Page last updated: 2024-10-23

aspirin and Injuries

aspirin has been researched along with Injuries in 59 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
"In the clinical trial of diaspirin cross-linked hemoglobin (DCLHb), optimal therapy required the immediate enrollment of patients with severe, uncompensated, traumatic hemorrhagic shock."9.09The informed consent process and the use of the exception to informed consent in the clinical trial of diaspirin cross-linked hemoglobin (DCLHb) in severe traumatic hemorrhagic shock. DCLHb Traumatic Hemorrhagic Shock study group. ( Cipolle, M; Gens, D; Houghton, J; Koenigsberg, M; Mallory, MN; Rodman, G; Runge, J; Sloan, EP, 1999)
"A double-blind, non-crossover, randomized trial was carried out in 50 patients suffering from pain following trauma to compare the therapeutic effectiveness and tolerance of 200 mg tiaprofenic acid and 600 mg aspirin given 3-times daily for 7 days."9.05A comparative trial of tiaprofenic acid ('Surgam') versus aspirin in the control of pain following injury. ( Cutting, CJ; Thornton, EJ, 1981)
"The efficacy and safety of fenoprofen calcium (Nalfon, Dista, Indianapolis, IN) and aspirin for treating acute inflammatory soft tissue injuries were compared in a 3 to 10-day randomized, double-blind, parallel study of 100 patients with bruise (1), bursitis (33), ligamentous strain (8), myofascitis (43), and tendinitis (15)."9.05Fenoprofen calcium versus aspirin in the treatment of acute inflammatory soft-tissue injuries. ( McIlwain, HH, 1985)
"Diaspirin cross-linked hemoglobin (DCLHb) has demonstrated a pressor effect that could adversely affect traumatic hemorrhagic shock patients through diminished perfusion to vital organs, causing base deficit (BD) and lactate abnormalities."7.76Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation. ( Gao, W; Koenigsberg, MD; Philbin, NB; Sloan, EP, 2010)
" This large, multicenter, randomized clinical trial was designed to compare the addition of diaspirin cross-linked hemoglobin (DCLHb) with standard care in the initial resuscitation of adults experiencing severe, uncompensated, traumatic hemorrhagic shock."7.71Monitoring a clinical trial conducted under the Food and Drug Administration regulations allowing a waiver of prospective informed consent: the diaspirin cross-linked hemoglobin traumatic hemorrhagic shock efficacy trial. ( Bechhofer, R; Berry, DA; Blue, JW; Cook, T; Cryer, H; Fisher, M; Fost, N; Houghton, J; Krome, R; Lewis, RJ; Washington, GR, 2001)
"Rats with a 10 cm full-thickness incisional wound and a 15 mL/kg hemorrhage were either not resuscitated or resuscitated with blood or diaspirin cross-linked hemoglobin (DCLHb)."7.69Cellular responses to surgical trauma, hemorrhage, and resuscitation with diaspirin cross-linked hemoglobin in rats. ( Burris, D; Leppäniemi, A; Li, Y; Malcolm, D; Nielsen, TB; Pacheco, ND; Pikoulis, E; Rollwagen, FM; Soltero, R; Sun, L; Xu, L, 1997)
"Tiaprofenic acid was shown to be better than aspirin in relieving pain by clinical assessment although both drugs were equally effective according to patients daily assessment."6.65A comparative double-blind study of tiaprofenic acid and aspirin in the treatment of muscular rheumatism, fibrositis, sprains and soft tissue injuries in general practice. ( Donald, JF; Molla, AL, 1980)
"Aspirin as added prophylaxis for DVT in trauma patients needs to be further evaluated."5.43Aspirin as added prophylaxis for deep vein thrombosis in trauma: A retrospective case-control study. ( Bansal, V; Brill, JB; Calvo, RY; Lewis, PR; Shackford, SR; Sise, MJ; Wallace, JD, 2016)
"In the clinical trial of diaspirin cross-linked hemoglobin (DCLHb), optimal therapy required the immediate enrollment of patients with severe, uncompensated, traumatic hemorrhagic shock."5.09The informed consent process and the use of the exception to informed consent in the clinical trial of diaspirin cross-linked hemoglobin (DCLHb) in severe traumatic hemorrhagic shock. DCLHb Traumatic Hemorrhagic Shock study group. ( Cipolle, M; Gens, D; Houghton, J; Koenigsberg, M; Mallory, MN; Rodman, G; Runge, J; Sloan, EP, 1999)
"A double-blind, non-crossover, randomized trial was carried out in 50 patients suffering from pain following trauma to compare the therapeutic effectiveness and tolerance of 200 mg tiaprofenic acid and 600 mg aspirin given 3-times daily for 7 days."5.05A comparative trial of tiaprofenic acid ('Surgam') versus aspirin in the control of pain following injury. ( Cutting, CJ; Thornton, EJ, 1981)
"The efficacy and safety of fenoprofen calcium (Nalfon, Dista, Indianapolis, IN) and aspirin for treating acute inflammatory soft tissue injuries were compared in a 3 to 10-day randomized, double-blind, parallel study of 100 patients with bruise (1), bursitis (33), ligamentous strain (8), myofascitis (43), and tendinitis (15)."5.05Fenoprofen calcium versus aspirin in the treatment of acute inflammatory soft-tissue injuries. ( McIlwain, HH, 1985)
"The majority of traumatic aneurysms can be managed with an antiplatelet regimen of 325 mg aspirin daily and serial imaging."3.80Extracranial traumatic aneurysms due to blunt cerebrovascular injury. ( Falola, M; Foreman, PM; Griessenauer, CJ; Harrigan, MR, 2014)
"To assess the ability of the shock index (SI) to predict 28-day mortality in traumatic hemorrhagic shock patients treated in the diaspirin cross-linked hemoglobin (DCLHb) resuscitation clinical trials."3.80Shock index and prediction of traumatic hemorrhagic shock 28-day mortality: data from the DCLHb resuscitation clinical trials. ( Clark, JM; Koenigsberg, M; Philbin, N; Sloan, EP; Weir, WB, 2014)
"Diaspirin cross-linked hemoglobin (DCLHb) has demonstrated a pressor effect that could adversely affect traumatic hemorrhagic shock patients through diminished perfusion to vital organs, causing base deficit (BD) and lactate abnormalities."3.76Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation. ( Gao, W; Koenigsberg, MD; Philbin, NB; Sloan, EP, 2010)
" This large, multicenter, randomized clinical trial was designed to compare the addition of diaspirin cross-linked hemoglobin (DCLHb) with standard care in the initial resuscitation of adults experiencing severe, uncompensated, traumatic hemorrhagic shock."3.71Monitoring a clinical trial conducted under the Food and Drug Administration regulations allowing a waiver of prospective informed consent: the diaspirin cross-linked hemoglobin traumatic hemorrhagic shock efficacy trial. ( Bechhofer, R; Berry, DA; Blue, JW; Cook, T; Cryer, H; Fisher, M; Fost, N; Houghton, J; Krome, R; Lewis, RJ; Washington, GR, 2001)
"Rats with a 10 cm full-thickness incisional wound and a 15 mL/kg hemorrhage were either not resuscitated or resuscitated with blood or diaspirin cross-linked hemoglobin (DCLHb)."3.69Cellular responses to surgical trauma, hemorrhage, and resuscitation with diaspirin cross-linked hemoglobin in rats. ( Burris, D; Leppäniemi, A; Li, Y; Malcolm, D; Nielsen, TB; Pacheco, ND; Pikoulis, E; Rollwagen, FM; Soltero, R; Sun, L; Xu, L, 1997)
"Tiaprofenic acid was shown to be better than aspirin in relieving pain by clinical assessment although both drugs were equally effective according to patients daily assessment."2.65A comparative double-blind study of tiaprofenic acid and aspirin in the treatment of muscular rheumatism, fibrositis, sprains and soft tissue injuries in general practice. ( Donald, JF; Molla, AL, 1980)
"Flurbiprofen was more effective than aspirin in producing analgesia (when daily pain scores were considered) after day 2 (p less than 0."2.64A comparative study of flurbiprofen and aspirin in soft tissue trauma. ( Muckle, DS, 1976)
"High ADP inhibition after trauma is common, limiting its utility to accurately identify preinjury APA use."1.62Thromboelastography with platelet mapping: Limited predictive ability in detecting preinjury antiplatelet agent use. ( Barton, CA; Dewey, EN; Goodman, A; Oetken, HJ; Roberti, GJ; Schreiber, M, 2021)
"Blunt trauma accounted for 99% of patients, and the median Injury Severity Score was 9 (interquartile range, 4-14)."1.46Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial. ( Barmparas, G; Bosarge, P; Brown, CV; Bukur, M; Carrick, MM; Catalano, RD; Coimbra, R; Holly-Nicolas, J; Inaba, K; Kaminski, S; Klein, AL; Kobayashi, L; Kopelman, T; Ley, EJ; Martinez, EM; Moore, FO; Murry, J; Nirula, R; Paul, D; Quick, J; Rivera, O; Schreiber, M, 2017)
"Aspirin as added prophylaxis for DVT in trauma patients needs to be further evaluated."1.43Aspirin as added prophylaxis for deep vein thrombosis in trauma: A retrospective case-control study. ( Bansal, V; Brill, JB; Calvo, RY; Lewis, PR; Shackford, SR; Sise, MJ; Wallace, JD, 2016)
"A total of 3,436 trauma patients were identified, of whom 456 were taking anticoagulants (warfarin, n = 91 patients; aspirin, n = 228; clopidogrel, n = 43; and various combinations, n = 94)."1.37Impact of preinjury warfarin and antiplatelet agents on outcomes of trauma patients. ( Arnold-Lloyd, T; Ata, A; Bonville, DJ; Jahraus, CB; Rosati, C; Salem, L; Stain, SC, 2011)
"We report on a severely injured trauma patient who suffered a high velocity motorcycle accident."1.36High-dose fibrinogen concentrate for haemostatic therapy of a major trauma patient with recent clopidogrel and aspirin intake. ( Hanke, A; Posch, A; Schöchl, H; Solomon, C; Voelckel, W, 2010)
"The Los Angeles County Medical Center trauma registry was used to obtain injury demographics, medications, and daily platelet counts for injured patients 16 years of age or older admitted between July 2005 and February 2008."1.35Extreme thrombocytosis in trauma patients: are antiplatelet agents the answer? ( Barmparas, G; Demetriades, D; Green, D; Inaba, K; Plurad, D; Saadi, Z; Salim, A; Talving, P, 2009)
"In selected cases of traumatic carotid artery dissections, endovascular stent-assisted angioplasty immediately restored the integrity of the vessel lumen and prevented efficiently the occurrence of new ischemic events, without additional anticoagulation."1.33Endovascular stent-assisted angioplasty in the management of traumatic internal carotid artery dissections. ( Ben-Hur, T; Cohen, JE; Gomori, JM; Rajz, G; Umansky, F, 2005)
"Of practical implication in traumatology is the finding that, for both paracetamol and glucocorticoids, almost the same reductions were recorded in swelling and pain whether the drug was administered prior to surgery or 2-3 hours afterwards."1.29[Anti-inflammatory agents in acute tissue trauma. Choice and effects]. ( Løkken, P; Skjelbred, P, 1993)
"The optimal management for traumatic arterial intimal injuries is unresolved."1.29Arterial intimal flaps: a comparison of primary repair, aspirin, and endovascular excision in an experimental model. ( DeFouw, D; Durán, WN; Hernández-Maldonado, JJ; Hobson, RW; Neville, R; Padberg, FT; Teehan, E, 1993)
"Circular burns were inflicted on anaesthetized animals which were killed 30 min, 2 h or 4 h after burning."1.26On the enzymatic response to injury and its mediators. ( Nieminen, L; Raekallio, J, 1979)
"In anesthetized dogs soft tissue trauma resulting in hypovolemia was associated with pulmonary trapping of 51Cr tagged platelets."1.25Development and treatment of post-traumatic pulmonary platelet trapping. ( Peer, RM; Schwartz, SI, 1975)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199028 (47.46)18.7374
1990's8 (13.56)18.2507
2000's8 (13.56)29.6817
2010's13 (22.03)24.3611
2020's2 (3.39)2.80

Authors

AuthorsStudies
Barton, CA1
Oetken, HJ1
Roberti, GJ1
Dewey, EN1
Goodman, A1
Schreiber, M2
Jávor, P1
Rárosi, F1
Horváth, T1
Török, L1
Hartmann, P1
Kobayashi, L1
Barmparas, G2
Bosarge, P1
Brown, CV1
Bukur, M1
Carrick, MM1
Catalano, RD1
Holly-Nicolas, J1
Inaba, K2
Kaminski, S1
Klein, AL1
Kopelman, T1
Ley, EJ1
Martinez, EM1
Moore, FO1
Murry, J1
Nirula, R1
Paul, D1
Quick, J1
Rivera, O1
Coimbra, R1
Ting, LH1
Feghhi, S1
Taparia, N1
Smith, AO1
Karchin, A1
Lim, E1
John, AS1
Wang, X1
Rue, T1
White, NJ1
Sniadecki, NJ1
Taylor, G1
Osinski, D1
Thevenin, A1
Devys, JM1
Foreman, PM1
Griessenauer, CJ1
Falola, M1
Harrigan, MR1
Sloan, EP4
Koenigsberg, M2
Clark, JM1
Weir, WB1
Philbin, N1
Singletary, EM2
Zideman, DA2
De Buck, ED1
Chang, WT1
Jensen, JL2
Swain, JM2
Woodin, JA1
Blanchard, IE1
Herrington, RA1
Pellegrino, JL2
Hood, NA1
Lojero-Wheatley, LF2
Markenson, DS1
Yang, HJ1
Charlton, NP1
Epstein, JL1
Ferguson, JD1
MacPherson, AI1
Smith, WW1
Brill, JB1
Calvo, RY1
Wallace, JD1
Lewis, PR1
Bansal, V1
Sise, MJ1
Shackford, SR1
Kurak, J1
Zając, P1
Czyżewski, D1
Kucharski, R1
Grzanka, R1
Kasperska-Zajac, A1
Koczy, B1
Saadi, Z1
Salim, A1
Talving, P1
Plurad, D1
Green, D1
Demetriades, D1
Undas, A2
Siudak, Z1
Brummel-Ziedins, K1
Mann, KG2
Tracz, W1
Koenigsberg, MD1
Philbin, NB1
Gao, W1
Schöchl, H1
Posch, A1
Hanke, A1
Voelckel, W1
Solomon, C1
Bonville, DJ1
Ata, A1
Jahraus, CB1
Arnold-Lloyd, T1
Salem, L1
Rosati, C1
Stain, SC1
Moore, EE1
MOINADE, S1
CORGILL, DA1
LIGON, CW1
DEFELICE, EA1
Cohen, JE1
Ben-Hur, T1
Rajz, G1
Umansky, F1
Gomori, JM1
Collier, HO1
Slichter, SJ1
Donald, JF1
Molla, AL1
Mayer, TG1
Ruoff, GE1
Cutting, CJ1
Thornton, EJ1
Pyshkin, SA1
Kravets, NS1
Rylov, AI1
Skjelbred, P1
Løkken, P1
Hernández-Maldonado, JJ1
Padberg, FT1
Teehan, E1
Neville, R1
DeFouw, D1
Durán, WN1
Hobson, RW1
Xu, L1
Sun, L1
Rollwagen, FM1
Li, Y1
Pacheco, ND1
Pikoulis, E1
Leppäniemi, A1
Soltero, R1
Burris, D1
Malcolm, D1
Nielsen, TB1
Walker, M1
Hulme, TA1
Rippon, MG1
Walmsley, RS1
Gunnigle, S1
Lewin, M1
Winsey, S1
Wagner, T1
Houghton, J2
Gens, D1
Cipolle, M1
Runge, J1
Mallory, MN1
Rodman, G1
Lewis, RJ1
Berry, DA1
Cryer, H1
Fost, N1
Krome, R1
Washington, GR1
Blue, JW1
Bechhofer, R1
Cook, T1
Fisher, M1
Brummel, K1
Musial, J1
Szczeklik, A1
Arnoldo, BD1
Minei, JP1
Adhikari, M1
Pillay, T1
Nathoo, N1
Peer, RM2
Schwartz, SI2
Raekallio, J1
Nieminen, L1
Zinner, MJ1
Turtinen, L1
Gurll, NJ1
Weinger, RS1
Cimo, PL1
Muckle, DS2
Saggau, W1
Bleyl, U1
Brückner, UB1
Klöss, T1
Leinberger, H1
Metzker, M1
Schmier, J1
Kakkar, VV1
Kelly, GL1
Eiseman, B1
Clagett, GP1
Anderson, FA1
Levine, MN1
Salzman, EW1
Wheeler, HB1
de la Cuadra, JL1
Jeanneret, C1
Furlan, M1
Beck, EA1
McIlwain, HH1
Lamphier, T1
Rodriguez, A1
Richards, D1
Raĭtsina, SS1
Delektorskiĭ, VV1
Gladkova, NS1
Davydova, AI1
Szirmai, E1
Sachs, V1
Doutre, LP1
Périssat, J1
Hunt, TK1
Bergentz, SE1
Anggård, E1
Arcadio, AF1
Mazenod, B1
Milinkovitch, P1
Moulary, A1
Nordenram, A1
Bang, G1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Mitochondrial Dysfunction in Trauma-related Coagulopathy - Is There Causality? - Study Protocol for a Prospective Observational Study[NCT05004844]40 participants (Anticipated)Observational2021-10-31Not yet recruiting
Haemocomplettan® P in Patients Experiencing Acute Bleeding While Undergoing Aortic Replacement Surgery[NCT00701142]Phase 280 participants (Actual)Interventional2008-06-30Completed
A Phase II, Randomized, Single-Blind, Controlled Clinical Trial to Evaluate the Efficacy and Safety of Hemolink[Tm] (o-Raffinose Cross-Linked Human Hemoglobin) in Subjects Undergoing Primary Coronary Artery Bypass Grafting Surgery[NCT00038454]Phase 2/Phase 3180 participants InterventionalSuspended
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for aspirin and Injuries

ArticleYear
Part 9: First Aid: 2015 International Consensus on First Aid Science With Treatment Recommendations.
    Circulation, 2015, Oct-20, Volume: 132, Issue:16 Suppl 1

    Topics: Airway Management; Aspirin; Asthma; Cardiopulmonary Resuscitation; Chest Pain; Emergencies; Emergenc

2015
Part 15: First Aid: 2015 American Heart Association and American Red Cross Guidelines Update for First Aid.
    Circulation, 2015, Nov-03, Volume: 132, Issue:18 Suppl 2

    Topics: Anaphylaxis; Aspirin; Burns; Chest Pain; Dehydration; Emergency Medical Services; Epinephrine; First

2015
Identification & management of defects in platelet hemostasis in massively transfused patients.
    Progress in clinical and biological research, 1982, Volume: 108

    Topics: Animals; Aspirin; Bleeding Time; Blood Preservation; Blood Transfusion; Cardiopulmonary Bypass; Cell

1982
Potential of hemoglobin-based oxygen carriers in trauma patients.
    Current opinion in critical care, 2001, Volume: 7, Issue:6

    Topics: Aspirin; Blood Substitutes; Clinical Trials as Topic; Fluorocarbons; Hemoglobins; Humans; Oxygen; Ra

2001
Deep vein thrombosis. Detection and prevention.
    Circulation, 1975, Volume: 51, Issue:1

    Topics: Administration, Oral; Anticoagulants; Aspirin; Dextrans; Dipyridamole; Female; Fibrinogen; Heparin;

1975
Prevention of venous thromboembolism.
    Chest, 1992, Volume: 102, Issue:4 Suppl

    Topics: Anticoagulants; Aspirin; Bandages; Cerebrovascular Disorders; Gravity Suits; Humans; Myocardial Infa

1992
[Analgesic drugs for peroral use].
    Lakartidningen, 1970, Dec-14, Volume: 67

    Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Headache; Humans; Ischemia; Kinetics; Neoplasms; Neuralg

1970

Trials

8 trials available for aspirin and Injuries

ArticleYear
A comparative double-blind study of tiaprofenic acid and aspirin in the treatment of muscular rheumatism, fibrositis, sprains and soft tissue injuries in general practice.
    The Journal of international medical research, 1980, Volume: 8, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Female; Fibromyalgia;

1980
Clinical evaluation of zomepirac in the treatment of acute orthopedic pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug C

1980
A comparative trial of tiaprofenic acid ('Surgam') versus aspirin in the control of pain following injury.
    Pharmatherapeutica, 1981, Volume: 2, Issue:8

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic;

1981
The informed consent process and the use of the exception to informed consent in the clinical trial of diaspirin cross-linked hemoglobin (DCLHb) in severe traumatic hemorrhagic shock. DCLHb Traumatic Hemorrhagic Shock study group.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1999, Volume: 6, Issue:12

    Topics: Adult; Aspirin; Chi-Square Distribution; Clinical Trials as Topic; Female; Hemoglobins; Humans; Info

1999
A comparative study of flurbiprofen and aspirin in soft tissue trauma.
    British journal of sports medicine, 1976, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Drug Evaluation; Flu

1976
Fenoprofen calcium versus aspirin in the treatment of acute inflammatory soft-tissue injuries.
    Journal of medicine, 1985, Volume: 16, Issue:4

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Fenoprofen; Humans; Inf

1985
Double-blind study of the analgesic effect of ethoheptazine-aspirin.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:7

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Aspirin; Azepines; Clinical Trials as Topic; Depressi

1974
Comparative study of ibuprofen and aspirin in soft-tissue injuries.
    Rheumatology and rehabilitation, 1974, Volume: 13, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Athletic Injuries; Clinical Trials as Topic; Humans; Pain;

1974

Other Studies

44 other studies available for aspirin and Injuries

ArticleYear
Thromboelastography with platelet mapping: Limited predictive ability in detecting preinjury antiplatelet agent use.
    The journal of trauma and acute care surgery, 2021, 11-01, Volume: 91, Issue:5

    Topics: Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Blood Platelets; Domperidone; Female; Hemorrhage

2021
Mitochondrial Dysfunction in Trauma-Related Coagulopathy: Is There Causality? Study Protocol for a Prospective Observational Study.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2023, Volume: 64, Issue:2

    Topics: Aspirin; Blood Coagulation Disorders; Hemorrhage; Hemostasis; Humans; Observational Studies as Topic

2023
Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial.
    The journal of trauma and acute care surgery, 2017, Volume: 82, Issue:5

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Clopidogrel; Dabigatran; Female; Humans; Injury

2017
Contractile forces in platelet aggregates under microfluidic shear gradients reflect platelet inhibition and bleeding risk.
    Nature communications, 2019, 03-13, Volume: 10, Issue:1

    Topics: Adult; Aspirin; Blood Coagulation; Blood Platelets; Computer Simulation; Cross-Sectional Studies; Dr

2019
Is platelet transfusion efficient to restore platelet reactivity in patients who are responders to aspirin and/or clopidogrel before emergency surgery?
    The journal of trauma and acute care surgery, 2013, Volume: 74, Issue:5

    Topics: Aspirin; Blood Platelets; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregatio

2013
Extracranial traumatic aneurysms due to blunt cerebrovascular injury.
    Journal of neurosurgery, 2014, Volume: 120, Issue:6

    Topics: Adolescent; Adult; Aneurysm; Aspirin; Cerebral Angiography; Cerebrovascular Trauma; Cohort Studies;

2014
Shock index and prediction of traumatic hemorrhagic shock 28-day mortality: data from the DCLHb resuscitation clinical trials.
    The western journal of emergency medicine, 2014, Volume: 15, Issue:7

    Topics: Adult; Aspirin; Blood Substitutes; Emergency Medical Services; Europe; Female; Fluid Therapy; Hemogl

2014
Aspirin as added prophylaxis for deep vein thrombosis in trauma: A retrospective case-control study.
    The journal of trauma and acute care surgery, 2016, Volume: 80, Issue:4

    Topics: Anticoagulants; Aspirin; Case-Control Studies; Female; Humans; Leg; Male; Middle Aged; Prognosis; Re

2016
Evaluation of platelet function using PFA-100® in patients treated with Acetylsalicylic acid and qualified for Trauma and Orthopedic surgery procedures.
    Platelets, 2016, Volume: 27, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Coagulation Tests; Blood Platelets; Clinical Decision

2016
Extreme thrombocytosis in trauma patients: are antiplatelet agents the answer?
    The American surgeon, 2009, Volume: 75, Issue:10

    Topics: Adolescent; Adult; Aspirin; Cohort Studies; Female; Humans; Incidence; Length of Stay; Male; Middle

2009
Prothrombinase formation at the site of microvascular injury and aspirin resistance: the effect of simvastatin.
    Thrombosis research, 2010, Volume: 125, Issue:3

    Topics: Arachidonic Acid; Aspirin; Bleeding Time; Drug Combinations; Drug Resistance; Factor X; Fasting; Hum

2010
Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation.
    The Journal of trauma, 2010, Volume: 68, Issue:5

    Topics: Acidosis, Lactic; Adult; Aspirin; Emergency Medical Services; Emergency Treatment; Europe; Fluid The

2010
High-dose fibrinogen concentrate for haemostatic therapy of a major trauma patient with recent clopidogrel and aspirin intake.
    Scandinavian journal of clinical and laboratory investigation, 2010, Volume: 70, Issue:6

    Topics: Aspirin; Clopidogrel; Drug Interactions; Fibrinogen; Glasgow Coma Scale; Hemorrhage; Hemostatics; Hu

2010
Impact of preinjury warfarin and antiplatelet agents on outcomes of trauma patients.
    Surgery, 2011, Volume: 150, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Child, Preschool; Clopid

2011
Blood substitutes: the future is now.
    Journal of the American College of Surgeons, 2003, Volume: 196, Issue:1

    Topics: Aspirin; Blood Substitutes; Blood Transfusion; Clinical Trials as Topic; Erythrocytes; Forecasting;

2003
The clinical trials of diaspirin cross-linked hemoglobin (DCLHb) in severe traumatic hemorrhagic shock: the tale of two continents.
    Intensive care medicine, 2003, Volume: 29, Issue:3

    Topics: Aspirin; Blood Substitutes; Clinical Trials as Topic; European Union; Hemoglobins; Humans; Shock, He

2003
[EXPERIMENTATION AND ACTION OF TH-2152 IN THE CLINICAL MEDICINE DEPARTMENT].
    Gazette medicale de France, 1964, Jun-10, Volume: 71

    Topics: Arteritis; Aspirin; Bicarbonates; Biomedical Research; Clinical Medicine; Humans; Influenza, Human;

1964
DOUBLE-BLIND COMPARISON OF NAMOXYRATE, CODEINE, ASPIRIN, AND PLACEBO.
    Current therapeutic research, clinical and experimental, 1965, Volume: 7

    Topics: Analgesia; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Biomedical Research; Codeine

1965
Endovascular stent-assisted angioplasty in the management of traumatic internal carotid artery dissections.
    Stroke, 2005, Volume: 36, Issue:4

    Topics: Adult; Angiography; Angioplasty; Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis I

2005
Fenamates as antagonists of bronchoconstriction and nociception induced by bradykinin and other substances.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Adenosine Triphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Bronchi;

1966
[Use of necrectomy in the treatment of suppurative infective wounds].
    Klinicheskaia khirurgiia, 1994, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anti-Infective Agents; Aspirin; Child; Child, P

1994
[Anti-inflammatory agents in acute tissue trauma. Choice and effects].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1993, Feb-10, Volume: 113, Issue:4

    Topics: Acetaminophen; Adolescent; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Stero

1993
Arterial intimal flaps: a comparison of primary repair, aspirin, and endovascular excision in an experimental model.
    The Journal of trauma, 1993, Volume: 34, Issue:4

    Topics: Angioscopy; Animals; Arteries; Aspirin; Dogs; Endothelium, Vascular; Evaluation Studies as Topic; Fe

1993
Cellular responses to surgical trauma, hemorrhage, and resuscitation with diaspirin cross-linked hemoglobin in rats.
    The Journal of trauma, 1997, Volume: 42, Issue:1

    Topics: Animals; Aspirin; Bacterial Translocation; Blood Pressure; Cell Division; Hemoglobins; Hemorrhage; I

1997
In vitro model(s) for the percutaneous delivery of active tissue repair agents.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:12

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Aspirin; Bridged Bicyclo Compounds, He

1997
[Acetylsalicylic acid and surgical risk].
    Der Internist, 1998, Volume: 39, Issue:2

    Topics: Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Humans; Postoperative Hemorrhage; Risk Fac

1998
Monitoring a clinical trial conducted under the Food and Drug Administration regulations allowing a waiver of prospective informed consent: the diaspirin cross-linked hemoglobin traumatic hemorrhagic shock efficacy trial.
    Annals of emergency medicine, 2001, Volume: 38, Issue:4

    Topics: Aspirin; Critical Illness; Female; Follow-Up Studies; Hemoglobins; Humans; Informed Consent; Injury

2001
Blood coagulation at the site of microvascular injury: effects of low-dose aspirin.
    Blood, 2001, Oct-15, Volume: 98, Issue:8

    Topics: Adult; Aspirin; Bleeding Time; Blood Coagulation; Blotting, Western; Factor XIII; Fibrinogen; Humans

2001
Aspirin and trauma--uncommon and preventable causes of intracranial haemorrhage in the newborn.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2002, Volume: 92, Issue:5

    Topics: Adult; Aspirin; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Int

2002
Development and treatment of post-traumatic pulmonary platelet trapping.
    Annals of surgery, 1975, Volume: 181, Issue:4

    Topics: Animals; Aspirin; Biopsy; Blood Cell Count; Blood Platelets; Chromium Radioisotopes; Dextrans; Disea

1975
On the enzymatic response to injury and its mediators.
    Medical biology, 1979, Volume: 57, Issue:4

    Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Burns;

1979
Stress ulceration and the gastric mucosal barrier.
    The American surgeon, 1975, Volume: 41, Issue:4

    Topics: Animals; Aspirin; Bile Acids and Salts; Cats; Disease Models, Animal; Ethanol; Gastric Acidity Deter

1975
Platelet function abnormalities.
    Blood, 1979, Volume: 53, Issue:6

    Topics: Aspirin; Blood Platelets; Hemorrhage; Humans; Wounds and Injuries

1979
[Pulmonary hemodynamics, coagulation and morphological changes in the lung after thrombocyte aggregation inhibition and intravasal coagulation in experimental trauma and hemorrhagic shock].
    Langenbecks Archiv fur Chirurgie, 1976, Volume: Suppl

    Topics: Airway Resistance; Animals; Aspirin; Dipyridamole; Dogs; Hemodynamics; Lung; Platelet Aggregation; S

1976
Civilian vascular injuries.
    The Journal of trauma, 1975, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aneurysm; Arteries; Arteriovenous Fistula; Aspirin; Blood Vess

1975
[A modified in vivo platelet retention test in the evaluation of primary hemostasis].
    Schweizerische medizinische Wochenschrift, 1987, Nov-14, Volume: 117, Issue:46

    Topics: Aspirin; Blood Platelet Disorders; Blood Platelets; Female; Hemostasis; Humans; Male; Platelet Adhes

1987
[Prevention of the development of post-traumatic testicular atrophy in rats by administering aspirin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1974, Volume: 78, Issue:10

    Topics: Animals; Aspirin; Atrophy; Biological Transport; Blood; Male; Organ Size; Rats; Sertoli Cells; Sperm

1974
[Experimental investigation of the effect of a combination of quinine, lithium and salicylic acid by means of various methods].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:9

    Topics: Angiography; Anti-Inflammatory Agents; Arterial Occlusive Diseases; Arthritis; Aspirin; Drug Combina

1974
[Propofan as an antalgic in general surgery. Apropos of 50 cases].
    Bordeaux medical, 1972, Volume: 5, Issue:18

    Topics: Acetaminophen; Analgesics; Aspirin; Bone Diseases; Caffeine; Chlorpheniramine; Dextropropoxyphene; D

1972
Injury and repair in acute gastroduodenal ulceration.
    American journal of surgery, 1973, Volume: 125, Issue:1

    Topics: Acute Disease; Aspirin; Burns; Cushing Syndrome; Duodenal Ulcer; Gastric Mucosa; Humans; Infections;

1973
[Proceedings: Bleeding problems due to platelet disorders (author's transl)].
    Langenbecks Archiv fur Chirurgie, 1973, Volume: 334

    Topics: Aspirin; Blood Cell Count; Blood Platelet Disorders; Blood Platelets; Humans; Kidney Failure, Chroni

1973
Prevention of pulmonary platelet trapping following trauma.
    Surgical forum, 1973, Volume: 24

    Topics: Animals; Aspirin; Dextrans; Dogs; Platelet Adhesiveness; Platelet Aggregation; Pulmonary Embolism; W

1973
[Value of lysine acetylsalicylate in pains of traumatic origin (apropos of 86 cases)].
    Lyon medical, 1972, Feb-13, Volume: 227, Issue:3

    Topics: Adolescent; Adult; Aged; Analgesics; Aspirin; Child; Fractures, Bone; Humans; Joint Dislocations; Ly

1972
Bone-healing after topical application of Apernyl. A histopathologic study in guinea pigs.
    Scandinavian journal of dental research, 1970, Volume: 78, Issue:6

    Topics: Animals; Aspirin; Bone Regeneration; Female; Guinea Pigs; Maxilla; Tooth Extraction; Wound Healing;

1970