Roles > cardiotoxic agent
Page last updated: 2024-08-05 15:37:54
cardiotoxic agent
A role played by a chemical compound exihibiting itself through the ability to induce damage to the heart and cardiomyocytes.
ChEBI ID: 50912
Members (5)
| Member | Definition | Class |
|---|
| adriamycinol | A member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties. | doxorubicinol |
| fluoroacetaldehyde | An aldehyde that is acetaldehyde in which one of the hydrogens of the methyl group is replaced by fluorine. | fluoroacetaldehyde |
| ponceau mx | A naphthalenesulfonic acid that is naphthalene-2,7-disulfonic acid carrying additional hydroxy and (2,4-dimethylphenyl)diazenyl substituents at positions 3 and 4 respectively. The disodium salt is the biological stain 'acid red 26'. | 4-[(2,4-dimethylphenyl)diazenyl]-3-hydroxynaphthalene-2,7-disulfonic acid |
| t-2 toxin | A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals. | T-2 toxin |
| tilmicosin | A macrolide antibiotic with formula C46H80N2O13. It is used for the treatment of respiratory disease in cattle at high risk of developing bovine respiratory disease associated with Mannheimia haemolytica. | tilmicosin |
Research
Studies (189)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 60 (31.75) | 18.7374 |
| 1990's | 41 (21.69) | 18.2507 |
| 2000's | 42 (22.22) | 29.6817 |
| 2010's | 36 (19.05) | 24.3611 |
| 2020's | 10 (5.29) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 11 (5.42%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 4 (1.97%) | 4.05% |
| Observational | 1 (0.49%) | 0.25% |
| Other | 187 (92.12%) | 84.16% |
Protein Targets (5)
Potency Measurements