khellin has been researched along with Injuries in 41 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective was to establish the safety and efficacy of intralesional 5-fluorouracil (5-FU) for the treatment of keloids and hypertrophic scars." | 9.30 | Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. ( Ahmad, S; Khalid, FA; Mehrose, MY; Mujahid, AM; Rehman, SU; Saleem, M; Tarar, MN; Yousaf, MA, 2019) |
| "The aim of this study was to investigate the prevalences of hypertrophic scars and keloids in acne patients treated with oral isotretinoin." | 7.83 | Observational retrospective study evaluating the effects of oral isotretinoin in keloids and hypertrophic scars. ( Bagatin, E; Gonçalves, RG; Guadanhim, LR, 2016) |
| " We aimed to compare the efficacy and safety of TAC alone and in combination with 5-FU for the treatment of hypertrophic scars and keloids." | 6.55 | Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis. ( Fan, B; Feng, S; Lin, W; Ren, Y; Wei, Z; Zhou, X, 2017) |
| "Tacrolimus is an immunomodulator that could be useful in treating keloid." | 5.37 | Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis. ( Blondel, WC; Chassagne, JF; Gisquet, H; Guillemin, F; Latarche, C; Leroux, A; Liu, H; Merlin, JL; Peiffert, D, 2011) |
| "The objective was to establish the safety and efficacy of intralesional 5-fluorouracil (5-FU) for the treatment of keloids and hypertrophic scars." | 5.30 | Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. ( Ahmad, S; Khalid, FA; Mehrose, MY; Mujahid, AM; Rehman, SU; Saleem, M; Tarar, MN; Yousaf, MA, 2019) |
| "The aim of this study was to investigate the prevalences of hypertrophic scars and keloids in acne patients treated with oral isotretinoin." | 3.83 | Observational retrospective study evaluating the effects of oral isotretinoin in keloids and hypertrophic scars. ( Bagatin, E; Gonçalves, RG; Guadanhim, LR, 2016) |
| "Therefore, tailor made manipulation of cancer stroma can have important therapeutic consequences." | 2.55 | How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair. ( Fáber, L; Gál, P; Mirossay, A; Mitrengová, P; Mučaji, P; Novák, Š; Smetana, K; Szabo, P; Varinská, L, 2017) |
| " We aimed to compare the efficacy and safety of TAC alone and in combination with 5-FU for the treatment of hypertrophic scars and keloids." | 2.55 | Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis. ( Fan, B; Feng, S; Lin, W; Ren, Y; Wei, Z; Zhou, X, 2017) |
| "Keloid is a benign fibroblastic tumor which is most often secondary to a scar, but it can occur spontaneously in a subject with black skin." | 1.51 | [Giant right post-traumatic retroauricular keloid]. ( Mallé, M; Touré, S, 2019) |
| "Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients." | 1.46 | Keloid progression: a stiffness gap hypothesis. ( Du, Y; Huang, C; Liu, L; Ogawa, R; Wang, B; You, Z, 2017) |
| "Keloid is a benign fibrous growth, which presents in scar tissue of predisposed individuals." | 1.43 | Risk factors of keloids in Syrians. ( Kesh, F; Khaddam, J; Shaheen, A, 2016) |
| "Children accounted for 78." | 1.38 | Plastic and reconstructive surgery in Zambia: epidemiology of 16 years of practice. ( Bowman, KG; Corlew, DS; Jovic, G, 2012) |
| "Tacrolimus is an immunomodulator that could be useful in treating keloid." | 1.37 | Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis. ( Blondel, WC; Chassagne, JF; Gisquet, H; Guillemin, F; Latarche, C; Leroux, A; Liu, H; Merlin, JL; Peiffert, D, 2011) |
| "It is important that scar mechanobiology be understood from the perspective of the extracellular matrix and extracellular fluid, in order to analyze mechanotransduction pathways and develop new strategies for scar prevention and treatment." | 1.37 | Mechanobiology of scarring. ( Ogawa, R, 2011) |
| "Sixteen percent of wounds were repaired with 2-OCA." | 1.31 | Preliminary experience with 2-octylcyanoacrylate in a pediatric emergency department. ( Hick, JL; Resch, KL, 2000) |
| "Ideal conditions for best scarring include: accurate apposition of wound edges; sutures under minimal tension; everted skin edges; placing the wound in 'Langer's lines' or lines of election; adequately supporting the wound; ensuring the wound is free from infection or haematoma." | 1.30 | Scars. Can they be minimised? ( Burke, M, 1998) |
| "A keloid is a pathological overgrowth of scar expanding beyond the boundaries of the initiating skin wound." | 1.29 | Increased proliferation in keloid fibroblasts wounded in vitro. ( Banes, AJ; Calderon, M; Lawrence, WT, 1996) |
| "The results of treatment of keloids are still very disappointing." | 1.25 | Keloids in Ibadan. ( Oluwasanmi, JO, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (46.34) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 5 (12.20) | 29.6817 |
| 2010's | 13 (31.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Touré, S | 1 |
| Mallé, M | 1 |
| Gál, P | 1 |
| Varinská, L | 1 |
| Fáber, L | 1 |
| Novák, Š | 1 |
| Szabo, P | 1 |
| Mitrengová, P | 1 |
| Mirossay, A | 1 |
| Mučaji, P | 1 |
| Smetana, K | 1 |
| Ghazawi, FM | 1 |
| Zargham, R | 1 |
| Gilardino, MS | 1 |
| Sasseville, D | 1 |
| Jafarian, F | 1 |
| Khalid, FA | 1 |
| Mehrose, MY | 1 |
| Saleem, M | 1 |
| Yousaf, MA | 1 |
| Mujahid, AM | 1 |
| Rehman, SU | 1 |
| Ahmad, S | 1 |
| Tarar, MN | 1 |
| DEMJEN, S | 1 |
| Guadanhim, LR | 1 |
| Gonçalves, RG | 1 |
| Bagatin, E | 1 |
| Ren, Y | 1 |
| Zhou, X | 1 |
| Wei, Z | 1 |
| Lin, W | 1 |
| Fan, B | 1 |
| Feng, S | 1 |
| Shaheen, A | 1 |
| Khaddam, J | 1 |
| Kesh, F | 1 |
| Huang, C | 1 |
| Liu, L | 2 |
| You, Z | 1 |
| Wang, B | 1 |
| Du, Y | 1 |
| Ogawa, R | 2 |
| Gisquet, H | 1 |
| Liu, H | 1 |
| Blondel, WC | 1 |
| Leroux, A | 1 |
| Latarche, C | 1 |
| Merlin, JL | 1 |
| Chassagne, JF | 1 |
| Peiffert, D | 1 |
| Guillemin, F | 1 |
| Pistorio, AL | 1 |
| Ehrlich, HP | 1 |
| Jovic, G | 1 |
| Corlew, DS | 1 |
| Bowman, KG | 1 |
| Stollery, N | 1 |
| Deng, WN | 1 |
| Wang, CY | 1 |
| ROBINSON, DW | 1 |
| SCHWARZ, K | 1 |
| KOONIN, AJ | 1 |
| Rekha, A | 1 |
| Robles, DT | 1 |
| Moore, E | 1 |
| Draznin, M | 1 |
| Berg, D | 1 |
| Deitch, EA | 1 |
| Clothier, J | 1 |
| Hunt, TK | 1 |
| Cohen, IK | 1 |
| McCoy, BJ | 1 |
| Lee, CP | 1 |
| Calderon, M | 1 |
| Lawrence, WT | 1 |
| Banes, AJ | 1 |
| Burke, M | 1 |
| Topham, J | 1 |
| Resch, KL | 1 |
| Hick, JL | 1 |
| Valencia, IC | 1 |
| Falabella, AF | 1 |
| Schachner, LA | 1 |
| Gay, B | 1 |
| Doyle, DE | 1 |
| Passey, V | 1 |
| Hazrati, E | 1 |
| Haq, MA | 1 |
| Haq, A | 1 |
| Curth, W | 1 |
| McSorley, J | 1 |
| Oluwasanmi, JO | 2 |
| Haas, E | 1 |
| Leroy, P | 1 |
| Nylén, B | 1 |
| Wåhlin, A | 1 |
| Wright, ET | 1 |
| Haase, KH | 1 |
| Kiesewetter, WB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Post-Surgical Intralesional Injection With Triamcinolone Versus Triamcinolone Plus Fluorouracil in the Treatment of Keloids[NCT04710719] | 7 participants (Actual) | Interventional | 2021-02-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for khellin and Injuries
| Article | Year |
|---|---|
How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair.
Topics: Animals; Cellular Microenvironment; Cytokines; Galectins; Humans; Immune System; Intercellular Signa | 2017 |
Insights into the Pathophysiology of Hypertrophic Scars and Keloids: How Do They Differ?
Topics: Biopsy, Needle; Cicatrix, Hypertrophic; Collagen; Combined Modality Therapy; Diagnosis, Differential | 2018 |
Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Drug Therapy, Combination; Female; Fluorouracil; H | 2017 |
Keloids - a frustrating hurdle in wound healing.
Topics: Combined Modality Therapy; Dermatology; Female; Humans; Keloid; Male; Prognosis; Radiotherapy; Risk | 2004 |
Keloids: pathophysiology and management.
Topics: Adjuvants, Immunologic; Administration, Topical; Animals; Apoptosis; Bandages; Collagen; Cryotherapy | 2007 |
Disorders of wound healing.
Topics: Cicatrix; Collagen; Humans; Hypertrophy; Keloid; Marfan Syndrome; Metabolic Diseases; Wound Healing; | 1980 |
The biology and control of surface overhealing.
Topics: Burns; Cicatrix; Humans; Keloid; Wound Healing; Wounds and Injuries | 1980 |
New developments in wound care for infants and children.
Topics: Child; Drug Eruptions; Extravasation of Diagnostic and Therapeutic Materials; Humans; Infant; Infant | 2001 |
2 trials available for khellin and Injuries
| Article | Year |
|---|---|
Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial.
Topics: Adult; Body Piercing; Burns; Cicatrix, Hypertrophic; Double-Blind Method; Drug Therapy, Combination; | 2019 |
Pressure therapy in treatment of hypertrophic scar, burn contracture and keloid: the Kenyan experience.
Topics: Adolescent; Adult; Bandages; Burns; Child; Child, Preschool; Cicatrix; Clothing; Female; Humans; Hyp | 1990 |
31 other studies available for khellin and Injuries
| Article | Year |
|---|---|
[Giant right post-traumatic retroauricular keloid].
Topics: Biopsy; Dermatofibrosarcoma; Diagnosis, Differential; Ear; Humans; Keloid; Male; Skin Neoplasms; Wou | 2019 |
[Scars and keloids].
Topics: Cicatrix; Humans; Keloid; Wounds and Injuries | 1950 |
Observational retrospective study evaluating the effects of oral isotretinoin in keloids and hypertrophic scars.
Topics: Acne Vulgaris; Administration, Oral; Adolescent; Adult; Case-Control Studies; Cicatrix, Hypertrophic | 2016 |
Risk factors of keloids in Syrians.
Topics: Adolescent; Adult; Age Distribution; Aged; Child; Female; Humans; Incidence; Keloid; Male; Middle Ag | 2016 |
Keloid progression: a stiffness gap hypothesis.
Topics: Elasticity; Humans; Keloid; Skin Diseases; Wound Healing; Wounds and Injuries | 2017 |
Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis.
Topics: Animals; Cicatrix, Hypertrophic; Dermoscopy; Disease Models, Animal; Ear, External; Female; Hypertro | 2011 |
Modulatory effects of connexin-43 expression on gap junction intercellular communications with mast cells and fibroblasts.
Topics: Actins; Animals; Cell Culture Techniques; Connexin 43; Fibroblasts; Fibrosis; Gap Junctions; Gene Ex | 2011 |
Plastic and reconstructive surgery in Zambia: epidemiology of 16 years of practice.
Topics: Adolescent; Adult; Age Distribution; Child; Child, Preschool; Congenital Abnormalities; Developing C | 2012 |
Trauma injuries.
Topics: Air Bags; Atrophy; Burns; Cryotherapy; Glucocorticoids; Humans; Hyphema; Keloid; Skin; Warts; Wounds | 2011 |
Mechanobiology of scarring.
Topics: Animals; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Mechanoreceptors; Models, Animal; Skin; S | 2011 |
[The mast cell and trauma].
Topics: Burns; Forensic Medicine; Fractures, Bone; Humans; Inflammation; Keloid; Mast Cells; Wound Healing; | 2002 |
Hypertrophic scars and keloids.
Topics: Cicatrix; Cicatrix, Hypertrophic; Fibroma; Humans; Keloid; Wounds and Injuries | 1953 |
[Posttraumatic dermatological complications].
Topics: Dermatitis; Humans; Hypersensitivity; Keloid; Radiation Injuries; Wound Healing; Wounds and Injuries | 1962 |
THE AETIOLOGY OF KELOIDS: A REVIEW OF THE LITERATURE AND A NEW HYPOTHESIS.
Topics: Acromegaly; Black People; Cicatrix; Drug Therapy; Foreign Bodies; Humans; Hydrocortisone; Hyperthyro | 1964 |
Burns in the elderly: an early surgical approach.
Topics: Aged; Burns; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; Surgical Procedures, Oper | 1983 |
Keloids--their epidemiology and treatment.
Topics: Adolescent; Adult; Age Factors; Child; Humans; Keloid; Racial Groups; Wound Healing; Wounds and Inju | 1982 |
Increased proliferation in keloid fibroblasts wounded in vitro.
Topics: Autoradiography; Cell Count; Cell Division; Cells, Cultured; Fibroblasts; Humans; Keloid; Thymidine; | 1996 |
Scars. Can they be minimised?
Topics: Ambulatory Surgical Procedures; Bandages; Cicatrix; Cicatrix, Hypertrophic; Dermatologic Surgical Pr | 1998 |
Preventing hypertrophic scarring and keloids.
Topics: Bandages; Humans; Keloid; Skin Care; Wounds and Injuries | 1998 |
Preliminary experience with 2-octylcyanoacrylate in a pediatric emergency department.
Topics: Adolescent; Child; Child, Preschool; Cyanoacrylates; Emergency Treatment; Female; Hematoma; Humans; | 2000 |
[The management of occasional wounds].
Topics: Drainage; First Aid; Hemostasis; Humans; Keloid; Suture Techniques; Tetanus; Tetanus Toxoid; Wounds | 1976 |
Keloid management and its present status.
Topics: Age Factors; Foreign-Body Reaction; Humans; Infections; Keloid; Sex Factors; Steroids, Fluorinated; | 1975 |
[Tissue reactivity and its relation to cancers of the skin].
Topics: Cicatrix; Humans; Keloid; Postoperative Complications; Precancerous Conditions; Radiation Injuries; | 1975 |
Multiple keloids.
Topics: Acne Vulgaris; Adult; Aged; Black or African American; Female; Humans; Keloid; Male; Middle Aged; Sk | 1971 |
Keloids in Ibadan.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Ear, External; Female; Humans; Keloid; Male | 1974 |
[Suture techniques, scars and their correction (author's transl)].
Topics: Cicatrix; Humans; Keloid; Methods; Postoperative Complications; Prednisolone; Surgery, Plastic; Surg | 1974 |
Keloids in the African.
Topics: Adolescent; Adult; Africa; Black People; Child; Child, Preschool; Disease Susceptibility; Endocrine | 1974 |
[The use of benzene adhesives in the closure of wounds].
Topics: Benzene Derivatives; Cicatrix; Humans; Inflammation; Keloid; Surgical Procedures, Operative; Tissue | 1973 |
[Observations from a Saigon hospital for reconstructive pediatric surgery].
Topics: Anesthesiology; Burns; Child; Child Health Services; Humans; Keloid; Mouth Abnormalities; Noma; Preo | 1972 |
Keloids and ultrasound.
Topics: Adult; Biopsy; Burns; Humans; Keloid; Male; Middle Aged; Ultrasonic Therapy; Wounds and Injuries | 1971 |
Gastrointestinal, genitourinary, and wound complications.
Topics: Anuria; Drainage; Gastrointestinal Diseases; Hematuria; Humans; Infant; Infant, Newborn; Intestinal | 1969 |