| Assay ID | Title | Year | Journal | Article |
|---|
| AID164993 | Inhibition of human Protein-tyrosine phosphatase 1B | 2003 | Bioorganic & medicinal chemistry letters, Aug-04, Volume: 13, Issue:15
| Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors. |
| AID551666 | Inhibition of human recombinant MAOB expressed in baculovirus-infected BTI insect cells after 15 mins by fluorimetric assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 21, Issue:2
| Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors. |
| AID478549 | Selectivity index, ratio of IC50 for human recombinant MAO-A to IC 50 for human recombinant MAO-B | 2010 | Bioorganic & medicinal chemistry letters, May-01, Volume: 20, Issue:9
| Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B. |
| AID1133474 | Antianaphylactic activity in rat mast cells assessed as inhibition of DNP-ovalbumin-induced histamine release after 15 mins by superfusion assay | 1978 | Journal of medicinal chemistry, Nov, Volume: 21, Issue:11
| Benzopyrones. 14. Synthesis and antiallergic properties of some N-tetrazolylcarboxamides and related compounds. |
| AID1145601 | Dissociation constant, pKa of the compound | 1977 | Journal of medicinal chemistry, Jan, Volume: 20, Issue:1
| Studies on antianaphylactic agents. 5. Synthesis of 3-(1H-tetrazol-5-yl)chromones, a new series of antiallergic substances. |
| AID478545 | Inhibition of human recombinant MAO-A assessed as inhibition of production of hydrogen peroxide at 100 uM after 15 mins by the Amplex Red fluorimetric method | 2010 | Bioorganic & medicinal chemistry letters, May-01, Volume: 20, Issue:9
| Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B. |
| AID1133475 | Antianaphylactic activity in rat mast cells assessed as inhibition of DNP-ovalbumin-induced histamine release after 15 mins by superfusion assay relative to 4-oxo-N-(5-tetrazolyl)-4H-l-benzopyran-2-carboxamide | 1978 | Journal of medicinal chemistry, Nov, Volume: 21, Issue:11
| Benzopyrones. 14. Synthesis and antiallergic properties of some N-tetrazolylcarboxamides and related compounds. |
| AID365671 | pKa of the compound | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16
| Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: synthesis, SAR, and in-vitro assessment. |
| AID551669 | Selectivity ratio of IC50 for human recombinant MAOA to IC50 for human recombinant MAOB | 2011 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 21, Issue:2
| Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors. |
| AID1133476 | Antiallergic activity in rat assessed as inhibition of DNP-ovalbumin-induced passive cutaneous anaphylaxis at 1 mg/kg, iv after 30 mins relative to control | 1978 | Journal of medicinal chemistry, Nov, Volume: 21, Issue:11
| Benzopyrones. 14. Synthesis and antiallergic properties of some N-tetrazolylcarboxamides and related compounds. |
| AID478547 | Inhibition of human recombinant MAO-B assessed as inhibition of production of hydrogen peroxide after 15 mins by the Amplex Red fluorimetric method | 2010 | Bioorganic & medicinal chemistry letters, May-01, Volume: 20, Issue:9
| Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |