Assay ID | Title | Year | Journal | Article |
AID110461 | Ability to activate CBA/CaJ Mice spleen cells to proliferate in vitro by measuring new DNA synthesis in a [3H]thymidine incorporation assay at 0 mM | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID136825 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 100 mg/kg administration | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID202899 | Effect of compound on forest virus infection in mice, Mean survival time through 21 days at 100 mg/kg dose | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| Guanosine analogues. Synthesis of nucleosides of certain 3-substituted 6-aminopyrazolo[3,4-d]pyrimidin-4(5H)-ones as potential immunotherapeutic agents. |
AID136831 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 200 mg/kg administration. | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID110579 | Ability to activate CBA/CaJ Mice spleen cells to proliferate in vitro by measuring new DNA synthesis in a [3H]thymidine incorporation assay at 0.20 mM | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID136357 | Tested against Forest virus infection in mice at dose 100 mg/kg administered intraperitoneally in experiment 2; 11/12(92) | 1990 | Journal of medicinal chemistry, Oct, Volume: 33, Issue:10
| Direct C-glycosylation of guanine analogues: the synthesis and antiviral activity of certain 7- and 9-deazaguanine C-nucleosides. |
AID1285200 | Antiviral activity against Semliki forest virus infected in mouse | 2016 | European journal of medicinal chemistry, May-04, Volume: 113 | Thiazolo[4,5-d]pyrimidines as a privileged scaffold in drug discovery. |
AID134275 | Compound was tested for mean survival time through 21 days after administration of 100 mg/kg, 24 and 18 hr prior to virus inoculation ( forest virus) in mice | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID136827 | Compound was tested for its activity against intraperitoneal administration. | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID136829 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 150 mg/kg oral administration. | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID220074 | In vivo effect on murine NK cell activity in isolated CBA/CaJ mice spleen cells and cytotoxicity measured against YAC-1 cells at a targetor ratio 50:1 | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID134437 | Tested against Forest virus infection in mice at dose 100 mg/kg administered intraperitoneally in experiment 2 | 1990 | Journal of medicinal chemistry, Oct, Volume: 33, Issue:10
| Direct C-glycosylation of guanine analogues: the synthesis and antiviral activity of certain 7- and 9-deazaguanine C-nucleosides. |
AID134280 | Compound was tested for mean survival time through 21 days after oral administration of 150 mg/kg, 24 hr prior to virus inoculation ( forest virus) in mice | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID134438 | Tested against Forest virus infection in mice at dose 100 mg/kg administered intraperitoneally in experiment 3 | 1990 | Journal of medicinal chemistry, Oct, Volume: 33, Issue:10
| Direct C-glycosylation of guanine analogues: the synthesis and antiviral activity of certain 7- and 9-deazaguanine C-nucleosides. |
AID136833 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 50 mg/kg administration | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID134278 | Compound was tested for mean survival time through 21 days after intraperitoneal administration of 150 mg/kg, 24 hr prior to virus inoculation ( forest virus) in mice | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID220072 | In vivo effect on murine NK cell activity in isolated CBA/CaJ mice spleen cells and cytotoxicity measured against YAC-1 cells at a targetor ratio 100:1 | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID202897 | Effect against semliki forest virus infection in mice at an ip dose of 100 mg/kg; 11/12 | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID136832 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 25 mg/kg administration | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID136828 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 150 mg/kg intravenous administration. | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID224755 | Tested against Forest virus infection in mice at dose 100 mg/kg administered intraperitoneally in experiment 1; 9/12(75) | 1990 | Journal of medicinal chemistry, Oct, Volume: 33, Issue:10
| Direct C-glycosylation of guanine analogues: the synthesis and antiviral activity of certain 7- and 9-deazaguanine C-nucleosides. |
AID202900 | Effect of compound on forest virus infection in mice, Mean survival time through 21 days at 200 mg/kg dose | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| Guanosine analogues. Synthesis of nucleosides of certain 3-substituted 6-aminopyrazolo[3,4-d]pyrimidin-4(5H)-ones as potential immunotherapeutic agents. |
AID202898 | Effect against semliki forest virus infection in mice at an ip dose of 200 mg/kg; 11/12 | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID202903 | Effect of compound on forest virus infection in mice at the dose of 200 mg/kg; Tested over 12 mice | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| Guanosine analogues. Synthesis of nucleosides of certain 3-substituted 6-aminopyrazolo[3,4-d]pyrimidin-4(5H)-ones as potential immunotherapeutic agents. |
AID110578 | Ability to activate CBA/CaJ Mice spleen cells to proliferate in vitro by measuring new DNA synthesis in a [3H]thymidine incorporation assay at 0.05 mM | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID134281 | Compound was tested for mean survival time through 21 days after subcutaneous administration of 150 mg/kg, 24 hr prior to virus inoculation ( forest virus) in mice | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID202896 | Effect against semliki forest virus infection in mice at an ip dose of 200 mg/kg | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID134277 | Compound was tested for mean survival time through 21 days after administration of 25 mg/kg, 24 and 18 hr prior to virus inoculation ( forest virus) in mice | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID110577 | Ability to activate CBA/CaJ Mice spleen cells to proliferate in vitro by measuring new DNA synthesis in a [3H]thymidine incorporation assay at 0.01 mM | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID134276 | Compound was tested for mean survival time through 21 days after administration of 200 mg/kg, 24 and 18 hr prior to virus inoculation ( forest virus) in mice | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID136358 | Tested against Forest virus infection in mice at dose 100 mg/kg administered intraperitoneally in experiment 3; 11/12(92) | 1990 | Journal of medicinal chemistry, Oct, Volume: 33, Issue:10
| Direct C-glycosylation of guanine analogues: the synthesis and antiviral activity of certain 7- and 9-deazaguanine C-nucleosides. |
AID192094 | Compound at a dose 100 mg/kg was administered to rat and Percent survivors after coronavirus infection in suckling rats. | 1993 | Journal of medicinal chemistry, Mar-19, Volume: 36, Issue:6
| Modulation of leukocyte genetic expression by novel purine nucleoside analogues. A new approach to antitumor and antiviral agents. |
AID202901 | Effect of compound on forest virus infection in mice at the dose of 100 mg/kg; Tested over 12 mice | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| Guanosine analogues. Synthesis of nucleosides of certain 3-substituted 6-aminopyrazolo[3,4-d]pyrimidin-4(5H)-ones as potential immunotherapeutic agents. |
AID134279 | Compound was tested for mean survival time through 21 days after intravenous administration of 150 mg/kg, 24 hr prior to virus inoculation ( forest virus) in mice | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID118548 | Mean survival time of mice that died; survivors lived through 21 days | 1993 | Journal of medicinal chemistry, Mar-19, Volume: 36, Issue:6
| Modulation of leukocyte genetic expression by novel purine nucleoside analogues. A new approach to antitumor and antiviral agents. |
AID136826 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 100 mg/kg administration. | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID202895 | Effect against semliki forest virus infection in mice at an ip dose of 100 mg/kg | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
AID1372795 | Antiviral activity against Semliki forest virus infected in Swiss Webster mouse assessed as mouse survival at 100 mg/kg, ip measured after 18 to 24 hrs | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
AID136830 | Compound was tested for its activity against forest virus infection in mice, activity was determined by measuring the number of survived mice after 150 mg/kg subcutaneous administration. | 1991 | Journal of medicinal chemistry, Oct, Volume: 34, Issue:10
| Synthesis and antiviral activity of certain guanosine analogues in the thiazolo[4,5-d]pyrimidine ring system. |
AID134436 | Tested against Forest virus infection in mice at dose 100 mg/kg administered intraperitoneally in experiment 1 | 1990 | Journal of medicinal chemistry, Oct, Volume: 33, Issue:10
| Direct C-glycosylation of guanine analogues: the synthesis and antiviral activity of certain 7- and 9-deazaguanine C-nucleosides. |
AID1372800 | Antiviral activity against Semliki forest virus infected in Swiss Webster mouse assessed as mean survival time at 100 mg/kg, ip | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
AID110580 | Ability to activate CBA/CaJ Mice spleen cells to proliferate in vitro by measuring new DNA synthesis in a [3H]thymidine incorporation assay at 0.40 mM | 1990 | Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
| Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |