Page last updated: 2024-11-02

pd 98059 and Injuries

pd 98059 has been researched along with Injuries in 3 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.

Research Excerpts

ExcerptRelevanceReference
" We hypothesized that administration of a specific mitogen-activated protein kinase inhibitor, PD 98059, at the end of resuscitation following severe hemorrhagic shock can reduce the plasma levels of interleukin 6 (IL-6) and hepatocellular damage."3.72The effect of inhibition of a major cell signaling pathway following trauma hemorrhage on hepatic injury and interleukin 6 levels. ( Bland, KI; Chaudry, IH; Jarrar, D; Kuebler, JF; Rue, LW; Song, GY, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lim, G1
Sung, B1
Ji, RR1
Mao, J1
Jarrar, D1
Song, GY1
Kuebler, JF1
Rue, LW1
Bland, KI1
Chaudry, IH1
Ellis, PD1
Hadfield, KM1
Pascall, JC1
Brown, KD1

Other Studies

3 other studies available for pd 98059 and Injuries

ArticleYear
Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Analgesics; Animals; Behavior, Animal; Benzoxazines; Enzyme Inhibitors; Flavonoids; Ligation; Male;

2003
The effect of inhibition of a major cell signaling pathway following trauma hemorrhage on hepatic injury and interleukin 6 levels.
    Archives of surgery (Chicago, Ill. : 1960), 2004, Volume: 139, Issue:8

    Topics: Analysis of Variance; Animals; Dinoprostone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; F

2004
Heparin-binding epidermal-growth-factor-like growth factor gene expression is induced by scrape-wounding epithelial cell monolayers: involvement of mitogen-activated protein kinase cascades.
    The Biochemical journal, 2001, Feb-15, Volume: 354, Issue:Pt 1

    Topics: Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Flavonoids; Gene Expression

2001