Page last updated: 2024-10-28

ibuprofen and Injuries

ibuprofen has been researched along with Injuries in 20 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
"To compare an ibuprofen-releasing foam dressing (Biatain Ibu, ColoplastA/S) with local best practice in the treatment of painful exuding wounds."9.13Effect of an ibuprofen-releasing foam dressing on wound pain: a real-life RCT. ( Altindas, M; Johannesen, N; Jortikka, A; Orsted, H; Palao i Domenech, R; Persson, LM; Ram, A; Romanelli, M; Schäfer, E; Slonková, V; Tsiftsis, DD, 2008)
"To evaluate the analgesic efficacy and safety of ibuprofen in children with musculoskeletal injuries."9.12Efficacy and safety of ibuprofen in children with musculoskeletal injuries: A systematic review and meta-analysis of randomized controlled trials. ( Jin, J; Wan, Z; Wang, J; Wang, X, 2021)
"Our goal was to determine which of 3 analgesics, acetaminophen, ibuprofen, or codeine, given as a single dose, provides the most efficacious analgesia for children presenting to the emergency department with pain from acute musculoskeletal injuries."9.12A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. ( Clark, E; Correll, R; Gaboury, I; Passi, B; Plint, AC, 2007)
"To evaluate the efficacy of IM ketorolac versus that of oral ibuprofen in acute musculoskeletal pain."9.08Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain. ( Paris, PM; Seaberg, DC; Turturro, MA, 1995)
"To examine if wound aetiology has an effect on the pain-relieving properties of an ibuprofen-releasing foam dressing, which was previously shown to reduce pain in wounds of various aetiologies, compared with local best practice (LBP)."7.77Analgesic efficacy of an ibuprofen-releasing foam dressing compared with local best practice for painful exuding wounds. ( Arapoglou, V; Dimakakos, EP; Gjødsbøl, K; Glynn, C; Katsenis, K; Petersen, B; Schäfer, E; Syrigos, KN; Tsoutos, D; Zakopoulou, N, 2011)
"This study aimed to compare the analgesic efficacy of topical ibuprofen and topical piroxicam for acute musculoskeletal injuries."5.34Comparison of ibuprofen and piroxicam gel in the treatment of trauma pain: A randomized double-blind trial of geriatric population. ( Akbas, I; Cakir, Z; Dogruyol, S; Dogruyol, T; Gur, STA; Kocak, AO; Menekse, TS, 2020)
"To compare an ibuprofen-releasing foam dressing (Biatain Ibu, ColoplastA/S) with local best practice in the treatment of painful exuding wounds."5.13Effect of an ibuprofen-releasing foam dressing on wound pain: a real-life RCT. ( Altindas, M; Johannesen, N; Jortikka, A; Orsted, H; Palao i Domenech, R; Persson, LM; Ram, A; Romanelli, M; Schäfer, E; Slonková, V; Tsiftsis, DD, 2008)
"To evaluate the analgesic efficacy and safety of ibuprofen in children with musculoskeletal injuries."5.12Efficacy and safety of ibuprofen in children with musculoskeletal injuries: A systematic review and meta-analysis of randomized controlled trials. ( Jin, J; Wan, Z; Wang, J; Wang, X, 2021)
"Our goal was to determine which of 3 analgesics, acetaminophen, ibuprofen, or codeine, given as a single dose, provides the most efficacious analgesia for children presenting to the emergency department with pain from acute musculoskeletal injuries."5.12A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. ( Clark, E; Correll, R; Gaboury, I; Passi, B; Plint, AC, 2007)
"To evaluate the efficacy of IM ketorolac versus that of oral ibuprofen in acute musculoskeletal pain."5.08Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain. ( Paris, PM; Seaberg, DC; Turturro, MA, 1995)
"To examine if wound aetiology has an effect on the pain-relieving properties of an ibuprofen-releasing foam dressing, which was previously shown to reduce pain in wounds of various aetiologies, compared with local best practice (LBP)."3.77Analgesic efficacy of an ibuprofen-releasing foam dressing compared with local best practice for painful exuding wounds. ( Arapoglou, V; Dimakakos, EP; Gjødsbøl, K; Glynn, C; Katsenis, K; Petersen, B; Schäfer, E; Syrigos, KN; Tsoutos, D; Zakopoulou, N, 2011)
"Patientssufferingfromacute trauma (group A (symptoms existent up to 48 hours) as well as patients with chronic symptoms (group B) experienced a fast and prominent improvement of symptoms."2.78[Topical gel formulation of ibuprofen in the treatment of acute and chronic joint and soft tissue pain. Results of a non-interventional observational trial]. ( Petersen-Braun, M; Wegener, T, 2013)
"Eighteen (90%) wounds in the saline-chitosan group and 11 (55%) wounds in the saline-gauze group were healed."1.42Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention. ( Hsu, JR; Noel, SP; Rathbone, CR; Rivera, JC; Wenke, JC, 2015)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's1 (5.00)18.2507
2000's5 (25.00)29.6817
2010's7 (35.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Dogruyol, S1
Kocak, AO1
Akbas, I1
Menekse, TS1
Gur, STA1
Dogruyol, T1
Cakir, Z1
Parri, N1
Lazzeri, S1
Jin, J1
Wang, X1
Wang, J1
Wan, Z1
Kalliomäki, J1
Attal, N1
Jonzon, B1
Bach, FW1
Huizar, K1
Ratcliffe, S1
Eriksson, B1
Janecki, M1
Danilov, A1
Bouhassira, D1
Petersen-Braun, M1
Wegener, T1
Korownyk, C1
Young, J1
Michael Allan, G1
Rivera, JC1
Hsu, JR1
Noel, SP1
Wenke, JC1
Rathbone, CR1
Graudins, A1
Meek, R1
Parkinson, J1
Egerton-Warburton, D1
Meyer, A1
Romanelli, M2
Dini, V1
Polignano, R1
Bonadeo, P1
Maggio, G1
Palao i Domenech, R1
Tsiftsis, DD1
Slonková, V1
Jortikka, A1
Johannesen, N1
Ram, A1
Persson, LM1
Altindas, M1
Orsted, H1
Schäfer, E2
Stanhope, B1
Arapoglou, V1
Katsenis, K1
Syrigos, KN1
Dimakakos, EP1
Zakopoulou, N1
Gjødsbøl, K1
Glynn, C2
Petersen, B1
Tsoutos, D1
Clark, E1
Plint, AC1
Correll, R1
Gaboury, I1
Passi, B1
Price, P1
Fogh, K1
Krasner, DL1
Osterbrink, J1
Sibbald, RG1
Ellman, MH1
Turturro, MA1
Paris, PM1
Seaberg, DC1
Grinëv, MV1
Golubeva, AV1
Zapata-Sirvent, R1
Hansbrough, JF2
Bartle, EJ1
Zapata-Sirvent, RL1
Shackford, SR1
Hoyt, D1
Carter, WH1
Rao, CM1
Kumar, A1
Kulkarni, DR1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
EN20-01: A 24 Week Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Moderate to Severe Knee Osteoarthritis Pain.[NCT05025787]Phase 277 participants (Anticipated)Interventional2021-10-25Recruiting
Phase III Clinical Trial Studying Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children[NCT02477007]Phase 3304 participants (Actual)Interventional2015-12-03Completed
A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy[NCT01267136]Phase 484 participants (Actual)Interventional2011-01-31Completed
Ibuprofen vs. Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?[NCT01605240]50 participants (Anticipated)Interventional2012-07-31Recruiting
A Randomized Double-blinded Trial Comparing the Clinical Efficacy and Pharmacokinetic Parameters of Oral Diclofenac and Intramuscular Diclofenac in Patients With Acute Limb Injuries[NCT03472339]Phase 4300 participants (Anticipated)Interventional2018-01-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Efficacy of Two Different Liquid Pain Medications: Tramadol vs. Codeine/Acetaminophen During the Post-tonsillectomy Recovery Period.

Average number of post-operative days with pain score >4/10. Pain score assessments were administered once daily by parents using either the Numeric Rating Scale (NRS-11) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 8-15 (von Baeyer et al., 2009) or the Faces Pain Scale-Revised (FPS-R) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 4-10 (Hicks et al., 2001). (NCT01267136)
Timeframe: Efficacy was assessed daily during the 10-day postoperative recovery period.

Interventiondays (Median)
Capital® With Codeine Suspension1.5
Tramadol Suspension1

Number of Participants Reporting Side Effects During the Post-tonsillectomy Recovery Period.

Parent-reported side effects entered in 10-day diary. (NCT01267136)
Timeframe: Side effects will be observed and recorded daily by caregivers for a total of 10 days in the take-home diary.

,
Interventionparticipants (Number)
NauseaVomitingFeverItchingRashSweatingDizzinessHeadacheConstipationOversedationTonsil bleed
Capital® With Codeine Suspension202111519151221143
Tramadol Suspension201810121717172180

Reviews

4 reviews available for ibuprofen and Injuries

ArticleYear
Efficacy of ibuprofen in musculoskeletal post-traumatic pain in children: A systematic review.
    PloS one, 2020, Volume: 15, Issue:12

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Female;

2020
Efficacy and safety of ibuprofen in children with musculoskeletal injuries: A systematic review and meta-analysis of randomized controlled trials.
    Medicine, 2021, Jul-02, Volume: 100, Issue:26

    Topics: Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Musculoskeletal Pain; Randomized Controlled Tria

2021
Why combine a foam dressing with ibuprofen for wound pain and moist wound healing?
    International wound journal, 2007, Volume: 4 Suppl 1

    Topics: Administration, Topical; Analgesics, Non-Narcotic; Bandages; Humans; Ibuprofen; Pain; Pain Managemen

2007
[Multiple organ failure].
    Vestnik khirurgii imeni I. I. Grekova, 2001, Volume: 160, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Controlled Clinical Trials

2001

Trials

9 trials available for ibuprofen and Injuries

ArticleYear
Comparison of ibuprofen and piroxicam gel in the treatment of trauma pain: A randomized double-blind trial of geriatric population.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:10

    Topics: Administration, Topical; Aged; Aged, 80 and over; Analgesics; Double-Blind Method; Female; Geriatric

2020
A randomized, double-blind, placebo-controlled trial of a chemokine receptor 2 (CCR2) antagonist in posttraumatic neuralgia.
    Pain, 2013, Volume: 154, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response R

2013
[Topical gel formulation of ibuprofen in the treatment of acute and chronic joint and soft tissue pain. Results of a non-interventional observational trial].
    MMW Fortschritte der Medizin, 2013, Mar-21, Volume: 155 Suppl 1

    Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chr

2013
A randomised controlled trial of paracetamol and ibuprofen with or without codeine or oxycodone as initial analgesia for adults with moderate pain from limb injury.
    Emergency medicine Australasia : EMA, 2016, Volume: 28, Issue:6

    Topics: Acetaminophen; Adult; Aged; Analgesia; Analgesics; Codeine; Double-Blind Method; Drug Therapy, Combi

2016
Ibuprofen slow-release foam dressing reduces wound pain in painful exuding wounds: preliminary findings from an international real-life study.
    The Journal of dermatological treatment, 2009, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Delayed-Action Preparations; Female; Follow-Up Studie

2009
Effect of an ibuprofen-releasing foam dressing on wound pain: a real-life RCT.
    Journal of wound care, 2008, Volume: 17, Issue:8

    Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents, Non-Steroidal; Exudates and Transudates;

2008
Paracetamol/codeine probably had equivalent analgesia to ibuprofen in children with extremity injuries.
    Archives of disease in childhood. Education and practice edition, 2010, Volume: 95, Issue:5

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Co

2010
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain.
    Annals of emergency medicine, 1995, Volume: 26, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal;

1995

Other Studies

7 other studies available for ibuprofen and Injuries

ArticleYear
Optimal pain relief for pediatric MSK injury.
    Canadian family physician Medecin de famille canadien, 2015, Volume: 61, Issue:6

    Topics: Acetaminophen; Analgesics; Canada; Child; Codeine; Drug Combinations; Humans; Ibuprofen; Morphine; M

2015
Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention.
    Clinical and translational science, 2015, Volume: 8, Issue:5

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Prolife

2015
Analgesic efficacy of an ibuprofen-releasing foam dressing compared with local best practice for painful exuding wounds.
    Journal of wound care, 2011, Volume: 20, Issue:7

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; M

2011
Diagnosis and management of bursitis.
    Comprehensive therapy, 1984, Volume: 10, Issue:8

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bursitis; Chondrocalcinosi

1984
Prevention of posttraumatic alterations in lymphocyte subpopulations in mice by immunomodulating drugs.
    Archives of surgery (Chicago, Ill. : 1960), 1986, Volume: 121, Issue:1

    Topics: Animals; Cimetidine; Corticosterone; Cyclophosphamide; Female; Ibuprofen; Leukocyte Count; Lymphocyt

1986
Immunomodulating drugs increase resistance against sepsis in traumatized mice.
    The Journal of trauma, 1986, Volume: 26, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Cimetidine; Cyclophosphamide; Female; Ibuprofen; Immune Tolerance;

1986
Wound healing profile of copper salts of enfenamic acid & ibuprofen.
    The Indian journal of medical research, 1988, Volume: 88

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Copper; Drug Combinations; Drug Interactions; Drug

1988