Page last updated: 2024-11-02

pentoxifylline and Injuries

pentoxifylline has been researched along with Injuries in 12 studies

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
"Although pentoxifylline produces various beneficial effects in a preheparinized model of hemorrhagic shock, it was unknown whether this agent restores the depressed cardiac output (CO) and tissue perfusion in a nonheparinized model of trauma-hemorrhage and resuscitation and, if so, whether it decreases the susceptibility to sepsis after hemorrhage."7.68Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis. ( Ba, ZF; Chaudry, IH; Tait, SM; Wang, P; Zhou, M, 1993)
"The purpose of this study was to determine whether pentoxifylline administration restores the depressed hepatocellular function after trauma hemorrhage and crystalloid resuscitation and, if so, whether this is the result of the down-regulation of inflammatory cytokines, tumor necrosis factor (TNF) and interleukin-6 (IL-6)."7.68Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation. ( Ayala, A; Ba, ZF; Chaudry, IH; Morrison, MH; Wang, P, 1992)
"Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation."5.30Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998)
"Although pentoxifylline produces various beneficial effects in a preheparinized model of hemorrhagic shock, it was unknown whether this agent restores the depressed cardiac output (CO) and tissue perfusion in a nonheparinized model of trauma-hemorrhage and resuscitation and, if so, whether it decreases the susceptibility to sepsis after hemorrhage."3.68Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis. ( Ba, ZF; Chaudry, IH; Tait, SM; Wang, P; Zhou, M, 1993)
"The purpose of this study was to determine whether pentoxifylline administration restores the depressed hepatocellular function after trauma hemorrhage and crystalloid resuscitation and, if so, whether this is the result of the down-regulation of inflammatory cytokines, tumor necrosis factor (TNF) and interleukin-6 (IL-6)."3.68Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation. ( Ayala, A; Ba, ZF; Chaudry, IH; Morrison, MH; Wang, P, 1992)
"Six patients with post-traumatic impairment who were treated with systemic pentoxifylline were included."2.94Short-Course Pentoxifylline Is Not Effective in Post-Traumatic Smell Loss: A Pilot Study. ( Gudziol, V; Hummel, T; Whitcroft, KL, 2020)
"No means exist for predicting the acute respiratory distress syndrome (ARDS), which complicates sepsis, trauma, and a variety of clinical disorders."2.68An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome. ( Abraham, E; Bianco, JA; Bursten, SL; Federighi, DA; Harris, WE; Moore, EE; Moore, FA; Parsons, P; Repine, JE; Singer, JW, 1996)
"Consecutive patients (n = 60) with trauma or sepsis secondary to major (nontrauma) surgery."2.68Influence of long-term continuous intravenous administration of pentoxifylline on endothelial-related coagulation in critically ill patients. ( Boldt, J; Hempelmann, G; Heyn, S; Müller, M; Welters, I, 1996)
"Major trauma and consecutively associated infectious complications have a major impact on the mechanisms of the specific immune response and the nonspecific inflammatory reaction."2.39[Immune mechanisms of post-traumatic hyperinflammation and sepsis]. ( Baue, AE; Faist, E; Hartl, WH, 1994)
"Both patients experienced unilateral sudden deafness after performing a headfirst pike-type dive into a swimming pool."1.32Persistent inner ear injury after diving. ( Keck, T; Rozsasi, A; Sigg, O, 2003)
"Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation."1.30Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (75.00)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Whitcroft, KL1
Gudziol, V1
Hummel, T1
Rozsasi, A1
Sigg, O1
Keck, T1
Wang, P5
Ba, ZF3
Stepp, KJ1
Chaudry, IH5
Faist, E1
Hartl, WH1
Baue, AE1
Zhou, M1
Tait, SM1
Bursten, SL1
Federighi, DA1
Parsons, P1
Harris, WE1
Abraham, E1
Moore, EE1
Moore, FA1
Bianco, JA1
Singer, JW1
Repine, JE1
Boldt, J2
Müller, M1
Heyn, S1
Welters, I1
Hempelmann, G2
Heesen, M1
Padberg, W1
Martin, K1
Wang, W1
Jarrar, D1
Grinëv, MV1
Golubeva, AV1
Morrison, MH1
Ayala, A1

Reviews

3 reviews available for pentoxifylline and Injuries

ArticleYear
[Immune mechanisms of post-traumatic hyperinflammation and sepsis].
    Immunitat und Infektion, 1994, Volume: 22, Issue:6

    Topics: Colony-Stimulating Factors; Glucans; Humans; Immunologic Factors; Immunotherapy; Interferon-gamma; L

1994
Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (Review).
    International journal of molecular medicine, 1999, Volume: 4, Issue:6

    Topics: Adenosine Triphosphate; Animals; Coloring Agents; Critical Care; Cytokines; Diltiazem; Disease Model

1999
[Multiple organ failure].
    Vestnik khirurgii imeni I. I. Grekova, 2001, Volume: 160, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Controlled Clinical Trials

2001

Trials

4 trials available for pentoxifylline and Injuries

ArticleYear
Short-Course Pentoxifylline Is Not Effective in Post-Traumatic Smell Loss: A Pilot Study.
    Ear, nose, & throat journal, 2020, Volume: 99, Issue:1

    Topics: Adult; Female; Humans; Male; Olfaction Disorders; Pentoxifylline; Phosphodiesterase Inhibitors; Pilo

2020
An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome.
    Critical care medicine, 1996, Volume: 24, Issue:7

    Topics: Adult; Double-Blind Method; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Female; Humans; Ma

1996
Influence of long-term continuous intravenous administration of pentoxifylline on endothelial-related coagulation in critically ill patients.
    Critical care medicine, 1996, Volume: 24, Issue:6

    Topics: Adult; Aged; APACHE; Blood Coagulation; Endothelium, Vascular; Female; Hemodynamics; Humans; Infusio

1996
The influence of volume therapy and pentoxifylline infusion on circulating adhesion molecules in trauma patients.
    Anaesthesia, 1996, Volume: 51, Issue:6

    Topics: Adult; Cell Adhesion Molecules; E-Selectin; Female; Humans; Hydroxyethyl Starch Derivatives; Interce

1996

Other Studies

5 other studies available for pentoxifylline and Injuries

ArticleYear
Persistent inner ear injury after diving.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2003, Volume: 24, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents; Audiometry, Pure-Tone; Bone Conduction; Child; Diving; Electro

2003
Pentoxifylline attenuates the depressed endothelial cell function and vascular muscle contractility following trauma and hemorrhagic shock.
    The Journal of trauma, 1995, Volume: 39, Issue:1

    Topics: Animals; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; No

1995
Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis.
    Surgery, 1993, Volume: 114, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bacterial Infections; Blood Pressure; Ca

1993
Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock.
    Critical care medicine, 1998, Volume: 26, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase; Animal Feed; Animals; Disease Models, Animal; Fatty A

1998
Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation.
    Surgery, 1992, Volume: 112, Issue:2

    Topics: Animals; Blood Pressure; Hemorrhage; Infusions, Intravenous; Interleukin-6; Liver; Male; Pentoxifyll

1992