Page last updated: 2024-11-04

spiperone and Hypothyroidism

spiperone has been researched along with Hypothyroidism in 6 studies

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
" Additional Long-Evans rats were made hyperthyroid with a daily injection of triiodothyronine (T3) through the first 29 days of age."3.66Effects of neonatal dysthyroidism on serotonin type 1 and type 2 receptors in rat brain. ( Biassoni, R; Timiras, PS; Vaccari, A, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jahnke, G1
Nicholson, G1
Greeley, GH1
Youngblood, WW1
Prange, AJ1
Kizer, JS1
Crocker, AD2
Overstreet, DH2
Vaccari, A2
Biassoni, R1
Timiras, PS1
Gessa, G1
Kalaria, RN1
Prince, AK1
Crocker, JM1

Other Studies

6 other studies available for spiperone and Hypothyroidism

ArticleYear
Studies of the neural mechanisms by which hypothyroidism decreases prolactin secretion in the rat.
    Brain research, 1980, Jun-09, Volume: 191, Issue:2

    Topics: Animals; Caudate Nucleus; Dopamine; Haloperidol; Hypothalamo-Hypophyseal System; Hypothyroidism; Mal

1980
Modification of the behavioural effects of haloperidol and of dopamine receptor regulation by altered thyroid status.
    Psychopharmacology, 1984, Volume: 82, Issue:1-2

    Topics: Animals; Behavior, Animal; Body Temperature; Catalepsy; Haloperidol; Humans; Hyperthyroidism; Hypoth

1984
Effects of neonatal dysthyroidism on serotonin type 1 and type 2 receptors in rat brain.
    European journal of pharmacology, 1983, Nov-11, Volume: 95, Issue:1-2

    Topics: Animals; Animals, Newborn; Brain; Female; Hyperthyroidism; Hypothyroidism; Iodides; Male; Methimazol

1983
[3H]tyramine binding: a comparison with neuronal [3H]dopamine uptake and [3H]mazindol binding processes.
    Neurochemical research, 1989, Volume: 14, Issue:10

    Topics: Animals; Cattle; Corpus Striatum; Dopamine; Hypothyroidism; Indoles; Male; Mazindol; Rats; Rats, Inb

1989
Decreased neurotransmitter receptor binding in striatum and cortex from adult hypothyroid rats.
    Brain research, 1986, Feb-05, Volume: 364, Issue:2

    Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Dioxanes; gamma-Aminobutyric Acid; Glutamate

1986
Hypothyroidism leads to increased dopamine receptor sensitivity and concentration.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:6

    Topics: Animals; Apomorphine; Body Temperature; Conditioning, Operant; Haloperidol; Hypothyroidism; Male; Ra

1986