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trihydroxyflavanone
A hydroxyflavanone carrying three hydroxy substituents.
ChEBI ID: 38739
Members (15)
| Member | Definition | Role |
|---|---|---|
| 8-prenylnaringenin | A trihydroxyflavanone that is (S)-naringenin having a prenyl group at position 8. | sophoraflavanone B |
| abyssinone v | A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7 and 4' and prenyl groups at positions 3' and 5' respectively. | abyssinone V |
| eriocitrin | A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | eriocitrin |
| eriodictyol 7-O-beta-D-glucopyranoside | A flavanone glycoside that is eriodictyol attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is an Nrf2 activator and provides protection against cisplatin-induced toxicity. | eriodictyol 7-O-beta-D-glucopyranoside |
| hesperetin | A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position. | hesperetin |
| homoeriodictyol | A trihydroxyflavanone that consists of 3'-methoxyflavanone in which the three hydroxy substituents are located at positions 4', 5, and 7. | homoeriodictyol |
| kurarinol | A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2' and 4' , a methoxy group at position 5 and a (2S)-5-hydroxy-5-methyl-2-(prop-1-en-2-yl)hexyl group at position 8 respectively. | kurarinol |
| leachianone a | A trihydroxyflavanone that is (2S)-flavanone substituted by a lavandulyl group at position 8, hydroxy groups at positions 5, 7 and 4' and a methoxy group at position 2'. Isolated from the roots of Sophora flavescens and Sophora leachiana, it exhibits antineoplastic and antimalarial activity. | leachianone A |
| naringenin | A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'. | naringenin |
| neoeriocitrin | A flavanone glycoside that is eriodictyol substituted by a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. | neoeriocitrin |
| paclitaxel | A trihydroxyflavanone having a structure of naringenin prenylated at C-6. | 6-prenylnaringenin |
| phellamurin | A member of the class of dihydroflavonols that is (+)-dihydrokaempferol substituted by a prenyl group at position 8 and a beta-D-glucopyranosyl group at position 7 via a glycosidic linkage. Isolated from Phellodendron amurense and Commiphora africana, it exhibits inhibition of intestinal P-glycoprotein. | phellamurin |
| pinobanksin | A trihydroxyflavanone in which the three hydroxy substituents are located at positions 3, 5 and 7. | pinobanksin |
| senegalensin | A trihydroxyflavanone that is (S)-naringenin substituted by prenyl groups at positions 6 and 8. | 6,8-diprenylnaringenin |
| sophoraflavanone a | A trihydroxyflavanone that is (S)-naringenin substituted by a geranyl group at position 8. Isolated from Macaranga bicolor, it exhibits antibacterial and antineoplastic activities. | sophoraflavanone A |
Research
Studies (844)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (0.71) | 18.7374 |
| 1990's | 28 (3.32) | 18.2507 |
| 2000's | 183 (21.68) | 29.6817 |
| 2010's | 452 (53.55) | 24.3611 |
| 2020's | 175 (20.73) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 28 (3.08%) | 5.53% |
| Reviews | 41 (4.51%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 841 (92.42%) | 84.16% |