
glucocerebrosidase	7	0	0	7
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	5
Prostaglandin G/H synthase 2	0	3	0	4
Fatty acid-binding protein, liver	0	7	0	7
Myeloperoxidase	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	7	0	7
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	4	1	5
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
Solute carrier organic anion transporter family member 2B1	0	2	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Solute carrier organic anion transporter family member 1B3	0	5	0	9
Solute carrier organic anion transporter family member 1B1	0	7	0	11
Amine oxidase [flavin-containing] A	0	0	1	1
Small conductance calcium-activated potassium channel protein 3	0	2	1	3
glp-1 receptor, partial	15	0	0	15
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
ORF73	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	2	0	0	2
DNA topoisomerase 1	0	1	0	1
DNA topoisomerase 2-alpha	0	1	0	1
DNA topoisomerase 2-beta	0	0	0	1
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	3	5
Potassium channel subfamily K member 9	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	1	0	1
67.9K protein	9	0	0	9
Snq2p	0	0	0	2
Adenylate cyclase type 1	0	3	0	3
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
histone deacetylase 9 isoform 3	3	0	0	3
M-phase phosphoprotein 8	7	0	0	7
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	1	2	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Albumin	0	6	7	14
Major prion protein	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Major prion protein	0	0	1	1
Procathepsin L	0	2	2	4
5-hydroxytryptamine receptor 1A	0	8	4	12
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	2	2	4
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Replicase polyprotein 1ab	0	3	2	5
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	7	0	7
D(3) dopamine receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	8	2	10
D(2) dopamine receptor	0	3	0	3
Proteasome subunit beta type-1	0	1	0	2
Adenylate cyclase type 3	0	3	0	3
Alpha-2C adrenergic receptor	0	8	2	10
Alpha-2A adrenergic receptor	0	8	2	10
Alpha-1D adrenergic receptor	0	10	2	12
Sodium-dependent dopamine transporter	0	11	1	12
D(1B) dopamine receptor	0	5	0	5
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	1	0	2
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	5	0	5
Histamine H1 receptor	0	4	3	8
Pleiotropic ABC efflux transporter of multiple drugs	0	2	0	4
5-hydroxytryptamine receptor 7	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	2	0	3
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	1	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	2	3
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	3
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	0	3
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	3
D	0	3	0	3
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Glutamate receptor ionotropic, NMDA 3A	0	2	0	3
60 kDa chaperonin	0	2	0	2
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	2	2
Vitamin D3 receptor	0	0	1	1
Protein-arginine deiminase type-4	0	2	0	2
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Macrophage metalloelastase	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
Liver carboxylesterase 1	0	1	0	4
P2Y purinoceptor 12	0	1	0	1
Beta-lactamase	0	2	0	2
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase TEM	0	3	0	3
5-hydroxytryptamine receptor 3E	0	2	0	2
Beta-1 adrenergic receptor	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	8	0	0	8
peripheral myelin protein 22 isoform 1	10	0	0	10
cytochrome P450 2C19 precursor	7	0	0	7
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	3	0	3
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Endothelin receptor type B	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Alpha-1A adrenergic receptor	0	5	1	6
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	3	1	4
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 5A	0	2	0	2
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	0	3
5-hydroxytryptamine receptor 3D	0	2	0	2
5-hydroxytryptamine receptor 3C	0	2	0	2
ATPase family AAA domain-containing protein 5	14	0	0	14
Histamine H4 receptor	0	3	3	6
Transporter	0	5	0	5
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	7	0	7
Gamma-aminobutyric acid receptor subunit delta	0	7	0	7
Amyloid-beta precursor protein	1	2	0	3
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	11	7	18
Gamma-aminobutyric acid receptor subunit beta-1	0	7	1	8
Gamma-aminobutyric acid receptor subunit gamma-2	0	10	5	15
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	11	2	13
Gamma-aminobutyric acid receptor subunit alpha-5	0	9	5	14
Gamma-aminobutyric acid receptor subunit alpha-3	0	9	2	11
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	9	3	12
Gamma-aminobutyric acid receptor subunit beta-2	0	8	5	13
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	1	8
Gamma-aminobutyric acid receptor subunit epsilon	0	7	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	6	0	6
Leukotriene B4 receptor 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	9	1	10
Sodium-dependent dopamine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	7	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	0	7	0	7
Leukotriene B4 receptor 2	0	1	0	2
Gamma-aminobutyric acid receptor subunit theta	0	7	0	7
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
endonuclease IV	4	0	0	4
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	3
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
Reverse transcriptase/RNaseH	0	1	1	2
Gamma-aminobutyric acid	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	4
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Translocator protein	0	1	0	1
Translocator protein	0	3	0	3
Cholecystokinin receptor type A	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	5	0	6
Cytochrome c oxidase subunit 2	0	2	0	2
Interleukin-8	0	2	0	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	5
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Solute carrier family 22 member 6	0	3	0	4
Prostaglandin G/H synthase 1	0	3	0	4
Multidrug and toxin extrusion protein 1	0	8	0	8
P2Y purinoceptor 12	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Solute carrier family 22 member 1	0	2	0	4
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
streptokinase A precursor	0	0	2	2
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
Cytochrome P450 1B1	0	3	0	3
Lanosterol 14-alpha demethylase	0	1	0	1
50S ribosomal protein L36 2	0	2	1	3
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Amine oxidase [flavin-containing] A	0	4	0	4
Amine oxidase [flavin-containing] B	0	2	0	2
Kappa-type opioid receptor	0	6	3	10
Mu-type opioid receptor	0	4	2	9
Coagulation factor X	0	3	0	3
thyrotropin-releasing hormone receptor	1	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	4	0	4
Acetylcholinesterase	0	2	0	2
Cholinesterase	0	5	0	5
Vascular endothelial growth factor receptor 1	0	2	0	2
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	6	1	8
Acetylcholinesterase	0	2	0	2
Vascular endothelial growth factor receptor 3	0	2	0	2
Vascular endothelial growth factor receptor 2	0	2	0	2
Acetylcholinesterase	0	1	0	1
Prolyl endopeptidase	0	2	0	2
Carboxylic ester hydrolase	0	3	0	3
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	6	6
Cannabinoid receptor 2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Chain A, Glutamine Binding Protein	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 3	0	1	0	3
Plasma kallikrein	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
5-hydroxytryptamine receptor 1D	0	3	1	6
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Acid-sensing ion channel 3	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	4
Prostaglandin G/H synthase 1	0	2	0	2
Caspase-1	0	2	0	3
Aldo-keto reductase family 1 member C3	0	3	0	3
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
DNA polymerase III, partial	1	0	0	1
Parkin	4	0	0	4
hexokinase-4 isoform 1	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
glucokinase regulatory protein	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
tumor susceptibility gene 101 protein	1	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Prostaglandin E2 receptor EP1 subtype	0	0	1	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	0	1	1
Prostacyclin receptor	0	1	1	2
Prostaglandin D2 receptor	0	0	1	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
Androgen receptor	0	3	1	4
Aldo-keto reductase family 1 member B1	0	3	0	3
Aldo-keto reductase family 1 member C4	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Nitric oxide synthase, inducible	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	4
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Estrogen receptor	0	0	1	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Estrogen receptor beta	0	0	1	1
Renin	0	1	0	1
activating transcription factor 6	8	0	0	8
ClpP	2	0	0	2
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Aromatase	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Metabotropic glutamate receptor 1	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	1	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldehyde oxidase 1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
alpha-galactosidase	2	0	0	2
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	2	3
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Cruzipain	0	1	0	1
Alpha-synuclein	1	0	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	4	2	8
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	3
Mu-type opioid receptor	0	1	0	1
Formyl peptide receptor-related sequence 1	0	0	1	1
fMet-Leu-Phe receptor	0	2	2	4
N-formyl peptide receptor 2	0	0	2	2
FML2_HUMAN	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
Myosin light chain kinase, smooth muscle	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Phosphatidylserine lipase ABHD16A	0	1	0	1
Pancreatic triacylglycerol lipase	0	2	0	3
Lipoprotein lipase	0	1	0	1
Hepatic triacylglycerol lipase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Cannabinoid receptor 2	0	1	0	1
Fatty acid synthase	0	2	0	2
Platelet-activating factor acetylhydrolase	0	1	0	1
Neutral cholesterol ester hydrolase 1	0	1	0	1
Diacylglycerol lipase-alpha	0	1	0	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Diacylglycerol lipase-beta	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Acyl-protein thioesterase 2	0	1	0	1
Diacylglycerol lipase-alpha	0	1	0	1
Endothelial lipase	0	1	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
CREB-binding protein	1	0	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	2
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Tumor necrosis factor	0	1	0	1
Chitotriosidase-1	0	3	1	4
Endochitinase B1	0	3	1	4
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Endolysin	0	0	1	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Protease	0	3	0	3
Alpha-1B adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	0	3	3
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Prothrombin	0	1	1	2
Coagulation factor XII	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Envelope glycoprotein	0	0	1	1
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase SHV-1	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Carboxypeptidase M	0	1	0	1
5-hydroxytryptamine receptor 1B	0	3	1	4
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-2 adrenergic receptor	0	0	1	3
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Adenosine receptor A1	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Trace amine-associated receptor 1	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Cocaine esterase	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Dipeptidyl peptidase 9	0	1	0	1
Dipeptidyl peptidase IV	0	2	0	2
Kynurenine 3-monooxygenase	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Prolyl endopeptidase FAP	0	1	0	1
Prolyl endopeptidase FAP	0	1	0	1
Dipeptidyl peptidase 8	0	2	0	2
Dipeptidyl peptidase 9	0	2	0	2
Dipeptidyl peptidase 2	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (1,039)

Protein Targets (1,407)

Compartment Syndromes

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (1,039)

Drugs Studied (244)

Protein Targets (1,407)