Erythrophagocytic Lymphohistiocytosis, Familial

Rare form of hemophagocytic lymphohistiocytosis with multiorgan involvement seen in infants and young children

Synonym
Hemophagocytic Lymphohistiocytosis Familial -1
Primary Hemophagocytic Lymphohistiocytosis
Familial Hemophagocytic Histiocytosis
Erythrophagocytic Lymphohistiocytosis, Familial
Reactive Hemophagocytic Syndrome
Hemophagocytic Syndrome, Infection-Associated
Hemophagocytic Syndrome, Reactive
Familial Erythrophagocytic Lymphohistiocytosis
Familial Hemophagocytic Lymphohistiocytosis
Hemophagocytic Syndromes
Primary Hemophagocytic Hymphohistiocytosis
Familial Hemophagocytic Reticulosis
Familial Histiocytic Reticulosis
Familial Hemophagocytic Lymphocytosis
Hemophagocytic Reticulosis, Familial
Hemophagocytic Lymphohistiocytosis, Familial, 1
Reticulosis, Familial Histiocytic
Hemophagocytic Lymphohistiocytosis, Familial
Hemophagocytic Syndrome

Excerpt	Reference
"Hemophagocytic syndrome is a rare complication of acute Q fever."	( Chang, K; Chen, TC; Chen, YH; Hsieh, HC; Lin, SF; Lin, WR; Liu, YC; Lu, PL; Tsai, JJ; Yang, WC, 2006)
"Familial hemophagocytic lymphohistiocytosis is a genetically determined condition that is characterized by unremitting CD8 T lymphocyte and macrophage activation and leads to death in the absence of therapy."	( Blanche, S; de Saint Basile, G; Fischer, A; Mahlaoui, N; Neven, B; Ouachée-Chardin, M; Picard, C, 2007)
"Hemophagocytic syndrome is a systemic reactive histiocytic proliferative disorder affecting the reticuloendothelial system."	( Iizuka, H; Miura, T; Otsubo, S; Sakai, H, 2007)
"Secondary or reactive hemophagocytic syndrome is frequently related to viral infections and is named Virus-Associated Hemophagocytic Syndrome (VAHS)."	( Halfon, P; Helbert, T; Mathieu, D; Pégliasco, H; Philibert, P; Retornaz, F, 2009)
"Familial hemophagocytic lymphohistiocytosis is a very unusual cause for demyelination and the clinician would do well to be aware of the condition, especially when children present with atypical findings on magnetic resonance imaging associated with fever, pancytopenia, and hepatosplenomegaly."	( Gibikote, S; Kumar, S; Moses, PD; Puliyel, MM; Rose, W, 2009)
"Hemophagocytic Syndrome is a clinical condition characterized by the activation of either macrophages or histiocytes with a prominent hemophagocytosis feature in the bone marrow and other reticuloendothelial systems."	( Botelho, C; Carreira, A; Ferrer, F; Francisco, L; Maia, P; Mendes, T, 2010)
"Hemophagocytic syndrome is a rare disease that is often fatal, despite treatment."	( Esch, GW; Hu, J; Yang, Y; Zuo, W; Zuo, Y, 2013)
"Hemophagocytic syndrome is a severe condition of excessive immune activation that has a high mortality in the absence of treatment."	( Beffermann C, N; Ocqueteau T, M; Pilcante S, J; Sarmiento M, M, 2015)
"Primary hemophagocytic lymphohistiocytosis is a rare syndrome characterized by immune dysregulation and hyperinflammation."	( Ahlmann, M; Allen, C; Ballabio, M; Cesaro, S; Dapena Diaz, JL; De Benedetti, F; de Min, C; Degar, B; Fagioli, F; Garrington, TP; Grom, A; Henry, M; Jacqmin, P; Jordan, MB; Lapeyre, G; Locatelli, F; Putti, MC; Rao, A; Rizzari, C; Sevilla, J, 2020)
"Primary hemophagocytic lymphohistiocytosis is a severe and uncommon disease affecting pediatric patients."	( Beltran, E; Builes, N; Cleves, D; Escobar-González, AF; Franco, AA; Medina-Valencia, D; Olaya, M, 2021)
"Familial hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammatory disease caused by genetic defects in the granule-mediated cytotoxic pathway."	( Bourbonnais, S; Bourdin, B; Decaluwe, H; Gaboury, L; Joly, JA; Patey, N; Théorêt, Y; Vallée, A, 2023)
"Hemophagocytic syndrome is a rare life-threatening disorder that can be triggered by various conditions such as HIV infection and opportunistic agents."	( Argy, N; Debus, J; Guiraud, V; Herbel, S; Ricard, JD; Roux, D; Tetelboum, N; Thy, M; Verney, C; Zucman, N, 2022)

Excerpt	Reference
"An infantile case of hemophagocytic syndrome (HPS) with systemic juvenile idiopathic arthritis (s-JIA), refractory to methylprednisolone pulse therapy and cyclosporine A administration, was successfully treated by plasma exchange."	( Ashida, A; Inoue, T; Matsumura, H; Murata, T; Nagatoya, K; Nakakura, H; Shibahara, N; Tamai, H, 2009)
"He was diagnosed as having familial hemophagocytic lymphohistiocytosis and treated with the HLH 2004 protocol."	( Gibikote, S; Kumar, S; Moses, PD; Puliyel, MM; Rose, W, 2009)
"Suspecting lymphoma-associated hemophagocytic syndrome (HPS), we administered high-dose steroid and combination chemotherapy."	( Aoyama, I; Hori, M; Ichida, S; Yoshida, R, 2009)
"To explore early diagnosis of hemophagocytic syndrome (HPS) and effective treatment."	( Cen, XN; Duan, XZ; Li, BT; Li, J; Ning, F; Wang, YN; Wang, Z; Wu, L, 2009)
"Primary or genetic hemophagocytic syndrome was suspected and immunosuppressive treatment (steroids and cyclosporin) was instituted."	( Barlogis, V; Baudesson de Chanville, A; Chambost, H; Loosveld, M; Visentin, S, 2013)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	130 (15.55)	18.1394
2010's	457 (54.67)	28.8240
2020's	249 (29.78)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	2	0
ammonium hydroxide	low	1	0
choline	low	1	0
chlorine	low	1	0
salicylic acid	low	2	0
methylmalonic acid	low	1	0
cytosine	low	1	0
lactic acid	low	1	0
glycine	low	1	0
glycerol	low	2	0
pyrazinamide	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
phenytoin	low	1	0
aspirin	low	2	0
azathioprine	low	23	0
bromhexine	low	1	0
busulfan	low	12	0
ciprofloxacin	low	2	0
citalopram	low	1	0
dapsone	low	2	0
deferoxamine	low	2	0
fluconazole	low	3	0
foscarnet	low	3	0
furosemide	low	1	0
gentamicin	low	1	0
hydroxychloroquine	low	8	0
ibuprofen	low	1	0
ifosfamide	low	1	0
indomethacin	low	2	0
isoniazid	low	1	0
lamotrigine	low	11	0
leflunomide	low	1	0
lomustine	low	2	0
mebendazole	low	1	0
metformin	low	1	0
metronidazole	low	1	0
mitoxantrone	low	2	0
nafamostat	low	1	0
ofloxacin	low	2	0
phenobarbital	low	1	0
phenylbutazone	low	1	0
primaquine	low	2	0
procarbazine	low	1	0
propofol	low	1	0
pyrimethamine	low	1	0
sulfadiazine	low	1	0
sulfamethizole	low	1	0
sulfamethoxazole	low	1	0
sulfasalazine	low	6	0
thalidomide	low	2	0
thiotepa	low	2	0
tranexamic acid	low	1	0
trimethoprim	low	2	0
prednisolone	low	60	0
prednisone	medium	51	4
alanine	low	5	0
chloramphenicol	low	1	0
aspartic acid	low	2	0
lysine	low	2	0
edetic acid	low	1	0
adenosine monophosphate	low	2	0
methylene blue	low	1	0
colchicine	low	2	0
oxacillin	low	1	0
ampicillin	low	1	0
cytarabine	low	5	0
asparagine	low	1	0
valine	low	3	0
arginine	low	1	0
methylprednisolone	medium	70	2
penicillanic acid	low	2	0
pyrroles	low	1	0
meglumine	low	1	0
cyclopentane	low	1	0
thiazoles	low	1	0
dexamethasone 21-phosphate	low	2	0
azacitidine	low	2	0
betamethasone	low	1	0
alpha-aminopyridine	low	1	0
erythromycin	low	1	0
deoxycytidine	low	1	0
vancomycin	low	3	0
fluorescein-5-isothiocyanate	low	1	0
cladribine	low	2	0
vidarabine	medium	21	2
gadolinium	low	1	0
gold	low	2	0
trolamine salicylate	low	4	0
clodronic acid	low	1	0
tetradecanoylphorbol acetate	low	1	0
danazol	low	1	0
daunorubicin	low	2	0
cetylpyridinium chloride anhydrous	low	1	0
4-methoxyamphetamine	low	1	0
transferrin	low	1	0
amoxicillin	low	1	0
enterobactin	low	1	0
oxcarbazepine	low	1	0
etoposide	medium	183	7
ribavirin	low	3	0
amikacin	low	3	0
epirubicin	low	1	0
idarubicin	low	2	0
piperacillin	low	2	0
cefoperazone	low	1	0
itraconazole	low	3	0
cidofovir anhydrous	low	4	0
gemcitabine	low	1	0
lamivudine	low	1	0
dexamethasone 21-palmitate	low	3	0
trimethoprim sulfamethizole	low	1	0
meglumine antimoniate	low	1	0
oseltamivir	low	1	0
n-acetylaspartic acid	low	1	0
cephalosporin c	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	19	0
artemisinin	low	1	0
artemether	low	1	0
voriconazole	low	2	0
atovaquone	low	3	0
bendamustine hydrochloride	low	1	0
rosiglitazone	low	1	0
n-hydroxysuccinimide	low	1	0
clarithromycin	low	3	0
fibrinogen	low	21	0
imipenem, anhydrous	low	4	0
artesunic acid	low	3	0
sivelestat	low	1	0
phorbol-12-myristate	low	1	0
caprylates	low	1	0
tazobactam	low	1	0
methotrexate	medium	25	1
pomalidomide	low	1	0
beta-lactams	low	1	0
10-propargyl-10-deazaaminopterin	low	2	0
levofloxacin	low	2	0
naproxen	low	1	0
aminopterin	low	2	0
biotin	low	1	0
organophosphonates	low	1	0
lenalidomide	low	3	0
lacosamide	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	6	0
fibrin	low	1	0
glucosamine	low	1	0
epiglucan	low	1	0
meropenem	low	5	0
yersiniabactin	low	1	0
tretinoin	low	3	0
tacrolimus	low	9	0
mycophenolic acid	low	6	0
clindamycin	low	2	0
zithromax	low	7	0
decitabine	low	1	0
dactinomycin	low	1	0
melphalan	medium	9	2
posaconazole	low	1	0
micafungin	low	1	0
artemisin	low	1	0
bucillamine	low	1	0
fludarabine	medium	19	2
propylthiouracil	low	1	0
mercaptopurine	low	8	0
methimazole	low	2	0
sphingosine	low	1	0
bilirubin	medium	12	1
amphotericin b	low	45	0
clavulanic acid	low	1	0
phenylephrine hydrochloride	low	1	0
hydromorphone	low	1	0
sirolimus	low	2	0
cysteine	low	2	0
phosphorus	low	1	0
cefepime	low	1	0
cefotaxime	low	1	0
proguanil	low	1	0
cilastatin	low	1	0
lumefantrine	low	1	0
sq-23377	medium	3	1
etoposide phosphate	low	1	0
mocetinostat	low	1	0
treosulfan	low	5	0
etimicin	low	1	0
tofacitinib	low	2	0
pazopanib	low	2	0
sitagliptin phosphate	low	1	0
trametinib	low	2	0
losartan potassium	low	1	0
peramivir	low	1	0
clove	low	2	0
cytochrome c-t	low	1	0
endothelin-1	low	1	0
phosphatidylcholines	low	1	0
sodium oxybate	low	1	0
ro13-9904	low	9	0
piperacillin, tazobactam drug combination	low	2	0
pci 32765	low	2	0
cabozantinib	low	1	0
incb-018424	medium	60	4
baricitinib	low	4	0
piperidines	low	4	0
interleukin-8	low	5	0
dabrafenib	low	2	0
colistin	low	1	0
natriuretic peptide, brain	low	1	0
minocycline	low	5	0
transforming growth factor beta	low	1	0
daptomycin	low	1	0
vitamin b 12	low	3	0
s 8932	low	2	0
cyclosporine	medium	113	1
technetium tc 99m medronate	low	1	0
thromboplastin	low	1	0
muramidase	low	1	0
exudates	low	2	0
entecavir	low	2	0
acyclovir	low	12	0
guanosine triphosphate	low	1	0
guanine	low	2	0
neopterin	low	8	0
rifampin	low	5	0
dacarbazine	low	7	0
ganciclovir	low	18	0
allopurinol	low	1	0
valganciclovir	low	2	0
aprepitant	low	1	0
eye	low	1	0
antimony sodium gluconate	low	1	0
pyrimidinones	low	2	0

Protein Targets (2,018)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	5	0	0	5
thioredoxin reductase	27	0	0	27
USP1 protein, partial	28	0	0	28
TDP1 protein	68	0	0	68
vitamin D3 receptor isoform VDRA	20	0	0	20
importin subunit beta-1 isoform 1	8	0	0	8
flap endonuclease 1	11	0	0	11
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	8	0	0	8
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
DNA polymerase eta isoform 1	8	0	0	8
DNA polymerase iota isoform a (long)	22	0	0	22
urokinase-type plasminogen activator precursor	17	0	0	17
plasminogen precursor	17	0	0	17
urokinase plasminogen activator surface receptor precursor	17	0	0	17
geminin	67	0	0	67
DNA polymerase kappa isoform 1	17	0	0	17
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	2	3	5
Beta-lactamase	0	4	0	4
Transthyretin	0	1	1	2
Fatty acid-binding protein, intestinal	0	2	1	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	3	11	14
Choline O-acetyltransferase	0	2	0	2
Mitogen-activated protein kinase 12	0	2	3	5
Guanine nucleotide-binding protein G	7	0	0	7
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	2	9	11
Mitogen-activated protein kinase 14	0	2	9	11
Fumarate hydratase	24	0	0	24
AR protein	70	0	0	70
EWS/FLI fusion protein	58	0	0	58
estrogen nuclear receptor alpha	86	0	0	86
polyprotein	24	0	0	24
thyroid hormone receptor beta isoform 2	54	0	0	54
Dihydrofolate reductase	0	15	0	16
Cellular tumor antigen p53	47	0	0	47
Folate receptor alpha	0	3	0	3
Reduced folate transporter	0	4	0	4
Spike glycoprotein	37	0	4	41
Proton-coupled folate transporter	0	4	0	5
ATPase family AAA domain-containing protein 5	28	0	0	28
Ataxin-2	33	0	0	33
5-hydroxytryptamine receptor 2C	0	5	1	8
5-hydroxytryptamine receptor 2A	0	7	1	8
5-hydroxytryptamine receptor 1A	0	8	1	9
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 2B	0	5	1	6
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	10	2	12
Sodium-dependent serotonin transporter	0	5	0	5
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	14	0	0	14
Chain B, HADH2 protein	14	0	0	14
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Chain A, Ferritin light chain	18	0	0	18
Thymidine kinase	0	3	0	3
phosphopantetheinyl transferase	25	0	0	25
GLS protein	18	0	0	18
Smad3	13	0	0	13
thyroid stimulating hormone receptor	22	0	0	22
arylsulfatase A	17	0	0	17
euchromatic histone-lysine N-methyltransferase 2	50	0	0	50
activating transcription factor 6	23	0	0	23
Histone H2A.x	27	0	0	27
Bloom syndrome protein isoform 1	25	0	0	25
hemoglobin subunit beta	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
lamin isoform A-delta10	53	0	0	53
Solute carrier family 22 member 1	0	7	0	11
ATP-binding cassette sub-family C member 3	0	72	0	72
Multidrug resistance-associated protein 4	0	72	0	73
Solute carrier family 22 member 6	0	11	0	13
Bile salt export pump	0	16	0	16
Bile salt export pump	0	87	0	87
Purine nucleoside phosphorylase	0	3	0	3
Thymidine kinase, cytosolic	0	1	0	3
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2C9	0	26	2	29
Cytochrome P450 2J2	0	13	0	13
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Purine nucleoside phosphorylase	0	0	4	4
Solute carrier family 22 member 6	0	10	0	14
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	8	0	10
Canalicular multispecific organic anion transporter 1	0	70	0	71
Thymidine kinase	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	30	0	0	30
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	48	0	0	48
nuclear receptor subfamily 1, group I, member 3	43	0	0	43
cytochrome P450 family 3 subfamily A polypeptide 4	44	0	0	44
glucocorticoid receptor [Homo sapiens]	48	0	0	48
estrogen-related nuclear receptor alpha	63	0	0	63
pregnane X nuclear receptor	44	0	0	44
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	31	0	0	31
nuclear factor erythroid 2-related factor 2 isoform 2	24	0	0	24
heat shock protein beta-1	19	0	0	19
tumor susceptibility gene 101 protein	3	0	0	3
Voltage-dependent calcium channel gamma-2 subunit	30	0	0	30
Cyclin-dependent kinase 1	0	1	9	10
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	31	1	0	32
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	14	1	0	15
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	3	5
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
regulator of G-protein signaling 4	9	0	0	9
v-jun sarcoma virus 17 oncogene homolog (avian)	24	0	0	24
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	2
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	2	3
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	5	9	14
Amine oxidase [flavin-containing] B	0	2	0	2
5'-nucleotidase	0	1	0	2
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	2	1	3
Adenylate kinase isoenzyme 1	0	1	0	2
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	11	12
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	4	5
Adenylate kinase 2, mitochondrial	0	0	9	10
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	11	12
Adenosine deaminase-like protein	0	0	0	1
Protease	0	4	2	6
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	10	11
5'-AMP-activated protein kinase subunit beta-1	0	0	2	3
ATP-dependent phosphofructokinase	21	0	0	21
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	18	0	0	18
Carbonic anhydrase 1	0	12	0	17
Carbonic anhydrase 2	0	14	1	19
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	5	2	8
Proton-coupled amino acid transporter 1	0	2	0	2
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	2
glp-1 receptor, partial	16	0	0	16
NPYLR7B	0	0	2	2
thyroid stimulating hormone receptor	21	0	0	21
peripheral myelin protein 22	27	0	0	27
Beta-2 adrenergic receptor	0	2	2	4
Beta-1 adrenergic receptor	0	0	2	2
60 kDa chaperonin	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	7	0	7
Beta-3 adrenergic receptor	0	2	1	3
Delta-type opioid receptor	0	2	1	3
10 kDa heat shock protein, mitochondrial	0	7	0	7
Thiosulfate sulfurtransferase	0	7	0	7
Beta-2 adrenergic receptor	0	0	1	3
60 kDa chaperonin	0	7	0	7
10 kDa chaperonin	0	7	0	7
Beta-2 adrenergic receptor	0	1	2	3
interleukin 8	18	0	0	18
estrogen receptor 2 (ER beta)	27	0	0	27
progesterone receptor	30	0	0	30
IDH1	22	0	0	22
transcriptional regulator ERG isoform 3	9	0	0	9
ras-related protein Rab-9A	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	53	0	0	53
survival motor neuron protein isoform d	23	0	0	23
Polyphenol oxidase 2	0	5	0	7
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	3
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	2	1	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	1	0	6
retinoic acid nuclear receptor alpha variant 1	44	0	0	44
Heat shock protein HSP 90-alpha	0	0	1	1
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	1	1	4
Kappa-type opioid receptor	0	1	1	7
Phosphatidylinositol 4-kinase alpha	0	1	0	1
Mu-type opioid receptor	0	3	1	4
Tyrosine-protein kinase	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	1	0	1
Phosphatidylinositol 4-kinase type 2-alpha	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	1	3	4
histone acetyltransferase KAT2A isoform 1	16	0	0	16
Aminoglycoside 3'-phosphotransferase	0	0	0	1
hypoxia-inducible factor 1 alpha subunit	20	0	0	20
SMAD family member 2	14	0	0	14
SMAD family member 3	14	0	0	14
retinoid X nuclear receptor alpha	42	0	0	42
farnesoid X nuclear receptor	37	0	0	37
peroxisome proliferator-activated receptor delta	35	0	0	35
peroxisome proliferator activated receptor gamma	34	0	0	34
vitamin D (1,25- dihydroxyvitamin D3) receptor	33	0	0	33
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	16	0	0	16
Dihydrofolate reductase	0	6	0	8
Dihydrofolate reductase	0	6	0	8
Dihydrofolate reductase	0	10	3	14
Folylpolyglutamate synthase, mitochondrial	0	2	0	5
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	5
Chain A, Beta-lactamase	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	22	0	0	22
Beta-lactamase	0	2	0	4
Beta-lactamase	0	2	0	7
Beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	7
apical membrane antigen 1, AMA1	9	0	0	9
Beta-lactamase	0	0	0	3
Beta-lactamase SHV-1	0	2	0	5
Beta-lactamase SHV-1	0	4	0	10
Beta-lactamase	0	2	0	8
Solute carrier family 15 member 1	0	7	0	7
Solute carrier family 15 member 1	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	5
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	2	0	5
Beta-lactamase	0	1	0	5
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	2	0	5
Beta-lactamase	0	0	0	5
Chain A, Cruzipain	9	0	0	9
tumor necrosis factor	1	0	0	1
Cytochrome P450 1A2	0	9	1	10
Cytochrome P450 3A4	0	23	2	28
Cytochrome P450 2D6	0	9	1	10
Cytochrome P450 2C19	0	9	1	11
Nuclear receptor ROR-gamma	13	1	1	15
Potassium voltage-gated channel subfamily H member 2	0	29	0	30
Aurora kinase B	0	1	9	10
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	11	0	14
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	3	0	7
GLI family zinc finger 3	50	0	0	50
Beta-lactamase	0	2	0	6
Beta-lactamase	0	1	0	7
Metallo-beta-lactamase type 2	0	0	1	7
Metallo-beta-lactamase VIM-11	0	0	0	5
Metallo-beta-lactamase VIM-2	0	0	0	5
Beta-lactamase	0	0	0	6
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	14	0	0	14
chromobox protein homolog 1	29	0	0	29
DNA polymerase beta	6	0	0	6
Beta-lactamase OXA-7	0	0	0	3
Angiopoietin-1 receptor	0	1	4	5
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Metallo-beta-lactamase VIM-13	0	1	0	7
Efflux transporter	0	0	0	1
Beta-lactamase	0	1	0	6
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	2	0	5
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	7
Beta-lactamase	0	0	1	5
Metallo-b-lactamase	0	0	0	8
Carbapenem-hydrolyzing beta-lactamase KPC	0	4	0	9
Beta-lactamase class B VIM-2	0	0	1	9
Beta-lactamase VIM-1	0	1	0	7
GALC protein	9	0	0	9
caspase 7, apoptosis-related cysteine protease	12	0	0	12
G	35	0	0	35
cytochrome P450 2D6	23	0	0	23
caspase-3	12	0	0	12
Interferon beta	49	0	0	49
HLA class I histocompatibility antigen, B alpha chain	35	0	0	35
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	0	1
cGMP-dependent protein kinase 1	0	0	10	10
Substance-P receptor	0	1	0	1
Inositol hexakisphosphate kinase 1	35	0	0	35
cytochrome P450 2C9, partial	35	0	0	35
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	8	0	0	8
alpha-galactosidase	4	0	0	4
cytochrome P450 2C19 precursor	7	0	0	7
muscarinic acetylcholine receptor M1	14	0	0	14
lethal factor (plasmid)	14	0	0	14
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, inducible	0	1	0	2
Cationic amino acid transporter 3	0	2	0	2
nonstructural protein 1	9	0	0	9
Dihydroorotate dehydrogenase	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	1	0	1
aldehyde dehydrogenase 1 family, member A1	40	0	0	40
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	6
Glutamate receptor ionotropic, NMDA 2B	0	5	1	7
Glutamate receptor ionotropic, NMDA 2C	0	4	1	6
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	4	1	6
Glutamate receptor ionotropic, NMDA 3B	0	4	1	6
Glutamate receptor ionotropic, NMDA 3A	0	4	1	6
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	3	0	0	3
glucocerebrosidase	6	0	0	6
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	5
Prostaglandin G/H synthase 2	0	3	0	4
Epidermal growth factor receptor	0	8	10	18
Fatty acid-binding protein, liver	0	3	0	3
Integrin beta-3	10	2	0	12
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	8	0	9
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	10	2	0	12
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	9	0	9
Adenosine receptor A1	0	5	0	5
Adenosine receptor A2a	0	4	0	4
Substance-P receptor	0	3	0	3
Prostaglandin G/H synthase 2	0	10	4	14
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	24	5	1	30
Prostaglandin G/H synthase 2	0	7	0	7
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	4	0	4
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	7	1	8
Sigma non-opioid intracellular receptor 1	0	4	1	5
Microtubule-associated protein tau	21	0	0	21
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
aryl hydrocarbon receptor	25	0	0	25
Dihydroorotate dehydrogenase	0	1	0	1
cellular tumor antigen p53 isoform a	12	0	0	12
cytochrome P450 2C9 precursor	11	0	0	11
potassium voltage-gated channel subfamily H member 2 isoform d	12	0	0	12
nuclear receptor ROR-gamma isoform 1	18	0	0	18
Vpr	4	0	0	4
Cytochrome b	0	1	0	1
Dihydroorotate dehydrogenase (fumarate)	0	1	0	1
Histamine H2 receptor	15	0	0	16
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	2	0	3
Dihydroorotate dehydrogenase	0	2	0	2
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	2	0	3
pregnane X receptor	8	0	0	8
ATAD5 protein, partial	14	0	0	14
PPM1D protein	19	0	0	19
Thrombopoietin	6	0	0	6
67.9K protein	23	0	0	23
Parkin	7	0	0	7
peripheral myelin protein 22 isoform 1	10	0	0	10
huntingtin isoform 2	9	0	0	9
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
Adenosine receptor A3	0	6	0	6
DNA (cytosine-5)-methyltransferase 1	0	2	0	2
D(1A) dopamine receptor	4	1	0	5
Multidrug and toxin extrusion protein 1	0	7	0	7
Histone-lysine N-methyltransferase EHMT2	0	2	0	2
acetylcholinesterase	18	0	0	18
thioredoxin glutathione reductase	8	0	0	8
P53	2	0	0	2
cytochrome P450 3A4 isoform 1	24	0	0	24
M-phase phosphoprotein 8	7	0	0	7
muscleblind-like protein 1 isoform 1	12	0	0	12
Gamma-aminobutyric acid receptor subunit pi	24	4	1	29
Gamma-aminobutyric acid receptor subunit beta-1	24	4	1	29
Gamma-aminobutyric acid receptor subunit delta	24	4	1	29
Gamma-aminobutyric acid receptor subunit gamma-2	24	4	1	29
Gamma-aminobutyric acid receptor subunit alpha-5	24	4	1	29
Gamma-aminobutyric acid receptor subunit alpha-3	24	4	1	29
Gamma-aminobutyric acid receptor subunit gamma-1	24	4	1	29
Gamma-aminobutyric acid receptor subunit alpha-2	24	4	1	29
Gamma-aminobutyric acid receptor subunit alpha-4	24	4	1	29
Gamma-aminobutyric acid receptor subunit gamma-3	24	4	1	29
Gamma-aminobutyric acid receptor subunit alpha-6	24	4	1	29
Gamma-aminobutyric acid receptor subunit beta-3	24	4	1	29
Gamma-aminobutyric acid receptor subunit beta-2	24	4	1	29
GABA theta subunit	24	4	1	29
Gamma-aminobutyric acid receptor subunit epsilon	24	4	1	29
Protein-arginine deiminase type-4	0	9	0	9
Bone morphogenetic protein receptor type-1B	0	0	9	9
Membrane-associated progesterone receptor component 1	0	0	6	6
Serine/threonine-protein kinase PLK4	0	0	9	9
ATP-dependent RNA helicase DDX3X	0	0	9	9
Pyridoxal kinase	0	0	9	9
Citron Rho-interacting kinase	0	0	9	9
Serine/threonine-protein kinase Chk1	0	1	9	10
Aurora kinase A	0	1	9	10
Cyclin-G-associated kinase	0	2	9	11
Ephrin type-B receptor 6	0	0	9	9
Peroxisomal acyl-coenzyme A oxidase 3	0	0	9	9
Receptor-interacting serine/threonine-protein kinase 2	0	1	9	10
Dynamin-like 120 kDa protein, mitochondrial	0	0	9	9
Tyrosine-protein kinase JAK2	0	8	9	20
Eukaryotic translation initiation factor 5B	0	0	6	6
Rho-associated protein kinase 2	0	1	9	10
Serine/threonine-protein kinase ULK1	0	0	9	9
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	9	9
Ribosomal protein S6 kinase alpha-5	0	1	9	10
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	9	9
Ribosomal protein S6 kinase alpha-4	0	0	9	9
Serine/threonine-protein kinase 16	0	0	9	9
Serine/threonine-protein kinase 10	0	0	9	9
Serine/threonine-protein kinase D3	0	0	10	10
Structural maintenance of chromosomes protein 2	0	0	8	8
Mitogen-activated protein kinase kinase kinase 6	0	0	9	9
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	9	9
Serine/threonine-protein kinase LATS1	0	0	9	9
Serine/threonine-protein kinase PAK 4	0	0	9	9
Tyrosine-protein kinase ABL1	0	3	10	15
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	7	7
ADP/ATP translocase 2	0	0	9	9
Protein kinase C beta type	0	1	10	11
Insulin receptor	0	1	9	10
Tyrosine-protein kinase Lck	0	2	9	11
Tyrosine-protein kinase Fyn	0	3	9	12
Glycogen phosphorylase, liver form	0	0	9	9
Tyrosine-protein kinase Fes/Fps	0	0	9	9
Adenine phosphoribosyltransferase	0	0	6	6
Tyrosine-protein kinase Yes	0	1	9	10
Tyrosine-protein kinase Lyn	0	1	9	10
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	9	12
Insulin-like growth factor 1 receptor	0	1	9	10
Signal recognition particle receptor subunit alpha	0	0	8	8
Cytochrome c1, heme protein, mitochondrial	0	0	9	9
Hepatocyte growth factor receptor	0	1	9	11
Tyrosine-protein kinase HCK	0	1	9	10
Platelet-derived growth factor receptor beta	0	2	9	11
Serine/threonine-protein kinase A-Raf	0	1	9	10
Glycogen phosphorylase, brain form	0	0	9	9
Breakpoint cluster region protein	0	0	9	11
Serine/threonine-protein kinase pim-1	0	1	9	10
Fibroblast growth factor receptor 1	0	2	9	11
DNA topoisomerase 2-alpha	0	3	8	21
Cyclin-dependent kinase 4	0	0	9	9
ADP/ATP translocase 3	0	0	9	9
Inosine-5'-monophosphate dehydrogenase 2	0	2	8	10
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	8	8
Serine/threonine-protein kinase B-raf	0	1	10	12
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	9	9
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	9	10
Tyrosine-protein kinase Fer	0	0	9	9
Protein kinase C alpha type	0	2	10	12
cAMP-dependent protein kinase catalytic subunit alpha	0	0	9	9
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	9	9
Casein kinase II subunit alpha'	0	1	9	10
Ras-related protein Rab-6A	0	0	7	7
Ephrin type-A receptor 1	0	0	8	8
Multifunctional protein ADE2	0	0	9	9
cAMP-dependent protein kinase catalytic subunit gamma	0	0	8	8
cAMP-dependent protein kinase catalytic subunit beta	0	0	9	9
Ferrochelatase, mitochondrial	0	0	9	9
Ribosomal protein S6 kinase beta-1	0	1	9	10
Tyrosine-protein kinase JAK1	0	8	11	22
Beta-adrenergic receptor kinase 1	0	0	9	9
Probable ATP-dependent RNA helicase DDX6	0	0	9	9
Mitogen-activated protein kinase 3	0	0	9	9
MAP/microtubule affinity-regulating kinase 3	0	0	9	9
Deoxycytidine kinase	0	0	9	13
Mitogen-activated protein kinase 1	0	2	9	11
Ephrin type-A receptor 2	0	1	9	10
Ephrin type-B receptor 2	0	0	9	9
Non-receptor tyrosine-protein kinase TYK2	0	6	11	20
UMP-CMP kinase	0	0	5	5
Phosphatidylethanolamine-binding protein 1	0	0	8	8
Wee1-like protein kinase	0	0	9	9
Heme oxygenase 2	0	0	9	9
S-adenosylmethionine synthase isoform type-2	0	0	9	9
DnaJ homolog subfamily A member 1	0	0	9	9
RAC-alpha serine/threonine-protein kinase	0	1	9	10
RAC-beta serine/threonine-protein kinase	0	0	9	9
DNA replication licensing factor MCM4	0	0	8	8
Myosin-10	0	0	7	7
Dual specificity mitogen-activated protein kinase kinase 2	0	3	9	12
Receptor-type tyrosine-protein kinase FLT3	0	3	9	12
Bone morphogenetic protein receptor type-1A	0	0	9	9
Activin receptor type-1B	0	0	9	9
TGF-beta receptor type-1	0	1	9	10
Serine/threonine-protein kinase receptor R3	0	0	7	7
TGF-beta receptor type-2	0	0	9	9
Electron transfer flavoprotein subunit beta	0	0	6	6
Tyrosine-protein kinase CSK	0	2	9	11
Glycine--tRNA ligase	0	0	9	9
Protein kinase C iota type	0	0	10	10
Exosome RNA helicase MTR4	0	0	9	9
Tyrosine-protein kinase Tec	0	2	9	11
Tyrosine-protein kinase ABL2	0	0	9	9
Tyrosine-protein kinase FRK	0	1	9	10
G protein-coupled receptor kinase 6	0	0	5	5
Tyrosine-protein kinase SYK	0	1	9	10
26S proteasome regulatory subunit 6B	0	0	9	9
Mitogen-activated protein kinase 8	0	1	9	10
Mitogen-activated protein kinase 9	0	0	9	9
Dual specificity mitogen-activated protein kinase kinase 3	0	0	9	9
Casein kinase I isoform alpha	0	0	8	8
Casein kinase I isoform delta	0	0	9	9
MAP kinase-activated protein kinase 2	0	1	9	10
Elongation factor Tu, mitochondrial	0	0	9	9
Cysteine--tRNA ligase, cytoplasmic	0	0	8	8
Casein kinase I isoform epsilon	0	0	9	9
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	9	9
Dual specificity protein kinase CLK1	0	0	9	9
Dual specificity protein kinase CLK2	0	0	9	9
Dual specificity protein kinase CLK3	0	0	8	8
Glycogen synthase kinase-3 alpha	0	0	9	9
Glycogen synthase kinase-3 beta	0	1	9	10
Cyclin-dependent kinase 7	0	0	9	9
Cyclin-dependent kinase 9	0	0	9	9
Ras-related protein Rab-27A	0	0	8	8
Interleukin-1 receptor-associated kinase 1	0	0	9	9
Ribosomal protein S6 kinase alpha-3	0	1	9	10
Serine/threonine-protein kinase Nek2	0	0	9	9
Serine/threonine-protein kinase Nek3	0	0	9	9
Tyrosine-protein kinase JAK3	0	7	5	16
Dual specificity mitogen-activated protein kinase kinase 6	0	0	9	9
LIM domain kinase 1	0	0	9	9
LIM domain kinase 2	0	0	9	9
Mitogen-activated protein kinase 10	0	0	9	9
Tyrosine--tRNA ligase, cytoplasmic	0	0	9	9
Ephrin type-B receptor 3	0	0	9	9
Ephrin type-A receptor 5	0	0	9	9
Ephrin type-B receptor 4	0	0	9	9
Ephrin type-A receptor 4	0	0	9	9
Adenosine kinase	0	0	9	9
Ras-related protein Rab-10	0	0	9	9
Actin-related protein 3	0	0	9	9
Actin-related protein 2	0	0	8	8
GTP-binding nuclear protein Ran	0	0	9	9
Casein kinase I isoform gamma-2	0	0	9	9
Cyclin-dependent kinase 3	0	0	8	8
Cyclin-dependent kinase 6	0	0	9	9
Cyclin-dependent-like kinase 5	0	1	9	10
Cyclin-dependent kinase 16	0	0	9	9
Cyclin-dependent kinase 17	0	0	9	9
ATP-dependent 6-phosphofructokinase, platelet type	0	0	9	9
Dual specificity mitogen-activated protein kinase kinase 1	0	2	9	11
DNA topoisomerase 2-beta	0	1	10	18
Protein kinase C theta type	0	0	10	10
Activin receptor type-1	0	0	9	9
Macrophage-stimulating protein receptor	0	1	9	10
Focal adhesion kinase 1	0	0	9	9
Protein kinase C delta type	0	1	10	11
Tyrosine-protein kinase BTK	0	4	10	14
Activated CDC42 kinase 1	0	0	9	9
Epithelial discoidin domain-containing receptor 1	0	0	9	9
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	9	9
Serine/threonine-protein kinase 4	0	0	9	9
Dual specificity mitogen-activated protein kinase kinase 5	0	0	9	9
Mitogen-activated protein kinase 7	0	0	9	9
Serine/threonine-protein kinase PAK 2	0	0	9	9
Serine/threonine-protein kinase 3	0	0	9	9
Mitogen-activated protein kinase kinase kinase 1	0	0	9	9
Integrin-linked protein kinase	0	0	9	9
Rho-associated protein kinase 1	0	0	9	9
Non-receptor tyrosine-protein kinase TNK1	0	0	9	9
Serine/threonine-protein kinase ATR	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	9	9
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	9	9
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	9	9
Activin receptor type-2B	0	0	9	9
Bone morphogenetic protein receptor type-2	0	0	9	9
Protein-tyrosine kinase 6	0	1	9	10
Cyclin-dependent kinase 13	0	0	9	9
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	9	9
Protein-tyrosine kinase 2-beta	0	0	9	9
Maternal embryonic leucine zipper kinase	0	0	9	9
Structural maintenance of chromosomes protein 1A	0	0	8	8
Chromodomain-helicase-DNA-binding protein 4	0	0	9	9
Peroxisomal acyl-coenzyme A oxidase 1	0	0	7	7
Ephrin type-A receptor 7	0	0	8	8
Delta(24)-sterol reductase	0	0	8	8
Ribosomal protein S6 kinase alpha-1	0	1	9	10
Dual specificity testis-specific protein kinase 1	0	0	7	7
Myosin light chain kinase, smooth muscle	0	0	9	9
Serine/threonine-protein kinase STK11	0	0	9	9
Serine/threonine-protein kinase N1	0	0	9	9
Serine/threonine-protein kinase N2	0	0	9	9
Calcium/calmodulin-dependent protein kinase type IV	0	0	9	9
Mitogen-activated protein kinase kinase kinase 11	0	0	9	9
MAP kinase-activated protein kinase 3	0	0	4	4
Discoidin domain-containing receptor 2	0	2	9	11
AP2-associated protein kinase 1	0	2	9	11
Myosin light chain kinase 3	0	0	9	9
Uncharacterized aarF domain-containing protein kinase 5	0	0	5	5
Putative heat shock protein HSP 90-beta 2	0	0	9	9
Rab-like protein 3	0	0	7	7
Serine/threonine-protein kinase MRCK alpha	0	0	9	9
Serine/threonine-protein kinase MRCK gamma	0	0	9	9
Acyl-CoA dehydrogenase family member 10	0	0	9	9
Serine/threonine-protein kinase ULK3	0	0	9	9
Uncharacterized protein FLJ45252	0	0	9	9
Acyl-CoA dehydrogenase family member 11	0	0	8	8
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	9	9
Serine/threonine-protein kinase MARK2	0	0	9	9
ATP-dependent RNA helicase DHX30	0	0	8	8
Serine/threonine-protein kinase TAO1	0	0	9	9
STE20-related kinase adapter protein alpha	0	0	9	9
Myosin-14	0	0	9	9
AarF domain-containing protein kinase 1	0	0	9	9
ATP-dependent RNA helicase DDX42	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	9	9
MAP kinase-activated protein kinase 5	0	1	9	10
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	5	5
Misshapen-like kinase 1	0	0	8	8
Atypical kinase COQ8A, mitochondrial	0	0	9	9
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	9	9
Mitogen-activated protein kinase 15	0	0	9	9
Serine/threonine-protein kinase Nek9	0	0	9	9
ATP-dependent RNA helicase DDX1	0	0	9	9
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	9	9
Calcium/calmodulin-dependent protein kinase type 1G	0	0	6	6
Serine/threonine-protein kinase Nek1	0	0	9	9
PAS domain-containing serine/threonine-protein kinase	0	0	7	7
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	9	9
EKC/KEOPS complex subunit TP53RK	0	0	9	9
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	9	9
Mitogen-activated protein kinase kinase kinase 5	0	0	9	9
Mitogen-activated protein kinase kinase kinase 3	0	0	9	9
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	9	9
Nucleolar GTP-binding protein 1	0	0	9	9
Serine/threonine-protein kinase D2	0	0	9	9
NUAK family SNF1-like kinase 2	0	0	8	8
RNA cytidine acetyltransferase	0	0	9	9
Serine/threonine-protein kinase SIK2	0	0	9	9
STE20-like serine/threonine-protein kinase	0	0	9	9
Serine/threonine-protein kinase TAO3	0	0	9	9
dCTP pyrophosphatase 1	0	0	9	9
Dual specificity protein kinase CLK4	0	0	9	9
Casein kinase I isoform gamma-1	0	0	9	9
Serine/threonine-protein kinase PAK 6	0	0	8	8
Phenylalanine--tRNA ligase beta subunit	0	0	9	9
Isoleucine--tRNA ligase, mitochondrial	0	0	7	7
BMP-2-inducible protein kinase	0	0	9	9
Obg-like ATPase 1	0	0	7	7
Midasin	0	0	9	9
Interleukin-1 receptor-associated kinase 4	0	0	9	9
Mitogen-activated protein kinase kinase kinase 20	0	0	9	9
Cyclin-dependent kinase 12	0	0	9	9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	8	8
Serine/threonine-protein kinase 26	0	0	9	9
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	8	8
Serine/threonine-protein kinase NLK	0	0	9	9
Serine/threonine-protein kinase TBK1	0	1	9	10
Septin-9	0	0	9	9
Ribosomal protein S6 kinase alpha-6	0	0	9	9
TRAF2 and NCK-interacting protein kinase	0	0	9	9
Serine/threonine-protein kinase TAO2	0	0	9	9
Long-chain-fatty-acid--CoA ligase 5	0	0	4	4
Serine/threonine-protein kinase ICK	0	0	9	9
RAC-gamma serine/threonine-protein kinase	0	0	9	9
Serine/threonine-protein kinase 38-like	0	0	4	4
Serine/threonine-protein kinase SIK3	0	0	9	9
Mitogen-activated protein kinase kinase kinase 2	0	0	9	9
Thyroid hormone receptor-associated protein 3	0	0	8	8
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	9	9
Receptor-interacting serine/threonine-protein kinase 3	0	1	9	10
Serine/threonine-protein kinase MRCK beta	0	0	9	9
Interleukin-1 receptor-associated kinase 3	0	0	9	9
Serine/threonine-protein kinase 24	0	0	9	9
Casein kinase I isoform gamma-3	0	0	9	9
Mitogen-activated protein kinase kinase kinase 4	0	0	9	9
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
thyroid hormone receptor beta isoform a	16	0	0	16
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
ORF73	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
caspase-1 isoform alpha precursor	4	0	0	4
Caspase-7	3	0	0	3
Inositol monophosphatase 1	9	0	0	9
Solute carrier organic anion transporter family member 1B3	0	13	0	16
Solute carrier organic anion transporter family member 1B1	0	11	0	13
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	2	0	2
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Angiotensin-converting enzyme	0	2	0	2
15-lipoxygenase, partial	9	0	0	9
Matrix metalloproteinase-9	0	5	0	5
tyrosine-protein kinase Yes	8	0	0	8
Cell division cycle 7-related protein kinase	0	0	6	6
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	8	8
High affinity nerve growth factor receptor	0	1	8	9
Acyl-CoA desaturase 1	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	2	3	5
Platelet-derived growth factor receptor alpha	0	2	3	5
Vascular endothelial growth factor receptor 1	0	2	3	5
Tyrosine-protein kinase receptor UFO	0	1	3	4
Kinesin-1 heavy chain	0	2	0	2
Dual specificity protein kinase TTK	0	0	8	8
Vascular endothelial growth factor receptor 3	0	2	3	5
Vascular endothelial growth factor receptor 2	0	4	3	8
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	7	7
Serine/threonine-protein kinase PLK1	0	0	8	8
Protein kinase C zeta type	0	0	5	5
Coiled-coil domain-containing protein 6	0	2	0	2
Serine/threonine-protein kinase Nek7	0	0	5	5
MAP/microtubule affinity-regulating kinase 4	0	0	8	8
SAFB-like transcription modulator	0	1	0	1
ALK tyrosine kinase receptor	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	8	8
Chain A, Beta-lactoglobulin	0	0	1	1
Chain A, Beta-lactoglobulin	0	0	1	1
UDP-3-O-acyl-N-acetylglucosamine deacetylase	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	7	0	0	7
Beta-lactamase	0	2	0	5
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	5
Beta-lactamase	0	2	0	5
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	2	0	3
Beta-lactamase	0	3	0	7
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	4	0	8
Beta-lactamase	0	1	0	2
Beta-lactamase	0	2	0	5
Metallo-beta-lactamase VIM-2	0	0	0	5
Beta-lactamase	0	0	0	3
BlaVIM-1	0	0	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	2	0	6
Glutathione reductase, mitochondrial	0	4	0	5
Glutathione peroxidase 1	0	1	0	1
Microsomal glutathione S-transferase 1	0	1	0	1
Solute carrier family 22 member 7	0	2	0	4
Solute carrier family 22 member 11	0	2	0	3
Solute carrier family 22 member 8	0	3	0	3
Solute carrier family 22 member 7	0	2	0	2
Beta-lactamase	0	3	0	4
Albumin	0	4	9	13
Beta-lactamase	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
thyrotropin-releasing hormone receptor	5	0	0	5
mitogen-activated protein kinase 1	11	0	0	11
Caspase-2	0	0	1	1
streptokinase A precursor	0	0	9	9
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
50S ribosomal protein L36 2	0	3	1	4
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase 4	0	5	0	6
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 15	0	3	0	3
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	5	0	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	1	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Thymidine kinase	0	0	0	1
Beta-2 adrenergic receptor	0	3	0	3
Beta-1 adrenergic receptor	0	3	0	3
Dipeptidase 1	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	3	0	6
DNA gyrase subunit B	0	3	0	6
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	4	0	5
DNA gyrase subunit A	0	5	0	6
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	3	0	3
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
D(1A) dopamine receptor	6	0	0	6
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	8	0	8
Aldo-keto reductase family 1 member B1	0	12	0	12
Tryptophan 5-hydroxylase 1	0	1	0	1
Angiotensin-converting enzyme	0	5	0	5
Aldo-keto reductase family 1 member B1	0	3	0	3
Aromatase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	12	1	13
Sodium-dependent dopamine transporter	0	3	0	3
Alpha-1D adrenergic receptor	0	6	0	6
5-hydroxytryptamine receptor 2C	0	8	0	8
Histamine H1 receptor	0	4	0	4
5-hydroxytryptamine receptor 2B	0	8	0	8
5-hydroxytryptamine receptor 7	0	3	0	3
Sodium-dependent dopamine transporter	0	5	0	5
Sigma intracellular receptor 2	0	5	0	5
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Transporter	0	3	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
relaxin receptor 1 isoform 1	1	0	0	1
bcl-2-like protein 11 isoform 1	0	0	2	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
Adenosine receptor A3	0	2	0	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
ATP-dependent translocase ABCB1	0	14	2	23
Beta-lactamase	0	2	0	2
Neutrophil elastase	0	4	0	5
Beta-lactamase OXA-1	0	2	0	3
Cytochrome P450 2B6	0	5	1	7
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	2	0	2
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Stromelysin-1	0	2	1	3
Macrophage metalloelastase	0	1	0	1
Luciferase	17	0	0	17
endonuclease IV	7	0	0	7
PAX8	0	0	0	1
cytochrome P450 2D6 isoform 1	8	0	0	8
nuclear receptor subfamily 0 group B member 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
steroidogenic factor 1	0	1	0	1
neuropeptide S receptor isoform A	5	0	0	5
Solute carrier family 22 member 3	0	3	0	4
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	3	2	6
ATP-dependent translocase ABCB1	0	5	0	5
Tubulin beta chain	0	3	2	6
Tubulin alpha-3C chain	0	3	2	6
ATP-dependent translocase ABCB1	0	5	0	5
Tubulin alpha-1B chain	0	3	2	6
Tubulin alpha-4A chain	0	3	2	6
Tubulin beta-4B chain	0	3	2	6
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	3	2	6
Tubulin beta-2A chain	0	3	2	6
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	3	2	6
Tubulin beta-2B chain	0	3	0	3
Tubulin alpha-3E chain	0	3	2	6
Tubulin alpha-1A chain	0	3	2	6
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	3	2	6
Tubulin beta-6 chain	0	3	2	6
Tubulin beta-2B chain	0	3	2	6
Tubulin beta-1 chain	0	3	2	6
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	3	0	4
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Pirin	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Cyclin-dependent kinase-like 5	0	0	6	6
GTPase KRas	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	1	3	5
Tyrosine-protein kinase Fgr	0	1	6	7
Dual specificity mitogen-activated protein kinase kinase 4	0	0	5	5
Choline-phosphate cytidylyltransferase A	0	0	4	4
Heat shock factor protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 1	0	2	3	5
Cyclin-dependent kinase 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	5	5
Dual serine/threonine and tyrosine protein kinase	0	1	3	4
Dual specificity testis-specific protein kinase 2	0	0	4	4
Serine/threonine-protein kinase pim-2	0	0	5	5
Isocitrate lyase	0	2	0	2
RAD51	0	1	0	1
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	2	0	2
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	3	3	6
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
Rap guanine nucleotide exchange factor 3	4	0	0	4
Estrogen receptor	0	4	0	4
Sex hormone-binding globulin	0	0	1	1
Alpha-2A adrenergic receptor	0	6	0	6
Androgen receptor	0	7	0	7
Alpha-1B adrenergic receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	5	0	5
Muscarinic acetylcholine receptor M3	0	4	0	4
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	4	0	5
5-hydroxytryptamine receptor 2A	0	4	0	4
Mu-type opioid receptor	0	5	2	7
D(3) dopamine receptor	0	4	1	7
Kappa-type opioid receptor	0	3	1	4
Alpha-1A adrenergic receptor	0	8	0	8
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
Dihydrofolate reductase	0	9	0	10
5-hydroxytryptamine receptor 6	0	2	0	2
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
Carbonyl reductase [NADPH] 1	0	0	0	2
Glutamate receptor 1	2	1	0	3
Glutamate receptor 3	2	1	0	3
Glutamate receptor 4	2	1	0	3
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	4	0	6
Histone deacetylase 1	0	4	0	4
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	4	0	4
exodeoxyribonuclease V subunit RecD	0	3	0	3
exodeoxyribonuclease V subunit RecB	0	3	0	3
exodeoxyribonuclease V subunit RecC	0	3	0	3
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
Eyes absent homolog 2	0	1	0	1
Amyloid-beta precursor protein	2	3	0	6
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Capsid protein	0	1	2	3
Genome polyprotein	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	5
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
Motilin receptor	0	1	1	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Lanosterol 14-alpha demethylase	0	5	1	6
Prothrombin	0	3	0	5
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
DNA topoisomerase 2	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	2
Serum paraoxonase/arylesterase 1	0	4	0	4
Caspase-3	0	3	0	3
DNA topoisomerase 2-alpha	0	0	0	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
Histone deacetylase 3	0	3	0	3
Chymotrypsinogen A	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	3	4
Aromatase	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B2, mitochondrial	0	2	0	2
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	2	0	2
Cytochrome P450 144	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	0	3	3
Sterol 14-alpha demethylase	0	2	2	4
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
14-alpha sterol demethylase	0	0	3	3
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
glycogen synthase kinase-3 beta isoform 1	0	0	3	3
Adenosine deaminase	0	0	0	2
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
DNA polymerase delta catalytic subunit	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	4	0	5
Carbonic anhydrase 9	0	5	0	6
Carbonic anhydrase 12	0	3	0	4
Carbonic anhydrase 3	0	3	0	3
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Carbonic anhydrase 6	0	4	0	5
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase 7	0	3	0	4
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
Carbonic anhydrase 13	0	2	0	3
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Carbonic anhydrase 14	0	3	0	4
Carbonic anhydrase 5B, mitochondrial	0	3	0	4
ClpP	2	0	0	2
Transitional endoplasmic reticulum ATPase	0	1	0	1
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Spike glycoprotein	0	0	4	4
Replicase polyprotein 1ab	0	1	5	6
Transmembrane protease serine 2	0	0	4	4
Procathepsin L	0	2	4	6
Replicase polyprotein 1a	0	0	4	4
Replicase polyprotein 1ab	0	0	4	4
Replicase polyprotein 1ab	0	2	4	6
Replicase polyprotein 1ab	0	3	4	7
Equilibrative nucleoside transporter 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	4	4
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Guanine deaminase	0	0	0	1
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
Adenylate cyclase type 1	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	8	0	8
Potassium channel subfamily K member 2	0	1	0	1
Albumin	0	0	2	2
Major prion protein	0	0	1	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	4	0	4
Muscarinic acetylcholine receptor M1	0	2	1	3
Muscarinic acetylcholine receptor M3	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	1	3
5-hydroxytryptamine receptor 1A	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	1	3
Muscarinic acetylcholine receptor M5	0	3	0	3
Muscarinic acetylcholine receptor M2	0	2	1	3
Muscarinic acetylcholine receptor M1	0	5	0	5
Integrin alpha-4	0	2	0	2
D(2) dopamine receptor	0	2	1	5
D	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	1	5
D(1B) dopamine receptor	0	2	0	3
Adenylate cyclase type 3	0	1	0	1
Alpha-2C adrenergic receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 3A	0	1	0	1
Histamine H2 receptor	0	2	0	2
D(1B) dopamine receptor	0	2	0	2
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
D(4) dopamine receptor	0	2	0	2
Histamine H1 receptor	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Kappa-type opioid receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	3	0	5
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	8	0	8
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	8	0	8
Voltage-dependent L-type calcium channel subunit alpha-1C	0	11	0	11
Sodium channel protein type 5 subunit alpha	0	4	0	4
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	4	0	4
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Adenylyl cyclase 7	0	1	0	1
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	4	0	4
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Genome polyprotein	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Albumin	0	1	0	2
Cholinesterase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	7
Prostaglandin G/H synthase 1	0	2	0	2
Caspase-1	0	4	0	5
Prostaglandin G/H synthase 2	0	4	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
Aldo-keto reductase family 1 member C3	0	4	0	4
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Caspase-4	0	2	0	2
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Fatty-acid amide hydrolase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	3
Prostaglandin G/H synthase 1	0	4	0	6
Dehydrogenase/reductase SDR family member 9	0	1	0	1
DNA polymerase III, partial	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
Single-stranded DNA cytosine deaminase	2	0	0	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase IMP-1	0	0	0	2
Beta-lactamase	0	0	0	2
Leukotriene C4 synthase	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	3	3
Serine/threonine-protein kinase 25	0	0	3	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	3	3
Serine/threonine-protein kinase RIO3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 7	0	1	3	4
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	3	4
Peripheral plasma membrane protein CASK	0	0	3	3
Serine/threonine-protein kinase DCLK1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	3	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	3	3
3-phosphoinositide-dependent protein kinase 1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 13	0	0	3	3
Death-associated protein kinase 3	0	0	3	3
NUAK family SNF1-like kinase 1	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	3	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	3	3
Serine/threonine-protein kinase PAK 3	0	0	3	3
Serine/threonine-protein kinase 17B	0	0	3	3
Cyclin-dependent kinase 14	0	0	3	3
Serine/threonine-protein kinase OSR1	0	0	3	3
Serine/threonine-protein kinase Chk2	0	0	3	3
Receptor tyrosine-protein kinase erbB-2	0	3	4	7
Macrophage colony-stimulating factor 1 receptor	0	2	3	5
Proto-oncogene tyrosine-protein kinase ROS	0	1	3	4
Wee1-like protein kinase 2	0	0	3	3
Uncharacterized serine/threonine-protein kinase SBK3	0	0	3	3
Insulin receptor-related protein	0	0	3	3
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	3	3
Serine/threonine-protein kinase MAK	0	0	3	3
Cyclin-dependent kinase 11B	0	0	3	3
Fibroblast growth factor receptor 2	0	1	3	4
Receptor tyrosine-protein kinase erbB-3	0	1	3	4
Fibroblast growth factor receptor 4	0	0	3	3
Fibroblast growth factor receptor 3	0	0	3	3
Protein kinase C eta type	0	0	4	4
Activin receptor type-2A	0	0	3	3
Ephrin type-A receptor 3	0	0	3	3
Ephrin type-A receptor 8	0	0	3	3
Leukocyte tyrosine kinase receptor	0	0	3	3
Mitogen-activated protein kinase 4	0	0	3	3
G protein-coupled receptor kinase 4	0	0	3	3
Tyrosine-protein kinase receptor Tie-1	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	3	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	3	3
Serine/threonine-protein kinase mTOR	0	2	4	6
Megakaryocyte-associated tyrosine-protein kinase	0	0	3	3
Tyrosine-protein kinase TXK	0	2	4	6
Tyrosine-protein kinase ZAP-70	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	0	3	3
Cyclin-dependent kinase 8	0	0	3	3
Tyrosine-protein kinase Blk	0	2	4	6
Cytoplasmic tyrosine-protein kinase BMX	0	3	4	7
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	4	4
Serine/threonine-protein kinase Nek4	0	0	3	3
Death-associated protein kinase 1	0	0	3	3
Ephrin type-B receptor 1	0	0	3	3
Oxysterols receptor LXR-beta	0	1	0	1
Hormonally up-regulated neu tumor-associated kinase	0	0	3	3
Serine/threonine-protein kinase SIK1	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 4	0	0	3	3
Cell division control protein 2 homolog	0	0	3	3
Calcium-dependent protein kinase 1	0	0	3	3
Casein kinase II subunit alpha	0	1	3	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	3	3
SRSF protein kinase 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 9	0	0	3	3
Serine/threonine-protein kinase PknB	0	0	3	3
Cyclin-dependent kinase-like 1	0	0	3	3
Protein kinase C epsilon type	0	1	4	5
Mitogen-activated protein kinase kinase kinase 10	0	0	3	3
Tyrosine-protein kinase receptor TYRO3	0	0	3	3
Cyclin-dependent kinase 18	0	0	5	5
Tyrosine-protein kinase ITK/TSK	0	2	4	6
Myotonin-protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 12	0	0	3	3
Serine/threonine-protein kinase PAK 1	0	0	3	3
cGMP-dependent protein kinase 2	0	0	3	3
Serine/threonine-protein kinase PRP4 homolog	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1	0	0	3	3
Serine/threonine-protein kinase D1	0	0	4	4
Serine/threonine-protein kinase 38	0	0	4	4
Receptor tyrosine-protein kinase erbB-4	0	2	4	6
Ribosomal protein S6 kinase alpha-2	0	0	3	3
Rhodopsin kinase GRK1	0	0	3	3
NT-3 growth factor receptor	0	0	3	3
BDNF/NT-3 growth factors receptor	0	0	3	3
Mitogen-activated protein kinase 6	0	0	3	3
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	3	3
Serine/threonine-protein kinase SBK1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 19	0	0	3	3
Serine/threonine-protein kinase TNNI3K	0	0	3	3
Tyrosine-protein kinase JAK2	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	3	3
Mitogen-activated protein kinase kinase kinase 15	0	0	3	3
Serine/threonine-protein kinase tousled-like 2	0	0	3	3
Serine/threonine-protein kinase 32C	0	0	3	3
Serine/threonine-protein kinase pim-3	0	0	3	3
Serine/threonine-protein kinase VRK2	0	0	3	3
Myosin light chain kinase family member 4	0	0	3	3
Homeodomain-interacting protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1D	0	0	3	3
Cyclin-dependent kinase-like 3	0	0	3	3
Serine/threonine-protein kinase BRSK2	0	0	3	3
Serine/threonine-protein kinase NIM1	0	0	3	3
Serine/threonine-protein kinase ULK2	0	0	3	3
Serine/threonine-protein kinase DCLK2	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	3	3
Casein kinase I isoform alpha-like	0	0	3	3
Homeodomain-interacting protein kinase 4	0	0	3	3
Myosin-IIIa	0	0	3	3
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	3	3
Serine/threonine-protein kinase Nek11	0	0	3	3
Serine/threonine-protein kinase BRSK1	0	0	3	3
Serine/threonine-protein kinase 35	0	0	3	3
Rhodopsin kinase GRK7	0	0	3	3
Serine/threonine-protein kinase 32A	0	0	3	3
Myosin-IIIb	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	3	3
Cyclin-dependent kinase-like 2	0	0	3	3
Serine/threonine-protein kinase Sgk3	0	0	3	3
Atypical kinase COQ8B, mitochondrial	0	0	3	3
Cyclin-dependent kinase 15	0	0	3	3
SRSF protein kinase 1	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	3	3
Serine/threonine-protein kinase RIO1	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO2	0	0	3	3
Cyclin-dependent kinase 19	0	0	3	3
Transient receptor potential cation channel subfamily M member 6	0	0	3	3
Testis-specific serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase 33	0	0	3	3
Serine/threonine-protein kinase DCLK3	0	0	3	3
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	3	3
Homeodomain-interacting protein kinase 2	0	0	3	3
Tyrosine-protein kinase Srms	0	0	3	3
Homeodomain-interacting protein kinase 3	0	0	3	3
Serine/threonine-protein kinase PLK3	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	3	3
Serine/threonine-protein kinase Nek6	0	0	3	3
SNF-related serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase LATS2	0	0	3	3
Serine/threonine-protein kinase 36	0	0	3	3
Serine/threonine-protein kinase 32B	0	0	3	3
Serine/threonine-protein kinase PLK2	0	0	3	3
Serine/threonine-protein kinase MARK1	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	0	3	3
eIF-2-alpha kinase GCN2	0	0	3	3
Serine/threonine-protein kinase 17A	0	0	3	3
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	3	3
Ephrin type-A receptor 6	0	0	3	3
Death-associated protein kinase 2	0	0	3	3
Serine/threonine-protein kinase tousled-like 1	0	0	3	3
SRSF protein kinase 3	0	0	3	3
Cyclin-dependent kinase 11A	0	0	3	3
Aurora kinase C	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	3	3
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	6	0	6
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Thromboxane-A synthase	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	4	7
Sodium- and chloride-dependent betaine transporter	0	2	0	2
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2C8	0	3	0	4
Cytochrome P450 2A6	0	2	0	2
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Endonuclease 8-like 1	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Hsf1 protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
matrix metalloproteinase 1, partial	0	0	1	1
pyruvate kinase	2	0	0	2
histone deacetylase 9 isoform 3	4	0	0	4
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] A	0	4	0	4
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	1	0	2
Cereblon isoform 4	0	4	0	4
Bromodomain-containing protein 4	0	1	0	2
DNA-binding protein Ikaros	0	0	2	7
DNA damage-binding protein 1	0	3	2	5
Protein cereblon	0	6	3	15
Zinc finger protein Aiolos	0	0	2	2
CAAX prenyl protease 2 isoform 2	0	0	0	1
DNA primase	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Methionine aminopeptidase	0	1	0	1
Calmodulin-domain protein kinase 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Dipeptidyl peptidase 4	0	4	0	4
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
dopamine D1 receptor	4	0	0	4
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	2	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	4
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	3	0	3
Thymidylate synthase	0	5	0	5
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	5	0	5
Folate receptor beta	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	3	0	3
Bifunctional purine biosynthesis protein ATIC	0	5	0	5
Pteridine reductase 1	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	4	0	5
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	2	0	2
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	3	0	4
ATP-binding cassette sub-family C member 11	0	0	0	1
Multidrug resistance associated protein	0	1	0	2
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	2	0	0	2
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Cruzipain	0	1	0	1
Alpha-synuclein	3	2	0	5
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	2	0	0	2
Serine racemase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
WRN	1	0	0	1
LANA	0	0	0	1
phospholipase A2, group III	0	1	0	1
interferon gamma precursor	0	0	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	2
Casein kinase II subunit beta	0	1	0	1
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
P2Y purinoceptor 12	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Nuclear receptor corepressor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
ubiquitin-like modifier-activating enzyme 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
ubiquitin-conjugating enzyme E2 variant 1 isoform a	0	1	0	1
Complement C1r subcomponent	0	1	0	1
Coagulation factor X	0	1	0	1
Plasminogen	0	5	1	7
Coagulation factor XII	0	1	0	1
Cationic trypsin	0	1	0	1
Interstitial collagenase	0	2	0	2
Serine protease hepsin	0	2	0	2
Cathepsin D	0	1	0	1
Trypsin-1	0	3	0	3
Complement C1s subcomponent	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Hepatocyte growth factor activator	0	2	1	3
Suppressor of tumorigenicity 14 protein	0	1	0	1
Hormone-sensitive lipase	0	1	0	1
Atrial natriuretic peptide receptor 1	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Sialidase	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
MecA	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
bcl-2-related protein A1	0	2	0	2
P2X purinoceptor 4	0	1	0	1
Myosin light chain kinase, smooth muscle	0	0	2	2
Tubulin alpha-1A chain	0	0	2	2
Receptor protein-tyrosine kinase	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Putative nucleoside diphosphate kinase	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
G1/S-specific cyclin-E1	0	1	0	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Peroxiredoxin-like 2A	0	1	0	1
Platelet glycoprotein VI	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Serine hydroxymethyltransferase, cytosolic	0	1	1	2
Thymidylate synthase	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Beta-lactamase	0	0	0	1
Programmed cell death protein 1	0	1	0	1
E3 ubiquitin-protein ligase ZFP91	0	0	0	1
Programmed cell death 1 ligand 1	0	1	0	1
Sterol 14-alpha-demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
Amine oxidase [flavin-containing] B	0	3	0	3
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Trace amine-associated receptor 5	0	0	3	3
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
dual specificity protein phosphatase 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Estrogen receptor	0	0	2	2
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Estrogen receptor beta	0	0	2	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
NS5	0	1	1	2
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Cytochrome P450 3A5	0	1	1	2
Amine oxidase [flavin-containing] A	0	1	0	1
Catechol O-methyltransferase	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
C-C chemokine receptor type 2	0	1	0	1
Cannabinoid receptor 2	0	0	1	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	2	1	3
Glutamate receptor ionotropic, NMDA 1	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	2	1	3
ATP-binding cassette sub-family C member 8	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	1
Glutamate receptor ionotropic, NMDA 2B	0	0	1	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	1	1
Thrombin	0	0	1	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	1
Estrogen receptor beta	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Chymotrypsin-like elastase family member 1	0	1	0	1
Kallikrein-1	0	1	0	1
Trypsin-2	0	1	0	1
Cathepsin G	0	1	0	1
Chymotrypsin-like elastase family member 2A	0	1	0	1
Myeloblastin	0	1	0	1
Trypsin-3	0	1	0	1
Neutrophil elastase	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Chain A, Glutathione S-transferase	0	1	0	1
Tumor necrosis factor	0	0	1	1
Fibroblast growth factor 1	0	0	1	1
Flavin reductase (NADPH)	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
B2 bradykinin receptor	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase L1 type 3	0	1	0	1
Beta-lactamase	0	1	0	1
NS3 protease	0	2	0	3
Cathepsin L2	0	1	0	1
Cathepsin B	0	1	0	1
Chymase	0	1	0	1
Cathepsin S	0	1	0	2
Cathepsin K	0	1	0	1
NS3 protease	0	1	0	1
Cathepsin F	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Cytochrome P450 2B1	0	1	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase JAK2	0	1	0	1
Serine/threonine-protein kinase Sgk1	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Erythrophagocytic Lymphohistiocytosis, Familial

Synonyms(19)

Research Excerpts

Overview

Treatment

Research

Studies (836)

Protein Targets (2,018)

Erythrophagocytic Lymphohistiocytosis, Familial

Synonyms(19)

Research Excerpts

Overview

Treatment

Research

Studies (836)

Drugs Studied (253)

Protein Targets (2,018)