Page last updated: 2024-10-17

3-hydroxybutyric acid and Injuries

3-hydroxybutyric acid has been researched along with Injuries in 8 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation."5.30Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998)
"There were 100 adult trauma patients with Injury Severity Score (ISS) >18 were enrolled in this prospective, randomized, blinded study."2.73Beta-hydroxy-beta-methylbutyrate supplementation in critically ill trauma patients. ( Barber, A; Coates, JE; Fildes, JJ; Frisch, DA; Kuhls, DA; MacIntyre, AD; Musngi, MD; Nielson, J; Rathmacher, JA, 2007)
"Carnitine is an AA itself and so the amount of excreted alpha-amino nitrogen will increase; additionally the reabsorption of AA in the proximal renal tubulus may be inhibited by carnitine."2.66[Experiences with L-carnitine in the post-stress phase]. ( Balogh, D; Hackl, JM; Legenstein, E; Musil, HE, 1986)
"Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation."1.30Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Wu, X1
Miao, D1
Liu, Z1
Liu, K1
Zhang, B1
Li, J1
Li, Y1
Qi, J1
Kuhls, DA1
Rathmacher, JA1
Musngi, MD1
Frisch, DA1
Nielson, J1
Barber, A1
MacIntyre, AD1
Coates, JE1
Fildes, JJ1
Barton, RN1
Cocks, RA1
Doyle, MO1
Chambers, H1
Jarvis, AM1
Cockram, MS1
McGilp, IM1
Wang, W1
Wang, P1
Chaudry, IH1
Amaral, JF1
Shearer, JD1
Mastrofrancesco, B1
Gann, DS1
Caldwell, MD1
Balogh, D1
Hackl, JM1
Legenstein, E1
Musil, HE1
Lund, J1
Stjernström, H1
Bergholm, U1
Jorfeldt, L1
Vinnars, E1
Wiklund, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit (STROMA-ICU)[NCT02773771]Phase 2/Phase 30 participants (Actual)Interventional2017-01-31Withdrawn (stopped due to Per IRB submission history, submission declined and withdrawn. PI no longer at institution.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for 3-hydroxybutyric acid and Injuries

ArticleYear
Beta-hydroxy-beta-methylbutyrate supplementation in critically ill trauma patients.
    The Journal of trauma, 2007, Volume: 62, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adult; Arginine; Biomarkers; Enteral Nutrition; Female; Glutamine; Humans; Ma

2007
[Experiences with L-carnitine in the post-stress phase].
    Infusionstherapie und klinische Ernahrung, 1986, Volume: 13, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetylcarnitine; Adolescent; Adult; Carnitine; Clinical Trials as Topic; Doub

1986
The exchange of blood-borne amino acids in the leg during abdominal surgical trauma: effects of glucose infusion.
    Clinical science (London, England : 1979), 1986, Volume: 71, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Arteries; Blood Glucose; Cholecystectomy; Female; Glucose

1986

Other Studies

5 other studies available for 3-hydroxybutyric acid and Injuries

ArticleYear
β-hydroxybutyrate antagonizes aortic endothelial injury by promoting generation of VEGF in diabetic rats.
    Tissue & cell, 2020, Volume: 64

    Topics: 3-Hydroxybutyric Acid; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Histo

2020
Time course of the early pituitary-adrenal and metabolic responses to accidental injury.
    The Journal of trauma, 1995, Volume: 39, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Bloo

1995
Bruising and biochemical measures of stress, dehydration and injury determined at slaughter in sheep transported from farms or markets.
    The British veterinary journal, 1996, Volume: 152, Issue:6

    Topics: 3-Hydroxybutyric Acid; Abattoirs; Analysis of Variance; Animals; Creatine Kinase; Dehydration; Hydro

1996
Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock.
    Critical care medicine, 1998, Volume: 26, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase; Animal Feed; Animals; Disease Models, Animal; Fatty A

1998
The temporal characteristics of the metabolic and endocrine response to injury.
    The Journal of trauma, 1988, Volume: 28, Issue:9

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adrenocorticotropic Hormone; Animals; Blood Glucose; Body Wate

1988