indomethacin has been researched along with Hypothyroidism in 4 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anti-inflammatory activity of Indomethacin, Oxametacine and Phenylbutazone was evaluated in these animals using paw oedema provoked by carrageenan granulomas induced by cotton pellets and polyarthritis induced by Freund complete adjuvant." | 3.66 | The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents. ( Cirillo, R; Curzio, M; Franzone, J; Sena, L; Torrielli, MV, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franzone, J | 2 |
| Natale, T | 1 |
| Negro, F | 1 |
| Curzio, M | 2 |
| Torrielli, MV | 2 |
| Sena, LM | 1 |
| Iwaoka, T | 1 |
| Umeda, T | 1 |
| Nakayama, M | 1 |
| Shimada, T | 1 |
| Fujii, Y | 1 |
| Miura, F | 1 |
| Sato, T | 1 |
| Sena, L | 1 |
| Cirillo, R | 1 |
| Kobayashi, K | 1 |
| Shimomura, Y | 1 |
| Mori, M | 1 |
| Kamio, S | 1 |
| Fukuda, H | 1 |
4 other studies available for indomethacin and Hypothyroidism
| Article | Year |
|---|---|
[Influence of thyroid states on PGE2 biosynthesis].
Topics: Animals; Biological Assay; Dinoprostone; Hyperthyroidism; Hypothyroidism; Indomethacin; Male; Phenyl | 1981 |
A case of membranous nephropathy associated with thyroid antigens.
Topics: Antigens; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Humans; Hypothyroidism; I | 1982 |
The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema; | 1981 |
[Effects of clinically used drugs on pituitary hormone secretion].
Topics: Chlorophenols; Glycolates; Humans; Hypothyroidism; Indomethacin; Meclofenoxate; Thyrotropin | 1978 |