Page last updated: 2024-09-28

Frontal Sinusitis

Inflammation of the NASAL MUCOSA in the FRONTAL SINUS. In many cases, it is caused by an infection of the bacteria STREPTOCOCCUS PNEUMONIAE or HAEMOPHILUS INFLUENZAE.

Synonyms(2)

Synonym
Frontal Sinusitis
Sinusitis, Frontal

Research Excerpts

Overview

ExcerptReference
"Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow-up period."( Hirakawa, K; Ishino, T; Kubota, K; Sasaki, A; Takeno, S; Taruya, T, 2017)

Treatment

ExcerptReference
"Persistent frontal sinusitis traditionally has been treated with external procedures such as osteoplastic frontal sinus obliteration or the Lynch procedure."( Becker, D; Gross, CW; Gross, WE; Moore, D; Phillips, D, 1995)
"Acute frontal sinusitis was treated by therapeutic complex incorporating drainage of the frontal sinus, its lavage with antiseptic solution, mechanical low-frequency biovibromassage."( Logunov, AI; Tsyrul'nikova, LG; Zelenkin, EM, 1998)
"102 patients with chronic purulent frontal sinusitis received treatment consisting in irrigation of the paranasal sinuses with ozone-oxygen mixture."( Khushvakova, NZh; Muminov, AI, 2002)
"Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow-up period."( Hirakawa, K; Ishino, T; Kubota, K; Sasaki, A; Takeno, S; Taruya, T, 2017)

Research

Studies (84)

TimeframeStudies, This Condition (%)All Conditions %
pre-19906 (7.14)23.3326
1990's21 (25.00)12.5806
2000's29 (34.52)18.1394
2010's26 (30.95)28.8240
2020's2 (2.38)9.53
DrugIndicatedRelationship StrengthStudiesTrials
1-butanol0low10
citric acid, anhydrous0low10
salicylic acid0low40
cefuroxime0low10
ciprofloxacin0medium11
clotrimazole0low10
guaifenesin0low20
ibuprofen0low10
ketoconazole0low10
lithium hydroxide0low10
metronidazole0low30
phenobarbital0low10
sulfanilamide0low10
trimethoprim0medium11
mitomycin0medium21
prednisone0low10
penicillin g0low10
chloramphenicol0low10
gliotoxin0low10
ampicillin0low10
tromethamine0low10
methylmethacrylate0low10
boric acid0low10
betamethasone0low10
fusarium0medium11
methamphetamine0low10
acetylcysteine0medium11
durapatite0low20
vancomycin0low20
titanium0low10
gadolinium0low20
tricalcium phosphate0low10
ozone0low10
transferrin0low10
amoxicillin0medium51
enilconazole0low10
propiconazole0low160
itraconazole0low10
betamethasone sodium phosphate0low10
cephalosporin c0low10
brodimoprim0medium11
technetium tc 99m hydroxymethylene diphosphonate0low10
sulbactam0low10
moxifloxacin0low20
meropenem0low10
sultamicillin0low10
clindamycin0low10
zithromax0medium11
sodium benzoate0low10
fusafungin0medium11
amphotericin b0low20
clavulanic acid0low20
phenylephrine hydrochloride0low90
silicon0low10
cefotaxime0low10
amoxicillin-potassium clavulanate combination0medium41
mocetinostat0low10
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one0medium11
ro13-99040low30
interleukin-80medium11
transforming growth factor beta0low10
technetium tc 99m medronate0low20
eye0low10

Protein Targets (842)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
IDH1100010
chromobox protein homolog 1100010
geminin170017
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
aldehyde dehydrogenase 1 family, member A1110011
glucocorticoid receptor [Homo sapiens]200020
farnesoid X nuclear receptor160016
estrogen nuclear receptor alpha270027
Voltage-dependent calcium channel gamma-2 subunit9009
Cellular tumor antigen p53170017
Glutamate receptor 29009
Choline O-acetyltransferase 0102
Chain A, JmjC domain-containing histone demethylation protein 3A5005
Chain A, 2-oxoglutarate Oxygenase7007
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
acetylcholinesterase4004
dopamine D1 receptor2002
15-lipoxygenase, partial2002
pregnane X receptor6006
phosphopantetheinyl transferase4004
RAR-related orphan receptor gamma9009
USP1 protein, partial4004
NFKB1 protein, partial4004
Microtubule-associated protein tau3003
Thrombopoietin2002
AR protein210021
regulator of G-protein signaling 43003
retinoic acid nuclear receptor alpha variant 1140014
retinoid X nuclear receptor alpha140014
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
arylsulfatase A4004
euchromatic histone-lysine N-methyltransferase 2100010
Bloom syndrome protein isoform 15005
D(1A) dopamine receptor1001
thyroid hormone receptor beta isoform a7007
thyroid hormone receptor beta isoform 2150015
heat shock protein beta-15005
flap endonuclease 14004
peripheral myelin protein 225005
survival motor neuron protein isoform d3003
muscarinic acetylcholine receptor M16006
Histone deacetylase 30505
Solute carrier family 22 member 60606
Histone deacetylase 40404
Guanine nucleotide-binding protein G4004
Histone deacetylase 10505
Histone deacetylase 70404
Histone deacetylase 20505
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0404
Ataxin-25005
Histone deacetylase 80404
Histone deacetylase 60404
Histone deacetylase 90303
Histone deacetylase 50404
ATP-dependent phosphofructokinase4004
Chain A, Beta-lactamase4004
Beta-lactamase 0103
Beta-lactamase 0104
Beta-lactamase 0004
Beta-lactamase 0205
apical membrane antigen 1, AMA12002
Beta-lactamase 0003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)7007
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
DNA polymerase kappa isoform 15005
ATP-binding cassette sub-family C member 3015015
Multidrug resistance-associated protein 4015015
Bile salt export pump0606
Bile salt export pump026026
Beta-lactamase SHV-10104
Beta-lactamase SHV-10307
Cytochrome P450 2C9 08210
Beta-lactamase0206
Kappa-type opioid receptor0003
Solute carrier family 15 member 10505
Solute carrier family 15 member 10202
Cytochrome P450 2J20303
B2 metallo-beta-lactamase 0004
Solute carrier family 15 member 20404
Beta-lactamase 0104
Beta-lactamase 0104
Solute carrier family 15 member 20404
Beta-lactamase 0104
Beta-lactamase 0003
Canalicular multispecific organic anion transporter 1014014
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, Cruzipain3003
interleukin 85005
GLS protein6006
peroxisome proliferator-activated receptor delta9009
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA7007
nuclear factor erythroid 2-related factor 2 isoform 1160016
lamin isoform A-delta10120012
Cytochrome P450 1A20303
Cytochrome P450 3A4011013
Cytochrome P450 2D60404
Cytochrome P450 2C190505
Nuclear receptor ROR-gamma5005
Potassium voltage-gated channel subfamily H member 2012014
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Chain A, Mutant Al2 6e7p9g0011
Beta-lactamase 0003
acid sphingomyelinase1001
GLI family zinc finger 3160016
Beta-lactamase 0204
Beta-lactamase 0004
Metallo-beta-lactamase type 20015
Metallo-beta-lactamase VIM-11 0004
Metallo-beta-lactamase VIM-20004
Beta-lactamase 0105
Metallo-beta-lactamase0004
Beta-lactamase 0204
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
DNA polymerase beta1001
Carbonic anhydrase 10809
Carbonic anhydrase 209111
60 kDa heat shock protein, mitochondrial0202
Beta-lactamase OXA-70001
Spike glycoprotein8008
10 kDa heat shock protein, mitochondrial0202
Angiopoietin-1 receptor0011
Beta-lactamase 0204
Beta-lactamase 0204
Beta-lactamase 0204
Thiosulfate sulfurtransferase0202
Metallo-beta-lactamase VIM-130004
Efflux transporter 0002
Beta-lactamase 0003
Beta-lactamase Toho-10003
Beta-lactamase 0002
Class D beta-lactamase0204
60 kDa chaperonin 0202
Metallo-beta-lactamase0003
Beta-lactamase 0205
Beta-lactamase 0014
10 kDa chaperonin 0202
Metallo-b-lactamase 0006
Carbapenem-hydrolyzing beta-lactamase KPC0307
Histamine H3 receptor0003
Beta-lactamase class B VIM-2 0017
Beta-lactamase VIM-1 0004
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
thioredoxin reductase5005
thyroid stimulating hormone receptor8008
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 49009
EWS/FLI fusion protein100010
estrogen-related nuclear receptor alpha170017
cytochrome P450 2D68008
glucocerebrosidase1001
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
lethal factor (plasmid)4004
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0303
Prostaglandin G/H synthase 2 0303
Epidermal growth factor receptor0404
Fatty acid-binding protein, liver0202
Integrin beta-31102
Myeloperoxidase0101
Prostaglandin G/H synthase 10303
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb1102
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10404
Adenosine receptor A10202
Adenosine receptor A2a0202
Substance-P receptor0202
Prostaglandin G/H synthase 20606
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0202
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-16208
Prostaglandin G/H synthase 20303
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Sigma non-opioid intracellular receptor 10314
Sigma non-opioid intracellular receptor 10011
progesterone receptor9009
pregnane X nuclear receptor140014
aryl hydrocarbon receptor100010
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
nuclear receptor subfamily 1, group I, member 26006
nuclear factor erythroid 2-related factor 2 isoform 26006
galanin receptor type 30101
Glucocorticoid receptor0819
Glycine receptor subunit alpha-10808
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
ORF730011
peroxisome proliferator activated receptor gamma110011
Beta-lactamase0304
Beta-lactamase0606
Dihydrofolate reductase0303
Dihydrofolate reductase0303
Dihydrofolate reductase0404
Dihydrofolate reductase0304
Bifunctional dihydrofolate reductase-thymidylate synthase0203
Dihydrofolate reductase 0202
Dihydrofolate reductase0203
Mu-type opioid receptor0606
Delta-type opioid receptor0707
Kappa-type opioid receptor0516
Beta-lactamase 0204
Beta-lactamase 0204
Metallo-beta-lactamase VIM-19 0003
Beta-lactamase 0204
Albumin0235
Beta-lactamase 0002
Beta-lactamase 0204
Metallo-beta-lactamase VIM-20003
Solute carrier family 22 member 60303
Solute carrier family 22 member 70102
BlaVIM-1 0003
Beta-lactamase 0002
Solute carrier family 22 member 80404
Beta-lactamase 0104
Solute carrier family 22 member 110101
Solute carrier family 22 member 80203
Solute carrier family 22 member 70101
TDP1 protein130013
G7007
activating transcription factor 65005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
streptokinase A precursor0055
Dihydroxyacetone phosphate acyltransferase0001
Interferon beta8008
HLA class I histocompatibility antigen, B alpha chain 7007
30S ribosomal protein S60202
30S ribosomal protein S70202
50S ribosomal protein L150202
50S ribosomal protein L100202
50S ribosomal protein L110202
50S ribosomal protein L7/L120202
50S ribosomal protein L190202
50S ribosomal protein L10202
50S ribosomal protein L200202
50S ribosomal protein L270202
50S ribosomal protein L280202
50S ribosomal protein L290202
50S ribosomal protein L310202
50S ribosomal protein L31 type B0202
50S ribosomal protein L320202
50S ribosomal protein L330202
50S ribosomal protein L340202
50S ribosomal protein L350202
50S ribosomal protein L360202
30S ribosomal protein S100202
30S ribosomal protein S110202
30S ribosomal protein S120202
30S ribosomal protein S130202
30S ribosomal protein S160202
30S ribosomal protein S180202
30S ribosomal protein S190202
30S ribosomal protein S200202
30S ribosomal protein S20202
30S ribosomal protein S30202
30S ribosomal protein S40202
30S ribosomal protein S50202
30S ribosomal protein S80202
30S ribosomal protein S90202
50S ribosomal protein L130202
50S ribosomal protein L140202
50S ribosomal protein L160202
50S ribosomal protein L230202
30S ribosomal protein S150202
50S ribosomal protein L170202
50S ribosomal protein L210202
50S ribosomal protein L300202
50S ribosomal protein L60202
30S ribosomal protein S140202
30S ribosomal protein S170202
30S ribosomal protein S10202
50S ribosomal protein L180202
50S ribosomal protein L20202
50S ribosomal protein L30202
50S ribosomal protein L240202
50S ribosomal protein L40202
50S ribosomal protein L220202
50S ribosomal protein L50202
30S ribosomal protein S210202
50S ribosomal protein L250202
50S ribosomal protein L36 20202
Inositol hexakisphosphate kinase 17007
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial7007
cytochrome P450 2C9 precursor3003
Gamma-aminobutyric acid receptor subunit pi6107
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0203
DNA gyrase subunit A0205
DNA gyrase subunit B0205
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0203
DNA topoisomerase 2-alpha0105
Gamma-aminobutyric acid receptor subunit beta-16107
Gamma-aminobutyric acid receptor subunit delta6107
Gamma-aminobutyric acid receptor subunit gamma-26107
Gamma-aminobutyric acid receptor subunit alpha-56107
Gamma-aminobutyric acid receptor subunit alpha-36107
DNA gyrase subunit A0203
Gamma-aminobutyric acid receptor subunit gamma-16107
Gamma-aminobutyric acid receptor subunit alpha-26107
Gamma-aminobutyric acid receptor subunit alpha-46107
Gamma-aminobutyric acid receptor subunit gamma-36107
Gamma-aminobutyric acid receptor subunit alpha-66107
Multidrug resistance protein MdtK0011
Histamine H2 receptor4004
Gamma-aminobutyric acid receptor subunit beta-36107
Gamma-aminobutyric acid receptor subunit beta-26107
DNA gyrase subunit B0203
DNA gyrase subunit A0203
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0101
GABA theta subunit6107
Gamma-aminobutyric acid receptor subunit epsilon6107
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
nuclear receptor subfamily 1, group I, member 3110011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Beta-lactamase 0202
Beta-lactamase0204
Neutrophil elastase0101
Beta-lactamase OXA-10202
Cytochrome P450 2B60101
Beta-lactamase TEM0609
Beta-lactamase0101
Beta-lactamase 0101
Beta-lactamase 0101
Protein-arginine deiminase type-40303
Chain A, Ferritin light chain2002
Luciferase5005
endonuclease IV2002
glp-1 receptor, partial6006
hypoxia-inducible factor 1 alpha subunit5005
SMAD family member 25005
ATAD5 protein, partial2002
Fumarate hydratase4004
PPM1D protein5005
SMAD family member 35005
Smad32002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
estrogen receptor 2 (ER beta)8008
isocitrate dehydrogenase 1, partial1001
nonstructural protein 14004
polyprotein4004
bromodomain adjacent to zinc finger domain 2B3003
alpha-galactosidase1001
pyruvate kinase1001
heat shock protein 900011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
calcineurin A1, putative0011
thyroid stimulating hormone receptor4004
thyrotropin-releasing hormone receptor1001
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x4004
Caspase-71001
beta-2 adrenergic receptor1012
cytochrome P450 2D6 isoform 13003
peripheral myelin protein 22 isoform 11001
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C19 precursor3003
potassium voltage-gated channel subfamily H member 2 isoform d3003
caspase-31001
huntingtin isoform 21001
mitogen-activated protein kinase 13003
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
ras-related protein Rab-9A2002
heat shock protein HSP 90-alpha isoform 20003
nuclear receptor ROR-gamma isoform 16006
lethal(3)malignant brain tumor-like protein 1 isoform I1001
cytochrome P450 3A4 isoform 16006
M-phase phosphoprotein 81001
neuropeptide S receptor isoform A1001
Solute carrier family 22 member 1 0303
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Intermediate conductance calcium-activated potassium channel protein 40101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
5-hydroxytryptamine receptor 40404
Transient receptor potential cation channel subfamily M member 20101
Chymotrypsinogen A0303
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20202
Steroid 17-alpha-hydroxylase/17,20 lyase0404
Histidine-rich protein PFHRP-II0101
Estrogen receptor0011
Tyrosine-protein kinase Fyn0202
Heme oxygenase 1 0202
ATP-dependent translocase ABCB10606
Epoxide hydrolase 10003
Aldo-keto reductase family 1 member B10707
Muscarinic acetylcholine receptor M20606
Muscarinic acetylcholine receptor M40404
ATP-dependent translocase ABCB10606
Beta-1 adrenergic receptor0404
Alpha-2A adrenergic receptor0707
Adenosine receptor A30404
Muscarinic acetylcholine receptor M10404
Aromatase0404
Beta-3 adrenergic receptor0404
D(2) dopamine receptor0404
Androgen receptor0606
Alpha-1B adrenergic receptor0505
Alpha-2B adrenergic receptor0606
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
5-hydroxytryptamine receptor 1A0606
Muscarinic acetylcholine receptor M30404
ATP-dependent translocase ABCB10606
Substance-K receptor0606
D(1A) dopamine receptor0404
D(4) dopamine receptor0404
Potassium voltage-gated channel subfamily A member 30101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Acetylcholinesterase0505
Heme oxygenase 20202
Sodium-dependent noradrenaline transporter 0819
Thromboxane-A synthase 0303
Histamine H2 receptor0606
C-X-C chemokine receptor type 10101
Alpha-1D adrenergic receptor0404
Substance-P receptor0404
Platelet-activating factor receptor0202
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
5-hydroxytryptamine receptor 1B0505
Indoleamine 2,3-dioxygenase 10202
Adenosine receptor A2a0404
Vasopressin V2 receptor0101
Adenosine receptor A10404
Sodium-dependent serotonin transporter0819
Histamine H1 receptor0202
D(3) dopamine receptor0404
Alpha-synuclein2002
Malate dehydrogenase, cytoplasmic0303
5-hydroxytryptamine receptor 2B0404
Alpha-1A adrenergic receptor0505
5-hydroxytryptamine receptor 60404
C-C chemokine receptor type 40101
Transitional endoplasmic reticulum ATPase0101
Disintegrin and metalloproteinase domain-containing protein 172002
Cytochrome P450 1440033
Steroid C26-monooxygenase0033
Cytochrome P450 1300011
Cytochrome P450 1300011
Steroid C26-monooxygenase0033
Mycocyclosin synthase0022
Lanosterol 14-alpha demethylase0022
Sodium-dependent dopamine transporter 0808
TAR DNA-binding protein 436006
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Nuclear receptor subfamily 1 group I member 3 0202
Lanosterol 14-alpha demethylase0516
Sterol 14-alpha demethylase0011
Estrogen receptor beta0011
Indoleamine 2,3-dioxygenase 20202
Rap guanine nucleotide exchange factor 42002
ATPase family AAA domain-containing protein 54004
Bile acid receptor0101
14-alpha sterol demethylase 0011
Cysteinyl leukotriene receptor 10202
HSP40, subfamily A [Plasmodium falciparum 3D7]0002
heat shock protein 90, putative0003
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein0101
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10101
5-hydroxytryptamine receptor 2C0303
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0505
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
D0101
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Liver carboxylesterase 10102
Sodium-dependent dopamine transporter0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter0304
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Glutamate receptor ionotropic, NMDA 1 0101
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0101
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0101
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0303
Indoleamine 2,3-dioxygenase 10404
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Histone-lysine N-methyltransferase SUV39H10101
Acetolactate synthase catalytic subunit, mitochondrial0101
Pyruvate kinase PKM0101
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha0101
Protein farnesyltransferase subunit beta0101
Geranylgeranyl transferase type-1 subunit beta0101
Mycothiol S-conjugate amidase0101
Cysteine protease 0101
E3 ubiquitin-protein ligase RNF310101
Histone-lysine N-methyltransferase EHMT20101
RanBP-type and C3HC4-type zinc finger-containing protein 10101
Sharpin0101
Rap guanine nucleotide exchange factor 31001
67.9K protein3003
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
snurportin-11001
muscleblind-like protein 1 isoform 13003
Acid-sensing ion channel 30101
Solute carrier organic anion transporter family member 1A40101
Dihydrofolate reductase0303
Albumin0101
Albumin0011
Cholinesterase0202
Fatty acid-binding protein, intestinal0101
Polyunsaturated fatty acid 5-lipoxygenase0203
UDP-glucuronosyltransferase 2B70103
Prostaglandin G/H synthase 10101
Caspase-10101
Prostaglandin G/H synthase 2 0102
UDP-glucuronosyltransferase 1A30001
Aldo-keto reductase family 1 member C30101
Caspase-30101
Solute carrier organic anion transporter family member 1A10101
Caspase-40101
Caspase-50101
Caspase-90101
Acid-sensing ion channel 10101
Mu-type opioid receptor0303
Fatty-acid amide hydrolase 10101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 1 0102
Dehydrogenase/reductase SDR family member 90101
GALC protein2002
Estrogen receptor beta0102
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Cytochrome P450 2C80101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Cytochrome P450 11B1, mitochondrial0101
Translocator protein0101
Cytochrome P450 7A1 0101
Cytochrome P450 11B2, mitochondrial0101
Estrogen receptor0102
UDP-glucuronosyltransferase 1A1 0101
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Multidrug and toxin extrusion protein 10101
Sodium channel protein type 3 subunit alpha0202
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase IMP-1 0002
Beta-lactamase 0002
Solute carrier family 22 member 30101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] B0101
Synaptic vesicular amine transporter0101
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
serine/threonine-protein kinase PLK11001
Vpr2002
Metabotropic glutamate receptor 60101
Acetylcholinesterase0101
Cytochrome P450 1A20101
Cytochrome P450 1A2 0101
Cannabinoid receptor 10202
Aromatase0011
Melanocortin receptor 40202
Melanocortin receptor 50202
Melanocortin receptor 30202
Type-2 angiotensin II receptor0202
Cholinesterase0101
Calcium release-activated calcium channel protein 10101
methionyl-tRNA synthetase, putative0101
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Nuclear receptor corepressor 20101
DNA gyrase subunit B0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0202
Potassium voltage-gated channel subfamily E member 10101
Potassium voltage-gated channel subfamily KQT member 10101
Beta-lactamase 0001
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase 10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase 0102
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
thioredoxin glutathione reductase1001
chaperonin-containing TCP-1 beta subunit homolog1001
histone acetyltransferase KAT2A isoform 11001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
Carbonic anhydrase 120202
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Carbonic anhydrase 30202
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Carbonic anhydrase 40303
Carbonic anhydrase 60303
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0405
Carbonic anhydrase 70202
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase 90404
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150202
Carbonic anhydrase 130202
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
Carbonic anhydrase 140202
Carbonic anhydrase 5B, mitochondrial0203
5'-AMP-activated protein kinase subunit beta-10001
Carbonic anhydrase0202
Metallo-beta-lactamase type 20101
Angiotensin-converting enzyme0101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 20112
Carbonic anhydrase 5A, mitochondrial0101
Delta-type opioid receptor0101
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 0101
Carbonic anhydrase 130101
Carbonic anhydrase 40101
Protein argonaute-20011
Protein Rev 0011
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase0101
Dihydrofolate reductase 0101
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
NH(3)-dependent NAD(+) synthetase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Metabotropic glutamate receptor 50101
5-hydroxytryptamine receptor 70101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Chain A, CARBONIC ANHYDRASE II0101
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Sigma non-opioid intracellular receptor 10101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Alpha-1D adrenergic receptor0101
D-alanyl-D-alanine dipeptidase0101
atrial natriuretic peptide receptor 1 precursor1001
twin arginine protein translocation system - TatA protein0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]