Compounds > pyrrobutamine

Page last updated: 2024-12-05

pyrrobutamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

pyrrobutamine: RN given refers to parent cpd without isomeric designation; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	5375785
CHEBI ID	135334
SCHEMBL ID	28347
MeSH ID	M0061616

Synonyms (14)

Synonym
pyrrolidine, 1-[4-(4-chlorophenyl)-3-phenyl-2-butenyl]-
pyrrobutamide
pyrrobutamine
91-82-7
CHEBI:135334
1-(4-(4-chlorophenyl)-3-phenylbut-2-enyl)pyrrolidine
SCHEMBL28347
pyrrolidine, 1-[.gamma.-(p-chlorobenzyl)cinnamyl]-
copyronil
1-[(2z)-4-(4-chlorophenyl)-3-phenyl-2-butenyl]pyrrolidine #
WDYYVNNRTDZKAZ-UNOMPAQXSA-N
DB13846
Q63395560
1-(4-(4-chlorophenyl)-3-phenylbut-2-en-1-yl)pyrrolidine

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	8 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
methapyrilene Methapyrilene: Histamine H1 antagonist with sedative action used as a hypnotic and in allergies.. methapyrilene : A member of the class of ethylenediamine derivatives that is ethylenediamine in which one of the nitrogens is substituted by two methyl groups, and the other nitrogen is substituted by a 2-pyridyl group and a (2-thienyl)methyl group.	6.95	1	0	ethylenediamine derivative	anti-allergic agent; carcinogenic agent; H1-receptor antagonist; sedative
reserpine Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.. reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.	2.33	2	0	alkaloid ester; methyl ester; yohimban alkaloid	adrenergic uptake inhibitor; antihypertensive agent; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; first generation antipsychotic; plant metabolite; xenobiotic
cyclopentamine cyclopentamine: structure	6.95	1	0	secondary amino compound
cyclopentane Cyclopentanes: A group of alicyclic hydrocarbons with the general formula R-C5H9.. cyclopentanes : Cyclopentane and its derivatives formed by substitution.	1.95	1	0	cycloalkane; cyclopentanes; volatile organic compound	non-polar solvent

Condition	Indicated	Relationship Strength	Studies	Trials
Disease A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.	0	1.93	1	0
Nasal Diseases [description not available]	0	2.33	2	0
Paranasal Sinus Diseases Diseases affecting or involving the PARANASAL SINUSES and generally manifesting as inflammation, abscesses, cysts, or tumors.	0	1.93	1	0
Fungal Diseases [description not available]	0	1.93	1	0
Dermatoses [description not available]	0	1.93	1	0
Mycoses Diseases caused by FUNGI.	0	1.93	1	0
Skin Diseases Diseases involving the DERMIS or EPIDERMIS.	0	1.93	1	0
Injuries Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.	0	1.93	1	0
Wounds and Injuries Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.	0	1.93	1	0