Page last updated: 2024-12-07

aminaftone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID84621
CHEBI ID135317
SCHEMBL ID12157532
MeSH IDM0066071

Synonyms (27)

Synonym
1,4-dihydroxy-3-methyl-2-naphthyl 4-aminobenzoate
capillarema (tn)
aminaphtone
D07566
14748-94-8
aminaftone
CHEBI:135317
aminaphthone
(1,4-dihydroxy-3-methylnaphthalen-2-yl) 4-aminobenzoate
einecs 238-809-8
unii-03jlx11pe9
03jlx11pe9 ,
capilarema
3-methyl-1,2,4-naphthalenetriol-2-(4-aminobenzoate)
SCHEMBL12157532
aminonaphthone
1,2,4-naphthalenetriol, 3-methyl-, 2-(4-aminobenzoate)
aminaphtone [who-dd]
1,2,4-naphthalenetriol, 3-methyl-, 2-(p-aminobenzoate)
aminaphthone [mart.]
capillarema
DTXSID00163725
HY-19890
CS-6667
DB13039
Q17620495
AKOS040741107

Research Excerpts

Overview

Aminaftone is a drug used for the treatment of capillary disorders. It has a mechanism of action that is not fully understood.

ExcerptReferenceRelevance
"Aminaftone is a drug used for the treatment of capillary disorders but which has a mechanism of action that is not fully understood."( Aminaftone, a derivative of 4-aminobenzoic acid, downregulates endothelin-1 production in ECV304 Cells: an in vitro Study.
Beretta, L; Colombo, G; Lenna, S; Salazar, G; Santaniello, A; Scorza, R; Turcatti, F, 2008
)
2.51
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
naphtholsAny hydroxynaphthalene derivative that has a single hydroxy substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (21)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (23.81)18.7374
1990's0 (0.00)18.2507
2000's4 (19.05)29.6817
2010's11 (52.38)24.3611
2020's1 (4.76)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 42.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index42.20 (24.57)
Research Supply Index3.26 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index56.78 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (42.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (19.05%)5.53%
Reviews3 (14.29%)6.00%
Case Studies3 (14.29%)4.05%
Observational0 (0.00%)0.25%
Other11 (52.38%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Double-blind Trial Between Clinical and Endovascular Treatment in Patients With Advanced Chronic Venous Insufficiency and Iliac Venous Obstruction [NCT02149212]Phase 450 participants (Actual)Interventional2013-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]