Page last updated: 2024-10-27

fentanyl and Injuries

fentanyl has been researched along with Injuries in 47 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
"Our aim was to evaluate a nurse-initiated pain-management protocol in adult patients with traumatic injuries in the short and in the long term, utilizing fentanyl for severe pain."7.85Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain. ( Goslings, JC; Hollmann, MW; Lirk, P; Ridderikhof, ML; Schep, NW; Schyns, FJ, 2017)
"The implementation of a fentanyl-based pain management protocol resulted in a marked reduction in time to initial analgesia among trauma patients."7.74A fentanyl-based pain management protocol provides early analgesia for adult trauma patients. ( Curtis, KM; Fanciullo, G; Henriques, HF; Reynolds, CM; Suber, F, 2007)
" Although intravenously administered morphine can readily provide rapid and effective prehospital analgesia, oral transmucosal fentanyl citrate (OTFC) is a safe alternative that does not require intravenous access."5.38Safety and efficacy of oral transmucosal fentanyl citrate for prehospital pain control on the battlefield. ( Fowler, M; Kotwal, RS; McGhee, L; McManus, JG; Pennardt, A; Talbot, TS; Wedmore, IS, 2012)
"Oral transmucosal fentanyl citrate can provide an alternative means of delivering effective, rapid-onset, and noninvasive pain management in an out-of-hospital, combat, or austere environment."5.11A novel pain management strategy for combat casualty care. ( Holcomb, JB; Johnson, TR; Kotwal, RS; Meyer, DE; Mosely, DS; O'Connor, KC, 2004)
"morphine, hydromorphone, fentanyl, trauma, acute pain, intravenous, opioid, pharmacokinetics, and pharmacodynamics."4.93Opioid Pharmacokinetics-Pharmacodynamics: Clinical Implications in Acute Pain Management in Trauma. ( Ensom, MH; MacKenzie, M; Zed, PJ, 2016)
"Our aim was to evaluate a nurse-initiated pain-management protocol in adult patients with traumatic injuries in the short and in the long term, utilizing fentanyl for severe pain."3.85Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain. ( Goslings, JC; Hollmann, MW; Lirk, P; Ridderikhof, ML; Schep, NW; Schyns, FJ, 2017)
"The implementation of a fentanyl-based pain management protocol resulted in a marked reduction in time to initial analgesia among trauma patients."3.74A fentanyl-based pain management protocol provides early analgesia for adult trauma patients. ( Curtis, KM; Fanciullo, G; Henriques, HF; Reynolds, CM; Suber, F, 2007)
"Over an eight-month period, a convenience sample of consenting patients at an urban teaching hospital ED who required sedation for painful procedures were enrolled in a descriptive study of therapeutic propofol sedation."3.69The use of propofol for sedation in the emergency department. ( Mathias, S; Seaberg, DC; Swanson, ER, 1996)
"Using Department of Defense Trauma Registry data for the Afghanistan conflict from 2005 to 2018, we examined 2,402 records of prehospital analgesia administration to assess temporal trends in medication choice and proportions receiving analgesia, including subanalysis of a cohort screened for an indication with minimal contraindication for analgesia."3.01Patterns of Palliation: A Review of Casualties That Received Pain Management Before Reaching Role 2 in Afghanistan. ( Burgess, M; Hinojosa-Laborde, C; Hudson, IL; Newberry, RK; Ryan, KL; Schauer, SG; Staudt, AM; VanFosson, CA, 2023)
" There was no significant difference in the incidence of adverse effects between the two drugs."2.77The effectiveness and adverse events of morphine versus fentanyl on a physician-staffed helicopter. ( Cudnik, M; Emerman, CL; Pakiela, J; Smith, DA; Smith, MD; Wang, Y, 2012)
"In the first trial in trauma patients and largest trial in any surgical population, the (1) BIS was reliable and has advantages over RASS of being continuous and objective, at least during a propofol SAT; (2) BIS interpretation remains somewhat subjective in patients receiving paralytic agents or with traumatic brain injury."2.76Bispectral index to monitor propofol sedation in trauma patients. ( Gomez-Rodriguez, JC; Livingstone, AS; Ogilvie, MP; Pereira, BM; Pierre, EJ; Proctor, KG; Ryan, ML, 2011)
"To determine whether healthy and traumatized dogs receiving a constant rate infusion (CRI) of either morphine or fentanyl have decreased urine production."2.73Effects of morphine and fentanyl constant rate infusion on urine output in healthy and traumatized dogs. ( Anderson, MK; Day, TK, 2008)
"The propofol infusion rate was 11."2.72A comparison of cardiorespiratory variables during isoflurane-fentanyl and propofol-fentanyl anaesthesia for surgery in injured cats. ( Auer, U; Liehmann, L; Mosing, M, 2006)
"The surgical wound hyperalgesia was assessed by measuring pain threshold to pressure on the wound by using an algometer, and also by measuring the intensity of pain to suprathreshold pressure on the wound with the visual analog self-rating method."2.67Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia. ( Bradley, EL; Finger, J; Isakson, A; Kissin, I; Oz, Y; Tverskoy, M, 1994)
" During the second part, the NAL dosage was 2."2.66[Comparative clinical study of nalbuphine and fentanyl. Effects and side effects with special reference to the induction phase]. ( Brandt, L; Duda, D; Müller, H, 1987)
"Early treatment of pain improves outcomes after injury, while inadequate treatment leads to higher rates of post-traumatic stress disorder (PTSD)."1.72Trends in prehospital pain management: two decades of point-of-injury care. ( Avital, G; Bader, T; Benov, A; Chen, J; Fridrich, L; Gelikas, S; Glassberg, E; Nadler, R; Nakar, H; Sorkin, A; Tsur, AM, 2022)
"Acute pain secondary to trauma is commonly encountered on the battlefield."1.48Opioid analgesia on the battlefield: a retrospective review of data from Operation HERRICK. ( Hooper, C; Lewis, P; Wright, C, 2018)
"Ketamine is an N-methyl-d-aspartate (NMDA) receptor antagonist that provides potent analgesia without noticeable respiratory depression."1.43COMPARISON OF INTRAOPERATIVE KETAMINE VS. FENTANYL USE DECREASES POSTOPERATIVE OPIOID REQUIREMENTS IN TRAUMA PATIENTS UNDERGOING CERVICAL SPINE SURGERY. ( Angus, GL; Berkowitz, AC; Ginsburg, AM; Ginsburg, DB; Kang, A; Pesso, RM, 2016)
"Pain associated with pediatric trauma is often under-assessed and under-treated in the out-of-hospital setting."1.39Effect of introducing the mucosal atomization device for fentanyl use in out-of-hospital pediatric trauma patients. ( Kozak, MA; Miramonti, CM; O'Donnell, DP; Schafer, LC; Stevens, AC; Weinstein, E, 2013)
"Patient records of conscious adult trauma victims transported by our air rescue helicopter service over 10 yr were reviewed retrospectively."1.39Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study. ( Albrecht, E; Decosterd, I; Hugli, O; Schoettker, P; Taffe, P; Yersin, B, 2013)
"Emergent adult trauma patients were included with an initial prehospital Glasgow Coma Scale score of ≥13 and systolic blood pressure >90 mm Hg."1.38Safety of prehospital intravenous fentanyl for adult trauma patients. ( Byyny, RL; Colwell, CB; Gravitz, C; Haukoos, JS; Liao, MM; McVaney, KE; Soriya, GC, 2012)
" Although intravenously administered morphine can readily provide rapid and effective prehospital analgesia, oral transmucosal fentanyl citrate (OTFC) is a safe alternative that does not require intravenous access."1.38Safety and efficacy of oral transmucosal fentanyl citrate for prehospital pain control on the battlefield. ( Fowler, M; Kotwal, RS; McGhee, L; McManus, JG; Pennardt, A; Talbot, TS; Wedmore, IS, 2012)
"Relative to healthy controls, both trauma-exposed groups had lower micro-opioid receptor BP2 in extended amygdala, nucleus accumbens, and dorsal frontal and insular cortex but had higher BP2 in the orbitofrontal cortex."1.34Altered central micro-opioid receptor binding after psychological trauma. ( Britton, JC; Bueller, JA; Fig, LM; Koeppe, RA; Liberzon, I; Phan, KL; Taylor, SF; Zubieta, JK, 2007)
"Fentanyl was provided frequently, with good effect and minimal cardiorespiratory consequence."1.33Fentanyl trauma analgesia use in air medical scene transports. ( Biddinger, PD; Harrison, T; Rago, O; Thomas, SH; Wedel, SK, 2005)
"However, if pain is unmanageable in the outpatient department, we believe that options include hospital admission, using the contained method of application or, in the worst case scenario, cessation of treatment."1.33Determining pain levels in patients treated with maggot debridement therapy. ( Budding, T; Oskam, J; Steenvoorde, P, 2005)
"Postfentanyl vital signs were reviewed for evidence of hemodynamic or ventilatory compromise."1.30Prehospital fentanyl analgesia in air-transported pediatric trauma patients. ( DeVellis, P; Stein, JP; Thomas, SH; Vinci, RJ; Wedel, SK, 1998)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19905 (10.64)18.7374
1990's6 (12.77)18.2507
2000's12 (25.53)29.6817
2010's20 (42.55)24.3611
2020's4 (8.51)2.80

Authors

AuthorsStudies
Carenzo, L1
McDonald, A1
Grier, G1
Hudson, IL1
Staudt, AM1
Burgess, M1
Hinojosa-Laborde, C1
Schauer, SG1
Newberry, RK1
Ryan, KL1
VanFosson, CA1
Nakar, H1
Sorkin, A1
Nadler, R1
Tsur, AM1
Gelikas, S1
Avital, G1
Glassberg, E1
Bader, T1
Fridrich, L1
Chen, J1
Benov, A1
Stowell, RD1
Sipe, GO1
Dawes, RP1
Batchelor, HN1
Lordy, KA1
Whitelaw, BS1
Stoessel, MB1
Bidlack, JM1
Brown, E1
Sur, M1
Majewska, AK1
Häske, D1
Böttiger, BW1
Bouillon, B1
Fischer, M1
Gaier, G1
Gliwitzky, B1
Helm, M1
Hilbert-Carius, P1
Hossfeld, B1
Schempf, B1
Wafaisade, A1
Bernhard, M1
Rech, MA1
Barbas, B1
Chaney, W1
Greenhalgh, E1
Turck, C1
Lewis, P1
Wright, C1
Hooper, C1
O'Donnell, DP1
Schafer, LC1
Stevens, AC1
Weinstein, E1
Miramonti, CM1
Kozak, MA1
Butler, FK1
Kotwal, RS3
Buckenmaier, CC1
Edgar, EP1
O'Connor, KC2
Montgomery, HR1
Shackelford, SA1
Gandy, JV1
Wedmore, I1
Timby, JW1
Gross, K1
Bailey, JA1
MacKenzie, M1
Zed, PJ1
Ensom, MH1
Mora, AG1
Ganem, VJ1
Ervin, AT1
Maddry, JK1
Bebarta, VS1
Berkowitz, AC1
Ginsburg, AM1
Pesso, RM1
Angus, GL1
Kang, A1
Ginsburg, DB1
Ridderikhof, ML1
Schyns, FJ1
Schep, NW1
Lirk, P1
Hollmann, MW1
Goslings, JC1
Masoudi Alavi, N1
Aboutalebi, MS1
Sadat, Z1
Anderson, MK1
Day, TK1
Schofield, J1
Johnston, AM1
de Mello, WF1
Shear, ML1
Adler, JN1
Shewakramani, S1
Ilgen, J1
Soremekun, OA1
Nelson, S1
Thomas, SH4
Smith, MD1
Wang, Y1
Cudnik, M1
Smith, DA1
Pakiela, J1
Emerman, CL1
Ogilvie, MP1
Pereira, BM1
Ryan, ML1
Gomez-Rodriguez, JC1
Pierre, EJ1
Livingstone, AS1
Proctor, KG1
Leelanukrom, R1
Suraseranivongse, S1
Boonrukwanich, V1
Wechwinij, S1
Soriya, GC1
McVaney, KE1
Liao, MM1
Haukoos, JS1
Byyny, RL1
Gravitz, C1
Colwell, CB1
Michetti, CP1
Maguire, JF1
Kaushik, A1
Pullarkat, RR1
Boro, TV1
Rizzo, AG1
Seoudi, H1
Meehan, M1
Robinson, L1
Albrecht, E1
Taffe, P1
Yersin, B1
Schoettker, P1
Decosterd, I1
Hugli, O1
Gallagher, R1
Wedmore, IS1
McManus, JG1
Pennardt, A1
Talbot, TS1
Fowler, M1
McGhee, L1
Godambe, SA1
Elliot, V1
Matheny, D1
Pershad, J1
Johnson, TR1
Mosely, DS1
Meyer, DE1
Holcomb, JB1
De Lorenzo, RA1
Bredahl, C1
Futtrup, T1
Jakobsen, A1
Rago, O1
Harrison, T1
Biddinger, PD1
Wedel, SK2
Steenvoorde, P1
Budding, T1
Oskam, J1
Chao, A1
Huang, CH1
Pryor, JP1
Reilly, PM1
Schwab, CW1
Liehmann, L1
Mosing, M1
Auer, U1
Liberzon, I1
Taylor, SF1
Phan, KL1
Britton, JC1
Fig, LM1
Bueller, JA1
Koeppe, RA1
Zubieta, JK1
Curtis, KM1
Henriques, HF1
Fanciullo, G1
Reynolds, CM1
Suber, F1
Newby, DM1
Edbrooke, DL1
Tverskoy, M1
Oz, Y1
Isakson, A1
Finger, J1
Bradley, EL1
Kissin, I1
Yoshida, S1
Hashimoto, M1
Yamasaki, K1
Kaibara, A1
Shirouzu, Y1
Kakegawa, T1
Shirouzu, K1
Swanson, ER1
Seaberg, DC1
Mathias, S1
DeVellis, P1
Stein, JP1
Vinci, RJ1
Prokić, D1
Luger, TJ1
Hill, HF1
Schlager, A1
Buniatian, AA1
Trekova, NA1
Ter-Mikaelian, DK1
Mierbekov, EM1
Asmangulian, ET1
Alazia, M1
Angel, G1
Badetti, C1
Dumont, JC1
François, G1
Duda, D1
Müller, H1
Brandt, L1
Oseev, VV1
Timofeev, VV1
Tsybuliak, GN1
Meshcheriakov, AV1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department[NCT03996564]26 participants (Actual)Interventional2016-02-22Completed
Efficacy and Adverse Events of Morphine and Fentanyl in an Aeromedical Setting[NCT00580489]204 participants (Actual)Interventional2006-08-31Completed
Pain Management in Adults in Primary Intervention of the Mobile Emergency and Resuscitation Service of Pontoise[NCT05791253]365 participants (Actual)Observational2023-03-09Completed
Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl Using Cold Pressor Test (CPT) in Volunteers: A Randomized, Double Blind, Placebo-controlled Crossover Study.[NCT03894800]Phase 412 participants (Actual)Interventional2019-04-23Completed
Comparison of Two Methods Using Intranasal Lidocaine to Alleviate Discomfort Associated With Administration of Intranasal Midazolam in Children.[NCT03054844]Phase 255 participants (Actual)Interventional2017-04-03Completed
A Prospective Randomized Double Blind Evaluation of Ketamine/Propofol vs Ketamine Alone for Pediatric Extremity Fracture Reduction[NCT00490997]Phase 4140 participants (Actual)Interventional2007-06-30Completed
Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions[NCT00596050]Phase 450 participants (Actual)Interventional2006-08-31Completed
Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090]Phase 330 participants (Actual)Interventional2014-07-31Completed
Randomized Controlled Trial of the Use of Intramuscular Fentanyl for the Incision and Drainage of Abscess in the Emergency Department[NCT01881997]Phase 40 participants (Actual)Interventional2011-06-30Withdrawn (stopped due to IRB modifications made study impractical.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Change in Numeric Pain Score (NPS) From First to Last Dose

"Mean difference in the numeric pain score (NPS) from the first dose to the final dose of medication administered.~A significant mean pain score change is defined as greater than or equal to 2~Numeric Pain Score (NPS) 0-10, 0 Least pain, 10 most pain" (NCT00580489)
Timeframe: Medication was administered over a mean transport time of 37 minutes in the Morphine group and 43 minutes in the Fentanyl group.

Interventionscore on a scale (Mean)
Morphine2.2
Fentanyl2.5

Recording of Instance of Narcotic Side Effects.

Instances of narcotic side effects (vital sign derangement, itching, nausea/vomiting) . (NCT00580489)
Timeframe: Groups were observed a mean of 37 minutes in the Morphine Group and a mean of 43 minutes in the Fentanyl group for side effects.

Interventionparticipants (Number)
Arm C Morphine0
Arm D Fentanyl0

Parental Satisfaction

If my child needed medications to stay calm for a procedure, I would like to use these same medications again. (NCT03054844)
Timeframe: 1 minute

InterventionParticipants (Count of Participants)
PREMED10
PREMIX12

Procedural Distress, Cry Duration

Cry duration was measured in seconds and defined as the time from onset of crying following administration of an IN medication until the cessation of crying sounds and/or tears. If a patient did not cry, the cry duration was zero (NCT03054844)
Timeframe: 10 minutes

Interventionseconds (Mean)
PREMED84
PREMIX73

Procedural Distress, FLACC

The Faces, Legs, Activity, Cry, Consolability (FLACC) scale is comprised of five criteria (face, legs, activity, cry, consolability), with a possible score of 0 to 2 units on a scale for each criteria and a possible total score of 0 to 10 units on a scale (0 meaning no pain, 10 meaning most pain). (NCT03054844)
Timeframe: 10 minutes

InterventionUnits on a scale (Mean)
PREMED6.7
PREMIX7

Procedural Distress, OSBD-R

The Observational Scale of Behavioral Distress-Revised (OSBD-R) is an observational measure of pain and distress shown to have strong validity in children. The scale is an 8-factor, weighted observational scale used to measure distress associated with medical procedures, which has been validated in children and adults aged 1 to 20 years. The total Observational Scale of Behavioral Distress-Revised score is the sum of the scale scores for each phase, with each phase assigned a score from 0 to 23.5 units on a scale (0=no distress, 23.5=maximum distress), based on the frequency and types of behaviors observed during a predetermined number of 15-second intervals during each phase. There were four phases so the range of scores for the total OSBD-R was 0 to 94 units on a scale, with a higher score indicated a greater degree of distress. (NCT03054844)
Timeframe: 10 minutes

InterventionUnits on a scale (Mean)
PREMED6.4
PREMIX7

Procedural Pain

The Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) utilizes six observational factors (cry, facial, verbal, torso, touch, and legs) to evaluate pain in young children and can be used to monitor the effectiveness of interventions for reducing the pain and discomfort of an intervention. This scale rates each behavior numerically, with a score of 4-6 units on a scale representing no pain, and a maximum score of 13 units on a scale representing (most pain perceived). (NCT03054844)
Timeframe: 10 minutes

InterventionUnits on a scale (Mean)
PREMED10.6
PREMIX10.5

Provider Satisfaction

I would like to use this method of administering intranasal midazolam and lidocaine again in the future (NCT03054844)
Timeframe: 1 minute

InterventionParticipants (Count of Participants)
PREMED8
PREMIX24

Reviews

4 reviews available for fentanyl and Injuries

ArticleYear
Patterns of Palliation: A Review of Casualties That Received Pain Management Before Reaching Role 2 in Afghanistan.
    Military medicine, 2023, 01-04, Volume: 188, Issue:1-2

    Topics: Adult; Afghan Campaign 2001-; Afghanistan; Emergency Medical Services; Fentanyl; Humans; Ketamine; M

2023
When to Pick the Nose: Out-of-Hospital and Emergency Department Intranasal Administration of Medications.
    Annals of emergency medicine, 2017, Volume: 70, Issue:2

    Topics: Administration, Intranasal; Analgesics, Opioid; Conscious Sedation; Dexmedetomidine; Drug Overdose;

2017
Opioid Pharmacokinetics-Pharmacodynamics: Clinical Implications in Acute Pain Management in Trauma.
    The Annals of pharmacotherapy, 2016, Volume: 50, Issue:3

    Topics: Analgesics, Opioid; Fentanyl; Humans; Hydromorphone; Morphine; Pain; Pain Management; Pain Measureme

2016
The management of wound-related procedural pain (volitional incident pain) in advanced illness.
    Current opinion in supportive and palliative care, 2013, Volume: 7, Issue:1

    Topics: Administration, Buccal; Administration, Intranasal; Analgesics, Opioid; Breakthrough Pain; Cognition

2013

Trials

10 trials available for fentanyl and Injuries

ArticleYear
Effects of morphine and fentanyl constant rate infusion on urine output in healthy and traumatized dogs.
    Veterinary anaesthesia and analgesia, 2008, Volume: 35, Issue:6

    Topics: Analgesics, Opioid; Animals; Dogs; Female; Fentanyl; Kidney; Kidney Function Tests; Male; Morphine;

2008
Transbuccal fentanyl for rapid relief of orthopedic pain in the ED.
    The American journal of emergency medicine, 2010, Volume: 28, Issue:8

    Topics: Administration, Buccal; Administration, Oral; Adult; Analgesics, Opioid; Double-Blind Method; Emerge

2010
The effectiveness and adverse events of morphine versus fentanyl on a physician-staffed helicopter.
    The Journal of emergency medicine, 2012, Volume: 43, Issue:1

    Topics: Adult; Air Ambulances; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; Male; Morp

2012
Bispectral index to monitor propofol sedation in trauma patients.
    The Journal of trauma, 2011, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Analysis of Variance; Atracurium; Co

2011
Effect of wound infiltration with bupivacaine on postoperative analgesia in neonates and infants undergoing major abdominal surgery: a pilot randomized controlled trial.
    Journal of anesthesia, 2012, Volume: 26, Issue:4

    Topics: Abdomen; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Fentanyl; Humans; Infant; Infant, Newb

2012
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
    Pediatrics, 2003, Volume: 112, Issue:1 Pt 1

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S

2003
A novel pain management strategy for combat casualty care.
    Annals of emergency medicine, 2004, Volume: 44, Issue:2

    Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Iraq; Military Personnel; Pain; Pain Mea

2004
A comparison of cardiorespiratory variables during isoflurane-fentanyl and propofol-fentanyl anaesthesia for surgery in injured cats.
    Veterinary anaesthesia and analgesia, 2006, Volume: 33, Issue:3

    Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Blood Chemical Analys

2006
Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:2

    Topics: Adult; Analgesia; Double-Blind Method; Female; Fentanyl; Humans; Hyperalgesia; Ketamine; Middle Aged

1994
[Comparative clinical study of nalbuphine and fentanyl. Effects and side effects with special reference to the induction phase].
    Der Anaesthesist, 1987, Volume: 36, Issue:8

    Topics: Adult; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Pressure; Clinica

1987

Other Studies

33 other studies available for fentanyl and Injuries

ArticleYear
Pre-hospital oral transmucosal fentanyl citrate for trauma analgesia: preliminary experience and implications for civilian mass casualty response.
    British journal of anaesthesia, 2022, Volume: 128, Issue:2

    Topics: Administration, Oral; Adult; Analgesia; Analgesics, Opioid; Emergency Medical Services; Female; Fent

2022
Trends in prehospital pain management: two decades of point-of-injury care.
    The Israel Medical Association journal : IMAJ, 2022, Volume: 24, Issue:9

    Topics: Adult; Analgesics; Emergency Medical Services; Female; Fentanyl; Humans; Male; Military Personnel; M

2022
Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex.
    Nature neuroscience, 2019, Volume: 22, Issue:11

    Topics: Animals; Benzylamines; Cell Movement; Circadian Rhythm; Clenbuterol; CX3C Chemokine Receptor 1; Dexm

2019
[Analgesia for trauma patients in emergency medicine].
    Der Anaesthesist, 2020, Volume: 69, Issue:2

    Topics: Analgesia; Emergency Medical Services; Emergency Medicine; Fentanyl; Humans; Ketamine; Pain; Pain Ma

2020
Opioid analgesia on the battlefield: a retrospective review of data from Operation HERRICK.
    Journal of the Royal Army Medical Corps, 2018, Volume: 164, Issue:5

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Afghanistan; Analgesics, Opioid; Child; Child, Preschool;

2018
Effect of introducing the mucosal atomization device for fentanyl use in out-of-hospital pediatric trauma patients.
    Prehospital and disaster medicine, 2013, Volume: 28, Issue:5

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Emergency Medic

2013
A Triple-Option Analgesia Plan for Tactical Combat Casualty Care: TCCC Guidelines Change 13-04.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2014,Spring, Volume: 14, Issue:1

    Topics: Acetaminophen; Administration, Buccal; Analgesia; Analgesics; Analgesics, Opioid; Fentanyl; Humans;

2014
En Route Use of Analgesics in Nonintubated, Critically Ill Patients Transported by U.S. Air Force Critical Care Air Transport Teams.
    Military medicine, 2016, Volume: 181, Issue:5 Suppl

    Topics: Adult; Aerospace Medicine; Afghan Campaign 2001-; Air Ambulances; Analgesics; Critical Care; Critica

2016
COMPARISON OF INTRAOPERATIVE KETAMINE VS. FENTANYL USE DECREASES POSTOPERATIVE OPIOID REQUIREMENTS IN TRAUMA PATIENTS UNDERGOING CERVICAL SPINE SURGERY.
    Middle East journal of anaesthesiology, 2016, Volume: 23, Issue:4

    Topics: Adult; Analgesics, Opioid; Cervical Vertebrae; Female; Fentanyl; Humans; Intraoperative Period; Keta

2016
Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Emergency Service, Hospital; Female; Fentany

2017
Pain management of trauma patients in the emergency department: a study in a public hospital in Iran.
    International emergency nursing, 2017, Volume: 33

    Topics: Acetaminophen; Adult; Analgesics; Emergency Service, Hospital; Female; Fentanyl; Hospitals, Public;

2017
Morphine after combat injury and post-traumatic stress disorder.
    The New England journal of medicine, 2010, Apr-08, Volume: 362, Issue:14

    Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Fentanyl; Humans; Iraq War, 2003-2011; Ketamine; Mid

2010
Safety of prehospital intravenous fentanyl for adult trauma patients.
    The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:3

    Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; Follow-Up Studies; Hu

2012
Single-drug sedation with fentanyl for prehospital postintubation sedation in trauma patients.
    The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:4

    Topics: Adult; Benzodiazepines; Brain Injuries; Conscious Sedation; Emergency Medical Services; Female; Fent

2012
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
    British journal of anaesthesia, 2013, Volume: 110, Issue:1

    Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme

2013
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
    British journal of anaesthesia, 2013, Volume: 110, Issue:1

    Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme

2013
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
    British journal of anaesthesia, 2013, Volume: 110, Issue:1

    Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme

2013
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
    British journal of anaesthesia, 2013, Volume: 110, Issue:1

    Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme

2013
Safety and efficacy of oral transmucosal fentanyl citrate for prehospital pain control on the battlefield.
    The journal of trauma and acute care surgery, 2012, Volume: 73, Issue:6 Suppl 5

    Topics: Administration, Mucosal; Administration, Oral; Afghanistan; Analgesics, Opioid; Analysis of Variance

2012
Emergency medicine research on the front lines.
    Annals of emergency medicine, 2004, Volume: 44, Issue:2

    Topics: Analgesics, Opioid; Biomedical Research; Emergency Medicine; Fentanyl; Humans; Military Personnel; P

2004
[Oral transmucosal fentanyl: suitable as an analgesic for children in emergency departments].
    Ugeskrift for laeger, 2005, May-23, Volume: 167, Issue:21

    Topics: Administration, Oral; Analgesics, Opioid; Child; Child, Preschool; Emergency Service, Hospital; Fema

2005
Fentanyl trauma analgesia use in air medical scene transports.
    The Journal of emergency medicine, 2005, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Air Ambulances; Analgesia; Analgesics, Opioid; Child; Ch

2005
Determining pain levels in patients treated with maggot debridement therapy.
    Journal of wound care, 2005, Volume: 14, Issue:10

    Topics: Acetaminophen; Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic;

2005
Analgesic use in intubated patients during acute resuscitation.
    The Journal of trauma, 2006, Volume: 60, Issue:3

    Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Blood Pressure; Cohort Studies; Dose-Response Relati

2006
Altered central micro-opioid receptor binding after psychological trauma.
    Biological psychiatry, 2007, May-01, Volume: 61, Issue:9

    Topics: Adaptation, Physiological; Adult; Amygdala; Analgesics, Opioid; Cerebral Cortex; Fentanyl; Functiona

2007
Fentanyl in the prehospital setting.
    The American journal of emergency medicine, 2007, Volume: 25, Issue:7

    Topics: Administration, Intranasal; Analgesics, Opioid; Emergency Medical Services; Fentanyl; Humans; Pain;

2007
A fentanyl-based pain management protocol provides early analgesia for adult trauma patients.
    The Journal of trauma, 2007, Volume: 63, Issue:4

    Topics: Adult; Analgesia; Analgesics, Opioid; Clinical Protocols; Dose-Response Relationship, Drug; Female;

2007
Influence of sedation on mortality in trauma patients.
    Lancet (London, England), 1983, Jun-18, Volume: 1, Issue:8338

    Topics: Drug Therapy, Combination; Etomidate; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Unit

1983
Effect of fentanyl citrate analgesia on glucose production following trauma in rats.
    The Journal of surgical research, 1996, Volume: 61, Issue:2

    Topics: Analgesia; Analgesics, Opioid; Animals; Catecholamines; Corticosterone; Fentanyl; Glucagon; Glucose;

1996
The use of propofol for sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1996, Volume: 3, Issue:3

    Topics: Adult; Aged; Analgesia; Anesthetics, Intravenous; Conscious Sedation; Emergency Service, Hospital; F

1996
Prehospital fentanyl analgesia in air-transported pediatric trauma patients.
    Pediatric emergency care, 1998, Volume: 14, Issue:5

    Topics: Adolescent; Air Ambulances; Analgesia; Analgesics, Opioid; Boston; Child; Child, Preschool; Clinical

1998
[Choice of anesthesia in persons with multiple injuries].
    Acta chirurgica Iugoslavica, 1975, Volume: 22, Issue:1 Suppl

    Topics: Adolescent; Adult; Droperidol; Fentanyl; Halothane; Humans; Neuroleptanalgesia; Wounds and Injuries

1975
Can midazolam diminish sufentanil analgesia in patients with major trauma? A retrospective study with 43 patients.
    Drug metabolism and drug interactions, 1992, Volume: 10, Issue:1-2

    Topics: Adult; Analgesics; Fentanyl; Humans; Midazolam; Pain; Retrospective Studies; Sufentanil; Wounds and

1992
[Use of an opioid antagonist naloxone and the agonist-antagonist nalbuphine during the awakening period to eliminate depressive effects of fentanyl].
    Vestnik Akademii meditsinskikh nauk SSSR, 1991, Issue:7

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Child; Child, Preschool; D

1991
[The effect of stopping morphine sedation on the production of gastric juice in patients resuscitated with artificial respiration].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8 Suppl

    Topics: Anesthesia; Fentanyl; Gastric Juice; Humans; Hypnotics and Sedatives; Morphine; Respiration, Artific

1989
[Initial experience in neuroleptoanalgesia in the surgery of injuries].
    Vestnik khirurgii imeni I. I. Grekova, 1968, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Amputation, Surgical; Arm Injuries; Benperidol; Female; Fentanyl; Fractures, Bone

1968