Page last updated: 2024-09-28

Cerebrospinal Fluid Effusion, Subdural

Leakage and accumulation of CEREBROSPINAL FLUID in the subdural space which may be associated with an infectious process; CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; INTRACRANIAL HYPOTENSION; and other conditions.

Synonyms(6)

Synonym
Subdural Cerebrospinal Fluid Leakage
Subdural Effusion
Hygroma, Subdural
Subdural Cerebrospinal Fluid Effusion
Cerebrospinal Fluid Leakage, Subdural
Cerebrospinal Fluid Effusion, Subdural

Research Excerpts

Overview

ExcerptReference
"Postmeningitis subdural effusion is rare in neonates when compared to infants and children."( Bhat, YR; Prakashini, K; Sen, S, 2009)
"Massive subdural effusion is an extremely rare complication of head injury."( Dawar, P; Satyarthee, GD; Sharma, BS, 2013)

Treatment

ExcerptReference
"Thirty-four cases of infantile subdural effusion (ISE) were reviewed in relation to surgical treatment and its prognosis during an average of 4 years of extended follow-up."( Decarlini, E; Deguchi, K; Futamura, A; Nokura, H; Sakai, N; Yamada, H, 1990)

Research

Studies (105)

TimeframeStudies, This Condition (%)All Conditions %
pre-199020 (19.05)23.3326
1990's10 (9.52)12.5806
2000's48 (45.71)18.1394
2010's26 (24.76)28.8240
2020's1 (0.95)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low10
aminocaproic acid0low10
glutaric acid0low10
acetaminophen0low10
acetazolamide0low40
albendazole0low10
aspirin0low10
bupivacaine0low10
caffeine0low20
chloroquine0low10
ciprofloxacin0low10
dibucaine0low10
pentetic acid0medium91
dimercaprol0low10
valproic acid0low10
gentamicin0low10
haloperidol0low10
hydroxyurea0low10
iothalamic acid0low10
iotrolan0low10
prednisolone0low20
methylprednisolone acetate0low10
chloramphenicol0medium41
edetic acid0low10
ampicillin0medium31
mannitol0low10
methylprednisolone0low20
penicillanic acid0low10
ergotamine0low10
durapatite0low10
vancomycin0low20
bisphenol a-glycidyl methacrylate0low10
fluorescein0low20
sabinene0low10
streptomycin0low10
technetium0low80
titanium0low10
gadolinium0low80
transferrin0low20
cefazolin0low10
paclitaxel0low10
amikacin0low10
propiconazole0low70
piperacillin0low10
iopamidol0low10
imipenem, anhydrous0low10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine0low10
imatinib mesylate0low20
tazobactam0low10
technetium tc 99m hydroxymethylene diphosphonate0low10
methotrexate0medium61
levofloxacin0low10
technetium tc 99m pentetate0low20
glycogen0low10
metrizamide0low10
clindamycin0low10
fosfomycin0low10
picibanil0low10
amphotericin b0low10
phenylephrine hydrochloride0low10
iodopyracet0low10
gadolinium dtpa0low80
jaw0low10
interleukin-80low10
phenprocoumon0low10
hyaluronoglucosaminidase0low10
technetium tc 99m medronate0low10
thromboplastin0low10
levoleucovorin0low30

Protein Targets (927)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, Cruzipain4004
regulator of G-protein signaling 44004
Platelet-activating factor receptor0202
Inositol monophosphatase 13003
RAR-related orphan receptor gamma140014
ATAD5 protein, partial7007
GLS protein7007
Microtubule-associated protein tau3003
Smad33003
aldehyde dehydrogenase 1 family, member A19009
thyroid stimulating hormone receptor5005
nuclear receptor subfamily 1, group I, member 3130013
progesterone receptor120012
EWS/FLI fusion protein9009
retinoic acid nuclear receptor alpha variant 1190019
retinoid X nuclear receptor alpha150015
estrogen-related nuclear receptor alpha210021
estrogen nuclear receptor alpha280028
peroxisome proliferator activated receptor gamma120012
aryl hydrocarbon receptor8008
chromobox protein homolog 19009
thyroid hormone receptor beta isoform 2180018
peripheral myelin protein 22120012
cytochrome P450 3A4 isoform 13003
Gamma-aminobutyric acid receptor subunit pi3205
ATP-binding cassette sub-family C member 3017017
Multidrug resistance-associated protein 4017019
Solute carrier family 22 member 60606
Carbonic anhydrase 120417
UDP-glucuronosyltransferase 1A90104
Bile salt export pump0606
Voltage-dependent calcium channel gamma-2 subunit110011
Bile salt export pump024024
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 109114
Carbonic anhydrase 2010216
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20304
Prostaglandin G/H synthase 10202
Carbonic anhydrase 30417
Cytochrome P450 3A4011013
Cytochrome P450 2D60505
Cytochrome P450 2C9 0707
Polyunsaturated fatty acid lipoxygenase ALOX150202
Gamma-aminobutyric acid receptor subunit beta-13205
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta3205
Gamma-aminobutyric acid receptor subunit gamma-23205
UDP-glucuronosyltransferase 1-60103
Glutamate receptor 2110011
Gamma-aminobutyric acid receptor subunit alpha-53205
Gamma-aminobutyric acid receptor subunit alpha-33205
Arachidonate 5-lipoxygenase-activating protein0202
UDP-glucuronosyltransferase 1A1 0103
Carbonic anhydrase 40517
Prostaglandin G/H synthase 10404
Carbonic anhydrase 60416
Gamma-aminobutyric acid receptor subunit gamma-13205
Gamma-aminobutyric acid receptor subunit alpha-23205
Gamma-aminobutyric acid receptor subunit alpha-43205
Gamma-aminobutyric acid receptor subunit gamma-33205
Gamma-aminobutyric acid receptor subunit alpha-63205
Carbonic anhydrase 5A, mitochondrial0518
Prostaglandin G/H synthase 20405
Carbonic anhydrase 70416
Nuclear receptor ROR-gamma4004
Cytochrome P450 2J20303
Gamma-aminobutyric acid receptor subunit alpha-13306
Gamma-aminobutyric acid receptor subunit beta-33205
Gamma-aminobutyric acid receptor subunit beta-23205
Carbonic anhydrase 90519
GABA theta subunit3205
Canalicular multispecific organic anion transporter 1017018
Carbonic anhydrase 150304
Carbonic anhydrase 130405
Gamma-aminobutyric acid receptor subunit epsilon3205
Carbonic anhydrase 140417
Carbonic anhydrase 5B, mitochondrial0417
toxin B0001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase7007
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
thioredoxin reductase110011
GALC protein3003
GLI family zinc finger 3170017
cytochrome P450 family 3 subfamily A polypeptide 4100010
glucocorticoid receptor [Homo sapiens]220022
Carbonic anhydrase 0101
Carbonic anhydrase 0101
arylsulfatase A5005
Carbonic anhydrase0101
euchromatic histone-lysine N-methyltransferase 2180018
Bloom syndrome protein isoform 17007
thyroid hormone receptor beta isoform a5005
nuclear factor erythroid 2-related factor 2 isoform 1160016
geminin200020
survival motor neuron protein isoform d5005
muscleblind-like protein 1 isoform 14004
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Glycogen phosphorylase, muscle form0202
Renin0303
Carbonic anhydrase 20202
Cathepsin B0101
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0405
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80102
Cytochrome P450 2A60202
5-hydroxytryptamine receptor 2A0404
Androgen receptor0404
Translocator protein0101
Cannabinoid receptor 10101
Cytochrome P450 2B60202
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10506
Serum paraoxonase/arylesterase 10303
Dipeptidyl peptidase 40001
Endochitinase0101
Adenosine receptor A2a0406
5-hydroxytryptamine receptor 2B0303
Sodium-dependent serotonin transporter0303
Delta-type opioid receptor0101
Cytochrome P450 2C190303
Delta-type opioid receptor0303
Mu-type opioid receptor0303
Carbonic anhydrase0101
Kappa-type opioid receptor0205
Carbonic anhydrase0101
D(1A) dopamine receptor1203
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0101
D(2) dopamine receptor0303
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Fatty-acid amide hydrolase 10303
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0304
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase 30101
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0101
Sigma intracellular receptor 20202
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10303
Renin0101
Carbonic anhydrase 0101
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130214
Carbonic anhydrase 40202
Acidic mammalian chitinase0101
Carbonic anhydrase 70101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Luciferase5005
glp-1 receptor, partial8008
hypoxia-inducible factor 1 alpha subunit7007
Fumarate hydratase3003
TDP1 protein180018
AR protein230023
caspase 7, apoptosis-related cysteine protease3003
farnesoid X nuclear receptor120012
pregnane X nuclear receptor140014
polyprotein3003
67.9K protein5005
vitamin D (1,25- dihydroxyvitamin D3) receptor100010
caspase-33003
IDH1110011
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
v-jun sarcoma virus 17 oncogene homolog (avian)9009
nuclear receptor subfamily 1, group I, member 26006
Histone H2A.x5005
cellular tumor antigen p53 isoform a2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 17007
nuclear factor erythroid 2-related factor 2 isoform 26006
transcriptional regulator ERG isoform 32002
histone deacetylase 9 isoform 31001
heat shock protein beta-15005
mitogen-activated protein kinase 11001
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
Vif0001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
lamin isoform A-delta10140014
neuropeptide S receptor isoform A1001
Interferon beta6006
Cellular tumor antigen p53150015
Integrin beta-32204
Integrin alpha-IIb2103
Methionine aminopeptidase0101
ATPase family AAA domain-containing protein 5120012
Ataxin-2130013
histone acetyltransferase KAT2A isoform 16006
Aminoglycoside 3'-phosphotransferase 0001
ATP-dependent phosphofructokinase8008
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Chain A, Ferritin light chain4004
Chain A, Apolipoprotein0011
15-lipoxygenase, partial4004
nonstructural protein 15005
D(1A) dopamine receptor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Rap guanine nucleotide exchange factor 31001
Plasminogen0213
Proton-coupled amino acid transporter 10202
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
interleukin 83003
phosphopantetheinyl transferase6006
peroxisome proliferator-activated receptor delta110011
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA6006
Potassium voltage-gated channel subfamily H member 209010
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Chain A, Mutant Al2 6e7p9g0011
Chain A, 2-oxoglutarate Oxygenase9009
Beta-lactamase 0305
acid sphingomyelinase2002
apical membrane antigen 1, AMA12002
Beta-lactamase 0104
Beta-lactamase 0105
Metallo-beta-lactamase type 20004
Metallo-beta-lactamase VIM-11 0003
Metallo-beta-lactamase VIM-20003
Beta-lactamase 0004
Metallo-beta-lactamase0003
Beta-lactamase 0104
DNA polymerase beta4004
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)7007
DNA polymerase kappa isoform 15005
60 kDa heat shock protein, mitochondrial0303
Beta-lactamase OXA-70002
Solute carrier family 15 member 10505
Solute carrier family 15 member 10101
Spike glycoprotein111113
10 kDa heat shock protein, mitochondrial0303
Angiopoietin-1 receptor0011
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase 0003
Solute carrier family 15 member 20202
Thiosulfate sulfurtransferase0303
Metallo-beta-lactamase VIM-130105
Efflux transporter 0001
Beta-lactamase 0105
Beta-lactamase Toho-10002
Beta-lactamase 0001
Class D beta-lactamase0103
60 kDa chaperonin 0303
Metallo-beta-lactamase0003
Solute carrier family 15 member 20202
Beta-lactamase 0105
Beta-lactamase 0002
10 kDa chaperonin 0303
Metallo-b-lactamase 0005
Carbapenem-hydrolyzing beta-lactamase KPC0206
Histamine H3 receptor0004
Beta-lactamase class B VIM-2 0005
Beta-lactamase VIM-1 0105
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
hypothetical protein, conserved1001
cytochrome P450 2D66006
glucocerebrosidase2002
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)5005
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0202
Fatty acid-binding protein, liver0202
Myeloperoxidase0101
Seed linoleate 13S-lipoxygenase-10101
Glutathione hydrolase 1 proenzyme0101
Substance-P receptor0101
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200404
Solute carrier family 22 member 60404
Sigma non-opioid intracellular receptor 10314
Sigma non-opioid intracellular receptor 10213
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Glutamate receptor ionotropic, NMDA 1 0203
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0203
Glutamate receptor ionotropic, NMDA 2C0203
Glutamate receptor ionotropic, NMDA 2D0203
Glutamate receptor ionotropic, NMDA 3B0203
Sodium- and chloride-dependent GABA transporter 20101
Glutamate receptor ionotropic, NMDA 3A0203
SMAD family member 25005
SMAD family member 35005
TSHR protein1001
estrogen receptor 2 (ER beta)8008
thyroid stimulating hormone receptor7007
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Alpha-synuclein1001
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20123
Potassium channel subfamily K member 90101
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
atrial natriuretic peptide receptor 1 precursor1001
nuclear receptor ROR-gamma isoform 13003
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0213
Adenosine receptor A30101
Replicase polyprotein 1ab0213
Amine oxidase [flavin-containing] A0101
Acetylcholinesterase0202
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10114
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0202
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Guanine deaminase0101
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Solute carrier family 22 member 60406
Solute carrier family 22 member 80304
Solute carrier family 22 member 110203
Solute carrier family 22 member 80202
Beta-lactamase 0104
Beta-lactamase 0103
Beta-lactamase 0003
Beta-lactamase 0104
Beta-lactamase 0002
Beta-lactamase 0203
Metallo-beta-lactamase VIM-19 0003
Beta-lactamase 0103
Albumin0123
Beta-lactamase SHV-10103
Beta-lactamase SHV-10205
Beta-lactamase0104
B2 metallo-beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0103
Beta-lactamase 0103
Metallo-beta-lactamase VIM-20003
Beta-lactamase 0002
Solute carrier family 22 member 70102
Beta-lactamase 0103
BlaVIM-1 0003
Beta-lactamase 0003
Beta-lactamase 0001
Beta-lactamase 0103
Solute carrier family 22 member 70101
G3003
activating transcription factor 64004
streptokinase A precursor0022
Dihydroxyacetone phosphate acyltransferase0001
HLA class I histocompatibility antigen, B alpha chain 3003
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Inositol hexakisphosphate kinase 13003
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial3003
PPM1D protein2002
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0112
Replicase polyprotein 1ab0213
glucose-6-phosphate 1-dehydrogenase isoform b0101
flap endonuclease 13003
Transmembrane protease serine 20112
Dihydrofolate reductase 0202
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0022
Amyloid-beta precursor protein0202
Histidine-rich protein PFHRP-II0102
Procathepsin L0112
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50303
Alpha-2A adrenergic receptor0606
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Spike glycoprotein0101
Muscarinic acetylcholine receptor M10303
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0505
Alpha-2C adrenergic receptor0505
DNA ligase 10101
Muscarinic acetylcholine receptor M30202
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Sigma intracellular receptor 20202
Phosphoethanolamine N-methyltransferase0101
Angiotensin-converting enzyme 2 0112
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
cytochrome P450 2C9 precursor2002
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha02111
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
Histamine H2 receptor6007
DNA gyrase subunit B0101
DNA gyrase subunit A0202
Enoyl-[acyl-carrier-protein] reductase [NADH]0002
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0202
Protein-arginine deiminase type-40404
USP1 protein, partial6006
cytochrome P450 2D6 isoform 12002
lysosomal alpha-glucosidase preproprotein2002
potassium voltage-gated channel subfamily H member 2 isoform d6006
Polyunsaturated fatty acid lipoxygenase ALOX15B5005
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
Nuclear receptor subfamily 1 group I member 20022
Eyes absent homolog 20101
Angiotensin-converting enzyme 0101
Beta-lactamase 0102
Beta-lactamase 0101
Adenylate cyclase 0101
5-hydroxytryptamine receptor 40404
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0202
ATP-dependent translocase ABCB10202
Beta-2 adrenergic receptor0202
ATP-dependent translocase ABCB106011
Beta-1 adrenergic receptor0202
D(2) dopamine receptor0417
5-hydroxytryptamine receptor 1A0505
ATP-dependent translocase ABCB10303
D(1A) dopamine receptor0405
Sodium-dependent dopamine transporter0202
Thromboxane-A synthase 0101
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
5-hydroxytryptamine receptor 1B0303
D(3) dopamine receptor0417
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 60303
LMP1 [Human herpesvirus 4]0001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Prothrombin0001
Regulatory protein E20011
DNA topoisomerase 10102
DNA topoisomerase 20001
Caspase-30101
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta0118
Tubulin beta-2B chain0114
Similar to alpha-tubulin isoform 1 0114
Similar to alpha-tubulin isoform 1 0103
Solute carrier organic anion transporter family member 1B30405
acetylcholinesterase6006
thyrotropin-releasing hormone receptor1001
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
Chain A, Protein (aspartate Aminotransferase)0011
Chain A, Aspartate Aminotransferase0011
Solute carrier family 22 member 70001
NFKB1 protein, partial2002
Thrombopoietin1001
Adenylate cyclase type 1 0101
peripheral myelin protein 22 isoform 13003
serine/threonine-protein kinase mTOR isoform 12002
transient receptor potential cation channel subfamily V member 11001
Cocaine esterase0202
Solute carrier family 22 member 1 0101
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Albumin0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
Aldo-keto reductase family 1 member B10303
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M50202
Beta-2 adrenergic receptor0202
Muscarinic acetylcholine receptor M20202
Angiotensin-converting enzyme0101
Integrin alpha-40101
Alpha-1B adrenergic receptor0303
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70305
Beta-1 adrenergic receptor0101
D0202
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0202
D(2) dopamine receptor0202
D(4) dopamine receptor0215
D(1B) dopamine receptor0203
Adenylate cyclase type 30101
Alpha-2C adrenergic receptor0202
UDP-glucuronosyltransferase 1A40102
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0303
Sodium-dependent noradrenaline transporter 0202
5-hydroxytryptamine receptor 3A0101
Histamine H2 receptor0202
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20101
Adenylate cyclase type 40101
5-hydroxytryptamine receptor 1D0101
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 1F0101
Histamine H1 receptor0202
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 7 0101
C-8 sterol isomerase0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Kappa-type opioid receptor0202
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0202
Alpha-1B adrenergic receptor0101
Mu-type opioid receptor0213
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80101
Alpha-1A adrenergic receptor0303
5-hydroxytryptamine receptor 2A0101
5-hydroxytryptamine receptor 70101
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
TAR DNA-binding protein 434004
5-hydroxytryptamine receptor 40101
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Transporter0101
Cholecystokinin receptor type A0101
Protease 0404
Adenylyl cyclase 7 0101
D0101
Sodium channel protein type 2 subunit alpha0101
Transient receptor potential cation channel subfamily V member 40101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Transient receptor potential cation channel subfamily V member 20101
Sodium channel protein type 10 subunit alpha0101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Stromelysin-10022
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
DNA repair protein RAD52 homolog isoform a0001
Tyrosine-protein kinase ABL10224
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0011
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50001
Beta-lactamase 0001
Beta-lactamase0204
Metallo-beta-lactamase type 20001
Beta-lactamase TEM0203
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
Beta-lactamase 0001
Chymotrypsinogen A0101
CAAX prenyl protease 2 isoform 20001
Tubulin beta-4A chain0214
Tubulin beta chain0214
Tubulin alpha-3C chain0214
Tubulin alpha-1B chain0214
Tubulin alpha-4A chain0214
Tubulin beta-4B chain0214
DNA primase0101
Tubulin beta-3 chain0315
Tubulin beta-2A chain0214
Tubulin beta-8 chain0214
Tubulin alpha-3E chain0214
Tubulin alpha-1A chain0214
Multidrug and toxin extrusion protein 10101
Tubulin alpha-1C chain0214
Tubulin beta-6 chain0214
Tubulin beta-2B chain0214
Tubulin beta-1 chain0214
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
importin subunit beta-1 isoform 13003
snurportin-13003
M-phase phosphoprotein 82002
caspase-1 isoform alpha precursor1001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
bromodomain adjacent to zinc finger domain 2B2002
Glucocorticoid receptor04110
Glycine receptor subunit alpha-10404
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
GTP-binding nuclear protein Ran isoform 12002
Genome polyprotein 0101
pregnane X receptor3003
NPC intracellular cholesterol transporter 1 precursor1001
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Receptor tyrosine-protein kinase erbB-20101
Integrin alpha-V 0101
60 kDa chaperonin0101
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
Fibroblast growth factor receptor 10101
Proto-oncogene tyrosine-protein kinase Src0101
Substance-K receptor0202
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
UDP-glucuronosyltransferase 2B10 0101
Delta-type opioid receptor0202
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Beta-tubulin 0101
Nucleotide-binding oligomerization domain-containing protein 20101
Solute carrier organic anion transporter family member 1B10202
endonuclease IV1001
cytochrome P450 2C19 precursor1001
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Beta-lactamase 0102
Beta-lactamase 0001
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20001
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Beta-lactamase 0101
B2 bradykinin receptor0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase OXA-10102
Metallo-beta-lactamase type 20101
Angiotensin-converting enzyme0101
Metallo-beta-lactamase L1 type 30101
Beta-lactamase0101
Beta-lactamase 0101
Beta-lactamase 0101
Histone deacetylase 30202
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Histone deacetylase 10202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
D-alanyl-D-alanine dipeptidase0101
Transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]