null
ChEBI ID: 39277
| Member | Definition | Class |
|---|---|---|
| chloropicrin | A C-nitro compound that is nitromethane in which all three hydrogens are replaced by chlorines. It is a severe irritant, and can cause immediate, severe inflammation of the eyes, nose and throat, and significant injuries to the upper and lower respiratory tract. Formerly stockpiled as a chemical warfare agent, it has been widely used in the US as a soil fumigant, particularly for strawberry crops. It is not approved for use within the European Union. | chloropicrin |
| methyl bromide | A one-carbon compound in which the carbon is attached by single bonds to three hydrogen atoms and one bromine atom. It is produced naturally by marine algae. | bromomethane |
| methyl iodide | A member of the class of iodomethanes that is methane in which one of the hydrogens is replaced by iodine. | iodomethane |
| phosphine | The simplest phosphine, consisting of a single phosphorus atom with three hydrogens attached. | phosphane |
| sulfuryl fluoride | sulfuryl difluoride |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 300 (13.06) | 18.7374 |
| 1990's | 180 (7.84) | 18.2507 |
| 2000's | 573 (24.95) | 29.6817 |
| 2010's | 942 (41.01) | 24.3611 |
| 2020's | 302 (13.15) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (0.04%) | 5.53% |
| Reviews | 108 (4.37%) | 6.00% |
| Case Studies | 108 (4.37%) | 4.05% |
| Observational | 1 (0.04%) | 0.25% |
| Other | 2,252 (91.17%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 13.6437 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 13.6437 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 54.7663 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 0.1718 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 10.8376 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 3.0205 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 43.5024 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 1.5849 | 2 | 2 |