Page last updated: 2024-11-08

alanine and Injuries

alanine has been researched along with Injuries in 21 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
"The role of leucine and alanine aminopeptidases is studied in two discrete biologic systems: experimental late stages of wound healing and carrageenan-induced intradermal granulomas in the rat."7.65Leucine and alanine aminopeptidase activities in experimentally induced intradermal granulomas and late stages of wound healing in the rat. ( Spector, GJ, 1977)
"In both nonseptic and septic trauma, increasing TPN increased the mean clearance rate of all infused AA."5.27Increased dependence of leucine in posttraumatic sepsis: leucine/tyrosine clearance ratio as an indicator of hepatic impairment in septic multiple organ failure syndrome. ( Belzberg, H; Coleman, B; Pittiruti, M; Placko, R; Sganga, G; Siegel, JH; Wedel, S; Wiles, CE, 1985)
"The role of leucine and alanine aminopeptidases is studied in two discrete biologic systems: experimental late stages of wound healing and carrageenan-induced intradermal granulomas in the rat."3.65Leucine and alanine aminopeptidase activities in experimentally induced intradermal granulomas and late stages of wound healing in the rat. ( Spector, GJ, 1977)
"In both nonseptic and septic trauma, increasing TPN increased the mean clearance rate of all infused AA."1.27Increased dependence of leucine in posttraumatic sepsis: leucine/tyrosine clearance ratio as an indicator of hepatic impairment in septic multiple organ failure syndrome. ( Belzberg, H; Coleman, B; Pittiruti, M; Placko, R; Sganga, G; Siegel, JH; Wedel, S; Wiles, CE, 1985)
"The data show that trauma accelerates the nitrogen flow and both protein synthesis and breakdown."1.26Whole-body protein metabolism due to trauma in man as estimated by L-[15N]alanine. ( Birkhahn, RH; Blakemore, WS; Fitkin, D; Jeevanandam, M; Long, CL, 1981)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199019 (90.48)18.7374
1990's1 (4.76)18.2507
2000's0 (0.00)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bazbouz, MB1
Tronci, G1
Sakamoto, A1
Moldawer, LL1
Palombo, JD1
Desai, SP1
Bistrian, BR1
Blackburn, GL2
Cuthbertson, DP1
Tischler, ME1
Birkhahn, RH1
Long, CL2
Fitkin, D1
Jeevanandam, M1
Blakemore, WS1
Freund, HR1
James, JH1
Fischer, JE2
Oppenheim, WL1
Williamson, DH3
Smith, R2
Freund, H1
Yoshimura, N1
Goldberg, AL1
Tischler, M1
Libby, P1
Brown, J1
Gore, DC1
Lee, R1
Wedge, JH1
De Campos, R1
Kerr, A1
Farrell, R1
Ilic, V1
Spector, GJ1
Imamura, M1
Clowes, GH1
O'Donnell, TF1
Trerice, M1
Bhimjee, Y1
Ryan, NT1
Kinney, JM1
Geiger, JW1
Wolfe, RR1
Jahoor, F1
Hartl, WH1
Hiraide, A1
Katayama, M1
Inoue, S1
Sugimoto, H1
Yoshioka, T1
Sugimoto, T1
Jorfeldt, L1
Lund, P1
Pittiruti, M1
Siegel, JH1
Sganga, G1
Coleman, B1
Wiles, CE1
Belzberg, H1
Wedel, S1
Placko, R1
Cahill, GF1
Aoki, TT1
Mäkinen, PL1
Raekallio, J1

Reviews

4 reviews available for alanine and Injuries

ArticleYear
Alterations in metabolism following injury: part II.
    Injury, 1980, Volume: 11, Issue:4

    Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Carbohydrate Metabolism; Endocrine Gland

1980
Hormonal regulation of protein degradation in skeletal and cardiac muscle.
    Life sciences, 1981, Jun-08, Volume: 28, Issue:23

    Topics: Adrenalectomy; Alanine; Animals; Corticosterone; Diabetes Mellitus, Experimental; Epinephrine; Fasti

1981
Protein and amino acid metabolism after injury.
    Diabetes/metabolism reviews, 1989, Volume: 5, Issue:2

    Topics: Alanine; Amino Acids; Bacterial Infections; Blood Proteins; Burns; Catecholamines; Glucagon; Glucoco

1989
Inter-tissue nitrogen fluxes.
    British medical bulletin, 1985, Volume: 41, Issue:3

    Topics: Alanine; Amino Acids; Animals; Erythrocytes; Glutamine; Glycine; Humans; Intestine, Small; Liver; Mu

1985

Trials

1 trial available for alanine and Injuries

ArticleYear
Dichloroacetate inhibits peripheral efflux of pyruvate and alanine during hormonally simulated catabolic stress.
    The Journal of surgical research, 1993, Volume: 54, Issue:6

    Topics: Adult; Alanine; Dichloroacetic Acid; Epinephrine; Glucagon; Glucose; Humans; Hydrocortisone; Male; M

1993

Other Studies

16 other studies available for alanine and Injuries

ArticleYear
Two-layer Electrospun System Enabling Wound Exudate Management and Visual Infection Response.
    Sensors (Basel, Switzerland), 2019, Feb-26, Volume: 19, Issue:5

    Topics: Alanine; Biological Dressings; Bromthymol Blue; Color; Drug Resistance, Bacterial; Humans; Hydrogen-

2019
Alterations in tyrosine and protein kinetics produced by injury and branched chain amino acid administration in rats.
    Clinical science (London, England : 1979), 1983, Volume: 64, Issue:3

    Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Kinetics; Male; Nitrogen; Pancreatitis;

1983
Whole-body protein metabolism due to trauma in man as estimated by L-[15N]alanine.
    The American journal of physiology, 1981, Volume: 241, Issue:1

    Topics: Alanine; Ammonia; Humans; Isotope Labeling; Kinetics; Male; Nitrogen; Nitrogen Isotopes; Proteins; U

1981
Nitrogen-sparing mechanisms of singly administered branched-chain amino acids in the injured rat.
    Surgery, 1981, Volume: 90, Issue:2

    Topics: Alanine; Amino Acids, Branched-Chain; Animals; Female; Isoleucine; Laparotomy; Leucine; Liver; Muscl

1981
Early biochemical changes and severity of injury in man.
    The Journal of trauma, 1980, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Alanine; Female; Fractures, Bone; Histidine; Humans; Ketones; Lactates; Mal

1980
The role of alanine in the nitrogen conserving quality of the branched-chain amino acids in the postinjury state.
    The Journal of surgical research, 1980, Volume: 29, Issue:1

    Topics: Alanine; Amino Acids, Branched-Chain; Animals; Gluconeogenesis; Muscles; Nitrogen; Rats; Wounds and

1980
Regulation of protein degradation in skeletal muscle.
    Biochemical Society transactions, 1980, Volume: 8, Issue:5

    Topics: Alanine; Amino Acids; Humans; Leucine; Methylhistidines; Muscle Proteins; Muscles; Starvation; Surgi

1980
Branched-chain amino acids, nitrogen excretion and injury in man.
    Clinical science and molecular medicine, 1976, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Alanine; Amino Acids; Blood Glucose; Body Height; Body Weight; Glutamates; Glycin

1976
Leucine and alanine aminopeptidase activities in experimentally induced intradermal granulomas and late stages of wound healing in the rat.
    Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 36, Issue:1

    Topics: Alanine; Aminopeptidases; Animals; Carrageenan; Fibroblasts; Granuloma; Isoenzymes; Leucyl Aminopept

1977
Liver metabolism and glucogenesis in trauma and sepsis.
    Surgery, 1975, Volume: 77, Issue:6

    Topics: Alanine; Animals; Autopsy; Energy Metabolism; Enzyme Precursors; Fatty Acids, Nonesterified; Female;

1975
Nonsuppressability of gluconeogenesis by glucose in septic patients.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:2

    Topics: Adult; Alanine; Female; Gluconeogenesis; Glucose; Humans; Infections; Liver; Male; Middle Aged; Musc

1976
[Effects of ketone bodies on postinjury metabolism in man].
    Nihon Geka Gakkai zasshi, 1988, Volume: 89, Issue:5

    Topics: Alanine; Humans; Ketone Bodies; Wounds and Injuries

1988
A standardized human model of moderate trauma. Quantitative studies of glucose turnover during cholecystectomy.
    Acta chirurgica Scandinavica. Supplementum, 1985, Volume: 522

    Topics: Adult; Alanine; Blood Glucose; Cholecystectomy; Glucose; Glycerol; Humans; Insulin; Lactates; Splanc

1985
Increased dependence of leucine in posttraumatic sepsis: leucine/tyrosine clearance ratio as an indicator of hepatic impairment in septic multiple organ failure syndrome.
    Surgery, 1985, Volume: 98, Issue:3

    Topics: Adolescent; Adult; Alanine; Amino Acids; Amino Acids, Essential; Aspartic Acid; Glutamates; Humans;

1985
How metabolism affects clinical problems.
    Medical times, 1970, Volume: 98, Issue:10

    Topics: Adrenal Cortex Hormones; Alanine; Blood Glucose; Brain; Carbohydrate Metabolism; Diabetic Ketoacidos

1970
Effect of hydrocortisone on aminopeptidase activation of early wound healing.
    Die Naturwissenschaften, 1967, Volume: 54, Issue:8

    Topics: Alanine; Aminopeptidases; Animals; Arginine; Hydrocortisone; Leucyl Aminopeptidase; Lysine; Male; Me

1967