lidocaine has been researched along with Injuries in 75 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical 2% lidocaine does not attenuate the pain of infiltration of buffered lidocaine more than does topical normal saline." | 9.08 | Does topical lidocaine attenuate the pain of infiltration of buffered lidocaine? ( Bartfield, JM; Raccio-Robak, N; Salluzzo, RF, 1995) |
| "The results of the treatment of 36 patients with posttraumatic reflex sympathetic dystrophy of the upper extremity with regional intravenous blocks of methylprednisolone and lidocaine are presented." | 9.08 | Results of the treatment of posttraumatic reflex sympathetic dystrophy of the upper extremity with regional intravenous blocks of methylprednisolone and lidocaine. ( Zyluk, A, 1998) |
| " However, with lidocaine there was a significant plasma concentration-dependent decrease in pain scores starting at 1." | 9.08 | Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury. ( Dyck, BJ; Rossi, SS; Wallace, MS; Yaksh, TL, 1996) |
| "Lidocaine hydrochloride is frequently used for management of painful wounds." | 8.12 | 5% Lidocaine Hydrochloride Cream for Wound Pain Relief: A Multicentre Observational Study. ( Arnez, ZM; Davini, G; Dini, V; Janowska, A; Oranges, T; Papa, G; Romanelli, M; Stocco, C, 2022) |
| " Our aim was to examine the effect of two different analgesics, buprenorphine and carprofen, on adenosine, lidocaine, and magnesium (ALM) resuscitation in a rat model of laparotomy and non-compressible hemorrhage." | 8.02 | Buprenorphine Analgesia Reduces Survival With ALM Resuscitation in a Rat Model of Uncontrolled Hemorrhage: Concerns for Trauma-Related Research. ( Dobson, GP; Letson, HL, 2021) |
| "Adenosine, lidocaine, and magnesium, as administered in this study, are inferior to current Hextend-based resuscitation for survival from prolonged hemorrhagic shock in this model." | 7.91 | Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock. ( Cardin, S; Fryer, DM; Glaser, JJ; How, RA; Morgan, CG; Ozuna, KM; Sams, VG; Schaub, LJ, 2019) |
| "Intracellular calcium, cytoskeleton remodelling, and cell migration were assessed in vitro in MDA-MB-231 cells, a human breast cancer epithelial cell line, after exposure to lidocaine (10 μM or 100 μM)." | 7.88 | Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration. ( Anselmi, L; Borgeat, A; Cecchinato, V; D'Agostino, G; Saporito, A; Silvestri, Y; Uguccioni, M, 2018) |
| "The prognostic value of a dynamic liver-function test, based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX), in predicting multiple organ failure (MOF) was prospectively investigated in 28 critically ill patients after multiple trauma." | 7.69 | Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure. ( Armstrong, VW; Lehmann, U; Oellerich, M; Pape, D; Regel, G; Schütz, E, 1995) |
| " Controlling for pre-VAC change pain, the lidocaine intervention was associated with 2." | 5.17 | Lidocaine analgesia for removal of wound vacuum-assisted closure dressings: a randomized double-blinded placebo-controlled trial. ( Christensen, TJ; Kubiak, EN; Thorum, T, 2013) |
| "A topical lidocaine patch is effective in the treatment of posttraumatic peripheral neuropathy (PTPN), but it is not suited for breakthrough pain because of difficulty with an additional application." | 5.14 | The analgesic effect of a metered-dose 8% lidocaine pump spray in posttraumatic peripheral neuropathy: a pilot study. ( Kanai, A; Koto, M; Okamoto, H; Okamoto, T; Segawa, Y, 2009) |
| "Topical 2% lidocaine does not attenuate the pain of infiltration of buffered lidocaine more than does topical normal saline." | 5.08 | Does topical lidocaine attenuate the pain of infiltration of buffered lidocaine? ( Bartfield, JM; Raccio-Robak, N; Salluzzo, RF, 1995) |
| "The results of the treatment of 36 patients with posttraumatic reflex sympathetic dystrophy of the upper extremity with regional intravenous blocks of methylprednisolone and lidocaine are presented." | 5.08 | Results of the treatment of posttraumatic reflex sympathetic dystrophy of the upper extremity with regional intravenous blocks of methylprednisolone and lidocaine. ( Zyluk, A, 1998) |
| " However, with lidocaine there was a significant plasma concentration-dependent decrease in pain scores starting at 1." | 5.08 | Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury. ( Dyck, BJ; Rossi, SS; Wallace, MS; Yaksh, TL, 1996) |
| "3 mg/kg) and buffered lidocaine in reducing the anxiety associated with the repair of childhood lacerations." | 5.08 | A randomized, controlled trial of oral midazolam and buffered lidocaine for suturing lacerations in children (the SLIC Trial). ( Fatovich, DM; Jacobs, IG, 1995) |
| "Analysis of pooled data and paired data (using patients as their own controls) revealed that infiltrating buffered lidocaine was significantly less painful than plain lidocaine (P = ." | 5.06 | Buffered versus plain lidocaine as a local anesthetic for simple laceration repair. ( Barbera, J; Bartfield, JM; Breuer, B; Gallagher, EJ; Gennis, P, 1990) |
| "Lidocaine hydrochloride is frequently used for management of painful wounds." | 4.12 | 5% Lidocaine Hydrochloride Cream for Wound Pain Relief: A Multicentre Observational Study. ( Arnez, ZM; Davini, G; Dini, V; Janowska, A; Oranges, T; Papa, G; Romanelli, M; Stocco, C, 2022) |
| " Our aim was to examine the effect of two different analgesics, buprenorphine and carprofen, on adenosine, lidocaine, and magnesium (ALM) resuscitation in a rat model of laparotomy and non-compressible hemorrhage." | 4.02 | Buprenorphine Analgesia Reduces Survival With ALM Resuscitation in a Rat Model of Uncontrolled Hemorrhage: Concerns for Trauma-Related Research. ( Dobson, GP; Letson, HL, 2021) |
| "Adenosine, lidocaine, and magnesium, as administered in this study, are inferior to current Hextend-based resuscitation for survival from prolonged hemorrhagic shock in this model." | 3.91 | Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock. ( Cardin, S; Fryer, DM; Glaser, JJ; How, RA; Morgan, CG; Ozuna, KM; Sams, VG; Schaub, LJ, 2019) |
| "Intracellular calcium, cytoskeleton remodelling, and cell migration were assessed in vitro in MDA-MB-231 cells, a human breast cancer epithelial cell line, after exposure to lidocaine (10 μM or 100 μM)." | 3.88 | Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration. ( Anselmi, L; Borgeat, A; Cecchinato, V; D'Agostino, G; Saporito, A; Silvestri, Y; Uguccioni, M, 2018) |
| "The study concludes that lidocaine reduced pain during castration and that meloxicam reduced pain after castration." | 3.77 | Effect of local anaesthesia and/or analgesia on pain responses induced by piglet castration. ( Hansson, M; Johansson, G; Lundeheim, N; Nyman, G, 2011) |
| " We proposed that the introduction of a topical anaesthetic gel (lidocaine, adrenaline, tetracaine - LAT) might help to reduce the number of referrals, by allowing the ED staff to perform the procedures, in combination with nonpharmacological approaches." | 3.76 | Topical anaesthesia in children: reducing the need for specialty referral. ( Mullarkey, C; O'Connor, G, 2010) |
| "One hundred twelve patients with posttraumatic reflex sympathetic dystrophy were treated using 4 methods: regional intravenous blocks with lignocaine and methylprednisolone, mannitol i." | 3.70 | The reasons for poor response to treatment of posttraumatic reflex sympathetic dystrophy. ( Zyluk, A, 1998) |
| "The prognostic value of a dynamic liver-function test, based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX), in predicting multiple organ failure (MOF) was prospectively investigated in 28 critically ill patients after multiple trauma." | 3.69 | Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure. ( Armstrong, VW; Lehmann, U; Oellerich, M; Pape, D; Regel, G; Schütz, E, 1995) |
| "This post-operative/post-traumatic neuropathic chronic cutaneous pain (PNCCP) may be a side-effect of any incision of the skin in the context of a surgical procedure or a traumatic event." | 2.74 | Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases. ( Hans, G; Joukes, E; Vercauteren, M; Verhulst, J, 2009) |
| "Primary hyperalgesia was quantified by determining mechanical (von Frey hairs) and thermal (Peltier thermode) pain thresholds." | 2.69 | Effect of pre- or post-traumatically applied i.v. lidocaine on primary and secondary hyperalgesia after experimental heat trauma in humans. ( Holthusen, H; Irsfeld, S; Lipfert, P, 2000) |
| " Physicians must adhere to recommendations to avoid mucous membrane contact and ensure appropriate dosing with these agents." | 2.40 | Topical anesthesia. ( Keyes, PD; Rizos, J; Tallon, JM, 1998) |
| " In addition to changing serum drug concentration/response relationships, the pharmacokinetic behavior of drugs bound to alpha 1-acid glycoprotein should also change." | 2.37 | Hepatic drug clearance following traumatic injury. ( Hassett, JM; Slaughter, RL, 1985) |
| "Topical application of lidocaine in wounds has been studied in combination with vasoconstrictive additives, but the effect without these additives is unknown." | 1.43 | Anesthesia with topical lidocaine hydrochloride gauzes in acute traumatic wounds in triage, a pilot study. ( Goddijn, H; Goslings, JC; Hollmann, MW; Leenders, N; Lirk, P; Ridderikhof, ML; Schep, NW, 2016) |
| "Lidocaine and phenol were injected into the sciatic nerves of the rats in Groups 1 and 2, respectively." | 1.32 | Free radical-induced damage in experimental peripheral nerve injection injury. ( Apan, A; Kisa, U; Saray, A, 2003) |
| "the day of trauma in most elderly, whereas minor changes were observed in the young." | 1.31 | MEGX disposition in critically-ill trauma patients: subsequent assessments during the first week following trauma. ( Baldassarre, M; Furlanut, M; Licari, M; Pea, F, 2002) |
| "The infection rates of wounds anesthetized with plain lidocaine versus buffered lidocaine were compared in an observational cohort study." | 1.30 | Comparison of wound infection rates using plain versus buffered lidocaine for anesthesia of traumatic wounds. ( Brogan, GX; Giarrusso, E; Hollander, JE; Singer, AJ; Thode, HC; Valentine, SM, 1997) |
| "Clonidine was more potent in CCI then in CFA rats in reducing the response to cold." | 1.30 | The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models. ( Franssen, M; Goff, JR; Janni, G; Jasmin, L; Kohan, L, 1998) |
| "To study the pharmacokinetic parameters of morphine and lidocaine after a single intravenous (i." | 1.30 | The pharmacokinetics of morphine and lidocaine in nine severe trauma patients. ( Almog, S; Berkenstadt, H; Ezra, D; Mayan, H; Perel, A; Rotenberg, M; Segal, E, 1999) |
| "Lidocaine was added to all serum samples from four of the patients and to selected samples from all of the healthy subjects and protein binding was determined." | 1.26 | Alpha1-acid glycoprotein concentration and protein binding in trauma. ( Cerra, F; Edwards, DJ; Lalka, D; Slaughter, RL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (30.67) | 18.7374 |
| 1990's | 27 (36.00) | 18.2507 |
| 2000's | 15 (20.00) | 29.6817 |
| 2010's | 8 (10.67) | 24.3611 |
| 2020's | 2 (2.67) | 2.80 |
| Authors | Studies |
|---|---|
| Letson, HL | 1 |
| Dobson, GP | 1 |
| Janowska, A | 1 |
| Papa, G | 1 |
| Romanelli, M | 1 |
| Davini, G | 1 |
| Oranges, T | 1 |
| Stocco, C | 1 |
| Arnez, ZM | 1 |
| Dini, V | 1 |
| D'Agostino, G | 1 |
| Saporito, A | 1 |
| Cecchinato, V | 1 |
| Silvestri, Y | 1 |
| Borgeat, A | 1 |
| Anselmi, L | 1 |
| Uguccioni, M | 1 |
| Li, X | 1 |
| Wang, C | 1 |
| Yang, S | 1 |
| Liu, P | 1 |
| Zhang, B | 1 |
| How, RA | 1 |
| Glaser, JJ | 1 |
| Schaub, LJ | 1 |
| Fryer, DM | 1 |
| Ozuna, KM | 1 |
| Morgan, CG | 1 |
| Sams, VG | 1 |
| Cardin, S | 1 |
| Azizkhani, R | 1 |
| Forghani, M | 1 |
| Maghami-Mehr, A | 1 |
| Masomi, B | 1 |
| Ridderikhof, ML | 1 |
| Leenders, N | 1 |
| Goddijn, H | 1 |
| Schep, NW | 1 |
| Lirk, P | 1 |
| Goslings, JC | 1 |
| Hollmann, MW | 1 |
| Kanai, A | 1 |
| Segawa, Y | 1 |
| Okamoto, T | 1 |
| Koto, M | 1 |
| Okamoto, H | 1 |
| O'Connor, G | 1 |
| Mullarkey, C | 1 |
| Hans, G | 1 |
| Joukes, E | 1 |
| Verhulst, J | 1 |
| Vercauteren, M | 1 |
| Hansson, M | 1 |
| Lundeheim, N | 1 |
| Nyman, G | 1 |
| Johansson, G | 1 |
| Christensen, TJ | 1 |
| Thorum, T | 1 |
| Kubiak, EN | 1 |
| Pea, F | 1 |
| Licari, M | 1 |
| Baldassarre, M | 1 |
| Furlanut, M | 1 |
| Green, SM | 2 |
| EDDY, DD | 2 |
| ASCHHEIM, E | 2 |
| FARBER, EM | 2 |
| PATMAN, RD | 2 |
| POULOS, E | 1 |
| SHIRES, GT | 1 |
| CORNAGLIA, C | 1 |
| DANIELI, GG | 1 |
| VERNONI, S | 1 |
| ZIPERMAN, HH | 1 |
| MCGINTY, JB | 1 |
| ROTH, RJ | 1 |
| EPINETTE, WW | 1 |
| MONTY, CP | 1 |
| DELLER, CR | 1 |
| Saray, A | 1 |
| Apan, A | 1 |
| Kisa, U | 1 |
| Fowler, E | 2 |
| Mert, T | 1 |
| Daglioglu, YK | 1 |
| Gunay, I | 1 |
| Gocmen, C | 1 |
| Kawasaki, T | 1 |
| Choudhry, MA | 1 |
| Schwacha, MG | 1 |
| Bland, KI | 1 |
| Chaudry, IH | 1 |
| Forde, G | 1 |
| Lundborg, G | 1 |
| Björkman, A | 1 |
| Rosén, B | 1 |
| Holovics, HJ | 1 |
| Anderson, CR | 1 |
| Levine, BS | 1 |
| Hui, HW | 1 |
| Lunte, CE | 1 |
| Hewitt, CE | 1 |
| Mitchell, N | 1 |
| Torgerson, DJ | 1 |
| Elvin, AT | 1 |
| Axelson, JE | 1 |
| Lalka, D | 2 |
| Edwards, DJ | 1 |
| Cerra, F | 1 |
| Slaughter, RL | 2 |
| Bartfield, JM | 3 |
| Raccio-Robak, N | 2 |
| Salluzzo, RF | 1 |
| Lehmann, U | 1 |
| Armstrong, VW | 1 |
| Schütz, E | 1 |
| Regel, G | 1 |
| Pape, D | 1 |
| Oellerich, M | 1 |
| Blackburn, PA | 1 |
| Butler, KH | 1 |
| Hughes, MJ | 1 |
| Clark, MR | 1 |
| Riker, RL | 1 |
| Schilling, CG | 1 |
| Bank, DE | 1 |
| Borchert, BA | 1 |
| Klatzko, MD | 1 |
| Uden, DL | 1 |
| Fatovich, DM | 1 |
| Jacobs, IG | 1 |
| Kendall, JM | 1 |
| Charters, A | 1 |
| McCabe, SE | 1 |
| Ernst, AA | 1 |
| Marvez-Valls, E | 1 |
| Nick, TG | 1 |
| Wahle, M | 1 |
| Wallace, MS | 1 |
| Dyck, BJ | 1 |
| Rossi, SS | 1 |
| Yaksh, TL | 1 |
| Morisaki, H | 1 |
| Masuda, J | 1 |
| Fukushima, K | 1 |
| Iwao, Y | 1 |
| Suzuki, K | 1 |
| Matsushima, M | 1 |
| Eriksson, AS | 1 |
| Sinclair, R | 1 |
| Brogan, GX | 1 |
| Singer, AJ | 1 |
| Valentine, SM | 1 |
| Thode, HC | 1 |
| Giarrusso, E | 1 |
| Hollander, JE | 1 |
| Nathan, B | 1 |
| McKeever, J | 1 |
| Smith, GA | 1 |
| Strausbaugh, SD | 1 |
| Harbeck-Weber, C | 1 |
| Cohen, DM | 1 |
| Shields, BJ | 1 |
| Powers, JD | 1 |
| Denkler, K | 1 |
| Sokaris, SJ | 1 |
| Adler, AJ | 1 |
| Dubinisky, I | 1 |
| Eisen, J | 1 |
| Jasmin, L | 1 |
| Kohan, L | 1 |
| Franssen, M | 1 |
| Janni, G | 1 |
| Goff, JR | 1 |
| Keyes, PD | 1 |
| Tallon, JM | 1 |
| Rizos, J | 1 |
| Zyluk, A | 2 |
| Resch, K | 1 |
| Schilling, C | 1 |
| Borchert, BD | 1 |
| Klatzko, M | 1 |
| Uden, D | 1 |
| Quinlan, K | 1 |
| Berkenstadt, H | 1 |
| Mayan, H | 1 |
| Segal, E | 1 |
| Rotenberg, M | 1 |
| Almog, S | 1 |
| Perel, A | 1 |
| Ezra, D | 1 |
| Holthusen, H | 1 |
| Irsfeld, S | 1 |
| Lipfert, P | 1 |
| Hawkins, JA | 1 |
| Mathewson, HS | 1 |
| Nakayama, DK | 1 |
| Waggoner, T | 1 |
| Venkataraman, ST | 1 |
| Gardner, M | 1 |
| Lynch, JM | 1 |
| Orr, RA | 1 |
| Zhu, ZX | 1 |
| Zhang, YJ | 1 |
| Wang, TJ | 1 |
| Want, Y | 1 |
| Liu, XY | 1 |
| Anderson, AB | 1 |
| Colecchi, C | 1 |
| Baronoski, R | 1 |
| DeWitt, TG | 1 |
| Gennis, P | 1 |
| Barbera, J | 1 |
| Breuer, B | 1 |
| Gallagher, EJ | 1 |
| Spivey, WH | 1 |
| McNamara, RM | 1 |
| MacKenzie, RS | 1 |
| Bhat, S | 1 |
| Burdick, WP | 1 |
| Driuk, NF | 1 |
| Keĭsevich, LV | 1 |
| Kaban, AP | 1 |
| Proleev, AV | 1 |
| Kostrub, AA | 1 |
| Baumgardner, DJ | 1 |
| Hassett, JM | 1 |
| Thompson, JE | 1 |
| Persson, AV | 1 |
| Brooks, JB | 1 |
| Kellogg, DS | 1 |
| Alley, CC | 1 |
| Short, HB | 1 |
| Handsfield, HH | 1 |
| Huff, B | 1 |
| Schlag, G | 1 |
| Miller, RD | 1 |
| Way, WL | 1 |
| Sportelli, S | 1 |
| Garelli, R | 1 |
| Solini, A | 1 |
| Gostishchev, VK | 1 |
| Tolstykh, PI | 1 |
| Kukufaté, EA | 1 |
| Doutre, LP | 1 |
| Périssat, J | 1 |
| Giddon, DB | 1 |
| Lindhe, J | 1 |
| Karczewski, J | 1 |
| Ginal, M | 1 |
| Croce, V | 1 |
| Marino, F | 1 |
| Scaraglio, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Lidocaine Patch for Lower Limb Amputation Pain[NCT02696720] | Phase 2 | 0 participants (Actual) | Interventional | 2016-05-13 | Withdrawn (stopped due to Lack of recruitment) | ||
| Lidocaine Analgesia For Removal Of Wound Vacuum Assisted Closure Dressings: A Randomized Double Blinded Controlled Trial[NCT01126359] | 11 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain : A Pilot Study[NCT02217267] | Phase 3 | 29 participants (Actual) | Interventional | 2014-08-01 | Completed | ||
| Saline Injection - Assisted Anesthesia in Eyelid Surgery[NCT01239498] | Phase 4 | 60 participants (Anticipated) | Interventional | 2010-11-30 | Recruiting | ||
| Optimal Lidocaine Buffering to Reduce Injection Pain in Local Anesthesia[NCT02647892] | Phase 4 | 70 participants (Actual) | Interventional | 2016-01-08 | Terminated (stopped due to IRB protocol administratively closed, Continuing Review or Study Completion Report not submitted) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient break-through narcotic requirements in morphine equivalents are 0.2 mg of dilaudid = 1 mg of morphine, iv., used during and after VAC dressing change. (NCT01126359)
Timeframe: 20 minutes
| Intervention | Narcotic Requirements (mg) (Mean) | |||
|---|---|---|---|---|
| During VAC change | 5 min post-VAC change | 10 min post VAC change | 20 min post VAC change | |
| Lidocaine | 1.3 | 0.8 | 0.2 | 0.0 |
| Lidocaine Minus Placebo-Saline Difference | -1.7 | -0.4 | -0.2 | -0.3 |
| Placebo-Saline | 3.0 | 1.1 | 0.4 | 0.3 |
Visial Analog Pain Scores (VAS) range from 0 (no pain) - 10 (worst pain ever). Visial Analog Pain Scores are determined at each pain measurement time point (during/after VAC dressing removal). (NCT01126359)
Timeframe: 20 minutes
| Intervention | Visial Analog Pain Score (VAS) (Mean) | |||
|---|---|---|---|---|
| During VAC change | 5 min post-VAC change | 10 min post VAC change | 20 min post VAC change | |
| Lidocaine | 6.5 | 4.4 | 3.2 | 2.4 |
| Lidocaine Minus Placebo-Saline Difference | -2.4 | -2.0 | -1.5 | -1.8 |
| Placebo-Saline | 8.9 | 6.4 | 4.7 | 4.2 |
4 reviews available for lidocaine and Injuries
| Article | Year |
|---|---|
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles.
Topics: Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents; Arthritis; | 2007 |
What is the role of diphenhydramine in local anesthesia?
Topics: Anesthesia, Local; Anesthetics, Local; Diphenhydramine; Drug Hypersensitivity; Emergency Medical Ser | 1996 |
Topical anesthesia.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Child; Cocaine; Drug Combinations; Epinephrine; Hu | 1998 |
Hepatic drug clearance following traumatic injury.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Humans; Kinetics; Lidocaine; Liver; Liver Circula | 1985 |
21 trials available for lidocaine and Injuries
| Article | Year |
|---|---|
The analgesic effect of a metered-dose 8% lidocaine pump spray in posttraumatic peripheral neuropathy: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; | 2009 |
Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases.
Topics: Administration, Cutaneous; Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Lidocaine; | 2009 |
Lidocaine analgesia for removal of wound vacuum-assisted closure dressings: a randomized double-blinded placebo-controlled trial.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Cross-Over Studies; Device Removal; | 2013 |
Enhanced sensory relearning after nerve repair by using repeated forearm anaesthesia: aspects on time dynamics of treatment.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Follow-Up Studies; | 2007 |
Does topical lidocaine attenuate the pain of infiltration of buffered lidocaine?
Topics: Administration, Cutaneous; Adolescent; Adult; Anesthesia, Local; Double-Blind Method; Emergencies; F | 1995 |
Comparison of tetracaine-adrenaline-cocaine (TAC) with topical lidocaine-epinephrine (TLE): efficacy and cost.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Cocaine; Cost Savings; Double-Blind | 1995 |
Tetracaine, epinephrine (adrenalin), and cocaine (TAC) versus lidocaine, epinephrine, and tetracaine (LET) for anesthesia of lacerations in children.
Topics: Adolescent; Anesthesia, Local; Child; Child, Preschool; Cocaine; Double-Blind Method; Drug Combinati | 1995 |
A randomized, controlled trial of oral midazolam and buffered lidocaine for suturing lacerations in children (the SLIC Trial).
Topics: Administration, Oral; Anesthesia, Local; Anxiety; Buffers; Child; Child, Preschool; Double-Blind Met | 1995 |
Topical anaesthesia for children's lacerations: an acceptable approach?
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Cocaine; Drug Comb | 1996 |
Comparison trial of four injectable anesthetics for laceration repair.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Diphenhydramine; Double-Blind Method; Drug Therapy, Co | 1996 |
Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury.
Topics: Adult; Aged; Computers; Humans; Infusion Pumps; Lidocaine; Middle Aged; Pain; Pain Measurement; Pain | 1996 |
Wound infiltration with lidocaine prolongs postoperative analgesia after haemorrhoidectomy with spinal anaesthesia.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Hemorrhoids; Humans; Lidocaine; Male; Middle | 1996 |
New non-cocaine-containing topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; C | 1997 |
Local anesthesia for lacerations: pain of infiltration inside vs outside the wound.
Topics: Adult; Anesthetics, Local; Buffers; Female; Humans; Injections, Intralesional; Lidocaine; Male; Pain | 1998 |
Does the use of topical lidocaine, epinephrine, and tetracaine solution provide sufficient anesthesia for laceration repair?
Topics: Adult; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; Epinephrin | 1998 |
Topical anesthesia for pediatric lacerations: a randomized trial of lidocaine-epinephrine-tetracaine solution versus gel.
Topics: Age Factors; Anesthetics, Combined; Anesthetics, Local; Chemistry, Pharmaceutical; Child; Epinephrin | 1998 |
Results of the treatment of posttraumatic reflex sympathetic dystrophy of the upper extremity with regional intravenous blocks of methylprednisolone and lidocaine.
Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Female; Heparin; Humans; Infusions, Intra | 1998 |
Effect of pre- or post-traumatically applied i.v. lidocaine on primary and secondary hyperalgesia after experimental heat trauma in humans.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Burns; Cross-Over Studies; Double-Blind Method; Hot | 2000 |
Local anesthesia in pediatric patients: topical TAC versus lidocaine.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Double-B | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Buffers; Double-Blind Method; Emergencies; Femal | 1990 |
A clinical comparison of lidocaine and bupivacaine.
Topics: Adult; Bupivacaine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Emergencies; Fem | 1987 |
50 other studies available for lidocaine and Injuries
| Article | Year |
|---|---|
Buprenorphine Analgesia Reduces Survival With ALM Resuscitation in a Rat Model of Uncontrolled Hemorrhage: Concerns for Trauma-Related Research.
Topics: Adenosine; Analgesia; Analgesics, Opioid; Animals; Biomedical Research; Buprenorphine; Disease Model | 2021 |
5% Lidocaine Hydrochloride Cream for Wound Pain Relief: A Multicentre Observational Study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Hum | 2022 |
Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration.
Topics: Anesthetics, Local; Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Ch | 2018 |
Electrospun PCL/mupirocin and chitosan/lidocaine hydrochloride multifunctional double layer nanofibrous scaffolds for wound dressing applications.
Topics: Anti-Bacterial Agents; Bacteria; Bandages; Cell Death; Chitosan; Drug Liberation; Fibroblasts; Human | 2018 |
Prehospital adenosine, lidocaine, and magnesium has inferior survival compared with tactical combat casualty care resuscitation in a porcine model of prolonged hemorrhagic shock.
Topics: Adenosine; Animals; Cardioplegic Solutions; Disease Models, Animal; Emergency Medical Services; Lido | 2019 |
The effects of injections of warmed bicarbonate-buffered Lidocaine as a painkiller for patients with trauma.
Topics: Analgesics; Anesthetics, Local; Bicarbonates; Buffers; Hot Temperature; Humans; Injections, Intrader | 2015 |
Anesthesia with topical lidocaine hydrochloride gauzes in acute traumatic wounds in triage, a pilot study.
Topics: Administration, Topical; Adult; Emergency Service, Hospital; Female; Humans; Lidocaine; Male; Middle | 2016 |
Topical anaesthesia in children: reducing the need for specialty referral.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Child; Child Welfare; Child, Prescho | 2010 |
Effect of local anaesthesia and/or analgesia on pain responses induced by piglet castration.
Topics: Analgesia; Anesthesia, Local; Anesthetics, Local; Animal Welfare; Animals; Animals, Newborn; Anti-In | 2011 |
MEGX disposition in critically-ill trauma patients: subsequent assessments during the first week following trauma.
Topics: Adult; Aged; APACHE; Area Under Curve; Biomarkers; Critical Illness; Female; Half-Life; Humans; Lido | 2002 |
Pediatric wound triage protocols.
Topics: Anesthesia, Local; Child; Double-Blind Method; Emergency Service, Hospital; Epinephrine; Humans; Lid | 2003 |
EXPERIMENTAL ANALYSIS OF ISOMORPHIC (KOEBNER) RESPONSE IN PSORIASIS.
Topics: Chloroquine; Colchicine; Cold Temperature; Dermabrasion; Histology; Humans; Idoxuridine; Iontophores | 1964 |
THE MANAGEMENT OF CIVILIAN ARTERIAL INJURIES.
Topics: Adolescent; Amputation, Surgical; Aneurysm; Angiography; Arteries; Arteriovenous Fistula; Blood Vess | 1964 |
[OUR EXPERIENCE WITH REGIONAL ANESTHESIA, USING INTRAVENOUS ADMINISTRATION].
Topics: Administration, Intravenous; Anesthesia; Anesthesia, Conduction; Anesthesia, Intravenous; Cellulitis | 1963 |
TRAUMATIC INTRATHORACIC TIBIA.
Topics: Accidents; Accidents, Traffic; Black People; Blood Circulation; Blood Transfusion; Bone Transplantat | 1964 |
ROLE OF TRAUMA IN ISOMORPHIC RESPONSE IN PSORIASIS.
Topics: Biomedical Research; Chymotrypsin; Humans; Hyaluronoglucosaminidase; Hypothermia; Hypothermia, Induc | 1965 |
EXPERIENCES WITH INTRAVENOUS REGIONAL ANAESTHESIA.
Topics: Anesthesia; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthesiology; Humans; Lidocaine; Orth | 1965 |
Free radical-induced damage in experimental peripheral nerve injection injury.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Immunohistochemistry; Injury | 2003 |
Plain talk about wound pain.
Topics: Administration, Cutaneous; Algorithms; Anesthetics, Local; Chronic Disease; Decision Trees; Humans; | 2003 |
Changes in electrophysiological properties of regenerating rat peripheral nerves after crush injury.
Topics: 4-Aminopyridine; Action Potentials; Animals; Electric Stimulation; Electrophysiology; Female; Lidoca | 2004 |
Plain talk about wound pain.
Topics: Acute Disease; Anesthetics, Local; Attitude to Health; Chronic Disease; Humans; Lidocaine; Nursing A | 2005 |
Lidocaine depresses splenocyte immune functions following trauma-hemorrhage in mice.
Topics: Animals; Bone Marrow Cells; Cell Proliferation; Cell Survival; Concanavalin A; Cytokines; Enzyme Act | 2006 |
Investigation of drug delivery by iontophoresis in a surgical wound utilizing microdialysis.
Topics: Animals; Anti-Arrhythmia Agents; Calibration; Chromatography, High Pressure Liquid; Iontophoresis; L | 2008 |
Listen to the data when results are not significant.
Topics: Abortifacient Agents, Nonsteroidal; Administration, Inhalation; Administration, Oral; Adolescent; An | 2008 |
Tocainide protein binding in normal volunteers and trauma patients.
Topics: Anti-Arrhythmia Agents; Humans; Lidocaine; Orosomucoid; Protein Binding; Tocainide; Wounds and Injur | 1982 |
Alpha1-acid glycoprotein concentration and protein binding in trauma.
Topics: Adolescent; Adult; Female; Humans; Lidocaine; Male; Middle Aged; Orosomucoid; Protein Binding; Wound | 1982 |
Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure.
Topics: Adult; Aged; Bilirubin; Diagnosis, Differential; Female; Humans; Lidocaine; Liver Function Tests; Ma | 1995 |
Leukocyte hydrogen peroxide production in a surgical wound in mice. The effects of an amide local anaesthetic.
Topics: Anesthetics, Local; Animals; Diffusion Chambers, Culture; Hydrogen Peroxide; Inflammation; Leukocyte | 1996 |
Comparison of wound infection rates using plain versus buffered lidocaine for anesthesia of traumatic wounds.
Topics: Adult; Anesthetics, Local; Buffers; Emergencies; Female; Humans; Lidocaine; Logistic Models; Male; P | 1997 |
Topical analgesia for children.
Topics: Administration, Topical; Anesthetics, Local; Child; Cocaine; Drug Combinations; Epinephrine; Gels; H | 1997 |
Repairing lacerations in children.
Topics: Anesthetics, Local; Child; Child, Preschool; Cocaine; Dermatologic Surgical Procedures; Drug Therapy | 1997 |
The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Clonidine; Cold | 1998 |
The reasons for poor response to treatment of posttraumatic reflex sympathetic dystrophy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Calcitonin; Diuretics, | 1998 |
Tips on avoiding lidocaine infiltration for simple wound repairs and using LET effectively in the emergency department: one pediatric ED nurse's experience.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Child; Emergency Nursing; Epinep | 2000 |
The pharmacokinetics of morphine and lidocaine in nine severe trauma patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Female; Humans; Lidocaine; M | 1999 |
Emergency control of convulsions.
Topics: Anesthesia, General; Barbiturates; Benzodiazepines; Chlormethiazole; Emergencies; Humans; Lidocaine; | 1979 |
The use of drugs in emergency airway management in pediatric trauma.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia; Child; Child, Preschool; Clinical Protocols; Diazepam | 1992 |
Increasing flap survival: a new method.
Topics: Animals; Burns; Chloramphenicol; Infection Control; Infections; Lidocaine; Rats; Surgical Flaps; Swi | 1990 |
[The use of immobilized preparations for the control of suppurative-inflammatory complications and the pain syndrome in trauma and after the operation].
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Dimethylpolysiloxanes; Female; Humans; Lidocaine; M | 1988 |
How to remove tightly adherent gauze from open wounds.
Topics: Adult; Bandages; Female; Humans; Lidocaine; Solutions; Wounds and Injuries | 1987 |
Management of post-traumatic pain syndromes: report of 113 cases.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arm Injuries; Autonomic Nerve Block; Causalgia; C | 1973 |
Gas chromatography as a potential means of diagnosing arthritis. I. Differentiation between staphylococcal, streptococcal, gonococcal, and traumatic arthritis.
Topics: Anhydrides; Anti-Bacterial Agents; Arthritis; Arthritis, Infectious; Butyrates; Chromatography, Gas; | 1974 |
[The intravenous local anesthesia in surgery of accidents].
Topics: Accidents; Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Extremities; Female; | 1966 |
Inhibition of succinylcholine-induced increased intragastric pressure by nondepolarizing muscle relaxants and lidocaine.
Topics: Abdominal Muscles; Adolescent; Adult; Gallamine Triethiodide; Gastroesophageal Reflux; Humans; Intub | 1971 |
[Peripheral anesthesia in orthopedics and traumatology].
Topics: Anesthesia, Conduction; Bupivacaine; Humans; Lidocaine; Orthopedics; Wounds and Injuries | 1974 |
[Inhibitors of proteolysis in the treatment of thermal and mechanical injuries].
Topics: Aminocaproates; Animals; Aprotinin; Bradykinin; Burns; Humans; Kallidin; Lidocaine; Methionine; Mice | 1974 |
[Propofan as an antalgic in general surgery. Apropos of 50 cases].
Topics: Acetaminophen; Analgesics; Aspirin; Bone Diseases; Caffeine; Chlorpheniramine; Dextropropoxyphene; D | 1972 |
In vivo quantitation of local anesthetic suppression of leukocyte adherence.
Topics: Anesthetics, Local; Animals; Cell Adhesion; Cheek; Cricetinae; Leukocytes; Lidocaine; Microscopy; So | 1972 |
[Case of ventilatory disorders following blunt injury of the carotid artery].
Topics: Adult; Carotid Artery Injuries; Carotid Body; Humans; Lidocaine; Male; Respiratory Tract Diseases; W | 1972 |
[Personal experience with a new type of mixed anesthesia in orthopedics and traumatology].
Topics: Adolescent; Adult; Aged; Diazepam; Female; Fracture Fixation; Humans; Lidocaine; Male; Middle Aged; | 1969 |