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diclofenac and Injuries

diclofenac has been researched along with Injuries in 15 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
" The goal of this study was to determine the impact of administration of the non-selective NSAID diclofenac in the inflammatory phase of bone repair in mice with or without lipopolysaccharide-induced systemic inflammation."7.91Defective bone repair in diclofenac treated C57Bl6 mice with and without lipopolysaccharide induced systemic inflammation. ( Abou-Rjeili, M; Akoury, E; Al-Saran, Y; Awlia, A; Chan, D; Henderson, JE; Lemarié, CA; Martineau, PA; Ouellet, S; Ramirez-Garcia-Luna, JL; Wong, TH, 2019)
"There was no statistical difference in the mean reduction in pain score between any of the combinations at any point, although combination therapy was the first to reach a clinically significant reduction in pain score (<13 mm), and diclofenac-paracetamol combinations consistently produced a greater reduction in mean pain score than either nonsteroidal antiinflammatory drugs or paracetamol alone."5.11Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury. ( Lam, PK; Man, SY; Rainer, TH; Woo, WW, 2005)
" In clinical conditions marked by acute or chronic pain and inflammation, such as oral surgery, dysmenorrhea, low back pain, renal colic, and biliary colic, as well as in post-traumatic and postoperative conditions, diclofenac sodium, a nonsteroidal anti-inflammatory drug with potent prostaglandin synthetase inhibition, has been shown to be an effective analgesic agent."5.06Use of diclofenac in analgesia. ( Kantor, TG, 1986)
" The goal of this study was to determine the impact of administration of the non-selective NSAID diclofenac in the inflammatory phase of bone repair in mice with or without lipopolysaccharide-induced systemic inflammation."3.91Defective bone repair in diclofenac treated C57Bl6 mice with and without lipopolysaccharide induced systemic inflammation. ( Abou-Rjeili, M; Akoury, E; Al-Saran, Y; Awlia, A; Chan, D; Henderson, JE; Lemarié, CA; Martineau, PA; Ouellet, S; Ramirez-Garcia-Luna, JL; Wong, TH, 2019)
"Pain treatment with acetaminophen was not inferior to that with diclofenac or the combination of acetaminophen and diclofenac in acute minor musculoskeletal extremity trauma, both in rest and with movement."2.87Acetaminophen or Nonsteroidal Anti-Inflammatory Drugs in Acute Musculoskeletal Trauma: A Multicenter, Double-Blind, Randomized, Clinical Trial. ( Goddijn, H; Goslings, JC; Hollmann, MW; Kemper, EM; Lirk, P; Ridderikhof, ML; Schinkel, E; Van Dieren, S; Vandewalle, E, 2018)
" In a single dose-toxicity study, two adult Cape Griffon Vultures with severe injuries, that were considered to have a very poor prognostic outcome, were dosed intravenously with diclofenac at 0."1.35Veterinary diclofenac threatens Africa's endangered vulture species. ( Cuthbert, R; Duncan, N; Naidoo, V; Wolter, K, 2009)
"Treatment of traumatic corneal abrasion with a contact lens associated with topical NSAID drops sufficiently reduced the pain to allow 80."1.31[Treatment of traumatic corneal abrasion with contact lens associated with topical nonsteroid anti-inflammatory agent (NSAID) and antibiotic: a safe, effective and comfortable solution]. ( Caspers-Valu, LE; Dumont, P; Vandorselaer, T; Vauthier, L; Youssfi, H, 2001)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's1 (6.67)18.2507
2000's4 (26.67)29.6817
2010's6 (40.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Kharaghani, D1
Gitigard, P1
Ohtani, H1
Kim, KO1
Ullah, S1
Saito, Y1
Khan, MQ1
Kim, IS1
Dos Santos Haupenthal, DP1
Zortea, D1
Zaccaron, RP1
de Bem Silveira, G1
Corrêa, MEAB1
Mendes, C1
de Roch Casagrande, L1
Duarte, MB1
Pinho, RA1
Feuser, PE1
Machado-de-Ávila, RA1
Silveira, PCL1
Ridderikhof, ML1
Lirk, P1
Goddijn, H1
Vandewalle, E1
Schinkel, E1
Van Dieren, S1
Kemper, EM1
Hollmann, MW1
Goslings, JC1
Ramirez-Garcia-Luna, JL1
Wong, TH1
Chan, D1
Al-Saran, Y1
Awlia, A1
Abou-Rjeili, M1
Ouellet, S1
Akoury, E1
Lemarié, CA1
Henderson, JE1
Martineau, PA1
Li, C1
Frangione, V1
Rovati, S1
Zheng, Q1
Naidoo, V1
Wolter, K1
Cuthbert, R1
Duncan, N1
Boateng, JS1
Pawar, HV1
Tetteh, J1
van der Vijver, RJ1
van Laarhoven, CJ1
Lomme, RM1
Hendriks, T1
Woo, WW1
Man, SY1
Lam, PK1
Rainer, TH1
Gøtzsche, PC1
Vandorselaer, T1
Youssfi, H1
Caspers-Valu, LE1
Dumont, P1
Vauthier, L1
Dewijze, M1
Jajić, I1
Kantor, TG1
Kral, JG1

Trials

5 trials available for diclofenac and Injuries

ArticleYear
Acetaminophen or Nonsteroidal Anti-Inflammatory Drugs in Acute Musculoskeletal Trauma: A Multicenter, Double-Blind, Randomized, Clinical Trial.
    Annals of emergency medicine, 2018, Volume: 71, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2018
Diclofenac epolamine medicated plaster in the treatment of minor soft tissue injuries: a multicenter randomized controlled trial.
    Current medical research and opinion, 2013, Volume: 29, Issue:9

    Topics: Administration, Topical; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroida

2013
Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury.
    Annals of emergency medicine, 2005, Volume: 46, Issue:4

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dizziness; Female; Humans

2005
[Multicenter open trial of Voltaren gel in patients with rheumatism and traumatic tissue inflammation].
    Reumatizam, 1990, Volume: 37, Issue:1-6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Diclofenac; Female; Gels; Human

1990
Use of diclofenac in analgesia.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Analgesia; Back Pain; Biliary Tract Diseases; Clinical Trials as Topic; Colic; Diclofenac; Double-Bl

1986

Other Studies

10 other studies available for diclofenac and Injuries

ArticleYear
Design and characterization of dual drug delivery based on in-situ assembled PVA/PAN core-shell nanofibers for wound dressing application.
    Scientific reports, 2019, 09-02, Volume: 9, Issue:1

    Topics: Acrylic Resins; Bandages; Cell Adhesion; Cell Death; Cross-Linking Reagents; Diclofenac; Drug Delive

2019
Effects of phonophoresis with diclofenac linked gold nanoparticles in model of traumatic muscle injury.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 110

    Topics: Animals; Catalase; Diclofenac; Disease Models, Animal; Glutathione; Gold; Hyperalgesia; Metal Nanopa

2020
Defective bone repair in diclofenac treated C57Bl6 mice with and without lipopolysaccharide induced systemic inflammation.
    Journal of cellular physiology, 2019, Volume: 234, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Endothelial Cells; Humans; Inflammatio

2019
Veterinary diclofenac threatens Africa's endangered vulture species.
    Regulatory toxicology and pharmacology : RTP, 2009, Volume: 53, Issue:3

    Topics: Africa; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bird Diseases; Diclofenac; Endangered Spec

2009
Polyox and carrageenan based composite film dressing containing anti-microbial and anti-inflammatory drugs for effective wound healing.
    International journal of pharmaceutics, 2013, Jan-30, Volume: 441, Issue:1-2

    Topics: Adhesiveness; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections;

2013
Diclofenac causes more leakage than naproxen in anastomoses in the small intestine of the rat.
    International journal of colorectal disease, 2013, Volume: 28, Issue:9

    Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Body Weight; Diclofenac; Hydroxyproline; Ileum; In

2013
[Paracetamol has the same effect as non-steroidal anti-inflammatory agents in acute musculoskeletal injuries].
    Ugeskrift for laeger, 2006, May-15, Volume: 168, Issue:20

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans

2006
[Treatment of traumatic corneal abrasion with contact lens associated with topical nonsteroid anti-inflammatory agent (NSAID) and antibiotic: a safe, effective and comfortable solution].
    Journal francais d'ophtalmologie, 2001, Volume: 24, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Contact Len

2001
[Voltaren in traumatology].
    Bruxelles medical, 1977, Volume: 57, Issue:9

    Topics: Accidents; Adolescent; Adult; Diclofenac; Drug Evaluation; Female; Humans; Male; Middle Aged; Phenyl

1977
Analgesic effects of prostaglandin synthesis inhibition by diclofenac sodium.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biliary Tract Diseases; Colic; Diclofenac; Humans; Kidney D

1985