oxazepam has been researched along with Hypothyroidism in 3 studies
Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of severe hypothyroidism on the pharmacokinetics and pharmacodynamics of oxazepam 15 mg given orally (n = 10) and the metabolism of paracetamol 750 mg given intravenously (n = 8) was investigated before and after treatment with levothyroxine." | 7.68 | Pharmacokinetics and pharmacodynamics of oxazepam and metabolism of paracetamol in severe hypothyroidism. ( Andreasen, F; Boesgaard, S; Døssing, M; Hansen, JM; Loft, S; Poulsen, HE; Sonne, J, 1990) |
| " The effect of severe hypothyroidism on the pharmacokinetics and pharmacodynamics of oxazepam 15 mg given orally (n = 10) and the metabolism of paracetamol 750 mg given intravenously (n = 8) was investigated before and after treatment with levothyroxine." | 3.68 | Pharmacokinetics and pharmacodynamics of oxazepam and metabolism of paracetamol in severe hypothyroidism. ( Andreasen, F; Boesgaard, S; Døssing, M; Hansen, JM; Loft, S; Poulsen, HE; Sonne, J, 1990) |
| "The pharmacokinetics of oxazepam, a drug mainly eliminated by a single step glucuronidation reaction, were studied in seven hyperthyroid and six hypothyroid patients before and after treatment." | 3.67 | Oxazepam pharmacokinetics in thyroid disease. ( Bewsher, PD; Hawksworth, GM; Khir, AS; Scott, AK, 1984) |
| " It was a prerequisite to establish the bioavailability of oxazepam prior to succeeding studies on the oral disposition of the drug." | 2.38 | Factors and conditions affecting the glucuronidation of oxazepam. ( Sonne, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scott, AK | 1 |
| Khir, AS | 1 |
| Bewsher, PD | 1 |
| Hawksworth, GM | 1 |
| Sonne, J | 2 |
| Boesgaard, S | 1 |
| Poulsen, HE | 1 |
| Loft, S | 1 |
| Hansen, JM | 1 |
| Døssing, M | 1 |
| Andreasen, F | 1 |
1 review available for oxazepam and Hypothyroidism
| Article | Year |
|---|---|
Factors and conditions affecting the glucuronidation of oxazepam.
Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Biological Availability; Biotransformation; Die | 1993 |
2 other studies available for oxazepam and Hypothyroidism
| Article | Year |
|---|---|
Oxazepam pharmacokinetics in thyroid disease.
Topics: Adult; Bilirubin; Female; Glucuronosyltransferase; Humans; Hyperthyroidism; Hypothyroidism; Kinetics | 1984 |
Pharmacokinetics and pharmacodynamics of oxazepam and metabolism of paracetamol in severe hypothyroidism.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Female; Humans; Hypothyroidism; Infusions, Intrave | 1990 |