Compounds > enterocin a
Page last updated: 2024-10-15

enterocin a

Description

enterocin A: isolated from Enterococcus faecium; amino acid sequence in first source; do not confuse with enterocin [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID139587481
MeSH IDM0280312

Synonyms (1)

Synonym
enterocin a

Research Excerpts

Overview

Enterocin A (EntA) is a low molecular weight, heat-stable, chromosomally encoded class IIa bacteriocin produced by several strains of Enterococcus faecium. It has selective antimicrobial activity against Listeria strains.

ExcerptReference
"Enterocin A is a classic IIa bacteriocin isolated firstly from Enterococcus faecium CTC492 with selective antimicrobial activity against Listeria strains. "( Biotechnical paving of recombinant enterocin A as the candidate of anti-Listeria agent.
Hu, X; Huang, J; Mao, R; Teng, D; Wang, J; Wang, X; Xi, D; Zhang, Y, 2014)
"Enterocin A (EntA) is a low molecular weight, heat-stable, chromosomally encoded class IIa bacteriocin produced by several strains of Enterococcus faecium. "( Isolation and characterization of a nitrosoguanidine-induced Enterococcus faecium MTCC 5153 mutant defective in enterocin biosynthesis.
Halami, PM, 2010)
"Enterocin A is an example of a class IIa bacteriocin with potent anti-listerial activity. "( Controlling Listeria monocytogenes in Cottage cheese through heterologous production of enterocin A by Lactococcus lactis.
Cotter, PD; Hill, C; Liu, L; O'Conner, P; Ross, RP, 2008)
"Enterocin A is a small, heat-stable, antilisterial bacteriocin produced by Enterococcus faecium DPC1146. "( Characterization and heterologous expression of the genes encoding enterocin a production, immunity, and regulation in Enterococcus faecium DPC1146.
Hill, C; O'Keeffe, T; Ross, RP, 1999)

Actions

ExcerptReference
"Enterocin A, because of its remarkable antilisterial activity."( Enhancement of the antibacterial activity of an E. faecalis strain by the heterologous expression of enterocin A.
Quirasco, M; Serrano-Maldonado, CE, 2018)

Toxicity

ExcerptReference
" Therefore, it may be useful as a safe natural agent in preservation of foods or as a new probiotic strain in food and feed."( Safety characterisation and inhibition of fungi and bacteria by a novel multiple enterocin-producing Enterococcus lactis 4CP3 strain.
Ben Braïek, O; Cremonesi, P; Ghrairi, T; Hani, K; Morandi, S; Smaoui, S, 2018)

Compound-Compound Interactions

ExcerptReference
" In the present study, the circular bacteriocin enterocin AS-48, applied singly or in combination with phenolic compounds (carvacrol, eugenol, geraniol, and citral) or with 2-nitro-1-propanol (2NPOH), was investigated in the control of a cocktail made from 1 methicillin-sensitive and 1 MRSA strains inoculated on commercial oat and soya drinks."( Inactivation of Staphylococcus aureus in Oat and Soya Drinks by Enterocin AS-48 in Combination with Other Antimicrobials.
Aguayo, MC; Burgos, MJ; Gálvez, A; López, RL; Pulido, RP, 2015)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (50)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (6.00)18.2507
2000's21 (42.00)29.6817
2010's22 (44.00)24.3611
2020's4 (8.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (1.89%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other52 (98.11%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetoin
[no description available]		2.1310methyl ketone;
secondary alpha-hydroxy ketone		metabolite
lactic acid
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.		7.44202-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
ciprofloxacin
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.. ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.		2.1310aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
nalidixic acid
[no description available]		2.13101,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor
ampicillin
Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.. ampicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.		2.1310beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
nitrosoguanidines
Nitrosoguanidines: Nitrosylated derivatives of guanidine. They are used as MUTAGENS in MOLECULAR BIOLOGY research.		2.0510
2-nitropropanol
2-nitropropanol: has antimicrobial activity; a cross-linking reagent		2.1110C-nitro compound
salivaricin a
salivaricin A: from Streptococcus salivarius; MW 2315 kDa; 22-residue peptide containing one lanthionine & two beta-methyllanthionine residues; amino acid sequence given in first source		2.0510
cellulose
DEAE-Cellulose: Cellulose derivative used in chromatography, as ion-exchange material, and for various industrial applications.		7.0210glycoside
pediocin pa-1
pediocin PA-1: from Pediococcus acidilactici PAC-1.0; a 4.6 kDa peptide with 44 amino acids; exhibits antibacterial activity against several gram-positive bacterial strains; amino acid sequence given in first source		7.4120
divercin v41
divercin V41: isolated from Carnobacterium divergens; amino acid sequence in first source; GenBank AJ224003		210
pediocin a
pediocin A: from Pediococcus pentosaceus FBB61		2.0210
lacticin 481
lacticin 481: amino acid sequence given in first source; a lantibiotic; GenBank X71410 (L. lactis)		2.0110
enterocin
enterocin: antibiotic isolated from Streptomyces candidus var. enterostaticus WS-8096 & Streptomyces viridochromogenes M-127; molecular formula: C22-H20-010; structure		2.520
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Stomach
[description not available]		02.3110
Stomach Neoplasms
Tumors or cancer of the STOMACH.		02.3110
Food Poisoning
[description not available]		02.1710
Bacterial Infections, Gram-Positive
[description not available]		02.1510
Gram-Positive Bacterial Infections
Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.		02.1510
Poultry Diseases
Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.		03.411