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3,5-diiodothyronine and Hypothyroidism

3,5-diiodothyronine has been researched along with Hypothyroidism in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's3 (13.64)18.2507
2000's3 (13.64)29.6817
2010's12 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cioffi, F; Coppola, M; de Lange, P; Gentile, A; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Senese, R; Silvestri, E1
Damiano, F; Giudetti, AM; Gnoni, A; Paglialonga, G; Siculella, L1
Kannan, K; Kunisue, T; Little, AG; Seebacher, F1
Araujo, RL; da Silva Leandro, M; de Andrade, BM; de Carvalho, DP; de Castro, JP; de Souza dos Santos, MC; Ferreira, AC; Neto, RA; Padron, AS; Pantaleão, TU1
Brabant, G; Köhrle, J; Lehmphul, I; Ruchala, M; Strasburger, CJ; Wallaschofski, H; Wu, Z1
Brabant, G; Dörr, M; Friedrich, N; Homuth, G; Ittermann, T; Köhrle, J; Laqua, R; Lehmphul, I; Nauck, M; Pietzner, M; Schurmann, C; Völker, U; Völzke, H; Wallaschofski, H1
Busiello, RA; Cioffi, F; De Matteis, R; Goglia, F; Lanni, A; Lombardi, A; Senese, R1
Cavallo, A; Damiano, F; Gnoni, A; Sardanelli, AM; Siculella, L; Taurino, F1
Busiello, RA; de Lange, P; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Silvestri, E1
Damiano, F; Gnoni, A; Gnoni, GV; Mangiullo, R; Papa, S; Siculella, L; Zanotti, F1
Cavallo, A; Conte, E; Gnoni, A; Gnoni, GV; Papa, S; Siculella, L; Zanotti, F1
Busiello, RA; de Lange, P; De Matteis, R; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Napolitano, L; Senese, R1
Cavallo, A; Gnoni, A; Gnoni, GV; Papa, S; Priore, P; Zanotti, F1
García-G, C; López-Bojorquez, L; Nuñez, J; Orozco, A; Valverde-R, C1
Imura, H; Inada, M; Ishii, H; Mashio, Y; Naito, K; Nishikawa, M; Tanaka, K1
Burger, AG; Engler, D; Merkelbach, U; Steiger, G1
Goglia, F; Lanni, A; Lombardi, A; Moreno, M2
Beneduce, L; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Pinna, G; Silvestri, E1
Murphy, MP; O'Reilly, I1
Horst, C; Rokos, H; Seitz, HJ1
Faber, J; Friis, T; Hommel, E; Kirkegaard, C; Siersbaek-Nielsen, K1

Other Studies

22 other study(ies) available for 3,5-diiodothyronine and Hypothyroidism

ArticleYear
Differential Effects of 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine On Mitochondrial Respiratory Pathways in Liver from Hypothyroid Rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:6

    Topics: Animals; Diiodothyronines; Electron Transport; Hypothyroidism; Male; Mitochondria, Liver; Rats; Rats, Wistar; Triiodothyronine

2018
3,5-diiodo-L-thyronine increases de novo lipogenesis in liver from hypothyroid rats by SREBP-1 and ChREBP-mediated transcriptional mechanisms.
    IUBMB life, 2019, Volume: 71, Issue:7

    Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Diiodothyronines; Gene Expression Regulation; Hepatocytes; Hypothyroidism; Lipogenesis; Liver; Male; Rats; Rats, Wistar; Sterol Regulatory Element Binding Protein 1; Transcriptional Activation

2019
Thyroid hormone actions are temperature-specific and regulate thermal acclimation in zebrafish (Danio rerio).
    BMC biology, 2013, Mar-26, Volume: 11

    Topics: Acclimatization; Animals; Body Temperature Regulation; Dietary Supplements; Diiodothyronines; Hypothyroidism; Multivariate Analysis; Muscles; Organ Specificity; RNA, Messenger; Temperature; Thyroid Hormones; Triiodothyronine; Zebrafish

2013
Administration of 3,5-diiodothyronine (3,5-T2) causes central hypothyroidism and stimulates thyroid-sensitive tissues.
    The Journal of endocrinology, 2014, Volume: 221, Issue:3

    Topics: Animals; Basal Metabolism; Diiodothyronines; Dual Oxidases; Flavoproteins; Hypothalamo-Hypophyseal System; Hypothyroidism; Immunoblotting; Iodide Peroxidase; Iodides; Iodothyronine Deiodinase Type II; Kidney; Liver; Male; NADPH Oxidase 4; NADPH Oxidases; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Thyrotropin; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2014
Detection of 3,5-diiodothyronine in sera of patients with altered thyroid status using a new monoclonal antibody-based chemiluminescence immunoassay.
    Thyroid : official journal of the American Thyroid Association, 2014, Volume: 24, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Diiodothyronines; Female; Humans; Hyperthyroidism; Hypothyroidism; Immunoassay; Luminescent Measurements; Male; Middle Aged; Sensitivity and Specificity; Young Adult

2014
Translating pharmacological findings from hypothyroid rodents to euthyroid humans: is there a functional role of endogenous 3,5-T2?
    Thyroid : official journal of the American Thyroid Association, 2015, Volume: 25, Issue:2

    Topics: Adult; Aged; Diiodothyronines; Female; Humans; Hypothyroidism; Leptin; Male; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult

2015
3,5-Diiodo-L-thyronine activates brown adipose tissue thermogenesis in hypothyroid rats.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Adipose Tissue, Brown; Analysis of Variance; Animals; Blotting, Western; Body Weights and Measures; Cell Respiration; Diiodothyronines; Energy Metabolism; Histological Techniques; Hypothyroidism; Immunohistochemistry; Mitochondria; Rats; Thermogenesis

2015
Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats stimulates bioenergetic parameters in liver mitochondria.
    Journal of bioenergetics and biomembranes, 2016, Volume: 48, Issue:5

    Topics: Animals; Diiodothyronines; Electron Transport; Energy Metabolism; Fatty Acids; Hypothyroidism; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Rats; Uncoupling Agents

2016
3,5-Diiodo-L-thyronine rapidly enhances mitochondrial fatty acid oxidation rate and thermogenesis in rat skeletal muscle: AMP-activated protein kinase involvement.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:3

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Body Temperature Regulation; Diiodothyronines; Disease Models, Animal; Fatty Acids; Hypothyroidism; Male; Mitochondria; Muscle, Skeletal; Oxidation-Reduction; Phosphorylation; Rats; Rats, Wistar

2009
3,5-diiodo-L-thyronine upregulates rat-liver mitochondrial F(o)F(1)-ATP synthase by GA-binding protein/nuclear respiratory factor-2.
    Biochimica et biophysica acta, 2010, Volume: 1797, Issue:2

    Topics: Animals; Chromatin Immunoprecipitation; Diiodothyronines; GA-Binding Protein Transcription Factor; Hypothyroidism; Immunoblotting; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Proton-Translocating ATPases; Oxygen Consumption; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2010
3,5-diiodo-L-thyronine increases FoF1-ATP synthase activity and cardiolipin level in liver mitochondria of hypothyroid rats.
    Journal of bioenergetics and biomembranes, 2011, Volume: 43, Issue:4

    Topics: Adenosine Triphosphate; Animals; Cardiolipins; Diiodothyronines; Hypothyroidism; Lipid Metabolism; Male; Mitochondria, Liver; Mitochondrial Membranes; Proton-Translocating ATPases; Rats; Rats, Wistar; RNA, Messenger

2011
Responses of skeletal muscle lipid metabolism in rat gastrocnemius to hypothyroidism and iodothyronine administration: a putative role for FAT/CD36.
    American journal of physiology. Endocrinology and metabolism, 2012, Nov-15, Volume: 303, Issue:10

    Topics: Animals; Blotting, Western; Calorimetry, Indirect; CD36 Antigens; Cell Line; Diiodothyronines; Fatty Acids, Nonesterified; Hypothyroidism; Immunohistochemistry; Lipid Metabolism; Male; Mice; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Triiodothyronine

2012
3,5-Diiodo-L-thyronine administration to hypothyroid rats rapidly enhances fatty acid oxidation rate and bioenergetic parameters in liver cells.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Animals; Cells, Cultured; Diiodothyronines; Energy Metabolism; Fatty Acids; Hepatocytes; Hypothyroidism; Male; Mitochondria; Oxidation-Reduction; Rats; Rats, Wistar

2013
3,5-Diiodothyronine in vivo maintains euthyroidal expression of type 2 iodothyronine deiodinase, growth hormone, and thyroid hormone receptor beta1 in the killifish.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:2

    Topics: Animals; Diiodothyronines; Fundulidae; Gene Expression Regulation, Enzymologic; Growth Hormone; Hyperthyroidism; Hypothyroidism; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Liver; Male; Response Elements; RNA, Messenger; Thyroid Gland; Thyroid Hormone Receptors beta; Up-Regulation

2007
Serum concentrations of 3, 3'-diiodothyronine, 3', 5'-diiodothyronine, and 3, 5-diiodothyronine in altered thyroid states.
    Endocrinologia japonica, 1983, Volume: 30, Issue:2

    Topics: Adult; Diiodothyronines; Humans; Hyperthyroidism; Hypothyroidism; Middle Aged; Thyronines; Thyroxine; Triiodothyronine

1983
The monodeiodination of triiodothyronine and reverse triiodothyronine in man: a quantitative evaluation of the pathway by the use of turnover rate techniques.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:1

    Topics: Chemical Precipitation; Chromatography, Ion Exchange; Chromatography, Paper; Diiodothyronines; Humans; Hypothyroidism; Immunochemistry; Iodine; Metabolic Clearance Rate; Radioimmunoassay; Triiodothyronine; Triiodothyronine, Reverse

1984
Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine.
    Molecular and cellular endocrinology, 1994, Volume: 99, Issue:1

    Topics: Animals; Body Weight; Diiodothyronines; Electron Transport Complex IV; Energy Metabolism; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Liver; Male; Mitochondria, Liver; Organ Size; Rats; Rats, Wistar; Triiodothyronine

1994
3,5-Diiodo-L-thyronine and 3,5,3'-triiodo-L-thyronine both improve the cold tolerance of hypothyroid rats, but possibly via different mechanisms.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:3

    Topics: Adaptation, Physiological; Adipose Tissue, Brown; Animals; Body Weight; Cold Temperature; Diiodothyronines; Energy Metabolism; Hypothyroidism; Liver; Male; Muscle, Skeletal; Myocardium; Organ Size; Oxygen Consumption; Rats; Rats, Wistar; Triiodothyronine

1998
Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?
    Endocrinology, 2002, Volume: 143, Issue:2

    Topics: Animals; Antithyroid Agents; Basal Metabolism; Dactinomycin; Diiodothyronines; Enzyme Inhibitors; Hypothyroidism; Iodide Peroxidase; Iopanoic Acid; Liver; Male; Propylthiouracil; Protein Synthesis Inhibitors; Radioimmunoassay; Rats; Rats, Wistar; Thyroid Gland; Triiodothyronine

2002
Treatment of hypothyroid rats with T2 (3,5-di-iodo-L-thyronine) rapidly stimulates respiration in subsequently isolated mitochondria.
    Biochemical Society transactions, 1992, Volume: 20, Issue:1

    Topics: Animals; Cycloheximide; Diiodothyronines; Hypothyroidism; Kinetics; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Propylthiouracil; Rats; Rats, Inbred Strains

1992
Rapid stimulation of hepatic oxygen consumption by 3,5-di-iodo-L-thyronine.
    The Biochemical journal, 1989, Aug-01, Volume: 261, Issue:3

    Topics: Animals; Diiodothyronines; Hypothyroidism; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Inbred Strains; Stimulation, Chemical; Thyronines; Thyroxine; Triiodothyronine, Reverse

1989
Urinary excretion of unconjugated and conjugated 3,5-diiodothyronine.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:2

    Topics: Adult; Aged; Diiodothyronines; Female; Glucuronates; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Radioimmunoassay; Sulfates; Thyronines

1985