Abscess, Psoas

Abscess of the PSOAS MUSCLES resulting usually from disease of the lumbar vertebrae, with the pus descending into the muscle sheath. The infection is most commonly tuberculous or staphylococcal.

Synonym
Iliopsoas Abscess
Psoas Abscess
Pyogenic Iliopsoas Abscess
Abscess, Psoas

Excerpt	Reference
"Psoas abscess is a serious health problem which presents with non-specific symptoms and signs."	( Chiu, NT; Jou, IM; Wu, CC; Yao, WJ, 1997)
"The psoas abscess is a rare complication in obstetric and gynaecology."	( Anaf, V; Kirkpatrick, C; Saylam, K, 2002)
"Psoas abscess is an uncommon pathology whose presenting features are usually unspecific."	( Capitán Manjón, C; Cruceyra Betriu, G; Leiva Galvis, O; Piedra Lara, JD; Rosino Sánchez, A; Tejido Sánchez, A; Villacampa Aubá, F, 2002)
"Psoas abscess is a rare disease in developed countries."	( Audia, S; Buisson, M; Chavanet, P; Couaillier, JF; Duong, M; Grappin, M; Lorcerie, B; Martha, B; Piroth, L; Portier, H, 2006)
"Psoas abscess is a rare clinical entity that occurs chiefly after intra-abdominal or retroperitoneal infection."	( Bagot, M; Bularca, S; Roujeau, JC; Routier, E; Sbidian, E, 2010)
"Iliopsoas abscess is a rare complication in hemodialysis patients that is mainly due to adjacent catheterization, local acupuncture, discitis, and bacteremia."	( Fang, YW; Hsiao, PJ; Leu, JG; Tsai, MH, 2015)
"Iliopsoas abscess is a collection of pus in the iliopsoas muscle compartment."	( Low, SG; Vasanwala, FF; Xu, BY, 2019)

Excerpt	Reference
"Failure to recognize and treat psoas abscess results in considerable morbidity."	( Fazio, VW; Lavery, IC; Oakley, JR; Procaccino, JA, 1991)
"We describe a primary iliopsoas abscess by Streptococcus sanguis affecting an 81-year-old man cured by antibiotic therapy and aspiration procedure."	( de Souza Lima, G; dos Santos, VM; Fachinelli, LR; Farage, L; Machado de Carvalho, MR; Nogueira de Andrade, IG, 2015)
"A high index of suspicion of iliopsoas abscess should be maintained among haemodialysis patients presenting with intradialytic pelvic and hip pain and treated with optimal antibiotics therapy with appropriate surgical intervention."	( Alif Adlan, MT; Mohd Ramadhan, MD; Wan Mohd Rasis, WA, 2016)
"We describe a patient with iliopsoas abscess who presented to the Emergency Department at X Hospital on three separate occasions with non-specific symptoms of thigh pain and fever before finally being admitted for treatment."	( Low, SG; Vasanwala, FF; Xu, BY, 2019)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1 (0.68)	23.3326
1990's	23 (15.75)	12.5806
2000's	61 (41.78)	18.1394
2010's	54 (36.99)	28.8240
2020's	7 (4.79)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
methanol	low	1	0
pyrazinamide	medium	4	1
albendazole	low	1	0
azathioprine	low	1	0
bupivacaine	low	1	0
cefuroxime	low	2	0
ciprofloxacin	low	9	0
diclofenac	low	1	0
etodolac	low	1	0
fentanyl	low	1	0
fluconazole	low	2	0
fluorouracil	low	1	0
gabexate	low	1	0
gentamicin	low	10	0
guaifenesin	low	1	0
lidocaine	low	1	0
ifosfamide	low	1	0
ioversol	low	1	0
isoniazid	medium	5	1
metronidazole	low	4	0
nalidixic acid	low	1	0
sulfamethoxazole	low	1	0
trimethoprim	low	1	0
prednisolone	low	5	0
penicillin g	low	1	0
chloramphenicol	low	1	0
methicillin	low	3	0
cloxacillin	low	6	0
oxacillin	low	2	0
ampicillin	low	4	0
mannitol	low	1	0
methylprednisolone	low	1	0
penicillanic acid	low	1	0
methamphetamine	low	1	0
ethambutol	low	1	0
vancomycin	low	15	0
dicloxacillin	low	1	0
streptomycin	low	4	0
floxacillin	low	2	0
enbucrilate	low	1	0
technetium	low	2	0
gadolinium	low	1	0
barium sulfate	low	1	0
trolamine salicylate	low	3	0
cefazolin	low	4	0
amoxicillin	low	4	0
gallium citrate	low	2	0
tobramycin	low	1	0
amikacin	low	3	0
epirubicin	low	1	0
piperacillin	low	1	0
itraconazole	low	4	0
cephalosporin c	low	4	0
fluorodeoxyglucose f18	low	2	0
imipenem, anhydrous	low	5	0
tazobactam	low	1	0
sulbactam	low	2	0
beta-lactams	low	1	0
levofloxacin	low	2	0
ertapenem	low	1	0
naproxen	low	1	0
temocillin	low	1	0
deoxycholic acid	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	3	0
carboplatin	low	1	0
epiglucan	low	1	0
meropenem	low	2	0
cefoxitin	low	1	0
linezolid	low	4	0
sultamicillin	low	1	0
clindamycin	low	2	0
dactinomycin	low	1	0
mercaptopurine	low	1	0
fusidic acid	low	1	0
isepamicin	low	1	0
amphotericin b	low	6	0
barium	low	1	0
gallium	low	2	0
pregabalin	low	1	0
cefotaxime	low	2	0
cilastatin	low	1	0
gadolinium dtpa	low	2	0
technetium tc 99m diphosphonate	low	1	0
technetium tc 99m exametazime	low	1	0
amphotericin b, deoxycholate drug combination	low	1	0
ro13-9904	low	9	0
piperacillin, tazobactam drug combination	low	1	0
mannans	low	1	0
daptomycin	low	2	0
cyclosporine	low	1	0
technetium tc 99m medronate	low	1	0
technetium tc 99m dimercaptosuccinic acid	low	1	0
levoleucovorin	low	1	0
rifampin	medium	11	1
allopurinol	low	1	0

Protein Targets (743)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Beta-lactamase	7	0	0	7
Luciferase	6	0	0	6
glp-1 receptor, partial	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
RAR-related orphan receptor gamma	15	0	0	15
ATAD5 protein, partial	6	0	0	6
Fumarate hydratase	5	0	0	5
TDP1 protein	19	0	0	19
GLI family zinc finger 3	19	0	0	19
AR protein	24	0	0	24
caspase 7, apoptosis-related cysteine protease	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	9	0	0	9
progesterone receptor	10	0	0	10
glucocorticoid receptor [Homo sapiens]	18	0	0	18
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
retinoid X nuclear receptor alpha	15	0	0	15
estrogen-related nuclear receptor alpha	15	0	0	15
farnesoid X nuclear receptor	13	0	0	13
pregnane X nuclear receptor	15	0	0	15
estrogen nuclear receptor alpha	30	0	0	30
polyprotein	5	0	0	5
67.9K protein	4	0	0	4
peroxisome proliferator activated receptor gamma	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	12	0	0	12
caspase-3	2	0	0	2
IDH1	7	0	0	7
euchromatic histone-lysine N-methyltransferase 2	20	0	0	20
aryl hydrocarbon receptor	9	0	0	9
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
Histone H2A.x	6	0	0	6
cellular tumor antigen p53 isoform a	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
chromobox protein homolog 1	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
transcriptional regulator ERG isoform 3	5	0	0	5
thyroid hormone receptor beta isoform 2	12	0	0	12
histone deacetylase 9 isoform 3	1	0	0	1
heat shock protein beta-1	4	0	0	4
mitogen-activated protein kinase 1	3	0	0	3
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
geminin	21	0	0	21
Vif	0	0	0	1
peripheral myelin protein 22	7	0	0	7
survival motor neuron protein isoform d	6	0	0	6
muscleblind-like protein 1 isoform 1	6	0	0	6
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
lamin isoform A-delta10	16	0	0	16
neuropeptide S receptor isoform A	2	0	0	2
ATP-binding cassette sub-family C member 3	0	30	0	30
Multidrug resistance-associated protein 4	0	30	0	31
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Bile salt export pump	0	39	0	39
Interferon beta	15	0	0	15
Cellular tumor antigen p53	16	0	0	16
Integrin beta-3	2	0	0	2
Integrin alpha-IIb	2	0	0	2
Methionine aminopeptidase	0	1	0	1
Glutamate receptor 2	8	0	0	8
Fatty-acid amide hydrolase 1	0	2	0	2
Inositol monophosphatase 1	1	0	0	1
Canalicular multispecific organic anion transporter 1	0	29	0	29
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	7	0	0	7
interleukin 8	10	0	0	10
thyroid stimulating hormone receptor	9	0	0	9
estrogen receptor 2 (ER beta)	9	0	0	9
Bloom syndrome protein isoform 1	6	0	0	6
ras-related protein Rab-9A	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	17	0	0	17
Polyphenol oxidase 2	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	0	1	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	2	2
TAR DNA-binding protein 43	6	0	0	6
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	7
histone acetyltransferase KAT2A isoform 1	6	0	0	6
Aminoglycoside 3'-phosphotransferase	0	0	0	1
ATP-dependent phosphofructokinase	6	0	0	6
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	6	0	0	6
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	6
Beta-lactamase	0	0	0	7
Beta-lactamase	0	2	0	8
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	5	0	0	5
DNA polymerase kappa isoform 1	3	0	0	3
Bile salt export pump	0	12	0	12
Beta-lactamase SHV-1	0	1	0	5
Beta-lactamase SHV-1	0	3	0	9
Cytochrome P450 2C9	0	9	0	11
Beta-lactamase	0	2	0	9
Kappa-type opioid receptor	0	2	0	7
Solute carrier family 15 member 1	0	12	0	12
Solute carrier family 15 member 1	0	2	0	2
Cytochrome P450 2J2	0	5	0	5
B2 metallo-beta-lactamase	0	0	0	5
Solute carrier family 15 member 2	0	7	0	7
Beta-lactamase	0	1	0	5
Beta-lactamase	0	0	0	4
Solute carrier family 15 member 2	0	7	0	7
Beta-lactamase	0	1	0	5
Beta-lactamase	0	0	0	6
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, Cruzipain	5	0	0	5
phosphopantetheinyl transferase	7	0	0	7
GLS protein	5	0	0	5
peroxisome proliferator-activated receptor delta	9	0	0	9
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	7	0	0	7
Cytochrome P450 1A2	0	4	0	5
Cytochrome P450 3A4	0	7	0	8
Cytochrome P450 2D6	0	3	0	4
Cytochrome P450 2C19	0	4	0	5
Nuclear receptor ROR-gamma	3	0	0	3
Potassium voltage-gated channel subfamily H member 2	0	8	0	9
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Beta-lactamase	0	4	0	7
acid sphingomyelinase	1	0	0	1
Beta-lactamase	0	2	0	6
Beta-lactamase	0	1	0	7
Metallo-beta-lactamase type 2	0	0	1	8
Metallo-beta-lactamase VIM-11	0	0	0	6
Metallo-beta-lactamase VIM-2	0	0	0	6
Beta-lactamase	0	1	0	8
Metallo-beta-lactamase	0	0	0	6
Beta-lactamase	0	2	0	6
DNA polymerase beta	2	0	0	2
Carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	5
Spike glycoprotein	6	0	0	6
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	5
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	0	0	6
Efflux transporter	0	1	0	3
Beta-lactamase	0	1	0	7
Beta-lactamase Toho-1	0	0	0	3
Beta-lactamase	0	1	0	3
Class D beta-lactamase	0	2	0	6
60 kDa chaperonin	0	3	0	3
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	8
Beta-lactamase	0	0	1	5
10 kDa chaperonin	0	3	0	3
Metallo-b-lactamase	0	0	0	11
Carbapenem-hydrolyzing beta-lactamase KPC	0	3	0	10
Beta-lactamase class B VIM-2	0	0	1	12
Beta-lactamase VIM-1	0	0	0	6
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, Ferritin light chain	3	0	0	3
acetylcholinesterase	7	0	0	7
thioredoxin reductase	8	0	0	8
SMAD family member 2	4	0	0	4
SMAD family member 3	4	0	0	4
Microtubule-associated protein tau	6	0	0	6
thioredoxin glutathione reductase	5	0	0	5
EWS/FLI fusion protein	15	0	0	15
G	10	0	0	10
P53	1	0	0	1
arylsulfatase A	5	0	0	5
thyroid stimulating hormone receptor	3	0	0	3
activating transcription factor 6	8	0	0	8
peripheral myelin protein 22 isoform 1	3	0	0	3
hemoglobin subunit beta	3	0	0	3
cytochrome P450 3A4 isoform 1	7	0	0	7
M-phase phosphoprotein 8	1	0	0	1
muscarinic acetylcholine receptor M1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	7	3	0	10
HLA class I histocompatibility antigen, B alpha chain	10	0	0	10
Gamma-aminobutyric acid receptor subunit beta-1	7	3	0	10
Gamma-aminobutyric acid receptor subunit delta	7	3	0	10
Gamma-aminobutyric acid receptor subunit gamma-2	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-5	7	3	0	10
Gamma-aminobutyric acid receptor subunit alpha-3	7	3	0	10
Gamma-aminobutyric acid receptor subunit gamma-1	7	3	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	7	3	0	10
Gamma-aminobutyric acid receptor subunit alpha-4	7	3	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	7	3	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	7	3	0	10
Gamma-aminobutyric acid receptor subunit alpha-1	7	3	1	11
Gamma-aminobutyric acid receptor subunit beta-3	7	3	0	10
Gamma-aminobutyric acid receptor subunit beta-2	7	3	1	11
GABA theta subunit	7	3	0	10
Inositol hexakisphosphate kinase 1	10	0	0	10
Gamma-aminobutyric acid receptor subunit epsilon	7	3	0	10
Protein-arginine deiminase type-4	0	6	0	6
cytochrome P450 2C9, partial	10	0	0	10
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
cytochrome P450 2D6	6	0	0	6
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Smad3	1	0	0	1
Solute carrier family 22 member 6	0	6	0	6
Solute carrier family 22 member 6	0	7	0	7
Solute carrier family 22 member 8	0	5	0	5
Solute carrier family 22 member 11	0	2	0	2
Solute carrier family 22 member 8	0	4	0	5
Beta-lactamase	0	3	0	6
Beta-lactamase	0	3	0	5
Metallo-beta-lactamase VIM-19	0	0	0	7
Beta-lactamase	0	2	0	5
Albumin	0	1	5	6
Beta-lactamase	0	0	0	2
Beta-lactamase	0	2	0	5
Metallo-beta-lactamase VIM-2	0	0	0	6
Solute carrier family 22 member 7	0	1	0	1
BlaVIM-1	0	0	0	6
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	5
Solute carrier family 22 member 7	0	1	0	1
Solute carrier family 22 member 8	0	6	0	9
aldehyde dehydrogenase 1 family, member A1	12	0	0	12
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
streptokinase A precursor	0	0	6	6
lethal factor (plasmid)	4	0	0	4
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Beta-2 adrenergic receptor	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Dipeptidase 1	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
cytochrome P450 2C9 precursor	1	0	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	4	0	6
DNA gyrase subunit B	0	4	0	6
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	3	0	0	3
DNA gyrase subunit B	0	4	0	4
DNA gyrase subunit A	0	5	0	5
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	7
DNA topoisomerase 4 subunit A	0	2	0	2
DNA topoisomerase 4 subunit B	0	2	0	2
Integrase	0	1	0	1
Beta-lactamase TEM	0	6	0	9
15-lipoxygenase, partial	3	0	0	3
USP1 protein, partial	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	7	0	0	7
RAD51	0	1	0	1
Caspase-7	2	0	0	2
thyroid hormone receptor beta isoform a	4	0	0	4
caspase-3	2	0	0	2
huntingtin isoform 2	2	0	0	2
nuclear receptor ROR-gamma isoform 1	3	0	0	3
caspase-1 isoform alpha precursor	1	0	0	1
ATP-dependent translocase ABCB1	0	2	0	4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	1	0	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	3	0	3
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Ileal sodium/bile acid cotransporter	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Bile acid receptor	0	0	1	1
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	5	0	5
Cytochrome c oxidase subunit 2	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Transthyretin	0	0	1	3
Prostaglandin G/H synthase 1	0	2	0	2
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	5
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	3
Carbonic anhydrase 4	0	1	0	1
Multidrug and toxin extrusion protein 1	0	4	0	4
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Genome polyprotein	0	1	0	1
PPM1D protein	2	0	0	2
Tyrosine-protein kinase Fyn	0	1	0	1
NFKB1 protein, partial	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
flap endonuclease 1	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
Solute carrier family 22 member 1	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
D(2) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
D(4) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	2	1	3
D(3) dopamine receptor	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	2	0	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	3	0	3
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	2	0	2
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Histone deacetylase 1	0	2	0	2
Lanosterol 14-alpha demethylase	0	3	1	4
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
GALC protein	3	0	0	3
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
endonuclease IV	2	0	0	2
Skn7p	0	0	0	1
pregnane X receptor	1	0	0	1
Thrombopoietin	1	0	0	1
nonstructural protein 1	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Vpr	1	0	0	1
Epidermal growth factor receptor	0	1	0	1
Amyloid-beta precursor protein	1	0	0	1
Thymidylate synthase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, Type Iii Chloramphenicol Acetyltransferase	0	1	0	1
Estrogen receptor	0	0	2	2
Guanine nucleotide-binding protein G	2	0	0	2
Estrogen receptor beta	0	0	2	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
large T antigen	0	1	0	1
cytochrome P450 2D6 isoform 1	2	0	0	2
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Coagulation factor X	0	1	0	1
Plasminogen	0	2	0	2
Coagulation factor XII	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Serine protease hepsin	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
regulator of G-protein signaling 4	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
D(1A) dopamine receptor	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	3	0	7
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	3
Beta-lactamase	0	0	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Renin	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	1	3
Sodium-dependent serotonin transporter	0	0	1	1
Amine oxidase [flavin-containing] B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Glucocorticoid receptor	0	4	1	10
Glycine receptor subunit alpha-1	0	4	0	4
Androgen receptor	0	3	0	3
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Pyruvate kinase PKM	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	3
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Adenosine receptor A1	0	1	0	1
Caspase-1	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Caspase-9	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
MecA	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	2	0	3
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	3
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
dopamine D1 receptor	2	0	0	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Cytochrome P450 2B6	0	1	1	2
Arylacetamide deacetylase	0	1	0	2
Alpha-synuclein	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Solute carrier organic anion transporter family member 1B1	0	2	0	3
Beta-lactamase	0	2	0	2
Replicase polyprotein 1ab	0	1	0	1
Beta-lactamase OXA-1	0	2	0	3
5-hydroxytryptamine receptor 1A	0	2	0	2
Metallo-beta-lactamase type 2	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Dihydrofolate reductase	0	3	0	4
Endothelin-1 receptor	0	1	0	1
Protease	0	1	1	2
B2 bradykinin receptor	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase L1 type 3	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Protein Rev	0	0	1	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
cytochrome P450 2C19 precursor	1	0	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (146)

Protein Targets (743)

Abscess, Psoas

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (146)

Drugs Studied (103)

Protein Targets (743)