indomethacin has been researched along with Injuries in 21 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Injuries: Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy-eight patients, aged 12-87 years, with osteoarthritis or extremity trauma, attached one indomethacin patch (containing 96 mg indomethacin) to the most symptomatic site twice daily." | 9.08 | Clinical evaluation of indomethacin-containing patches for osteoarthritis and extremity trauma. ( Hatori, M; Kokubun, S, 1997) |
| "There was no statistical difference in the mean reduction in pain score between any of the combinations at any point, although combination therapy was the first to reach a clinically significant reduction in pain score (<13 mm), and diclofenac-paracetamol combinations consistently produced a greater reduction in mean pain score than either nonsteroidal antiinflammatory drugs or paracetamol alone." | 5.11 | Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury. ( Lam, PK; Man, SY; Rainer, TH; Woo, WW, 2005) |
| "Seventy-eight patients, aged 12-87 years, with osteoarthritis or extremity trauma, attached one indomethacin patch (containing 96 mg indomethacin) to the most symptomatic site twice daily." | 5.08 | Clinical evaluation of indomethacin-containing patches for osteoarthritis and extremity trauma. ( Hatori, M; Kokubun, S, 1997) |
| "Eighteen (90%) wounds in the saline-chitosan group and 11 (55%) wounds in the saline-gauze group were healed." | 1.42 | Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention. ( Hsu, JR; Noel, SP; Rathbone, CR; Rivera, JC; Wenke, JC, 2015) |
| "Circular burns were inflicted on anaesthetized animals which were killed 30 min, 2 h or 4 h after burning." | 1.26 | On the enzymatic response to injury and its mediators. ( Nieminen, L; Raekallio, J, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (85.71) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rivera, JC | 1 |
| Hsu, JR | 1 |
| Noel, SP | 1 |
| Wenke, JC | 1 |
| Rathbone, CR | 1 |
| Woo, WW | 1 |
| Man, SY | 1 |
| Lam, PK | 1 |
| Rainer, TH | 1 |
| Ellman, MH | 1 |
| Wang, BS | 1 |
| Heacock, EH | 1 |
| Mannick, JA | 1 |
| Collawn, SS | 1 |
| Rankin, JC | 1 |
| Ledford, BE | 1 |
| Baggett, B | 1 |
| Lundberg, C | 1 |
| Gerdin, B | 1 |
| Wisnieski, JJ | 1 |
| Joncic, DL | 1 |
| Chotigavanich, C | 1 |
| Lord, JT | 1 |
| Ziboh, VA | 1 |
| Cagle, WD | 1 |
| Kursunoglu, S | 1 |
| Redmond, G | 1 |
| Hatori, M | 1 |
| Kokubun, S | 1 |
| Raekallio, J | 1 |
| Nieminen, L | 1 |
| Vane, JR | 1 |
| McGiff, JC | 1 |
| Maibach, E | 1 |
| Faist, E | 1 |
| Kupper, TS | 1 |
| Baker, CC | 1 |
| Chaudry, IH | 1 |
| Dwyer, J | 1 |
| Baue, AE | 1 |
| Gavotto, AC | 1 |
| Palma, JA | 1 |
| Villagra, SB | 1 |
| Penners, R | 1 |
| Struck, H | 2 |
| Hernández-Richter, J | 2 |
| Sugano, T | 1 |
| Fujimori, I | 1 |
| Dittmar, FK | 1 |
| el-Salamouny, AR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Inflammatory Markers in Single Port Laparoscopic and Vaginal Hysterectomies: A Retrospective Study in Kocaeli, Northwest Turkey[NCT04221308] | 134 participants (Actual) | Observational | 2018-01-01 | Completed | |||
| Evaluation of Inflammatory Markers in Laparoscopic and Abdominal Hysterectomies: A Retrospective Study in Kocaeli, Northwest Turkey[NCT04184765] | 212 participants (Actual) | Observational | 2018-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for indomethacin and Injuries
| Article | Year |
|---|---|
Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dizziness; Female; Humans | 2005 |
Clinical evaluation of indomethacin-containing patches for osteoarthritis and extremity trauma.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non | 1997 |
European experiences with tolmetin in the treatment of rheumatic diseases.
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Ag | 1976 |
18 other studies available for indomethacin and Injuries
| Article | Year |
|---|---|
Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Prolife | 2015 |
Diagnosis and management of bursitis.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bursitis; Chondrocalcinosi | 1984 |
Characterization of suppressor cells generated in mice after surgical trauma.
Topics: Amputation, Surgical; Animals; Indomethacin; Macrophages; Male; Mice; Mice, Inbred Strains; Prostagl | 1982 |
Ornithine decarboxylase activity in the artificially stimulated decidual cell reaction in the mouse uterus.
Topics: Animals; Carboxy-Lyases; Cyclic AMP; Decidua; Diamines; Female; Indomethacin; Mice; Mice, Inbred ICR | 1981 |
The inflammatory reaction in an experimental model of open wounds in the rat. The effect of arachidonic acid metabolites.
Topics: Animals; Arachidonic Acids; Biotransformation; Dinoprostone; Granulation Tissue; Indomethacin; Infla | 1984 |
Trauma and Reiter's syndrome: development of 'reactive arthropathy' in two patients following musculoskeletal injury.
Topics: Adult; Arthritis, Reactive; HLA Antigens; HLA-B27 Antigen; Humans; Indomethacin; Knee Injuries; Male | 1984 |
[Inflammatory conditions and indomethacin. Modification of severe life-threatening infections following surgery and injuries with indomethacin].
Topics: Accidents, Traffic; Adult; Female; Humans; Indomethacin; Male; Peritonitis; Surgical Wound Infection | 1983 |
Comparative clinical evaluation of combiflex and indomethacin in traumatic diseases.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arginine; Child; Drug Combinations; Drug Evaluati | 1981 |
Prostaglandins in wound healing: possible regulation of granulation.
Topics: Animals; Arachidonic Acids; Guinea Pigs; Hexosamines; Indomethacin; Kinetics; Prostaglandins; Prosta | 1980 |
On the enzymatic response to injury and its mediators.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Burns; | 1979 |
Possible contributions of endogenous prostaglandins to the control of blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Cyclooxygenase Inhibitors; Homeostasis; Hyperem | 1975 |
Depression of cellular immunity after major injury. Its association with posttraumatic complications and its reversal with immunomodulation.
Topics: Adult; Cell Adhesion; Female; Humans; Immune Tolerance; Indomethacin; Lymphocyte Activation; Lymphoc | 1986 |
Depression of cellular immunity after major injury. Its association with posttraumatic complications and its reversal with immunomodulation.
Topics: Adult; Cell Adhesion; Female; Humans; Immune Tolerance; Indomethacin; Lymphocyte Activation; Lymphoc | 1986 |
Depression of cellular immunity after major injury. Its association with posttraumatic complications and its reversal with immunomodulation.
Topics: Adult; Cell Adhesion; Female; Humans; Immune Tolerance; Indomethacin; Lymphocyte Activation; Lymphoc | 1986 |
Depression of cellular immunity after major injury. Its association with posttraumatic complications and its reversal with immunomodulation.
Topics: Adult; Cell Adhesion; Female; Humans; Immune Tolerance; Indomethacin; Lymphocyte Activation; Lymphoc | 1986 |
Effects of indomethacin on plasma fibrinogen levels in rats with tissue injury.
Topics: Animals; Epinephrine; Ethanolamine; Ethanolamines; Female; Fibrinogen; Indomethacin; Medulla Oblonga | 1985 |
[Drug therapy of postoperative and post-traumatic edemas in orthopedics].
Topics: Congenital Abnormalities; Edema; Fracture Fixation; Humans; Indomethacin; Limb Deformities, Congenit | 1968 |
[Experimental studies on influencing wound healing].
Topics: Animals; Biomechanical Phenomena; Collagen; Hydroxyproline; Indomethacin; Rabbits; Rats; Stimulation | 1971 |
[Clinical aspecs of the anti-inflammatory drugs in the surgical and orthopedic fields].
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis; Gout; Humans; Indomethacin; Joint Diseases; Mefenam | 1970 |
[On the influence of an antipholgistic agent on wound healing in animal experiment].
Topics: Animals; Collagen; Indomethacin; Injections, Subcutaneous; Rabbits; Tendon Injuries; Wound Healing; | 1967 |
[Experiences with an indoleacetic acid derivate (Indomethacin) in the therapy of posttraumatic and postoperative edema].
Topics: Abscess; Cellulitis; Edema; Fractures, Bone; Humans; Indomethacin; Inflammation; Intestinal Neoplasm | 1968 |