n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Injuries in 3 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Following trauma, increased prostaglandin E2 (PGE2) levels may be important in immunodysregulation." | 1.31 | Blocking prostaglandin E2 after trauma attenuates pro-inflammatory cytokines and improves survival. ( Concannon, EM; Daly, JM; Mackrell, PJ; Naama, HA; Schaefer, PA; Shaftan, GW; Stapleton, PP; Strong, VE, 2000) |
| "On Day 7 after trauma, mice were sacrificed, serum was collected, and splenic macrophages were evaluated for PGE(2), LTB(4), IL-6, TNF-alpha, and NO production." | 1.31 | NS-398 treatment after trauma modifies NF-kappaB activation and improves survival. ( Concannon, EM; Daly, JM; Mack Strong, VE; Mackrell, PJ; Mestre, JR; Schaefer, PA; Smyth, GP; Stapleton, PP, 2001) |
| "Studies indicate that trauma-hemorrhage results in activation of Kupffer cells to release inflammatory mediators and it leads to immunosuppression and increased susceptibility to subsequent sepsis." | 1.31 | Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis. ( Bland, KI; Chaudry, IH; Cioffi, WG; Diodato, MD; Knöferl, MW; Schwacha, MG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strong, VE | 1 |
| Mackrell, PJ | 2 |
| Concannon, EM | 2 |
| Naama, HA | 1 |
| Schaefer, PA | 2 |
| Shaftan, GW | 1 |
| Stapleton, PP | 2 |
| Daly, JM | 2 |
| Mack Strong, VE | 1 |
| Mestre, JR | 1 |
| Smyth, GP | 1 |
| Knöferl, MW | 1 |
| Diodato, MD | 1 |
| Schwacha, MG | 1 |
| Cioffi, WG | 1 |
| Bland, KI | 1 |
| Chaudry, IH | 1 |
3 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Injuries
| Article | Year |
|---|---|
Blocking prostaglandin E2 after trauma attenuates pro-inflammatory cytokines and improves survival.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cyclooxygenase 2; Cyclooxygenase 2 In | 2000 |
NS-398 treatment after trauma modifies NF-kappaB activation and improves survival.
Topics: Animals; Bacterial Infections; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibit | 2001 |
Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; In | 2001 |