clonidine has been researched along with Injuries in 7 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonselective beta blockade (BB) and clonidine may abrogate catecholamine-mediated persistent injury-associated anemia." | 7.88 | The effects of beta blockade and clonidine on persistent injury-associated anemia. ( Brakenridge, SC; Croft, CA; Efron, PA; Loftus, TJ; Mohr, AM; Moore, FA; Rosenthal, MD; Smith, RS, 2018) |
| "Nonselective beta blockade (BB) and clonidine may abrogate catecholamine-mediated persistent injury-associated anemia." | 3.88 | The effects of beta blockade and clonidine on persistent injury-associated anemia. ( Brakenridge, SC; Croft, CA; Efron, PA; Loftus, TJ; Mohr, AM; Moore, FA; Rosenthal, MD; Smith, RS, 2018) |
| "Ninety adult trauma patients of American Society of Anesthesiologists physical status I-II, scheduled for lower limb surgery under subarachnoid block, were randomly allocated to one of three groups." | 2.78 | The analgesic effect of intrathecal dexmedetomidine or clonidine, with bupivacaine, in trauma patients undergoing lower limb surgery: a randomised, double-blind study. ( Batra, YK; Bharti, N; Jain, A; Kumar, P; Nikhar, SA; Solanki, SL, 2013) |
| "Propranolol and clonidine were administered by daily intraperitoneal injection until sacrifice on day seven." | 1.56 | Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress. ( Brakenridge, SC; Efron, PA; Kannan, KB; Loftus, TJ; Mira, JC; Mohr, AM, 2020) |
| "Childhood trauma is a risk factor for personality disorder." | 1.43 | GH response to intravenous clonidine challenge correlates with history of childhood trauma in personality disorder. ( Coccaro, EF; Fanning, JR; Lee, RJ, 2016) |
| "Clonidine was more potent in CCI then in CFA rats in reducing the response to cold." | 1.30 | The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models. ( Franssen, M; Goff, JR; Janni, G; Jasmin, L; Kohan, L, 1998) |
| "With early trauma, beta-adrenergic responsiveness and receptor number were significantly decreased." | 1.27 | Adrenergic control of adipocyte lipolysis in trauma and sepsis. ( Askanazi, J; Forse, RA; Hirsch, J; Kinney, JM; Leibel, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Loftus, TJ | 2 |
| Kannan, KB | 1 |
| Mira, JC | 1 |
| Brakenridge, SC | 2 |
| Efron, PA | 2 |
| Mohr, AM | 2 |
| Rosenthal, MD | 1 |
| Croft, CA | 1 |
| Smith, RS | 1 |
| Moore, FA | 1 |
| Lee, RJ | 1 |
| Fanning, JR | 1 |
| Coccaro, EF | 1 |
| Solanki, SL | 1 |
| Bharti, N | 1 |
| Batra, YK | 1 |
| Jain, A | 1 |
| Kumar, P | 1 |
| Nikhar, SA | 1 |
| Lavand'homme, PM | 1 |
| Eisenach, JC | 1 |
| Jasmin, L | 1 |
| Kohan, L | 1 |
| Franssen, M | 1 |
| Janni, G | 1 |
| Goff, JR | 1 |
| Forse, RA | 1 |
| Leibel, R | 1 |
| Askanazi, J | 1 |
| Hirsch, J | 1 |
| Kinney, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Caudal Epidural With Non Opioid Adjuvants in Lumbosacral Spine Surgery[NCT04411329] | 60 participants (Actual) | Interventional | 2020-06-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for clonidine and Injuries
| Article | Year |
|---|---|
The analgesic effect of intrathecal dexmedetomidine or clonidine, with bupivacaine, in trauma patients undergoing lower limb surgery: a randomised, double-blind study.
Topics: Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Clon | 2013 |
6 other studies available for clonidine and Injuries
| Article | Year |
|---|---|
Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress.
Topics: Animals; Clonidine; Corticosterone; Enzyme-Linked Immunosorbent Assay; Hematopoietic Stem Cells; Hep | 2020 |
The effects of beta blockade and clonidine on persistent injury-associated anemia.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Age Factors; Anemia; Blood Loss, | 2018 |
GH response to intravenous clonidine challenge correlates with history of childhood trauma in personality disorder.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Female; Growth Hormone; Humans; Male; Middle | 2016 |
Perioperative administration of the alpha2-adrenoceptor agonist clonidine at the site of nerve injury reduces the development of mechanical hypersensitivity and modulates local cytokine expression.
Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Clonidine; Cytokines; Drug Combinations; Hyper | 2003 |
The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Clonidine; Cold | 1998 |
Adrenergic control of adipocyte lipolysis in trauma and sepsis.
Topics: Adipose Tissue; Adult; Aged; Clonidine; Energy Metabolism; Female; Humans; Isoproterenol; Lipolysis; | 1987 |