methoxyflurane has been researched along with Injuries in 14 studies
Methoxyflurane: An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)
methoxyflurane : An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Methoxyflurane AnalGesia for Paediatric InjuriEs (MAGPIE) trial will provide efficacy and safety data for methoxyflurane administered via the Penthrox® inhaler, in children and adolescents who present to EDs with moderate to severe injury-related pain." | 5.30 | Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children-the MAGPIE trial (MEOF-002): study protocol for a randomised controlled trial. ( Barrett, MJ; Hartshorn, S; Irvine, AT; Lyttle, MD; Yee, SA, 2019) |
| " Adverse events (all non-serious) were reported by 17% of methoxyflurane-treated patients and 3% of SAT-treated patients." | 2.90 | Analgesic Efficacy, Practicality and Safety of Inhaled Methoxyflurane Versus Standard Analgesic Treatment for Acute Trauma Pain in the Emergency Setting: A Randomised, Open-Label, Active-Controlled, Multicentre Trial in Italy (MEDITA). ( Bonafede, E; Carpinteri, G; Fabbri, A; Farina, A; Gangitano, G; Intelligente, F; Mercadante, S; Ruggiano, G; Sblendido, A; Serra, S; Soldi, A; Voza, A, 2019) |
| "Methoxyflurane treatment was rated 'Excellent', 'Very Good' or 'Good' by 77." | 2.82 | Methoxyflurane Analgesia in Adult Patients in the Emergency Department: A Subgroup Analysis of a Randomized, Double-blind, Placebo-controlled Study (STOP!). ( Coffey, F; Dissmann, P; Lomax, M; Mirza, K, 2016) |
| "Adult patients with moderate to severe trauma pain and Glasgow coma score of 15 were included in the evaluation." | 1.56 | Service Evaluation of Methoxyflurane Versus Standard Care for Overall Management of Patients with Pain Due to Injury. ( Bailey, GP; McKinlay, JAC; Young, L, 2020) |
| "Acute trauma pain is poorly managed in the emergency department (ED)." | 1.56 | Multiple criteria decision analysis approach to consider therapeutic innovations in the emergency department: The methoxyflurane organizational impact in acute trauma pain. ( Diallo, ML; Dussart, C; Hadjadj-Baillot, C; Lapostolle, F; Lvovschi, VE; Maignan, M; Pons-Kerjean, N; Tazarourte, K, 2020) |
| "Adult non-severe trauma patients with a numerical pain rating scale (NRS) score ≥ 4 were included." | 1.51 | Multimodal oral analgesia for non-severe trauma patients: evaluation of a triage-nurse directed protocol combining methoxyflurane, paracetamol and oxycodone. ( Champel, F; Collomb Muret, R; Falcon, C; Mabiala Makele, P; Maignan, M; Maindet Dominici, C; Mouthon, A; Termoz Masson, N; Verdetti, A; Viglino, D, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Mercadante, S | 1 |
| Voza, A | 1 |
| Serra, S | 1 |
| Ruggiano, G | 1 |
| Carpinteri, G | 1 |
| Gangitano, G | 1 |
| Intelligente, F | 1 |
| Bonafede, E | 1 |
| Sblendido, A | 2 |
| Farina, A | 2 |
| Soldi, A | 2 |
| Fabbri, A | 1 |
| Borobia, AM | 1 |
| Collado, SG | 1 |
| Cardona, CC | 1 |
| Pueyo, RC | 1 |
| Alonso, CF | 1 |
| Torres, IP | 1 |
| González, MC | 1 |
| Casal Codesido, JR | 1 |
| Betegón, MA | 1 |
| Barcela, LA | 1 |
| Andicoechea, AO | 1 |
| Testa, AF | 1 |
| Colina, JT | 1 |
| Dorribo, AC | 1 |
| Del Arco Galán, C | 1 |
| Martínez Ávila, JC | 1 |
| Lugilde, ST | 1 |
| Carcas Sansuán, AJ | 1 |
| Young, L | 1 |
| Bailey, GP | 1 |
| McKinlay, JAC | 1 |
| Lvovschi, VE | 1 |
| Maignan, M | 2 |
| Tazarourte, K | 1 |
| Diallo, ML | 1 |
| Hadjadj-Baillot, C | 1 |
| Pons-Kerjean, N | 1 |
| Lapostolle, F | 1 |
| Dussart, C | 1 |
| Marinangeli, F | 1 |
| Reggiardo, G | 1 |
| Hartshorn, S | 1 |
| Barrett, MJ | 1 |
| Lyttle, MD | 1 |
| Yee, SA | 1 |
| Irvine, AT | 1 |
| Viglino, D | 1 |
| Termoz Masson, N | 1 |
| Verdetti, A | 1 |
| Champel, F | 1 |
| Falcon, C | 1 |
| Mouthon, A | 1 |
| Mabiala Makele, P | 1 |
| Collomb Muret, R | 1 |
| Maindet Dominici, C | 1 |
| Coffey, F | 1 |
| Dissmann, P | 1 |
| Mirza, K | 1 |
| Lomax, M | 1 |
| Boĭko, VV | 1 |
| Sushkov, SV | 1 |
| Zamiatin, PN | 1 |
| Krut'ko, EN | 1 |
| BAEZ, S | 1 |
| ORKIN, LR | 1 |
| AUBERGER, H | 1 |
| HILSCHENZ, I | 1 |
| Poliakov, VV | 1 |
| Zaugol'nikov, VS | 1 |
| Tsybuliak, GN | 1 |
| Cuesta Bianchi, A | 1 |
| López Rodríguez, F | 1 |
| Delfino, U | 1 |
| Nadali, L | 1 |
| Pattono, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Methoxyflurane Vaporized (PENTHROX®) in the Treatment of Acute Trauma Pain in Pre-hospital Setting and in the Emergency Department in Italy: a Multicentre, Randomized, Controlled, Open-label Study[NCT03585374] | Phase 3 | 272 participants (Actual) | Interventional | 2018-02-08 | Completed | ||
| Open Randomized Clinical Trial to Compare Pain Relief Between Methoxyflurane and Standard of Care for Treating Patients With Trauma Pain in Spanish Emergency Units.[NCT03256903] | Phase 3 | 310 participants (Actual) | Interventional | 2017-07-07 | Completed | ||
| A Randomised, Double-blind, Multicentre, Placebo Controlled Study to Evaluate the Safety and Efficacy of Methoxyflurane (PENTHROX®) for the Treatment of Acute Pain in Children and Adolescents From 6 to Less Than 18 Years of Age (Presenting to an Emergency[NCT03215056] | Phase 3 | 222 participants (Anticipated) | Interventional | 2017-06-30 | Recruiting | ||
| Multimodal Oral Analgesia for Trauma in the Emergency Department: a Prospective Observational Study of a Nurse-directed Protocol[NCT03380247] | 200 participants (Actual) | Observational | 2017-10-12 | Completed | |||
| A Randomised, Double Blind, Multi-centre, Placebo Controlled Study to Evaluate the Efficacy and Safety of Methoxyflurane (Penthrox) for the Treatment of Acute Pain in Patients Presenting to an Emergency Department With Minor Trauma[NCT01420159] | Phase 3 | 300 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for methoxyflurane and Injuries
9 other studies available for methoxyflurane and Injuries
| Article | Year |
|---|---|
Service Evaluation of Methoxyflurane Versus Standard Care for Overall Management of Patients with Pain Due to Injury.
Topics: Acute Pain; Adult; Anesthetics, Inhalation; Emergency Service, Hospital; Female; Glasgow Coma Scale; | 2020 |
Multiple criteria decision analysis approach to consider therapeutic innovations in the emergency department: The methoxyflurane organizational impact in acute trauma pain.
Topics: Acute Pain; Anesthetics, Inhalation; Clinical Decision-Making; Critical Pathways; Crowding; Decision | 2020 |
Multimodal oral analgesia for non-severe trauma patients: evaluation of a triage-nurse directed protocol combining methoxyflurane, paracetamol and oxycodone.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Emergency Service, Hospital; Female; France; | 2019 |
[Application of penthrox preparation in patients with traumatic disease].
Topics: Administration, Inhalation; Analgesics; Humans; Methoxyflurane; Pain; Pain Measurement; Treatment Ou | 2011 |
MICROCIRCULATORY EFFECTS OF ANESTHESIA IN SHOCK.
Topics: Anesthesia; Blood Circulation; Blood Pressure; Capillaries; Cyclopropanes; Ether; Halothane; Hematoc | 1964 |
[EXPERIENCES WITH THE INHALATION ANESTHETIC METHOXYFLURANE IN SURGICAL ORTHOPEDICS].
Topics: Adolescent; Anesthesia; Anesthesia, Inhalation; Anesthesiology; Anesthetics, Inhalation; Child; Geri | 1964 |
[Methoxyflurane (Inhalane) anesthesia in injuries at the prehospital stage].
Topics: Adolescent; Adult; Aged; Analgesia; Anesthesia, Inhalation; Female; Humans; Male; Methoxyflurane; Mi | 1972 |
[Methoxyflurane in orthopedic and traumatic surgery].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Bone and Bones; Child; Child, Preschool; Humans; Metho | 1970 |
[Our considerations on the use of penthrane in orthopedic surgery and traumatology].
Topics: Adolescent; Adult; Aged; Anesthesia; Child; Female; Humans; Male; Methoxyflurane; Middle Aged; Ortho | 1967 |