Enterotoxemia

Disease caused by the liberation of exotoxins of CLOSTRIDIUM PERFRINGENS in the intestines of sheep, goats, cattle, foals, and piglets. Type B enterotoxemia in lambs is lamb dysentery; type C enterotoxemia in mature sheep produces struck, and in calves, lambs and piglets it produces hemorrhagic enterotoxemia; type D enterotoxemia in sheep and goats is pulpy-kidney disease or overeating disease.

Synonym
Enterotoxemia

Excerpt	Reference
"Sheep pox and enterotoxemia are important diseases of sheep, and these diseases cause severe economic losses to sheep farmers."	( Chandran, D; Garg, LC; Mathur, D; Naidu, SS; Rani, GS; Srinivasan, VA; Sugumar, P; Vijayan, SP, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	28 (68.29)	23.3326
1990's	3 (7.32)	12.5806
2000's	4 (9.76)	18.1394
2010's	5 (12.20)	28.8240
2020's	1 (2.44)	9.53

Drug	Relationship Strength	Studies
quinacrine	low	1
chlorine	low	1
hydrochloric acid	low	1
formaldehyde	low	2
1-anilino-8-naphthalenesulfonate	low	1
verapamil	low	1
furazolidone	low	1
patulin	low	1
sulfamethazine	low	1
chloroform	low	1
ampicillin	low	1
quinoxalines	low	1
framycetin	low	1
evans blue	low	1
aluminum sulfate	low	1
trolamine salicylate	low	1
glutamic acid	low	1
avilamycin	low	1
nsc-172755	low	1
fibrinogen	low	2
foxes	low	1
cortisone	low	1
clindamycin phosphate	low	1
clindamycin	low	3
taprostene	low	1
sulfur	low	3
nitrofurazone	low	1
phosphorus	low	1
tylosin	low	1
chlortetracycline	low	2
rifampin	low	1
cholestyramine resin	low	1

Protein Targets (503)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	2	0	0	2
thioredoxin reductase	7	0	0	7
USP1 protein, partial	3	0	0	3
TDP1 protein	10	0	0	10
vitamin D3 receptor isoform VDRA	2	0	0	2
importin subunit beta-1 isoform 1	2	0	0	2
flap endonuclease 1	3	0	0	3
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	3	0	0	3
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
geminin	5	0	0	5
DNA polymerase kappa isoform 1	4	0	0	4
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	0	1	1
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	1	1	2
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	4	0	0	4
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Cruzipain	2	0	0	2
Beta-lactamase	0	0	0	1
GLS protein	3	0	0	3
GLI family zinc finger 3	6	0	0	6
apical membrane antigen 1, AMA1	1	0	0	1
retinoic acid nuclear receptor alpha variant 1	5	0	0	5
farnesoid X nuclear receptor	4	0	0	4
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
euchromatic histone-lysine N-methyltransferase 2	8	0	0	8
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
chromobox protein homolog 1	5	0	0	5
thyroid hormone receptor beta isoform 2	7	0	0	7
DNA polymerase beta	1	0	0	1
Carbonic anhydrase 1	0	3	0	4
Carbonic anhydrase 2	0	3	0	4
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	3	0	0	3
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	3	0	3
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	3	0	3
Metallo-b-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
ATP-dependent phosphofructokinase	1	0	0	1
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 15	0	1	0	1
Luciferase	1	0	0	1
interleukin 8	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	2	0	0	2
RAR-related orphan receptor gamma	5	0	0	5
nuclear receptor subfamily 1, group I, member 3	6	0	0	6
progesterone receptor	4	0	0	4
retinoid X nuclear receptor alpha	7	0	0	7
estrogen-related nuclear receptor alpha	4	0	0	4
estrogen nuclear receptor alpha	12	0	0	12
peroxisome proliferator-activated receptor delta	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
Histone H2A.x	2	0	0	2
lamin isoform A-delta10	3	0	0	3
Voltage-dependent calcium channel gamma-2 subunit	4	0	0	4
Cellular tumor antigen p53	3	0	0	3
Glutamate receptor 2	4	2	1	7
Nuclear receptor ROR-gamma	2	0	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein-arginine deiminase type-4	0	3	0	3
Serum paraoxonase/arylesterase 1	0	1	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
endonuclease IV	1	0	0	1
dopamine D1 receptor	2	0	0	2
pregnane X receptor	1	0	0	1
AR protein	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
regulator of G-protein signaling 4	5	0	0	5
glucocorticoid receptor [Homo sapiens]	6	0	0	6
pregnane X nuclear receptor	5	0	0	5
peroxisome proliferator activated receptor gamma	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
peripheral myelin protein 22 isoform 1	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
heat shock protein beta-1	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	5	0	0	5
survival motor neuron protein isoform d	4	0	0	4
cytochrome P450 3A4 isoform 1	3	0	0	3
M-phase phosphoprotein 8	2	0	0	2
muscarinic acetylcholine receptor M1	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	3	0	0	3
Bile salt export pump	0	6	0	6
Glucocorticoid receptor	0	2	0	2
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	3	0	0	3
Gamma-aminobutyric acid receptor subunit delta	3	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	3	0	0	3
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	3	0	0	3
Glycine receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	3	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	3	0	0	3
Gamma-aminobutyric acid receptor subunit beta-3	3	0	0	3
Gamma-aminobutyric acid receptor subunit beta-2	3	0	0	3
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	1	0	0	1
GABA theta subunit	3	0	0	3
Multidrug and toxin extrusion protein 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	3	0	0	3
phosphopantetheinyl transferase	2	0	0	2
ATAD5 protein, partial	2	0	0	2
Fumarate hydratase	3	0	0	3
PPM1D protein	1	0	0	1
thyroid stimulating hormone receptor	2	0	0	2
EWS/FLI fusion protein	2	0	0	2
cytochrome P450 2D6	2	0	0	2
polyprotein	3	0	0	3
cytochrome P450 2D6 isoform 1	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
cytochrome P450 2C19 precursor	1	0	0	1
D(1A) dopamine receptor	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
huntingtin isoform 2	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
peripheral myelin protein 22	2	0	0	2
histone acetyltransferase KAT2A isoform 1	3	0	0	3
lethal factor (plasmid)	1	0	0	1
chaperonin GroEL	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	4	0	4
Interferon beta	3	0	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
Muscarinic acetylcholine receptor M2	0	4	0	4
Muscarinic acetylcholine receptor M4	0	4	0	4
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M5	0	4	0	4
Alpha-2A adrenergic receptor	0	6	0	6
Muscarinic acetylcholine receptor M2	0	2	0	2
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	0	4
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-2B adrenergic receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	4	0	4
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	4	0	4
Muscarinic acetylcholine receptor M3	0	4	0	4
Endothelin receptor type B	0	1	0	1
D(1A) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Sodium-dependent noradrenaline transporter	0	4	0	4
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	6	0	6
Alpha-1D adrenergic receptor	0	4	0	4
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	6	0	6
5-hydroxytryptamine receptor 2C	0	4	0	4
5-hydroxytryptamine receptor 1B	0	4	0	4
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	2	1	3
D(3) dopamine receptor	0	6	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Histamine H2 receptor	2	0	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	3	0	3
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Ataxin-2	4	0	0	4
Transporter	0	1	0	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	2	0	0	2
Albumin	0	0	3	3
Luciferin 4-monooxygenase	0	1	0	1
60 kDa chaperonin	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	0	0	1
Tyrosine-protein phosphatase 1	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Vesicular glutamate transporter 3	0	1	0	1
ATPase family AAA domain-containing protein 5	1	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
glp-1 receptor, partial	2	0	0	2
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	3
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Integrin beta-3	2	0	1	3
Integrin alpha-IIb	2	0	1	3
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	2
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	3
Glutamate receptor ionotropic, NMDA 2B	0	2	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	1	3
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	1	3
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	1	3
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	1	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
acetylcholinesterase	2	0	0	2
thioredoxin glutathione reductase	2	0	0	2
Smad3	2	0	0	2
estrogen receptor 2 (ER beta)	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	2	0	0	2
G	2	0	0	2
aryl hydrocarbon receptor	2	0	0	2
thyroid stimulating hormone receptor	2	0	0	2
thyroid hormone receptor beta isoform a	2	0	0	2
transcriptional regulator ERG isoform 3	1	0	0	1
nuclear receptor ROR-gamma isoform 1	2	0	0	2
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Snake venom metalloproteinase BaP1	0	1	0	1
NAD(+) hydrolase SARM1	0	2	0	2
Inositol hexakisphosphate kinase 1	2	0	0	2
cytochrome P450 2C9, partial	2	0	0	2
Genome polyprotein	0	1	0	1
Microtubule-associated protein tau	2	0	0	2
67.9K protein	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
mitogen-activated protein kinase 1	1	0	0	1
N	0	1	0	1
NPYLR7B	0	0	1	1
arylsulfatase A	1	0	0	1
IDH1	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
tumor susceptibility gene 101 protein	1	0	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	0	1	1
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
ATP-dependent translocase ABCB1	0	2	2	11
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Trypanothione reductase	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
Aldehyde oxidase 1	0	1	0	1
Cholinesterase	0	1	0	1
Aldehyde oxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
15-lipoxygenase, partial	1	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
ATP-binding cassette sub-family C member 3	0	2	0	2
Multidrug resistance-associated protein 4	0	2	0	2
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Bile salt export pump	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Cytochrome P450 2B6	0	0	1	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Alpha-synuclein	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	2
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	1	3
Solute carrier organic anion transporter family member 1B1	0	4	0	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
glucocerebrosidase	1	0	0	1
activating transcription factor 6	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Solute carrier family 22 member 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Cytochrome P450 3A4	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2C9	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	2
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Multidrug resistance-associated protein 1	0	2	1	4
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (41)

Protein Targets (503)

Enterotoxemia

Synonyms(1)

Research Excerpts

Overview

Research

Studies (41)

Drugs Studied (39)

Protein Targets (503)