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aspirin and Hypothyroidism

aspirin has been researched along with Hypothyroidism in 19 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"A patient with hypothyroidism had ingested aspirin and bled profusely following dental extraction."7.67Hemostatic defects in response to aspirin challenge in hypothyroidism. ( Bezek, EA; Hasiba, U; Lewis, JH; Vagnucci, AH; West, VA; Zeigler, ZR, 1986)
" The evidence demonstrates that the treatments to consider are first-trimester progesterone administration, levothyroxine in women with subclinical hypothyroidism, and the combination of aspirin and heparin in women with antiphospholipid antibodies."5.41Interventions to prevent miscarriage. ( Coomarasamy, A; Devall, A; Dhillon-Smith, RK; Fox, E; Kaur, R; Melo, P; Woodhead, N, 2023)
" In normal female rats, the sera total thyroxine (TT4) and total triiodothyronine (TT3) levels were detectably increased at day 10 post-partum than those at day 10 of pregnancy."3.78Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II-the developmental pattern of neurons in relation to oxidative stress and antioxidant defense system. ( Abd El-Tawab, SM; Ahmed, OM; Ahmed, RG; El-Bakry, AM; El-Gareib, AW, 2012)
" The dog had a history of hypothyroidism, which was controlled with levothyroxine."3.72Portal vein and aortic thromboses in a Siberian husky with ehrlichiosis and hypothyroidism. ( Bressler, C; Himes, LC; Moreau, RE, 2003)
"A patient with hypothyroidism had ingested aspirin and bled profusely following dental extraction."3.67Hemostatic defects in response to aspirin challenge in hypothyroidism. ( Bezek, EA; Hasiba, U; Lewis, JH; Vagnucci, AH; West, VA; Zeigler, ZR, 1986)
"We report a case of type 2 diabetes mellitus presenting hypothyroidism due to overeating of seaweed that was noticed as a result of a discrepancy between glycated albumin (GA) and glycated hemoglobin (GHb)."1.33A case of type 2 diabetes mellitus developing hypothyroidism discovered as a result of a discrepancy between glycated hemoglobin and glycated albumin values. ( Arai, H; Hataya, Y; Hosoda, K; Kanamoto, N; Moriyama, K; Nakao, K; Nanbu, T, 2006)
"Aspirin may directly increase cholesterol transport into bile or have cell membrane effects which alter cholesterol transport."1.30Oral acetylsalicylic acid induces biliary cholesterol secretion in the rat. ( Gebhard, RL; Prigge, WF, 1997)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's3 (15.79)18.2507
2000's5 (26.32)29.6817
2010's1 (5.26)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Dhillon-Smith, RK1
Melo, P1
Kaur, R1
Fox, E1
Devall, A1
Woodhead, N1
Coomarasamy, A1
Schwier, NC1
O'Neal, K1
Ionescu, CN1
Chrissoheris, M1
Caraccciolo, EA1
Ghannoum, JE1
Odingo, NA1
Provost, N1
Ahmed, OM1
Ahmed, RG1
El-Gareib, AW1
El-Bakry, AM1
Abd El-Tawab, SM1
Zindrou, D1
Taylor, KM1
Bagger, JP1
MURPHY, BE1
PATTEE, CJ1
RIVIN, AU1
NUTTALL, FQ1
DOE, RP1
Bressler, C1
Himes, LC1
Moreau, RE1
Moriyama, K1
Kanamoto, N1
Hataya, Y1
Nanbu, T1
Hosoda, K1
Arai, H1
Nakao, K1
Faix, JD1
Rosen, HN1
Velazquez, FR1
Mehrotra, K1
Morgenstern, R1
Lundqvist, G1
Becedas, L1
Bengtsson Ahlberg, M1
Georgellis, A1
Prigge, WF1
Gebhard, RL1
Nicholson, G1
Liebling, LI1
Hall, RA1
Zeigler, ZR1
Hasiba, U1
Lewis, JH1
Vagnucci, AH1
West, VA1
Bezek, EA1
Kolendorf, K1
Siersbaek-Nielsen, K1
Hansen, MJ1
Friis, T1
Wright, MG1
Hawtrey, CE1
Williams, JJ1
Schmidt, JD1

Reviews

2 reviews available for aspirin and Hypothyroidism

ArticleYear
Interventions to prevent miscarriage.
    Fertility and sterility, 2023, Volume: 120, Issue:5

    Topics: Abortion, Habitual; Abortion, Spontaneous; Aspirin; Female; Heparin; Humans; Hypothyroidism; Pregnan

2023
Pharmacotherapeutic Management Strategies for Thyroid Disease-Induced Pericarditis.
    The Annals of pharmacotherapy, 2020, Volume: 54, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colchicine; Drug Interact

2020

Other Studies

17 other studies available for aspirin and Hypothyroidism

ArticleYear
Spontaneous coronary artery dissection and severe hypothyroidism.
    The Journal of invasive cardiology, 2009, Volume: 21, Issue:4

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Aspirin; Clopi

2009
Clinico-pathologic conference: case 6.
    Head and neck pathology, 2009, Volume: 3, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell;

2009
Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II-the developmental pattern of neurons in relation to oxidative stress and antioxidant defense system.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2012, Volume: 30, Issue:6

    Topics: Age Factors; alpha-Tocopherol; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Ascorb

2012
Excess coronary artery bypass graft mortality among women with hypothyroidism.
    The Annals of thoracic surgery, 2002, Volume: 74, Issue:6

    Topics: Aged; Aspirin; Coronary Artery Bypass; Diuretics; Female; Humans; Hypothyroidism; Male; Middle Aged;

2002
DETERMINATION OF THYROXINE UTILIZING THE PROPERTY OF PROTEIN-BINDING.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Aspirin; Bilirubin; Blood Chemical Analysis; Blood Proteins; Cholesterol; Glucose; Heparin; Hyperthy

1964
FALSE ENDOCRINE TEST RESULTS DUE TO DRUGS.
    California medicine, 1964, Volume: 101

    Topics: 17-Ketosteroids; Aspirin; Diagnosis, Differential; Hypnotics and Sedatives; Hypopituitarism; Hypothy

1964
THE ACHILLES REFLEX IN THYROID DISORDERS; A CRITICAL EVALUATION.
    Annals of internal medicine, 1964, Volume: 61

    Topics: Achilles Tendon; Adrenocorticotropic Hormone; Aging; Anemia; Anemia, Pernicious; Aspirin; Cold Tempe

1964
Portal vein and aortic thromboses in a Siberian husky with ehrlichiosis and hypothyroidism.
    The Journal of small animal practice, 2003, Volume: 44, Issue:9

    Topics: Animals; Aorta, Thoracic; Aspirin; Diagnosis, Differential; Dog Diseases; Dogs; Doxycycline; Ehrlich

2003
A case of type 2 diabetes mellitus developing hypothyroidism discovered as a result of a discrepancy between glycated hemoglobin and glycated albumin values.
    Diabetes research and clinical practice, 2006, Volume: 71, Issue:3

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Cell Count; Diabetes Mellitus, Type 2; Diet; Female; G

2006
Indirect estimation of thyroid hormone-binding proteins to calculate free thyroxine index: comparison of nonisotopic methods that use labeled thyroxine ("T-uptake")
    Clinical chemistry, 1995, Volume: 41, Issue:1

    Topics: Aspirin; Autoanalysis; Furosemide; Humans; Hyperthyroidism; Hypothyroidism; Immunoassay; Oleic Acid;

1995
Effects of peroxisome proliferators and/or hypothyroidism on xenobiotic-metabolizing enzymes in rat testis.
    Chemico-biological interactions, 1997, May-02, Volume: 104, Issue:2-3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arylsulfotransferase; Aspiri

1997
Oral acetylsalicylic acid induces biliary cholesterol secretion in the rat.
    Lipids, 1997, Volume: 32, Issue:7

    Topics: Administration, Oral; Animals; Aspirin; Bile; Cholesterol; Cholesterol Esters; Diet, Fat-Restricted;

1997
Thyroid dysfunction in female psychiatric patients.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 129

    Topics: Adult; Age Factors; Aged; Aspirin; Female; Humans; Hypothyroidism; Lithium; Mental Disorders; Middle

1976
Hemostatic defects in response to aspirin challenge in hypothyroidism.
    American journal of hematology, 1986, Volume: 23, Issue:4

    Topics: Aspirin; Bleeding Time; Blood Coagulation Disorders; Blood Platelets; Hemostasis; Humans; Hypothyroi

1986
Evaluation of thyroid status with "effective thyroxine ratio" (E.T.R.).
    Acta endocrinologica, 1974, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Depression, Chemical; Estrogens; Evaluation Studies as Topic; Fema

1974
Rheumatoid laryngitis.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:11

    Topics: Aged; Aspirin; Humans; Hypothyroidism; Iodine Radioisotopes; Laryngitis; Male; Pleurisy; Prednisolon

1973
Cystitis emphysematosa.
    Urology, 1974, Volume: 3, Issue:5

    Topics: Adult; Aspirin; Cephalexin; Cystitis; Cystoscopy; Diabetes Complications; Diabetes Mellitus; Diet, D

1974