Carcinoma, Mucoepidermoid

A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)

Synonym
Carcinoma, Mucoepidermoid

Excerpt	Reference
"Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands."	( Chen, Y; SiTu, Z; Wu, J, 1996)
"Mucoepidermoid carcinoma is a relatively common neoplasm of the major and minor salivary glands comprising 10-30% of primary carcinomas."	( Johnson, DS; Solomon, AR; Washington, CV, 2001)
"Mucoepidermoid carcinoma is the most common malignant salivary gland tumor, composed of several different cell types, with controversial histogenesis."	( Azevedo, RS; de Almeida, OP; Kowalski, LP; Pires, FR, 2008)
"Mucoepidermoid carcinomas are the most frequent malignant neoplasia of the salivary glands and are histologically classified as low, intermediate, and high grade."	( Bingle, L; González-Arriagada, WA; Ito, FA; Lopes, MA; Santos-Silva, AR; Speight, PM; Vargas, PA, 2012)
"High-grade mucoepidermoid carcinomas are highly aggressive tumours."	( Arrondeau, J; Huguet, F; Lacau St Guily, J; Le Nagat, S; Lefèvre, M; Tassart, M; Touboul, E, 2015)
"Nasopharyngeal mucoepidermoid carcinoma is a rare entity, for which surgical resection is the treatment of choice."	( Chao, SS; Ong, YK; Xu, X, 2016)
"Pulmonary mucoepidermoid carcinoma is an extremely rare intrathoracic malignancy, comprising less than 1% of all lung tumours."	( Argyropoulou, D; Canário, D; Lopes, M; Pedro, PI, 2019)

Excerpt	Reference
"Docetaxel is an active drug for the treatment of mucoepidermoid carcinoma of salivary glands."	( Arrondeau, J; Huguet, F; Lacau St Guily, J; Le Nagat, S; Lefèvre, M; Tassart, M; Touboul, E, 2015)
"However, its effectiveness in treating mucoepidermoid carcinoma (MEC) without such EGFR mutations suggests additional targets."	( Dong, B; Guo, Y; He, Z; Li, S; Qin, J; Sun, Y; Tang, H; Wang, L; Wang, Q; Wu, Y; Yang, S; Yu, H; Zhang, Y, 2019)
"The present case describes the treatment of a mucoepidermoid carcinoma in a 13-year-old female sterilized European domestic cat, using lung lobectomy and -accompanying mitoxantrone chemotherapy."	( Béguin, J; Lamolet, R; Manassero, M; Reyes-Gomez, E, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	31 (14.22)	12.5806
2000's	81 (37.16)	18.1394
2010's	88 (40.37)	28.8240
2020's	18 (8.26)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
benzaldehyde	low	1	0
butyric acid	low	1	0
salicylic acid	low	2	0
formaldehyde	low	1	0
histamine	low	1	0
niacinamide	medium	3	1
thymine	low	1	0
ampiroxicam	low	1	0
bicalutamide	low	1	0
busulfan	low	1	0
dapi	low	1	0
pentetic acid	low	1	0
fluorouracil	medium	5	1
gossypol	low	1	0
guaifenesin	low	3	0
hexamethylene bisacetamide	low	5	0
lidocaine	low	1	0
iohexol	low	1	0
isoniazid	low	1	0
2-propanol	low	1	0
khellin	low	1	0
methoxsalen	low	1	0
mitoxantrone	low	1	0
niflumic acid	low	1	0
nitidine	low	1	0
pd 98059	low	1	0
ono 1078	low	1	0
vorinostat	low	1	0
serine	low	1	0
chloramphenicol	low	1	0
aspartic acid	low	1	0
tyrosine	low	1	0
phenylalanine	low	1	0
cycloheximide	low	1	0
ampicillin	low	1	0
cytarabine	low	1	0
histidine	low	1	0
valine	low	1	0
pyocyanine	low	1	0
acrolein	low	1	0
meglumine	low	1	0
quinazolines	low	10	0
thiazoles	low	2	0
pyrazines	low	1	0
emetine	low	2	0
oleanolic acid	low	1	0
elemene	low	1	0
hematoxylin	low	2	0
eosine yellowish-(ys)	low	2	0
deoxycytidine	low	2	0
carmine	low	3	0
fucose	low	1	0
mannose	low	1	0
titanium	low	3	0
gadolinium	low	2	0
gold	medium	1	1
camptothecin	low	1	0
silver nitrate	low	1	0
tetradecanoylphorbol acetate	low	3	0
daunorubicin	low	1	0
paclitaxel	medium	6	1
etoposide	low	2	0
epirubicin	low	1	0
propiconazole	low	5	0
colforsin	low	1	0
lovastatin	low	1	0
simvastatin	low	1	0
gemcitabine	low	2	0
irinotecan	low	1	0
acridine orange	low	1	0
carbogen	low	1	0
thiazolyl blue	low	1	0
baicalin	low	1	0
thomsen-friedenreich antigen	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	13	0
gliclazide	low	1	0
rosiglitazone	low	1	0
clarithromycin	low	1	0
norcantharidin	low	1	0
paxilline	low	1	0
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid	low	1	0
gefitinib	low	7	0
abiraterone	low	1	0
cd 437	low	1	0
docetaxel anhydrous	low	2	0
4-boronophenylalanine	low	1	0
biotin	low	1	0
erlotinib hydrochloride	low	3	0
lapatinib	low	1	0
sorafenib	medium	2	1
delrin	low	1	0
gossypol acetic acid	low	1	0
bortezomib	low	1	0
carboplatin	low	4	0
glycogen	low	3	0
n-acetylneuraminic acid	low	1	0
inositol 3-phosphate	low	6	0
cephaelin	low	1	0
tapi-2	low	1	0
cefoxitin	low	1	0
bromochloroacetic acid	low	35	0
tolfenamic acid	low	1	0
isomethyleugenol	low	2	0
dibenzylidene acetone	low	1	0
sesquiterpenes	low	1	0
curcumin	low	1	0
thioguanine anhydrous	low	1	0
tamoxifen	low	1	0
3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2h-tetrazolium	low	1	0
rtki cpd	low	2	0
alpha-chymotrypsin	low	1	0
dinoprostone	low	2	0
rosin	low	1	0
leukotriene d4	low	1	0
gamma-linolenic acid	low	1	0
mangostin	low	1	0
phenylephrine hydrochloride	low	2	0
deamino arginine vasopressin	low	1	0
15-hydroxy-5,8,11,13-eicosatetraenoic acid	low	1	0
beta-escin	low	1	0
gadolinium dtpa	low	2	0
clasto-lactacystin beta-lactone	low	1	0
mart-1 antigen	low	1	0
ucn 1028 c	low	1	0
abt-737	low	1	0
nutlin-3a	low	1	0
losartan potassium	low	1	0
indocyanine green	low	1	0
bleomycetin	low	1	0
nad	low	1	0
mdv 3100	low	1	0
hes1 protein, human	low	1	0
ono ae 248	low	1	0
sodium pertechnetate tc 99m	low	1	0
emd1214063	low	1	0
piperidines	low	1	0
interleukin-8	low	3	0
lb-100	low	1	0
apatinib	low	1	0
gsk525762a	low	1	0
alectinib	low	1	0
epidermal growth factor	low	2	0
transforming growth factor beta	low	2	0
cyclin d1	low	7	0
technetium tc 99m sulfur colloid	low	1	0
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	low	1	0
nitrophenols	low	1	0
epoetin alfa	low	1	0
oridonin	low	1	0
transforming growth factor alpha	low	2	0
apicidin	low	1	0
technetium tc 99m medronate	low	1	0
acyclovir	low	1	0
guanine	low	1	0
ganciclovir	low	1	0
trypan blue	low	1	0
nintedanib	medium	1	1
concanavalin a	low	1	0
metallothionein	low	1	0

Protein Targets (1,861)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
ATAD5 protein, partial	17	0	0	17
apical membrane antigen 1, AMA1	10	0	0	10
euchromatic histone-lysine N-methyltransferase 2	38	0	0	38
chromobox protein homolog 1	24	0	0	24
DNA polymerase iota isoform a (long)	19	0	0	19
geminin	44	0	0	44
lethal factor (plasmid)	15	0	1	16
botulinum neurotoxin type A	0	0	1	1
botulinum neurotoxin type F, BoNT/F	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	15	0	0	15
RAR-related orphan receptor gamma	34	0	0	34
GLI family zinc finger 3	32	0	0	32
AR protein	41	0	0	41
aldehyde dehydrogenase 1 family, member A1	29	0	0	29
retinoic acid nuclear receptor alpha variant 1	33	0	0	33
retinoid X nuclear receptor alpha	28	0	0	28
estrogen nuclear receptor alpha	49	0	0	49
peroxisome proliferator-activated receptor delta	22	0	0	22
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	25	0	0	25
activating transcription factor 6	17	0	0	17
v-jun sarcoma virus 17 oncogene homolog (avian)	14	0	0	14
Histone H2A.x	16	0	0	16
thyroid hormone receptor beta isoform a	11	0	0	11
heat shock protein beta-1	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 1	36	0	0	36
lamin isoform A-delta10	27	0	0	27
Voltage-dependent calcium channel gamma-2 subunit	21	0	0	21
Glutamate receptor 2	22	0	0	22
ATP-binding cassette sub-family C member 3	0	28	0	28
Multidrug resistance-associated protein 4	0	28	0	30
Bile salt export pump	0	37	0	37
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 3A4	0	14	3	18
Steroid 21-hydroxylase	0	1	0	1
Aromatase	0	4	0	4
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	27	0	28
Chain A, Apoptosis regulator Bcl-X	0	1	0	1
PPM1D protein	18	0	0	18
EWS/FLI fusion protein	36	0	0	37
Bcl-2-like protein 11	0	1	0	1
Interferon beta	32	0	0	32
Beta-casein	0	1	0	1
Apoptosis regulator Bcl-2	0	7	4	11
Alpha-1B adrenergic receptor	0	7	0	7
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Adenosine receptor A2a	0	1	0	5
BH3-interacting domain death agonist	0	3	0	3
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog	0	0	1	1
Apoptosis regulator BAX	0	1	1	2
Bcl-2-like protein 1	0	6	3	9
Induced myeloid leukemia cell differentiation protein Mcl-1	0	5	1	6
Aspartyl/asparaginyl beta-hydroxylase	0	2	0	2
Bcl-2-related protein A1	0	1	1	2
Bcl-2 homologous antagonist/killer	0	2	1	3
Bcl-2-like protein 2	0	3	0	3
Bcl2-associated agonist of cell death	0	2	0	2
Bcl-2-binding component 3, isoforms 1/2	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
Telomerase reverse transcriptase	0	2	0	2
Amyloid-beta precursor protein	2	3	0	6
Reverse transcriptase/RNaseH	0	2	1	3
thyroid stimulating hormone receptor	12	0	0	12
peroxisome proliferator activated receptor gamma	27	0	0	27
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	13	0	0	13
Chain B, HADH2 protein	13	0	0	13
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Chain A, Ferritin light chain	15	0	0	15
Thymidine kinase	0	2	0	2
thioredoxin reductase	21	0	0	21
phosphopantetheinyl transferase	18	0	0	18
GLS protein	15	0	0	15
TDP1 protein	50	0	0	50
Smad3	14	0	0	14
arylsulfatase A	12	0	0	12
Bloom syndrome protein isoform 1	12	0	0	12
hemoglobin subunit beta	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
Solute carrier family 22 member 1	0	2	0	6
Solute carrier family 22 member 6	0	1	0	2
Bile salt export pump	0	5	0	5
Purine nucleoside phosphorylase	0	3	0	3
Thymidine kinase, cytosolic	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2C9	0	7	1	8
Cytochrome P450 2J2	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	1	0	5
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	4
Thymidine kinase	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	28	0	0	28
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear receptor subfamily 1, group I, member 3	34	0	0	34
cytochrome P450 family 3 subfamily A polypeptide 4	26	0	0	26
glucocorticoid receptor [Homo sapiens]	32	0	0	32
estrogen-related nuclear receptor alpha	38	0	0	38
pregnane X nuclear receptor	25	0	0	25
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
importin subunit beta-1 isoform 1	6	0	0	6
snurportin-1	6	0	0	6
tumor susceptibility gene 101 protein	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
Cyclin-dependent kinase 1	0	3	6	9
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
TAR DNA-binding protein 43	10	1	0	11
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	4	6
ATPase family AAA domain-containing protein 5	19	0	0	19
Ataxin-2	23	0	0	23
Bone morphogenetic protein receptor type-1B	0	0	6	6
Cell division cycle 7-related protein kinase	0	0	4	4
Serine/threonine-protein kinase PLK4	0	1	6	7
ATP-dependent RNA helicase DDX3X	0	0	6	6
Pyridoxal kinase	0	0	6	6
Citron Rho-interacting kinase	0	0	6	6
Serine/threonine-protein kinase Chk1	0	1	7	8
Aurora kinase A	0	1	6	7
Cyclin-G-associated kinase	0	2	6	8
Ephrin type-B receptor 6	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 3	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 2	0	1	6	7
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	6	6
Dynamin-like 120 kDa protein, mitochondrial	0	0	6	6
Eukaryotic translation initiation factor 5B	0	0	3	3
Rho-associated protein kinase 2	0	0	6	6
Serine/threonine-protein kinase ULK1	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	6	6
Ribosomal protein S6 kinase alpha-5	0	0	6	6
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	6	6
Ribosomal protein S6 kinase alpha-4	0	0	6	6
Serine/threonine-protein kinase 16	0	0	6	6
Cyclin-dependent kinase-like 5	0	0	5	5
Serine/threonine-protein kinase 10	0	0	6	6
Serine/threonine-protein kinase D3	0	1	7	8
Structural maintenance of chromosomes protein 2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 6	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	6	6
Serine/threonine-protein kinase LATS1	0	0	6	6
Serine/threonine-protein kinase PAK 4	0	0	6	6
Tyrosine-protein kinase ABL1	0	6	7	13
Epidermal growth factor receptor	0	15	7	22
High affinity nerve growth factor receptor	0	0	6	6
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	5	5
ADP/ATP translocase 2	0	0	6	6
Protein kinase C beta type	0	2	7	9
Insulin receptor	0	4	6	10
Tyrosine-protein kinase Lck	0	3	6	9
Tyrosine-protein kinase Fyn	0	4	6	10
Glycogen phosphorylase, liver form	0	0	6	6
Tyrosine-protein kinase Fes/Fps	0	0	6	6
Adenine phosphoribosyltransferase	0	0	5	5
Tyrosine-protein kinase Yes	0	0	6	6
Tyrosine-protein kinase Lyn	0	1	6	7
Proto-oncogene tyrosine-protein kinase receptor Ret	0	4	6	10
Insulin-like growth factor 1 receptor	0	2	6	8
Signal recognition particle receptor subunit alpha	0	0	5	5
Cytochrome c1, heme protein, mitochondrial	0	0	6	6
Hepatocyte growth factor receptor	0	3	6	9
Tyrosine-protein kinase HCK	0	2	6	8
Proto-oncogene tyrosine-protein kinase ROS	0	2	4	6
Platelet-derived growth factor receptor beta	0	3	6	9
Tyrosine-protein kinase Fgr	0	0	5	5
Serine/threonine-protein kinase A-Raf	0	1	6	7
Mast/stem cell growth factor receptor Kit	0	3	4	7
Glycogen phosphorylase, brain form	0	0	6	6
Breakpoint cluster region protein	0	1	6	7
Serine/threonine-protein kinase pim-1	0	0	6	6
Fibroblast growth factor receptor 1	0	3	6	9
DNA topoisomerase 2-alpha	0	3	6	17
Cyclin-dependent kinase 4	0	2	6	8
ADP/ATP translocase 3	0	0	6	6
Inosine-5'-monophosphate dehydrogenase 2	0	0	6	6
Proto-oncogene tyrosine-protein kinase Src	0	4	6	10
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	6	6
Serine/threonine-protein kinase B-raf	0	4	7	11
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	6	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	6	6
Tyrosine-protein kinase Fer	0	0	6	6
Protein kinase C alpha type	0	2	7	9
cAMP-dependent protein kinase catalytic subunit alpha	0	0	6	6
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	6	6
Casein kinase II subunit alpha'	0	1	6	7
Ras-related protein Rab-6A	0	0	6	6
Ephrin type-A receptor 1	0	0	6	6
Multifunctional protein ADE2	0	0	6	6
cAMP-dependent protein kinase catalytic subunit gamma	0	0	6	6
cAMP-dependent protein kinase catalytic subunit beta	0	0	6	6
Ferrochelatase, mitochondrial	0	0	6	6
Ribosomal protein S6 kinase beta-1	0	0	6	6
Tyrosine-protein kinase JAK1	0	0	6	6
Cyclin-dependent kinase 2	0	3	7	10
Beta-adrenergic receptor kinase 1	0	0	6	6
Probable ATP-dependent RNA helicase DDX6	0	0	6	6
Mitogen-activated protein kinase 3	0	2	6	9
MAP/microtubule affinity-regulating kinase 3	0	0	6	6
Deoxycytidine kinase	0	0	6	9
Mitogen-activated protein kinase 1	0	2	6	8
Ephrin type-A receptor 2	0	0	6	6
Ephrin type-B receptor 2	0	0	6	6
Non-receptor tyrosine-protein kinase TYK2	0	0	6	6
UMP-CMP kinase	0	0	4	4
Phosphatidylethanolamine-binding protein 1	0	0	4	4
Wee1-like protein kinase	0	0	6	6
Heme oxygenase 2	0	0	6	6
S-adenosylmethionine synthase isoform type-2	0	0	6	6
DnaJ homolog subfamily A member 1	0	0	6	6
RAC-alpha serine/threonine-protein kinase	0	0	6	6
RAC-beta serine/threonine-protein kinase	0	0	6	6
Dual specificity protein kinase TTK	0	0	6	6
DNA replication licensing factor MCM4	0	0	6	6
Myosin-10	0	0	4	4
Vascular endothelial growth factor receptor 2	0	8	5	14
Dual specificity mitogen-activated protein kinase kinase 2	0	0	6	6
Receptor-type tyrosine-protein kinase FLT3	0	4	6	10
Bone morphogenetic protein receptor type-1A	0	0	6	6
Activin receptor type-1B	0	0	6	6
TGF-beta receptor type-1	0	0	6	6
TGF-beta receptor type-2	0	0	6	6
Electron transfer flavoprotein subunit beta	0	0	5	5
Tyrosine-protein kinase CSK	0	0	6	6
Glycine--tRNA ligase	0	0	6	6
Protein kinase C iota type	0	1	7	8
Exosome RNA helicase MTR4	0	0	6	6
Tyrosine-protein kinase Tec	0	0	6	6
Tyrosine-protein kinase ABL2	0	0	6	6
Tyrosine-protein kinase FRK	0	0	6	6
G protein-coupled receptor kinase 6	0	0	6	6
Tyrosine-protein kinase SYK	0	1	6	7
26S proteasome regulatory subunit 6B	0	1	6	7
Mitogen-activated protein kinase 8	0	0	6	6
Mitogen-activated protein kinase 9	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 3	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	6	6
Casein kinase I isoform alpha	0	2	6	8
Casein kinase I isoform delta	0	0	6	6
MAP kinase-activated protein kinase 2	0	0	6	6
Elongation factor Tu, mitochondrial	0	0	6	6
Choline-phosphate cytidylyltransferase A	0	0	3	3
Cysteine--tRNA ligase, cytoplasmic	0	0	5	5
Casein kinase I isoform epsilon	0	0	6	6
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	6	6
Dual specificity protein kinase CLK1	0	0	6	6
Dual specificity protein kinase CLK2	0	0	5	5
Dual specificity protein kinase CLK3	0	0	6	6
Glycogen synthase kinase-3 alpha	0	0	6	6
Glycogen synthase kinase-3 beta	0	2	6	8
Cyclin-dependent kinase 7	0	0	6	6
Cyclin-dependent kinase 9	0	0	6	6
Ras-related protein Rab-27A	0	0	6	6
Interleukin-1 receptor-associated kinase 1	0	0	6	6
Ribosomal protein S6 kinase alpha-3	0	0	6	6
Serine/threonine-protein kinase Nek2	0	0	6	6
Serine/threonine-protein kinase Nek3	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 6	0	0	6	6
Serine/threonine-protein kinase PLK1	0	4	6	10
LIM domain kinase 1	0	0	6	6
LIM domain kinase 2	0	0	6	6
Mitogen-activated protein kinase 10	0	0	6	6
Tyrosine--tRNA ligase, cytoplasmic	0	0	5	5
5'-AMP-activated protein kinase subunit gamma-1	0	0	6	7
Ephrin type-B receptor 3	0	0	6	6
Ephrin type-A receptor 5	0	0	6	6
Ephrin type-B receptor 4	0	2	6	8
Ephrin type-A receptor 4	0	0	6	6
Adenylate kinase 2, mitochondrial	0	0	6	6
Adenosine kinase	0	0	6	6
Spike glycoprotein	18	0	4	22
Ras-related protein Rab-10	0	0	6	6
Actin-related protein 3	0	0	6	6
Actin-related protein 2	0	0	6	6
GTP-binding nuclear protein Ran	0	0	6	6
Casein kinase I isoform gamma-2	0	0	5	5
Cyclin-dependent kinase 3	0	0	6	6
Cyclin-dependent kinase 6	0	1	6	7
Cyclin-dependent-like kinase 5	0	0	6	6
Cyclin-dependent kinase 16	0	0	6	6
Cyclin-dependent kinase 17	0	0	6	6
ATP-dependent 6-phosphofructokinase, platelet type	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 1	0	2	6	8
DNA topoisomerase 2-beta	0	1	7	16
Protein kinase C theta type	0	1	7	8
Activin receptor type-1	0	0	6	6
Macrophage-stimulating protein receptor	0	0	6	6
Focal adhesion kinase 1	0	0	6	6
Protein kinase C zeta type	0	1	7	8
Protein kinase C delta type	0	2	7	9
Tyrosine-protein kinase BTK	0	1	6	7
Cyclin-dependent kinase 18	0	0	5	5
Activated CDC42 kinase 1	0	0	6	6
Epithelial discoidin domain-containing receptor 1	0	0	6	6
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	6	6
Tyrosine-protein kinase Mer	0	2	5	7
Serine/threonine-protein kinase 4	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	6	7
Dual specificity mitogen-activated protein kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase 7	0	0	6	6
Serine/threonine-protein kinase PAK 2	0	0	6	6
Serine/threonine-protein kinase 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 1	0	0	6	6
Integrin-linked protein kinase	0	0	6	6
Rho-associated protein kinase 1	0	0	6	6
Non-receptor tyrosine-protein kinase TNK1	0	0	6	6
Serine/threonine-protein kinase ATR	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	6	6
Activin receptor type-2B	0	0	6	6
Bone morphogenetic protein receptor type-2	0	0	6	6
Protein-tyrosine kinase 6	0	0	6	6
cGMP-dependent protein kinase 1	0	0	6	6
Cyclin-dependent kinase 13	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	6	6
Protein-tyrosine kinase 2-beta	0	0	6	6
Maternal embryonic leucine zipper kinase	0	2	6	8
Structural maintenance of chromosomes protein 1A	0	0	6	6
Chromodomain-helicase-DNA-binding protein 4	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 1	0	0	6	6
Cyclin-dependent kinase 10	0	0	3	3
Ephrin type-A receptor 7	0	0	6	6
Delta(24)-sterol reductase	0	0	6	6
Ribosomal protein S6 kinase alpha-1	0	0	6	6
Dual specificity testis-specific protein kinase 1	0	0	6	6
Myosin light chain kinase, smooth muscle	0	0	6	6
Mitogen-activated protein kinase 11	0	0	6	6
Serine/threonine-protein kinase STK11	0	0	6	6
Serine/threonine-protein kinase N1	0	0	6	6
Serine/threonine-protein kinase N2	0	0	6	6
Mitogen-activated protein kinase 14	0	1	6	7
Calcium/calmodulin-dependent protein kinase type IV	0	0	6	6
Mitogen-activated protein kinase kinase kinase 11	0	0	6	6
MAP kinase-activated protein kinase 3	0	0	2	2
Discoidin domain-containing receptor 2	0	1	6	7
AP2-associated protein kinase 1	0	0	6	6
Myosin light chain kinase 3	0	0	6	6
Uncharacterized aarF domain-containing protein kinase 5	0	0	4	4
Putative heat shock protein HSP 90-beta 2	0	0	6	6
Rab-like protein 3	0	0	4	4
Serine/threonine-protein kinase MRCK alpha	0	0	6	6
Serine/threonine-protein kinase MRCK gamma	0	0	6	6
Acyl-CoA dehydrogenase family member 10	0	0	5	5
Serine/threonine-protein kinase N3	0	0	5	5
Serine/threonine-protein kinase ULK3	0	0	6	6
Uncharacterized protein FLJ45252	0	0	6	6
Acyl-CoA dehydrogenase family member 11	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	5	5
Serine/threonine-protein kinase MARK2	0	0	6	6
ATP-dependent RNA helicase DHX30	0	0	5	5
Serine/threonine-protein kinase TAO1	0	0	6	6
STE20-related kinase adapter protein alpha	0	0	6	6
Myosin-14	0	0	5	5
AarF domain-containing protein kinase 1	0	0	6	6
ATP-dependent RNA helicase DDX42	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	6	6
MAP kinase-activated protein kinase 5	0	0	6	6
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	3	3
Misshapen-like kinase 1	0	0	6	6
Atypical kinase COQ8A, mitochondrial	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	6	6
Mitogen-activated protein kinase 15	0	0	6	6
Serine/threonine-protein kinase Nek9	0	0	6	6
ATP-dependent RNA helicase DDX1	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	6	6
Aurora kinase B	0	1	6	7
MAP/microtubule affinity-regulating kinase 4	0	1	6	7
Serine/threonine-protein kinase Nek1	0	0	6	6
PAS domain-containing serine/threonine-protein kinase	0	0	6	6
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	6	6
EKC/KEOPS complex subunit TP53RK	0	0	6	6
Dual specificity testis-specific protein kinase 2	0	0	3	3
SRSF protein kinase 1	0	1	4	5
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	6	6
Mitogen-activated protein kinase kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase kinase kinase 3	0	0	6	6
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	6	6
Nucleolar GTP-binding protein 1	0	0	6	6
Serine/threonine-protein kinase D2	0	0	6	6
NUAK family SNF1-like kinase 2	0	0	6	6
RNA cytidine acetyltransferase	0	0	6	6
Serine/threonine-protein kinase SIK2	0	0	6	6
STE20-like serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO3	0	0	6	6
dCTP pyrophosphatase 1	0	0	6	6
Dual specificity protein kinase CLK4	0	0	5	5
Echinoderm microtubule-associated protein-like 4	0	1	0	1
Casein kinase I isoform gamma-1	0	0	6	6
Serine/threonine-protein kinase PAK 6	0	0	6	6
Phenylalanine--tRNA ligase beta subunit	0	0	6	6
BMP-2-inducible protein kinase	0	0	6	6
Obg-like ATPase 1	0	0	5	5
Midasin	0	0	6	6
Interleukin-1 receptor-associated kinase 4	0	0	6	6
Mitogen-activated protein kinase kinase kinase 20	0	0	6	6
Cyclin-dependent kinase 12	0	0	6	6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	6	6
Serine/threonine-protein kinase pim-2	0	0	5	5
Serine/threonine-protein kinase 26	0	0	5	5
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	5	5
Serine/threonine-protein kinase NLK	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-2	0	0	6	7
Serine/threonine-protein kinase TBK1	0	0	6	6
Septin-9	0	0	6	6
Ribosomal protein S6 kinase alpha-6	0	0	6	6
TRAF2 and NCK-interacting protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO2	0	0	6	6
ALK tyrosine kinase receptor	0	2	5	7
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	2	11
Serine/threonine-protein kinase ICK	0	0	6	6
RAC-gamma serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase SIK3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 2	0	0	6	6
Thyroid hormone receptor-associated protein 3	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 3	0	1	6	7
Serine/threonine-protein kinase MRCK beta	0	0	6	6
Interleukin-1 receptor-associated kinase 3	0	0	6	6
Casein kinase I isoform gamma-3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 4	0	0	6	6
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	13	0	0	13
Chain A, 2-oxoglutarate Oxygenase	23	0	0	23
Chain A, Cruzipain	9	0	0	9
Beta-lactamase	0	0	0	1
acid sphingomyelinase	2	0	0	2
farnesoid X nuclear receptor	25	0	0	25
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	18	0	0	18
thyroid hormone receptor beta isoform 2	35	0	0	35
DNA polymerase beta	6	0	0	6
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase kappa isoform 1	16	0	0	16
Carbonic anhydrase 1	0	5	0	11
Carbonic anhydrase 2	0	6	1	14
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	4	0	4
Angiopoietin-1 receptor	0	1	5	6
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Thiosulfate sulfurtransferase	0	4	0	4
Metallo-beta-lactamase VIM-13	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	4	0	4
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	4	0	4
Metallo-b-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	1	0	2
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
ATP-dependent phosphofructokinase	15	0	0	15
G	17	0	0	17
peripheral myelin protein 22	21	0	0	21
histone acetyltransferase KAT2A isoform 1	18	0	0	18
HLA class I histocompatibility antigen, B alpha chain	17	0	0	17
Cellular tumor antigen p53	36	2	0	38
Inositol hexakisphosphate kinase 1	17	0	0	17
cytochrome P450 2C9, partial	17	0	0	17
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
cytochrome P450 2C19 precursor	9	0	0	9
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	3
Glutamate receptor ionotropic, NMDA 1	0	3	1	9
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	0	8
Glutamate receptor ionotropic, NMDA 2B	0	4	0	9
Glutamate receptor ionotropic, NMDA 2C	0	3	0	8
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	3	0	8
Glutamate receptor ionotropic, NMDA 3B	0	3	0	8
Carbonic anhydrase 4	0	0	0	3
Glutamate receptor ionotropic, NMDA 3A	0	3	0	8
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Lysine-specific histone demethylase 1A	0	4	0	4
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Replicase polyprotein 1ab	0	2	5	7
Replicase polyprotein 1ab	0	3	7	10
G2/mitotic-specific cyclin-B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Trypsin-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	4	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Chain B, SARS CORONAVIRUS MAIN PROTEINASE	0	1	0	1
interleukin 8	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
Polyphenol oxidase 2	0	3	1	6
Botulinum neurotoxin type A	0	2	0	2
Cytochrome P450 2A6	0	3	1	4
Tyrosinase	0	2	0	2
Cytochrome P450 2A5	0	1	0	1
estrogen receptor 2 (ER beta)	24	0	0	24
progesterone receptor	22	0	0	22
aryl hydrocarbon receptor	15	0	0	15
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
tyrosine-protein kinase Yes	7	0	0	7
nuclear receptor ROR-gamma isoform 1	23	0	0	23
Estrogen receptor	0	3	1	5
Glucocorticoid receptor	0	7	1	8
Progesterone receptor	0	1	0	1
Progesterone receptor	0	2	0	2
Glucocorticoid receptor	0	1	0	1
Androgen receptor	0	6	3	11
Androgen receptor	0	11	0	12
Androgen receptor	0	1	0	1
Mineralocorticoid receptor	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Progesterone receptor	0	2	0	2
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
nonstructural protein 1	0	2	0	2
green fluorescent protein, partial	0	1	0	1
vitamin D3 receptor isoform VDRA	20	0	0	20
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	2	0	2
Fumarate hydratase	15	0	0	15
caspase 7, apoptosis-related cysteine protease	12	0	0	12
polyprotein	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	24	0	0	24
caspase-3	12	0	0	12
Caspase-7	7	0	0	7
caspase-3	7	0	0	7
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	2	0	2
Histone deacetylase 3	0	8	1	12
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	2	0	6
Prothrombin	0	1	0	3
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	2	0	6
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	2	0	2
Proteasome subunit beta type-1	0	2	0	3
Carbonic anhydrase 4	0	2	0	6
Carbonic anhydrase 6	0	2	0	6
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	2	0	2
Proteasome subunit alpha type-2	0	2	0	2
Proteasome subunit alpha type-3	0	2	0	2
Proteasome subunit alpha type-4	0	2	0	2
Proteasome subunit beta type-8	0	2	0	2
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	2	0	2
Proteasome subunit alpha type-5	0	2	0	2
Proteasome subunit beta type-4	0	2	0	2
Proteasome subunit beta type-6	0	2	0	2
Proteasome subunit beta type-5	0	5	0	6
Carbonic anhydrase 5A, mitochondrial	0	2	0	6
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	2	0	2
Carbonic anhydrase 7	0	3	0	7
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	2	0	2
Proteasome subunit beta type-2	0	2	0	3
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	2	0	2
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	4	0	4
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	12	2	17
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	3	0	7
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	4
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	2	0	2
Histone deacetylase 2	0	10	2	15
Proteasome subunit beta type-7	0	2	0	2
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	2	0	6
Histone deacetylase 8	0	10	2	15
Histone deacetylase 6	0	10	2	15
Carbonic anhydrase 14	0	2	0	6
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	0	6
thyroid stimulating hormone receptor	10	0	0	10
Nuclear receptor ROR-gamma	7	0	0	7
15-lipoxygenase, partial	12	0	0	12
Matrix metalloproteinase-9	0	1	0	1
Chain A, Nitrile Hydratase alpha subunit	0	1	0	1
Chain B, Nitrile Hydratase beta subunit	0	1	0	1
SMAD family member 2	13	0	0	13
SMAD family member 3	13	0	0	13
Lysine-specific demethylase 4E	0	2	0	2
Free fatty acid receptor 3	0	0	1	1
Histone deacetylase 4	0	7	1	11
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Histone deacetylase 7	0	7	2	12
Polyamine deacetylase HDAC10	0	6	1	10
Histone deacetylase 11	0	6	1	10
Histone deacetylase 9	0	7	1	11
Histone deacetylase 5	0	7	1	11
Methyl-accepting chemotaxis protein NahY	0	0	1	1
DNA topoisomerase	0	1	0	1
NFKB1 protein, partial	4	0	0	4
Thrombopoietin	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
regulator of G-protein signaling 4	12	0	0	12
67.9K protein	24	0	0	24
glucocerebrosidase	6	0	0	6
putative alpha-glucosidase	1	0	0	1
alpha-galactosidase	2	0	0	2
lysosomal alpha-glucosidase preproprotein	7	0	0	7
peripheral myelin protein 22 isoform 1	6	0	0	6
cellular tumor antigen p53 isoform a	13	0	0	13
huntingtin isoform 2	8	0	0	8
ras-related protein Rab-9A	8	0	0	8
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
survival motor neuron protein isoform d	18	0	0	18
cytochrome P450 3A4 isoform 1	22	0	0	22
M-phase phosphoprotein 8	7	0	0	7
muscleblind-like protein 1 isoform 1	8	0	0	8
relaxin receptor 1 isoform 1	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	22	1	0	23
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
DNA ligase	0	1	0	1
Integrin beta-3	12	1	0	13
Integrin alpha-IIb	12	0	0	12
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	2	1	10
Gamma-aminobutyric acid receptor subunit beta-1	22	1	0	23
Gamma-aminobutyric acid receptor subunit delta	22	1	0	23
Gamma-aminobutyric acid receptor subunit gamma-2	22	1	0	23
Gamma-aminobutyric acid receptor subunit alpha-5	22	1	0	23
Gamma-aminobutyric acid receptor subunit alpha-3	22	1	0	23
Gamma-aminobutyric acid receptor subunit gamma-1	22	1	0	23
Gamma-aminobutyric acid receptor subunit alpha-2	22	1	0	23
Type-2 restriction enzyme BamHI	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	22	1	0	23
Gamma-aminobutyric acid receptor subunit gamma-3	22	1	0	23
Gamma-aminobutyric acid receptor subunit alpha-6	22	1	0	23
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	5	0	5
Type-2 restriction enzyme HindIII	0	1	0	1
D(1A) dopamine receptor	4	1	0	5
Ribonuclease pancreatic	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	22	1	0	23
Gamma-aminobutyric acid receptor subunit beta-3	22	1	0	23
Gamma-aminobutyric acid receptor subunit beta-2	22	1	0	23
Inositol monophosphatase 1	8	0	0	8
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Integrase	0	3	0	3
GABA theta subunit	22	1	0	23
DNA topoisomerase type IB small subunit	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	22	1	0	23
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
acetylcholinesterase	10	0	0	10
cytochrome P450 2D6	14	0	0	14
histone-lysine N-methyltransferase 2A isoform 2 precursor	7	0	0	7
Luciferase	17	0	0	17
USP1 protein, partial	18	0	0	18
Microtubule-associated protein tau	19	0	0	19
luciferase	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	7	0	0	7
mitogen-activated protein kinase 1	17	0	0	17
flap endonuclease 1	15	0	0	15
eyes absent homolog 2 isoform a	2	0	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	7	0	9
Glutamate receptor 1	2	0	0	2
Glutamate receptor 3	2	0	0	2
Glutamate receptor 4	2	0	0	2
Tyrosine-protein phosphatase 1	0	1	0	1
Alpha-synuclein	7	1	1	9
C-terminal-binding protein 1	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	0	0	10
Retinoic acid receptor alpha	0	1	1	2
Retinoic acid receptor beta	0	1	1	2
Retinoic acid receptor gamma	0	1	1	2
Histamine H2 receptor	14	1	1	16
streptokinase A precursor	0	0	4	4
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Methionine--tRNA ligase, mitochondrial	0	0	1	1
urokinase-type plasminogen activator precursor	10	0	0	10
plasminogen precursor	10	0	0	10
urokinase plasminogen activator surface receptor precursor	10	0	0	10
ATP-dependent translocase ABCB1	0	13	4	22
Solute carrier organic anion transporter family member 1B3	0	9	0	10
Solute carrier organic anion transporter family member 1B1	0	7	0	7
glp-1 receptor, partial	13	0	0	13
pregnane X receptor	9	0	0	9
nuclear receptor subfamily 0 group B member 1	0	2	0	2
steroidogenic factor 1	0	2	0	2
relaxin receptor 2 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Rap guanine nucleotide exchange factor 3	4	0	0	4
5-hydroxytryptamine receptor 1A	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 1	0	3	1	4
Adenylate cyclase type 2	0	0	1	1
Adenylate cyclase type 8	0	0	1	1
Adenylate cyclase type 1	0	1	1	2
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Nrf2	3	0	0	3
alkaline phosphatase, intestinal	0	1	1	2
thioredoxin glutathione reductase	8	0	0	8
PINK1	4	0	0	4
Parkin	7	0	0	7
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
toll-like receptor 9	0	1	0	1
IDH1	14	0	0	14
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	8	0	0	8
TPA: protein transporter TIM10	0	2	0	2
thyrotropin-releasing hormone receptor	4	0	0	4
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	1	2
perilipin-5	0	2	0	2
intestinal alkaline phosphatase precursor	0	1	1	2
perilipin-1	0	2	0	2
transcriptional regulator ERG isoform 3	5	0	0	5
pyruvate kinase PKM isoform a	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	1	0	3
alkaline phosphatase, germ cell type preproprotein	0	1	1	2
caspase-1 isoform alpha precursor	3	0	0	3
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	5	0	0	5
neuropeptide S receptor isoform A	4	0	0	4
Prostaglandin E synthase	0	1	0	1
Acetylcholinesterase	0	2	0	2
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cholinesterase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
60 kDa chaperonin	0	3	0	3
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	4	0	4
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	3	0	3
Glycogen synthase kinase-3 beta	0	1	0	1
Amine oxidase [flavin-containing] A	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Acetylcholinesterase	0	5	0	5
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Amine oxidase [flavin-containing] B	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Prostaglandin G/H synthase 2	0	8	4	12
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Alpha-1A adrenergic receptor	0	6	0	6
Caspase-7	3	0	0	3
Beta-secretase 1	0	3	0	3
Guanine nucleotide-binding protein G	4	0	0	4
Cholinesterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	1	2
Serine/threonine-protein kinase PAK 1	0	1	4	5
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	2	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	1	1	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	3	0	3
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
P53	1	0	0	1
RPL19A	0	0	1	1
Spike glycoprotein	0	0	4	4
Replicase polyprotein 1ab	0	0	4	4
NPC intracellular cholesterol transporter 1 precursor	8	0	0	8
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	5	0	5
COUP transcription factor 2 isoform a	0	1	0	1
Transmembrane protease serine 2	0	0	4	4
Glucose transporter	0	2	0	2
Hexose transporter 1	0	2	0	2
Procathepsin L	0	0	4	4
Replicase polyprotein 1a	0	0	4	4
Replicase polyprotein 1ab	0	0	4	4
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	2	0	3
Endothelial PAS domain-containing protein 1	0	2	0	3
Angiotensin-converting enzyme 2	0	0	4	4
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	2
endonuclease IV	4	0	0	4
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	3	0	4
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	1	5	1	7
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Prothrombin	0	1	0	1
Glandular kallikrein	0	1	0	1
Cell division protein FtsZ	0	0	1	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Transthyretin	0	1	2	3
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	3	0	5
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
BRCA1	1	0	0	1
WRN	4	0	0	4
nonstructural protein 1	7	0	0	7
Heat shock protein hsp-16.2	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Vpr	5	0	0	5
Protein skinhead-1	0	1	0	1
Glycoprotein hormones alpha chain	2	0	0	2
Cytochrome P450 1A2	0	7	0	7
Cytochrome P450 2D6	0	5	0	5
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier family 22 member 2	0	2	0	4
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Serum paraoxonase/arylesterase 1	0	3	0	3
Kinesin-like protein KIF11	0	2	0	2
Nucleotide-binding oligomerization domain-containing protein 2	0	2	0	2
Membrane-associated progesterone receptor component 1	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	5	5
Serine/threonine-protein kinase Nek7	0	0	5	5
Isoleucine--tRNA ligase, mitochondrial	0	0	4	4
Long-chain-fatty-acid--CoA ligase 5	0	0	5	5
Serine/threonine-protein kinase 38-like	0	0	5	5
NS5	0	0	1	1
Serine hydrolase RBBP9	0	1	0	1
Alpha-2A adrenergic receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	4	0	4
Dihydroorotate dehydrogenase	0	1	0	1
Genome polyprotein	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	2
Receptor tyrosine-protein kinase erbB-2	0	8	4	12
Serine/threonine-protein kinase B-raf	0	2	0	2
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
DNA topoisomerase 2	0	0	0	2
ATP-dependent translocase ABCB1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	3
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Tubulin beta-2B chain	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	0	3
Glycine receptor subunit alpha-1	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-4	3	0	0	3
Neuronal acetylcholine receptor subunit beta-2	3	0	0	3
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Solute carrier family 22 member 8	0	0	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Fucose-binding lectin PA-IIL	0	2	0	2
CD209 antigen	0	3	0	3
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
serine/threonine-protein kinase PLK1	4	0	0	4
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Free fatty acid receptor 1	0	0	2	2
Trypsin	0	1	0	2
Coagulation factor VII	0	2	0	2
ClpP	2	0	0	2
Transitional endoplasmic reticulum ATPase	0	1	0	1
Leukotriene C4 synthase	0	0	4	4
epidermal growth factor receptor isoform a precursor	1	1	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	2	4	6
Serine/threonine-protein kinase 25	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	4	4
Serine/threonine-protein kinase RIO3	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 7	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	4	5
Peripheral plasma membrane protein CASK	0	0	4	4
Serine/threonine-protein kinase DCLK1	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	4	4
Muscle, skeletal receptor tyrosine-protein kinase	0	0	4	4
Mitogen-activated protein kinase 13	0	0	4	4
3-phosphoinositide-dependent protein kinase 1	0	0	4	4
Mitogen-activated protein kinase kinase kinase 13	0	0	4	4
Death-associated protein kinase 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
NUAK family SNF1-like kinase 1	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	4	4
Tyrosine-protein kinase JAK2	0	1	4	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	4	4
Serine/threonine-protein kinase PAK 3	0	0	4	4
Serine/threonine-protein kinase 17B	0	0	4	4
Cyclin-dependent kinase 14	0	0	4	4
Serine/threonine-protein kinase OSR1	0	0	4	4
Serine/threonine-protein kinase Chk2	0	0	4	4
RAF proto-oncogene serine/threonine-protein kinase	0	3	4	7
Cytochrome P450 2E1	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	4	5
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	4	4
Uncharacterized serine/threonine-protein kinase SBK3	0	0	4	4
Cytochrome P450 2C8	0	3	0	3
Myosin light chain kinase, smooth muscle	0	0	3	3
Insulin receptor-related protein	0	0	4	4
Platelet-derived growth factor receptor alpha	0	3	4	7
Vascular endothelial growth factor receptor 1	0	2	4	6
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	4	4
Serine/threonine-protein kinase MAK	0	0	4	4
Cyclin-dependent kinase 11B	0	0	4	4
Fibroblast growth factor receptor 2	0	1	4	5
Receptor tyrosine-protein kinase erbB-3	0	1	4	5
Fibroblast growth factor receptor 4	0	1	4	5
Fibroblast growth factor receptor 3	0	1	4	5
Sodium-dependent dopamine transporter	0	1	0	1
Protein kinase C eta type	0	1	5	6
Cruzipain	0	2	0	2
Activin receptor type-2A	0	0	4	4
Ephrin type-A receptor 3	0	0	4	4
Ephrin type-A receptor 8	0	0	4	4
Leukocyte tyrosine kinase receptor	0	0	4	4
Tyrosine-protein kinase receptor UFO	0	0	4	4
Mitogen-activated protein kinase 4	0	0	4	4
G protein-coupled receptor kinase 4	0	0	4	4
Cytochrome P450 2C19	0	6	0	6
Type-1 angiotensin II receptor	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	0	4	4
Vascular endothelial growth factor receptor 3	0	2	4	6
Serine/threonine-protein kinase receptor R3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	3	4	7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	4	6
Serine/threonine-protein kinase mTOR	0	2	4	6
Megakaryocyte-associated tyrosine-protein kinase	0	0	4	4
Tyrosine-protein kinase TXK	0	0	4	4
Tyrosine-protein kinase ZAP-70	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	4	6
Cyclin-dependent kinase 8	0	1	4	5
Tyrosine-protein kinase Blk	0	0	4	4
Cytoplasmic tyrosine-protein kinase BMX	0	0	4	4
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	4	4
Serine/threonine-protein kinase Nek4	0	0	4	4
Tyrosine-protein kinase JAK3	0	1	4	5
Death-associated protein kinase 1	0	1	4	5
Mitogen-activated protein kinase 12	0	0	4	4
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	4	5
Ephrin type-B receptor 1	0	0	4	4
Hormonally up-regulated neu tumor-associated kinase	0	0	4	4
Serine/threonine-protein kinase SIK1	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 4	0	0	4	4
Cell division control protein 2 homolog	0	0	4	4
Calcium-dependent protein kinase 1	0	0	4	4
Tubulin alpha-1A chain	0	0	3	3
Casein kinase II subunit alpha	0	1	4	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	4	4
SRSF protein kinase 2	0	0	4	4
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Mitogen-activated protein kinase kinase kinase 9	0	0	4	4
Serine/threonine-protein kinase PknB	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	4	4
Synaptic vesicular amine transporter	0	1	0	1
Protein kinase C epsilon type	0	2	5	7
Mitogen-activated protein kinase kinase kinase 10	0	0	4	4
Tyrosine-protein kinase receptor TYRO3	0	0	4	4
Tyrosine-protein kinase ITK/TSK	0	0	4	4
Myotonin-protein kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 12	0	0	4	4
cGMP-dependent protein kinase 2	0	0	4	4
Serine/threonine-protein kinase PRP4 homolog	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 1	0	1	4	5
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1	0	0	4	4
Serine/threonine-protein kinase D1	0	1	5	6
Serine/threonine-protein kinase 38	0	0	4	4
Receptor tyrosine-protein kinase erbB-4	0	2	4	6
Ribosomal protein S6 kinase alpha-2	0	0	4	4
Rhodopsin kinase GRK1	0	0	4	4
NT-3 growth factor receptor	0	0	4	4
BDNF/NT-3 growth factors receptor	0	0	4	4
Mitogen-activated protein kinase 6	0	0	4	4
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	4	4
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	4	4
Mitogen-activated protein kinase kinase kinase 19	0	0	4	4
Serine/threonine-protein kinase TNNI3K	0	1	4	5
Serine/threonine-protein kinase Nek5	0	0	4	4
Dual serine/threonine and tyrosine protein kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 15	0	0	4	4
Serine/threonine-protein kinase tousled-like 2	0	0	4	4
Serine/threonine-protein kinase 32C	0	0	4	4
Serine/threonine-protein kinase pim-3	0	0	4	4
Serine/threonine-protein kinase VRK2	0	0	4	4
Myosin light chain kinase family member 4	0	0	4	4
Homeodomain-interacting protein kinase 1	0	1	4	5
Calcium/calmodulin-dependent protein kinase type 1D	0	0	4	4
Cyclin-dependent kinase-like 3	0	0	4	4
Serine/threonine-protein kinase BRSK2	0	0	4	4
Serine/threonine-protein kinase NIM1	0	0	4	4
Serine/threonine-protein kinase ULK2	0	0	4	4
Serine/threonine-protein kinase DCLK2	0	0	4	4
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	4	4
Casein kinase I isoform alpha-like	0	0	4	4
Homeodomain-interacting protein kinase 4	0	1	4	5
Myosin-IIIa	0	0	4	4
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	4	4
Serine/threonine-protein kinase Nek11	0	0	4	4
Serine/threonine-protein kinase BRSK1	0	0	4	4
Serine/threonine-protein kinase 35	0	0	4	4
Rhodopsin kinase GRK7	0	0	4	4
Serine/threonine-protein kinase 32A	0	0	4	4
Myosin-IIIb	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	4	4
Cyclin-dependent kinase-like 2	0	0	4	4
Serine/threonine-protein kinase Sgk3	0	0	4	4
Atypical kinase COQ8B, mitochondrial	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1G	0	0	4	4
Cyclin-dependent kinase 15	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	4	4
Serine/threonine-protein kinase RIO1	0	0	4	4
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase RIO2	0	0	4	4
Cyclin-dependent kinase 19	0	1	4	5
Transient receptor potential cation channel subfamily M member 6	0	0	4	4
Testis-specific serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase 33	0	0	4	4
Serine/threonine-protein kinase DCLK3	0	0	4	4
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	4	4
Homeodomain-interacting protein kinase 2	0	1	4	5
Tyrosine-protein kinase Srms	0	0	4	4
Homeodomain-interacting protein kinase 3	0	1	4	5
Serine/threonine-protein kinase PLK3	0	1	4	5
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	4	5
Serine/threonine-protein kinase Nek6	0	0	4	4
SNF-related serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase LATS2	0	0	4	4
Serine/threonine-protein kinase 36	0	0	4	4
Serine/threonine-protein kinase 32B	0	0	4	4
Serine/threonine-protein kinase PLK2	0	1	4	5
Serine/threonine-protein kinase MARK1	0	0	4	4
Serine/threonine-protein kinase PAK 5	0	0	4	4
eIF-2-alpha kinase GCN2	0	0	4	4
Phosphatidylinositol 4-kinase beta	0	0	4	4
Serine/threonine-protein kinase 17A	0	0	4	4
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	4	4
Ephrin type-A receptor 6	0	0	4	4
Death-associated protein kinase 2	0	0	4	4
Serine/threonine-protein kinase tousled-like 1	0	0	4	4
SRSF protein kinase 3	0	0	4	4
Cyclin-dependent kinase 11A	0	0	4	4
Aurora kinase C	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	4	4
Microtubule-associated serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase 24	0	0	4	4
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Equilibrative nucleoside transporter 1	0	1	0	1
Mcl-1	0	3	0	3
Estrogen receptor 1	0	1	0	1
DNA polymerase III, partial	3	0	0	3
cytochrome P450 2D6 isoform 1	8	0	0	8
galactokinase	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
cytochrome P450 2C9 precursor	5	0	0	5
D(1A) dopamine receptor	2	0	0	2
glucokinase regulatory protein	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase	1	0	0	1
Prolyl endopeptidase	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Beta-lactamase	0	1	0	1
L-lactate dehydrogenase B chain	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	1	3
Muscarinic acetylcholine receptor M3	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	1	3
Muscarinic acetylcholine receptor M5	0	2	1	3
Muscarinic acetylcholine receptor M2	0	2	1	3
Malate dehydrogenase, cytoplasmic	0	1	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
L-lactate dehydrogenase B chain	0	1	0	1
DNA-3-methyladenine glycosylase	0	1	0	1
Caspase-1	1	1	0	2
DNA repair protein RAD52 homolog	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Type 1 InsP3 receptor isoform S2	1	0	0	1
Peroxisome proliferator-activated receptor alpha	1	2	1	4
L-lactate dehydrogenase	0	1	0	1
L-lactate dehydrogenase	0	1	0	1
L-lactate dehydrogenase B chain	0	1	0	1
L-lactate dehydrogenase	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Histamine H3 receptor	1	0	0	1
phosphoglycerate kinase	3	0	0	3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Valosin-containing protein	0	1	0	1
pyruvate kinase	4	0	0	4
estrogen receptor beta isoform 1	0	1	0	1
Endothelin receptor type B	2	0	0	2
Adenosine receptor A1	1	0	0	5
Endothelin-1 receptor	2	0	0	2
Chain A, Bromodomain-containing protein 4	0	0	1	1
Bromodomain-containing protein 4	0	3	2	5
Bromodomain-containing protein 2	0	2	1	3
Bromodomain-containing protein 3	0	2	1	3
Bromodomain testis-specific protein	0	0	1	1
ATPase family AAA domain-containing protein 2	0	0	1	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	2	2
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
hypothetical protein, conserved	3	0	0	3
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
endoribonuclease toxin MazF	0	0	1	1
Pyruvate kinase PKM	0	1	1	2
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	4	0	0	4
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 3	0	3	0	4
Plasma kallikrein	0	0	0	4
Macrophage migration inhibitory factor	0	3	0	3
Histamine H2 receptor	0	3	2	5
Histamine H1 receptor	0	1	2	3
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H1 receptor	0	2	2	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	5
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	0	0	5
Solute carrier family 22 member 1	0	1	0	2
Carbonic anhydrase	0	0	0	5
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 13	0	1	0	4
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Histamine H3 receptor	0	1	2	3
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	4	0	5
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	3
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M4	0	6	0	6
Liver carboxylesterase 1	0	1	0	2
Multidrug and toxin extrusion protein 2	0	2	0	2
Multidrug and toxin extrusion protein 1	0	3	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA gyrase subunit B	0	2	0	3
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Chain A, Epidermal growth factor receptor	0	1	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Cytochrome P450 3A5	0	2	1	3
G1/S-specific cyclin-E1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Alpha-1A adrenergic receptor	0	1	0	1
Cysteinyl leukotriene receptor 2	0	1	1	2
Cysteinyl leukotriene receptor 1	0	3	1	4
muscarinic acetylcholine receptor M1	4	0	0	4
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
bcl-2-related protein A1	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	6	0	6
Insulin receptor	0	2	0	2
Integrin alpha-L	0	1	1	2
Substance-K receptor	0	6	0	6
Sodium-dependent noradrenaline transporter	0	6	1	7
Adenosine receptor A1	0	4	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Sodium-dependent dopamine transporter	0	4	0	4
Lanosterol 14-alpha demethylase	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ	0	1	0	1
Maltase-glucoamylase, intestinal	0	2	0	2
Isocitrate dehydrogenase [NADP] cytoplasmic	0	1	0	1
Lysosomal alpha-glucosidase	0	2	0	2
Sialidase	0	2	0	2
Sucrase-isomaltase, intestinal	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	2
Sphingomyelin phosphodiesterase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	2
Phosphoglycerate mutase 1	0	1	0	1
Delta-type opioid receptor	0	1	2	3
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Fatty acid synthase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Sphingomyelin phosphodiesterase	0	1	0	1
Probable maltase-glucoamylase 2	0	2	0	2
Stimulator of interferon genes protein	0	0	1	1
Stimulator of interferon genes protein	0	1	1	2
Cyclic GMP-AMP synthase	0	1	0	1
Alpha-mannosidase 2C1	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	3
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Prostate-specific antigen	0	1	0	1
Amine oxidase [flavin-containing] B	0	3	0	3
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
dopamine D1 receptor	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Protein-arginine deiminase type-4	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
LANA	0	0	0	1
phospholipase A2, group III	0	1	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
protein AF-9 isoform a	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
pyruvate kinase PKM isoform b	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
5-hydroxytryptamine receptor 4	0	4	0	4
Muscarinic acetylcholine receptor M2	0	4	0	4
Ornithine decarboxylase	3	0	0	3
Muscarinic acetylcholine receptor M1	0	4	0	4
Angiotensin-converting enzyme	0	4	0	4
5-hydroxytryptamine receptor 2C	0	5	0	5
Casein kinase II subunit beta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
Single-stranded DNA cytosine deaminase	1	0	0	1
P2Y purinoceptor 12	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	3	0	3
NAD-dependent protein deacetylase	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
histone deacetylase 9 isoform 3	2	0	0	2
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	6
Transcription factor SOX-18	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Transcriptional enhancer factor TEF-3	0	1	1	2
G-protein coupled receptor 35	0	2	1	3
Platelet-derived growth factor receptor beta	0	2	0	2
Platelet-derived growth factor receptor alpha	0	1	0	1
Vascular endothelial growth factor receptor 2	0	2	0	2
Aromatic-L-amino-acid decarboxylase	0	1	0	1
PPP5C protein, partial	0	1	0	1
serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 3	0	1	0	1
Protein Mdm4	0	2	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Peptidyl-prolyl cis-trans isomerase D	0	1	0	1
Mu-type opioid receptor	0	0	1	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Albumin	0	2	1	3
Phosphotyrosine protein phosphatase	0	1	0	1
Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]	0	0	1	1
Aldo-keto reductase family 1 member B10	0	2	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Pancreatic alpha-amylase	0	1	0	3
DNA polymerase beta	0	1	0	1
DNA polymerase beta	0	1	0	1
Receptor-type tyrosine-protein phosphatase C	0	1	0	1
Receptor-type tyrosine-protein phosphatase F	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Receptor-type tyrosine-protein phosphatase alpha	0	1	0	1
Receptor-type tyrosine-protein phosphatase epsilon	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Dual specificity protein phosphatase 3	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
Env polyprotein	0	0	1	1
G-protein coupled bile acid receptor 1	0	0	1	1
Prolyl hydroxylase EGLN2	0	0	1	1
Egl nine homolog 1	0	0	1	1
Prolyl hydroxylase EGLN3	0	0	1	1
Transmembrane prolyl 4-hydroxylase	0	0	1	1
Protease	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Cysteinyl leukotriene receptor 1	0	1	0	1
Bile acid receptor	0	0	1	1
Tubulin alpha-1A chain	0	1	1	3
Tubulin beta chain	0	1	1	2
Tubulin beta-4A chain	0	1	1	3
Integrin alpha-V	0	1	0	1
Tubulin beta chain	0	1	1	3
Tubulin alpha-3C chain	0	1	1	3
UDP-glucuronosyltransferase 1-6	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Delta-type opioid receptor	0	5	0	5
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	1	1	3
Beta-tubulin	0	1	0	1
Tubulin beta-8 chain	0	1	1	3
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
POsterior Segregation	0	0	1	1
Zinc finger protein mex-5	0	0	1	1
BZLF2	0	1	0	1
Luciferin 4-monooxygenase	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	1	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Catechol O-methyltransferase	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Thromboxane-A synthase	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	2	2	5
Peroxisome proliferator-activated receptor gamma	0	0	1	1
C-C chemokine receptor type 2	0	1	0	1
Cannabinoid receptor 2	0	0	1	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	2	1	3
Glutamate receptor ionotropic, NMDA 1	0	0	1	1
ATP-binding cassette sub-family C member 8	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	1
Glutamate receptor ionotropic, NMDA 2B	0	0	1	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	1	1
Thrombin	0	0	1	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Amino acid transporter	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
melanocortin receptor 4	0	1	1	2
Tyrosine-protein kinase ABL1	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-C	0	1	1	2
5-hydroxytryptamine receptor 2A	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	3	0	3
Protein delta homolog 1	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
Chain A, CES1 protein	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	2	1	3
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	2
Beta-1 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Adenosine receptor A3	0	4	0	4
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	0	3
Muscarinic acetylcholine receptor M3	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Substance-P receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Adenosine receptor A2a	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	2	0	2
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Estrogen receptor beta	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
PAX8	0	0	0	2
Thymidine phosphorylase	0	1	0	1
phospholipase A2 precursor	0	1	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
cysteine protease ATG4B isoform a	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Cadherin-1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Adenomatous polyposis coli protein	0	1	0	1
Catenin beta-1	0	2	0	2
Transcription factor 7-like 2	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Histone deacetylase 8	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Histone deacetylase	0	1	0	1
Gli1	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
Histone deacetylase 1	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Nuclear receptor corepressor 1	0	2	0	2
Protein Tat	0	0	1	1
Heat shock protein HSP 90-alpha	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Histone deacetylase 1	0	1	0	1
Histone deacetylase	0	1	0	1
Renin	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	1	3
Histone deacetylase	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Carboxypeptidase B2	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
REST corepressor 3	0	1	0	1
Histone deacetylase	0	1	0	1
Nuclear receptor corepressor 2	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (218)

Protein Targets (1,861)

Carcinoma, Mucoepidermoid

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (218)

Drugs Studied (180)

Protein Targets (1,861)