propranolol has been researched along with Injuries in 15 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-five severely injured trauma patients were studied in a prospective, randomized pilot trial." | 2.79 | Early propranolol administration to severely injured patients can improve bone marrow dysfunction. ( Alzate, WD; Bible, LE; Gore, AV; Livingston, DH; Mohr, AM; Pasupuleti, LV; Sifri, ZC; Song, KJ, 2014) |
| "Six-week PTSD symptoms and heart rate were assessed." | 2.75 | The efficacy of early propranolol administration at reducing PTSD symptoms in pediatric injury patients: a pilot study. ( Browne, L; Christopher, NC; Crow, JP; Delahanty, DL; Nugent, NR; Ostrowski, S, 2010) |
| "Propranolol and clonidine were administered by daily intraperitoneal injection until sacrifice on day seven." | 1.56 | Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress. ( Brakenridge, SC; Efron, PA; Kannan, KB; Loftus, TJ; Mira, JC; Mohr, AM, 2020) |
| "Propranolol (βB) was given immediately following resuscitation." | 1.37 | β-blockade protection of bone marrow following trauma: the role of G-CSF. ( Alzate, WD; Baranski, GM; Elhassan, IO; Hannoush, EJ; Livingston, DH; Mohr, AM; Offin, MD; Rameshwar, P; Sifri, ZC, 2011) |
| "Propranolol pretreatment blocked macrophage arginase activity induced by epinephrine (10 mumol/L) in vitro (P < ." | 1.31 | Beta adrenoceptor regulation of macrophage arginase activity. ( Arden, WA; Bernard, AC; Boulanger, BR; Fitzpatrick, EA; Gellin, GL; Kearney, PA; Maley, ME; Ochoa, JB; Tsuei, BJ, 2000) |
| "This increased resistance to a lethal trauma in rats conditioned by drummings with concurrent administration of propranolol was confirmed in another lot of rats." | 1.27 | Effect of beta-receptor blockade on the development of resistance to trauma in rats. ( Asoh, T; Shirasaka, C; Takeuchi, Y; Tsuji, H, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Loftus, TJ | 1 |
| Kannan, KB | 1 |
| Mira, JC | 1 |
| Brakenridge, SC | 1 |
| Efron, PA | 1 |
| Mohr, AM | 3 |
| Bible, LE | 1 |
| Pasupuleti, LV | 1 |
| Alzate, WD | 2 |
| Gore, AV | 1 |
| Song, KJ | 1 |
| Sifri, ZC | 2 |
| Livingston, DH | 2 |
| Xu, L | 1 |
| Yu, WK | 1 |
| Lin, ZL | 1 |
| Tan, SJ | 1 |
| Bai, XW | 1 |
| Ding, K | 1 |
| Li, N | 1 |
| Romana-Souza, B | 3 |
| Nascimento, AP | 1 |
| Monte-Alto-Costa, A | 3 |
| Nugent, NR | 1 |
| Christopher, NC | 1 |
| Crow, JP | 1 |
| Browne, L | 1 |
| Ostrowski, S | 1 |
| Delahanty, DL | 1 |
| Porto, LC | 1 |
| Bryant, RA | 1 |
| Baranski, GM | 1 |
| Offin, MD | 1 |
| Elhassan, IO | 1 |
| Hannoush, EJ | 1 |
| Rameshwar, P | 1 |
| Stein, MB | 1 |
| Kerridge, C | 1 |
| Dimsdale, JE | 1 |
| Hoyt, DB | 1 |
| Asoh, T | 1 |
| Tsuji, H | 1 |
| Shirasaka, C | 1 |
| Takeuchi, Y | 1 |
| Tischler, ME | 1 |
| Palma, JA | 1 |
| Enders, J | 1 |
| de Oliva, PP | 1 |
| Bernard, AC | 1 |
| Fitzpatrick, EA | 1 |
| Maley, ME | 1 |
| Gellin, GL | 1 |
| Tsuei, BJ | 1 |
| Arden, WA | 1 |
| Boulanger, BR | 1 |
| Kearney, PA | 1 |
| Ochoa, JB | 1 |
| Vigas, M | 1 |
| Németh, S | 1 |
| Kvetnanský, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Protocol for a Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events Comparing Trauma-informed and Usual Health Care Practice[NCT02299583] | 684 participants (Anticipated) | Interventional | 2014-10-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Injuries
| Article | Year |
|---|---|
Early intervention for post-traumatic stress disorder.
Topics: Cognitive Behavioral Therapy; Humans; Primary Prevention; Propranolol; Randomized Controlled Trials | 2007 |
Hormonal regulation of protein degradation in skeletal and cardiac muscle.
Topics: Adrenalectomy; Alanine; Animals; Corticosterone; Diabetes Mellitus, Experimental; Epinephrine; Fasti | 1981 |
3 trials available for propranolol and Injuries
| Article | Year |
|---|---|
Early propranolol administration to severely injured patients can improve bone marrow dysfunction.
Topics: Adult; Bone Marrow; Female; Heart Rate; Hematopoietic Stem Cell Mobilization; Humans; Injury Severit | 2014 |
The efficacy of early propranolol administration at reducing PTSD symptoms in pediatric injury patients: a pilot study.
Topics: Adolescent; Adrenergic beta-Antagonists; Child; Double-Blind Method; Emergencies; Female; Humans; Li | 2010 |
Pharmacotherapy to prevent PTSD: Results from a randomized controlled proof-of-concept trial in physically injured patients.
Topics: Adolescent; Adult; Amines; Anti-Anxiety Agents; California; Cyclohexanecarboxylic Acids; Female; Gab | 2007 |
10 other studies available for propranolol and Injuries
| Article | Year |
|---|---|
Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress.
Topics: Animals; Clonidine; Corticosterone; Enzyme-Linked Immunosorbent Assay; Hematopoietic Stem Cells; Hep | 2020 |
Impact of β-adrenoceptor blockade on systemic inflammation and coagulation disturbances in rats with acute traumatic coagulopathy.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Blood Coagulation Disorders; Blotting, W | 2015 |
Propranolol improves cutaneous wound healing in streptozotocin-induced diabetic rats.
Topics: Animals; Cell Proliferation; Collagen; Diabetes Mellitus, Experimental; Granulation Tissue; Inflamma | 2009 |
Simultaneous blockade of alpha and beta adrenoceptors impairs cutaneous wound healing in rats.
Topics: Administration, Cutaneous; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cell | 2010 |
Cutaneous wound healing of chronically stressed mice is improved through catecholamines blockade.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Cell Proliferation; Drug Evaluation, Preclinic | 2010 |
β-blockade protection of bone marrow following trauma: the role of G-CSF.
Topics: Adrenergic beta-Antagonists; Anemia; Animals; Bone Marrow; Catecholamines; Contusions; Granulocyte C | 2011 |
Effect of beta-receptor blockade on the development of resistance to trauma in rats.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Male; Propranolol; Rats; Rats, Inbr | 1983 |
Effects of epinephrine on plasma fibrinogen levels in rats submitted to tissue injury.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Epinephrine; Female; Fibrinogen; Laparotomy; Male; Phenoxyb | 1981 |
Beta adrenoceptor regulation of macrophage arginase activity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anima | 2000 |
Lack of effects of adrenergic blockade, adrenal medullectomy and medullectomy combined with reserpine treatment on the metabolic response to injury.
Topics: Adrenal Medulla; Animals; Catecholamines; Ergotamine; Glycogen Storage Disease; Lactates; Liver Glyc | 1973 |