aminocaproic acid has been researched along with Injuries in 7 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tranexamic acid safely reduces mortality in bleeding trauma patients without increasing the risk of adverse events." | 4.88 | Antifibrinolytic drugs for acute traumatic injury. ( Coats, T; Ker, K; Roberts, I; Shakur, H, 2012) |
| " This series of studies tested whether these drugs (aprotinin, desmopressin, tranexamic acid, epsilon-aminocaproic acid) could reduce bleeding due to traumatic injuries in two models of uncontrolled hemorrhage in rats." | 3.73 | Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhage. ( Cortez, DS; Dick, EJ; Pusateri, AE; Ryan, KL, 2006) |
| "Uncontrolled bleeding is an important cause of death in trauma victims." | 2.52 | Antifibrinolytic drugs for acute traumatic injury. ( Coats, TJ; Ker, K; Roberts, I; Shakur, H, 2015) |
| "The aim of the study was to create a trauma coagulopathy model (TCM) with a hyperfibrinolysis thrombelastography (TEG) pattern similar to injured patients and test the effects of different resuscitation fluids and antifibrinolytics on fibrinolysis." | 1.39 | Influence of resuscitation fluids, fresh frozen plasma and antifibrinolytics on fibrinolysis in a thrombelastography-based, in-vitro, whole-blood model. ( Cotton, BA; Holcomb, JB; Kostousov, V; Matijevic, N; Wade, CE; Wang, YW, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kostousov, V | 1 |
| Wang, YW | 1 |
| Cotton, BA | 1 |
| Wade, CE | 1 |
| Holcomb, JB | 1 |
| Matijevic, N | 1 |
| Roberts, I | 2 |
| Shakur, H | 2 |
| Ker, K | 2 |
| Coats, T | 1 |
| Ortmann, E | 1 |
| Besser, MW | 1 |
| Klein, AA | 1 |
| Coats, TJ | 1 |
| LECHTENBERG, HW | 1 |
| SHARP, AA | 1 |
| Ryan, KL | 1 |
| Cortez, DS | 1 |
| Dick, EJ | 1 |
| Pusateri, AE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Minimum Concentration of Tranexamic Acid Required to Inhibit Fibrinolysis in a Population of Pregnant Women at Term.[NCT02579941] | 40 participants (Actual) | Interventional | 2015-11-30 | Completed | |||
| Prophylactic Use of Topical Tranexamic Acid to Aid Surgical Haemostasis During Caesarean Sections in Parturients With Moderate to High Risk of Bleeding[NCT02492087] | Phase 3 | 84 participants (Anticipated) | Interventional | 2015-08-31 | Recruiting | ||
| Pilot RCT: Use of Tranexamic Acid (TXA) in Post Mastectomy Patients for Seroma and Hematoma Prevention[NCT03738527] | Phase 4 | 100 participants (Anticipated) | Interventional | 2019-10-07 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aminocaproic acid and Injuries
| Article | Year |
|---|---|
Antifibrinolytic drugs for acute traumatic injury.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemo | 2012 |
Antifibrinolytic agents in current anaesthetic practice.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced | 2013 |
Antifibrinolytic agents in current anaesthetic practice.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced | 2013 |
Antifibrinolytic agents in current anaesthetic practice.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced | 2013 |
Antifibrinolytic agents in current anaesthetic practice.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced | 2013 |
Antifibrinolytic drugs for acute traumatic injury.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemo | 2015 |
PATHOLOGICAL FIBRINOLYSIS.
Topics: Aminocaproates; Aminocaproic Acid; Anticoagulants; Blood Coagulation Disorders; Blood Group Incompat | 1964 |
3 other studies available for aminocaproic acid and Injuries
| Article | Year |
|---|---|
Influence of resuscitation fluids, fresh frozen plasma and antifibrinolytics on fibrinolysis in a thrombelastography-based, in-vitro, whole-blood model.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation Disorders; Colloids; Crystalloid Solut | 2013 |
[THE USE OF EPSILON-AMINOCAPROIC ACID IN SURGICAL DISEASES].
Topics: Aminocaproates; Aminocaproic Acid; Hemorrhage; Hemostasis; Humans; Male; Postoperative Complications | 1964 |
Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhage.
Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Aprotinin; Deamino Arginine Vasopressin; Diseas | 2006 |