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ChEBI ID: 46756
| Member | Definition | Role |
|---|---|---|
| hepes | A HEPES that is ethanesulfonic acid in which one of the methyl hydrogens is replaced by a 4-(2-hydroxyethyl)piperazin-1-yl group. A Good's buffer substance, pKa = 7.55 at 20 degreeC. | 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; 2-[4-(2-hydroxyethyl)piperazin-4-ium-1-yl]ethanesulfonate |
| hepes | A HEPES that is ethanesulfonate substituted by a 4-(2-hydroxyethyl)piperazin-4-ium-1-yl group at position 2. | 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; 2-[4-(2-hydroxyethyl)piperazin-4-ium-1-yl]ethanesulfonate |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 155 (23.34) | 18.7374 |
| 1990's | 178 (26.81) | 18.2507 |
| 2000's | 184 (27.71) | 29.6817 |
| 2010's | 106 (15.96) | 24.3611 |
| 2020's | 41 (6.17) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 11 (1.56%) | 5.53% |
| Reviews | 3 (0.43%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 690 (98.01%) | 84.16% |