Page last updated: 2024-08-05 13:09:10

pyrrolopyrazole

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ChEBI ID: 46866

Members (3)

MemberDefinitionRole
4-(2-furanyl)-3-methyl-5-(4-methylphenyl)-2,4-dihydropyrrolo[3,4-c]pyrazol-6-one4-(2-furanyl)-3-methyl-5-(4-methylphenyl)-2,4-dihydropyrrolo[3,4-c]pyrazol-6-one
ly-2157299A pyrrolopyrazole that is 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole which is substituted at positions 2 and 3 by 6-methylpyridin-2-yl and 6-(aminocarbonyl)quinolin-4-yl groups, respectively. A Transforming growth factor-betaRI (TGF-betaRI) kinase inhibitor, it blocks TGF-beta-mediated tumor growth in glioblastoma.LY-2157299
mk-3102omarigliptin

Research

Studies (136)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (0.74)29.6817
2010's88 (64.71)24.3611
2020's47 (34.56)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials21 (15.22%)5.53%
Reviews8 (5.80%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other109 (78.99%)84.16%