Page last updated: 2024-09-28

Abdominal Pregnancy

A type of ectopic pregnancy in which the EMBRYO, MAMMALIAN implants in the ABDOMINAL CAVITY instead of in the ENDOMETRIUM of the UTERUS.

Synonyms(2)

Synonym
Abdominal Pregnancy
Pregnancy, Abdominal

Research Excerpts

Overview

ExcerptReference
"Advanced abdominal pregnancy is an ominous occurrence."( Brown, RC; Varner, MW, 1984)
"Abdominal pregnancy is potentially highly morbid and often complicated by postoperative fever."( Bergstrom, R; Mueller, G; Yankowitz, J, 1998)
"Abdominal pregnancy is a rare and life-threatening form of ectopic pregnancy that can present as the extrauterine portion of a heterotopic pregnancy."( Cedars, MI; Scheiber, MD, 1999)
"Abdominal pregnancy is rare, but has high fetal and maternal mortality rates."( Ezenwa, E; Shaw, HA, 2000)
"Diagnosis of abdominal pregnancy is often made late."( Courtois, L; Maillet, R; Riethmuller, D; Schaal, JP, 2003)
"Advanced abdominal pregnancy is a rare, life-threatening condition that presents a number of challenges."( Berkowitz, R; Brown, B; Gaddipati, S; Mitty, H; Nezhat, F; Rahaman, J, 2004)
"Abdominal pregnancy is a rare localization of ectopic pregnancy."( Campillos, JM; Crespo, R; Madani, B; Navarro, R; Tobajas, JJ; Villacampa, A, 2008)
"Abdominal pregnancy is a rare condition that may lead to severe complications."( Bánhidy, F; Börzsönyi, B; Csatlós, É; Demendi, C; Joó, JG; Langmár, Z, 2011)
"Abdominal pregnancy is a rare condition that is potentially life-threatening for the mother."( Baba, T; Endo, T; Honnma, H; Ikeda, H; Ikeda, K; Morishita, M; Saito, T; Shimizu, A; Takenami, N, 2012)
"Abdominal pregnancy is a rare condition that accounts for only 1% of all ectopic pregnancies but results in high maternal morbidity and mortality."( Kato, K; Kobayashi, H; Oishi, H; Tsunematsu, R; Uchida, S; Yahata, H; Yasutake, N, 2013)

Treatment

ExcerptReference
"We present a case of abdominal pregnancy with massive peritoneal bleeding successfully treated using systemic methotrexate (MTX)."( Kato, K; Kobayashi, H; Oishi, H; Tsunematsu, R; Uchida, S; Yahata, H; Yasutake, N, 2013)
"BACKGROUND Laparoscopic treatments of abdominal pregnancy have been reported; however, resection of an implanted gestational sac could lead to massive bleeding and treatment failure."( Aihara, Y; Ako, S; Fukuda, T; Hishikawa, K; Inoue, H; Kohata, Y; Kubo, Y; Kusaka, T; Monma, M; Ochiai, N; Watanabe, R, 2016)

Research

Studies (87)

TimeframeStudies, This Condition (%)All Conditions %
pre-199046 (52.87)23.3326
1990's5 (5.75)12.5806
2000's16 (18.39)18.1394
2010's16 (18.39)28.8240
2020's4 (4.60)9.53
DrugIndicatedRelationship StrengthStudiesTrials
metyrapone0low10
potassium chloride0low30
estriol0low80
aldosterone0low10
estrone0low20
norethindrone0low10
ampicillin0low10
levonorgestrel0low10
technetium0low20
cefotetan0low10
methotrexate0low330
angiotensin ii0low10
oxytocin0low60
dactinomycin0low10
enclomiphene0low20
17-ketosteroids0low20
phenylephrine hydrochloride0low10
morphine0low10
lysophosphatidylcholines0low10
pregnanediol0low30
pituitrin0low10
enerbol0low120
clove0low20
menotropins0low20
eye0low10

Protein Targets (410)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
AR protein9009
glucocorticoid receptor [Homo sapiens]7007
thyroid hormone receptor beta isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 23003
geminin100010
Sex hormone-binding globulin0044
Corticosteroid-binding globulin0303
Mineralocorticoid receptor 0123
Androgen receptor0606
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A10203
Guanine nucleotide-binding protein G1001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, Mutant Al2 6e7p9g0011
Chain A, Beta-lactamase4004
Chain A, 2-oxoglutarate Oxygenase3003
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Cruzipain3003
Beta-lactamase 0001
acid sphingomyelinase2002
GLS protein1001
GLI family zinc finger 38008
apical membrane antigen 1, AMA11001
retinoic acid nuclear receptor alpha variant 16006
farnesoid X nuclear receptor5005
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
euchromatic histone-lysine N-methyltransferase 27007
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
chromobox protein homolog 16006
thyroid hormone receptor beta isoform 26006
DNA polymerase beta4004
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)6006
DNA polymerase kappa isoform 14004
Carbonic anhydrase 10202
Carbonic anhydrase 20213
60 kDa heat shock protein, mitochondrial0101
Beta-lactamase OXA-70001
Solute carrier family 15 member 10202
Solute carrier family 15 member 10101
Spike glycoprotein4004
10 kDa heat shock protein, mitochondrial0101
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Thiosulfate sulfurtransferase0101
Metallo-beta-lactamase VIM-130001
Efflux transporter 0001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0001
60 kDa chaperonin 0101
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
10 kDa chaperonin 0101
Metallo-b-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase VIM-1 0001
ATP-dependent phosphofructokinase2002
glucocerebrosidase1001
histone acetyltransferase KAT2A isoform 12002
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0224
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0202
Chain A, JmjC domain-containing histone demethylation protein 3A2002
thioredoxin glutathione reductase2002
bromodomain adjacent to zinc finger domain 2B2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
potassium voltage-gated channel subfamily H member 2 isoform d2002
lethal(3)malignant brain tumor-like protein 1 isoform I1001
DNA dC->dU-editing enzyme APOBEC-3G isoform 10101
DNA dC->dU-editing enzyme APOBEC-3A isoform a0101
ATP-binding cassette sub-family C member 30303
Multidrug resistance-associated protein 40304
Bile salt export pump0808
TAR DNA-binding protein 433003
Canalicular multispecific organic anion transporter 10303
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, Ferritin light chain2002
interleukin 81001
15-lipoxygenase, partial2002
hypoxia-inducible factor 1 alpha subunit2002
RAR-related orphan receptor gamma5005
USP1 protein, partial3003
TDP1 protein8008
Microtubule-associated protein tau3003
caspase 7, apoptosis-related cysteine protease1001
aldehyde dehydrogenase 1 family, member A13003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
estrogen receptor 2 (ER beta)6006
nuclear receptor subfamily 1, group I, member 35005
progesterone receptor6006
cytochrome P450 family 3 subfamily A polypeptide 45005
retinoid X nuclear receptor alpha5005
estrogen-related nuclear receptor alpha6006
pregnane X nuclear receptor4004
estrogen nuclear receptor alpha8008
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma4004
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
caspase-31001
RAD510101
aryl hydrocarbon receptor1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
activating transcription factor 62002
v-jun sarcoma virus 17 oncogene homolog (avian)2002
Histone H2A.x4004
Caspase-71001
Bloom syndrome protein isoform 14004
vitamin D3 receptor isoform VDRA3003
caspase-31001
huntingtin isoform 21001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
nuclear factor erythroid 2-related factor 2 isoform 15005
nuclear receptor ROR-gamma isoform 13003
peripheral myelin protein 225005
survival motor neuron protein isoform d2002
cytochrome P450 3A4 isoform 13003
caspase-1 isoform alpha precursor2002
Gamma-aminobutyric acid receptor subunit pi3003
Voltage-dependent calcium channel gamma-2 subunit5005
Interferon beta5005
Cellular tumor antigen p535005
ATP-dependent translocase ABCB10102
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Glutamate receptor 25005
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Nuclear receptor ROR-gamma1001
Caspase-72002
Gamma-aminobutyric acid receptor subunit alpha-13003
Growth factor receptor-bound protein 20101
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0101
GABA theta subunit3003
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
ATPase family AAA domain-containing protein 54004
Ataxin-24004
Gamma-aminobutyric acid receptor subunit epsilon3003
glp-1 receptor, partial2002
chaperonin-containing TCP-1 beta subunit homolog1001
phosphopantetheinyl transferase2002
Smad31001
IDH13003
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0001
5-hydroxytryptamine receptor 40202
Epidermal growth factor receptor0101
Estrogen receptor08110
Receptor tyrosine-protein kinase erbB-20101
Tyrosine-protein kinase Fyn0101
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0213
Adenosine receptor A30202
Cytochrome P450 2D60202
Muscarinic acetylcholine receptor M10202
Beta-3 adrenergic receptor0202
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
Substance-K receptor0202
Prostaglandin G/H synthase 10101
Sodium-dependent noradrenaline transporter 0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Sodium-dependent serotonin transporter0808
C-8 sterol isomerase0101
D(3) dopamine receptor0202
Alpha-synuclein1203
5-hydroxytryptamine receptor 2B0404
Alpha-1A adrenergic receptor0202
5-hydroxytryptamine receptor 60202
Sodium-dependent dopamine transporter 0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sigma non-opioid intracellular receptor 10303
Glucocorticoid receptor0404
Glycine receptor subunit alpha-10404
Polyunsaturated fatty acid lipoxygenase ALOX150202
UDP-glucuronosyltransferase 2B70001
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Lanosterol 14-alpha demethylase0011
Olfactory receptor 51E20011
UDP-glucuronosyltransferase 1A100001
endonuclease IV1001
ATAD5 protein, partial4004
NFKB1 protein, partial1001
GALC protein3003
nonstructural protein 11001
G4004
arylsulfatase A1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
hexokinase-4 isoform 11001
peripheral myelin protein 22 isoform 11001
glucokinase regulatory protein1001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
lamin isoform A-delta106006
Rap guanine nucleotide exchange factor 31001
HLA class I histocompatibility antigen, B alpha chain 4004
Steryl-sulfatase0101
Aromatase0202
17-beta-hydroxysteroid dehydrogenase type 10203
Mu-type opioid receptor0328
Mu-type opioid receptor0213
Inositol monophosphatase 11001
Cytochrome P450 1B10101
Inositol hexakisphosphate kinase 14004
Estrogen receptor beta0113
Ghrelin O-acyltransferase0101
Broad substrate specificity ATP-binding cassette transporter ABCG20102
cytochrome P450 2C9, partial4004
SMAD family member 22002
SMAD family member 32002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
thyroid stimulating hormone receptor3003
transcriptional regulator ERG isoform 32002
Progesterone receptor0235
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor1001
thioredoxin reductase3003
ClpP1001
EWS/FLI fusion protein1001
67.9K protein1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
cellular tumor antigen p53 isoform a1001
polyunsaturated fatty acid lipoxygenase ALOX121001
importin subunit beta-1 isoform 11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
flap endonuclease 11001
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
M-phase phosphoprotein 81001
muscleblind-like protein 1 isoform 11001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Integrin beta-31001
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0202
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0315
Kappa-type opioid receptor0315
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Cytochrome P450 1A20101
Cytochrome P450 3A40213
Cytochrome P450 2C80101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Cytochrome P450 2C190101
cytochrome P450 2D62002
neuropeptide S receptor isoform A1001
Opioid receptor, delta 1b 0101
Solute carrier family 22 member 1 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
ATP-dependent translocase ABCB10101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M20101
Translocator protein0011
ATP-dependent translocase ABCB10101
Proteinase-activated receptor 10112
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0102
Kappa-type opioid receptor0214
Mu-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0214
Kappa-type opioid receptor0202
Kappa-type opioid receptor0214
Mu-type opioid receptor0215
Nociceptin receptor0101
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor0101
Potassium voltage-gated channel subfamily H member 20202
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Estrogen receptor0011
Estrogen receptor beta0011
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0213
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Carbonic anhydrase 40101
Carbonic anhydrase 5A, mitochondrial0101
Taste receptor type 2 member 310011
Taste receptor type 2 member 600011
Carbonic anhydrase 90101
Sodium/potassium/calcium exchanger 40112
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 90011
Taste receptor type 2 member 40011
Sodium/potassium/calcium exchanger 20112
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]