Page last updated: 2024-11-12

Mangiferonic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID14034474
CHEMBL ID490331
CHEBI ID172009

Synonyms (8)

Synonym
CHEBI:172009
mangiferonic acid
13878-90-5
(e,6r)-2-methyl-6-[(1s,3r,8r,11s,12s,15r,16r)-7,7,12,16-tetramethyl-6-oxo-15-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]hept-2-enoic acid
CHEMBL490331
(24e)-3-oxo-9,19-cyclolanost-24-en-26-oic acid
9,19-cyclolanost-24-en-26-oic acid, 3-oxo-, (24e)-
DTXSID901316348
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
triterpenoidAny terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (15)

Assay IDTitleYearJournalArticle
AID1616519Antibacterial activity against Klebsiella pneumoniae after 24 hrs by broth microdilution method2019Journal of natural products, 10-25, Volume: 82, Issue:10
Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from
AID1328108Cytotoxicity against human PANC1 cells in Dulbecco's modified Eagle medium measured after 24 hrs by WST8 assay2016Journal of natural products, 08-26, Volume: 79, Issue:8
Chemical Constituents of Mangifera indica and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line.
AID1356584Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs by Griess assay2018Journal of natural products, 08-24, Volume: 81, Issue:8
Structural Characterization of Terpenoids from Abies holophylla Using Computational and Statistical Methods and Their Biological Activities.
AID1616518Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method2019Journal of natural products, 10-25, Volume: 82, Issue:10
Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from
AID1328102Antiausteritic activity against human PANC1 cells in nutrient-deprived medium measured after 24 hrs by WST8 assay2016Journal of natural products, 08-26, Volume: 79, Issue:8
Chemical Constituents of Mangifera indica and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line.
AID430984Cytotoxicity against human PANC1 cells in nutrient-deprived condition assessed as 100% cell death after 24 hrs by WST8 assay2009Journal of natural products, Jul, Volume: 72, Issue:7
Chemical constituents of propolis from Myanmar and their preferential cytotoxicity against a human pancreatic cancer cell line.
AID398516Antiviral activity against HIV1 3B infected in human HOG.R5 assessed as inhibition of viral replication by microtiter assay2003Journal of natural products, Feb, Volume: 66, Issue:2
Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
AID398517Cytotoxicity against human HOG.R5 cells2003Journal of natural products, Feb, Volume: 66, Issue:2
Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
AID1616521Antibacterial activity against Bacillus subtilis after 24 hrs by broth microdilution method2019Journal of natural products, 10-25, Volume: 82, Issue:10
Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from
AID398518Cytotoxicity against human HOG.R5 cells at 20 ug/ml2003Journal of natural products, Feb, Volume: 66, Issue:2
Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
AID430989Cytotoxicity against human PANC1 cells in nutrient-deprived condition assessed as 50% cell death after 24 hrs by WST8 assay2009Journal of natural products, Jul, Volume: 72, Issue:7
Chemical constituents of propolis from Myanmar and their preferential cytotoxicity against a human pancreatic cancer cell line.
AID1356585Cytotoxicity against mouse BV2 cells assessed as cell viability at 20 uM measured after 24 hrs by MTT assay relative to control2018Journal of natural products, 08-24, Volume: 81, Issue:8
Structural Characterization of Terpenoids from Abies holophylla Using Computational and Statistical Methods and Their Biological Activities.
AID1378835Antiausteritic activity against human PANC1 cells in nutrient-deprived medium assessed as decrease in cell viability measured after 24 hrs by WST-8 assay
AID1616520Antibacterial activity against Staphylococcus aureus after 24 hrs by broth microdilution method2019Journal of natural products, 10-25, Volume: 82, Issue:10
Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from
AID398513Antiviral activity against HIV1 3B infected in human HOG.R5 assessed as inhibition of viral replication at 20 ug/ml by microtiter assay2003Journal of natural products, Feb, Volume: 66, Issue:2
Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.68

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.68 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.68)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]